Updated on 2026/09/06

写真a

 
Tsukada Yayoi Tetsuou
 
Affiliation
Musashikosugi Hospital, Division of General Medicine, Clinical Professor
Title
Clinical Professor
Homepage
https://www.nms.ac.jp/kosugi-h/section/soushin.html
Profile

Dr. Yayoi Tetsuou Tsukada is Associate Professor of General Medicine and Health Science at Nippon Medical School Graduate School of Medicine, and Vice Director and Hospital Professor at Nippon Medical School Musashi Kosugi Hospital, where she also directs the Center for Emergency and General Medicine.

She earned her MD from Nippon Medical School in 1988 and her PhD in 2003, and trained in cardiology and intensive care before spending two years as a visiting research fellow at The Scripps Research Institute in the United States.

Her research bridges cardiology and engineering. She leads the development and clinical translation of Tensor Cardiography, a novel electrocardiographic technique that quantifies the spatiotemporal transition of myocardial action potentials, supported by AMED and JSPS funding. Her wider programme covers ECG standardisation and the concept of the lifelong ECG, wearable monitoring, sex differences and multimorbidity in nationwide clinical data, and the cardiovascular impact of climate change. Her unifying aim is to transform the electrocardiogram from a record for diagnosis into information for prevention.

Dr. Tsukada serves as Executive Board Member of the Japanese Circulation Society and Chair of its Prevention Committee, and previously chaired its Diversity Promotion Committee. She was chair of the writing group and first author of the JCS/JCC/JACR/JATS 2024 Guideline on Cardiovascular Practice with Consideration for Diversity, Equity and Inclusion. She advises the Ministry of Health, Labour and Welfare on cardiovascular disease control and public health communication, and serves on its Labour Insurance Appeals Board.

She was the first woman to chair the Kanto-Koshinetsu Regional Meeting of the Japanese Circulation Society, and is an active advocate for cardiovascular prevention, sex- and gender-based medicine, and health equity in Japan and internationally.

External link

Degree

  • MD,PhD ( Nippon Medical School )

Research Interests

  • Cardiovascular medicine

  • Medical Information and Communication Technology

  • General medicine

  • Multiple Chronic Conditions (MCC)

  • Digital health, Digital medicine

  • multimorbidity

  • Lifestyle disease

  • Remote monitoring

  • ECG

  • Heart failure

  • Social Determinant of Health

Research Areas

  • Informatics / Life, health and medical informatics

  • Life Science / Cardiology

  • Life Science / General internal medicine  / General Medicine

Education

  • Nippon Medical School   School of Medicine

    1982.4 - 1988.3

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Research History

  • Nippon Medical School Musashi-Kosugi Hospital   Clinical Professor

    2020.10

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  • Nippon Medical School   General Medicine・Health Science   Associate Professor

    2020.4

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  • Nippon Medical School Musashi-Kosugi Hospital   Vice-President

    2020.4

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  • The Scripps Research Institute   Department of Morecular Experiment Medicine   Visiting Scientist

    2003.9 - 2005.8

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  • Nippon Medical School   Department of General Medicine and Health Science   Senior Assistant Professor

    2018.10 - 2020.3

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  • Musashi Kosugi Hospital, Nippon Medical School   Department of ER and General Medicine   Director

    2018.8

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  • Nippon Medical School Hospital   The Department of Cardiovascular Medicine   Senior Assistant Professor

    2012.10 - 2018.6

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  • Nippon Medical School   Student Health Support   School Physician

    2010.4 - 2018.3

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  • Nippon Medical School Hospital   The First Department of Internal Medicine（   Assistant Professor

    1999.10 - 2012.9

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  • Nippon Medical School Hospital   The First Department of Internal Medicine   Fellow

    1997.4 - 1999.9

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  • Nippon Medical School Hospital   The First Department of Internal Medicine   Assistant Professor

    1997.1 - 1997.3

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  • Nippon Medical School Hospital   The First Department of Internal Medicine   Fellow

    1995.7 - 1996.12

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  • Nippon Medical School Hospital   Intencive Care Unit / Coronary Care Unit   Assistant Professor

    1995.4 - 1995.6

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  • Tama Nagayama Hospital, Nippon Medical School   Department of Internal Medicine   Assistant Professor

    1994.9 - 1995.3

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  • Nippon Medical School Hospital   The First Department of Internal Medicine   Fellow

    1992.7 - 1994.8

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  • Fussa General Hospital   Internal Medicine

    1990.6 - 1992.6

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  • Nippon Medical School Hospital   The 1st Department of Medicine   Resident

    1989.10 - 1990.5

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  • Tama Nagayama Hospital   Internal Medicine   Resident

    1988.6 - 1989.9

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Professional Memberships

  • Japanese College of Angiology

    2024.11

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  • The Japanese Society of Cardiovascular Disease Prevention

    2023.4

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  • The Japanese Circulation Society

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  • Japanese Society of Hospital General Medicine

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  • JAPAN PRIMARY CARE ASSOCIATION

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  • Japanese College of Cardiology

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  • THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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  • 日本骨粗鬆症学会

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  • JAPAN ASSOCIATION FOR MEDICAL INFORMATICS

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Committee Memberships

  • The Japanese Society of Cardiovascular Disease Prevention   a council member  

    2024.5   

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    Committee type：Academic society

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  • Labor Insurance Appeal Committee   a member of a committee  

    2024.3   

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    Committee type：Government

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  • Japanese Medical Specialty Board   Japanese Board of General Medicine (JBGM)  

    2022.8   

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    Committee type：Academic society

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  • Japanese Circulation Society   Managing Director  

    2022.7   

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    Committee type：Academic society

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  • Japanese Circulation Society   Chair of Prevention Committee  

    2022.7   

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    Committee type：Academic society

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  • Japan Primary Care Association   Delegates  

    2019.11   

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    Committee type：Academic society

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  • Japanese Society of Hospital Medicine   Delegates  

    2019.9   

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    Committee type：Academic society

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  • Japanese Circulation Society   Director  

    2020.7 - 2022.6   

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    Committee type：Academic society

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  • Japanese Circulation Society   Chair of Diversity Promotion Comitte  

    2020.7 - 2022.6   

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    Committee type：Academic society

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  • Japanese Circulation Society   Certification Committee  

    2020.7 - 2022.6   

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    Committee type：Academic society

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  • Japanese Medical Specialty Board   Japanese Board of General Medicine  

    2020.6 - 2020.7   

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    Committee type：Other

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  • Federation of National Health Insurance Associations of Kanagawa prefecture   Medical Fees Review Committee  

    2019.4 - 2022.8   

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    Committee type：Municipal

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  • Japanese Circularion Society   Diversity Promotion Comittee  

    2018.6   

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    Committee type：Academic society

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  • Central Ethics Committee   Nippon Medical School  

    2016.4   

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    Committee type：Academic society

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  • Japanese Circulation Society   Delegates  

    2012.4   

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    Committee type：Academic society

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Papers

  • Social determinants of cardiovascular health: From prevention to care and emerging challenges. Reviewed International journal

    Haruyo Yasui, Atsushi Mizuno, Yayoi Tetsuou Tsukada

    Journal of cardiology   2026.7

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    Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)  

    Cardiovascular disease (CVD) is the leading cause of mortality globally and imposes a substantial disease burden. Addressing the social determinants of health (SDOH) presents a critical opportunity to reduce CVD-related mortality and disability. In Japan, CVD constitutes a major cause of death and necessitates long-term care, with current guidelines now incorporating SDOH related to CVD, indicative of a growing interest in these determinants. This review outlines the definition and conceptual frameworks of SDOH, along with its key domains: (1) Economic stability, (2) Education access and quality, (3) Social and community context, (4) Health care access and quality, and (5) Neighborhood and built environment. In addition to these established determinants, we discuss emerging SDOH such as climate change and digital health technologies, which may reshape cardiovascular risk and potentially widen existing disparities. We also summarize existing epidemiological findings and implications for intervention strategies, and outline future perspectives, including the implications of genetic testing and related ethical, legal, and social issues, as well as strategies aimed at reducing health disparities. Overall, advancing equitable cardiovascular health will require continued research, greater recognition of the role of SDOH, and efforts to address these determinants, including improving understanding of SDOH among health care professionals and the public and strengthening the evidence base for CVD and SDOH.

    DOI： 10.1016/j.jjcc.2026.07.013

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  • Enhanced precision of tensor electrocardiography through increased cumulative distribution function resolution: Validation in healthy individuals

    Yayoi Tetsuo Tsukada, Hiroaki Hirayama, Kenji Yodogawa, Hiroshige Murata, Yu-ki Iwasaki, Takeo Fujino, Akihiro Shiozawa, Shingo Tsukada

    2026.6

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    Authorship：Lead author,　Corresponding author  

    DOI： 10.64898/2026.05.31.26354561

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  • Mnemonic of Principles for Effective Specialist-Generalist Conferences: The BRIDGE. Reviewed

    Yohei Kanzawa, Yayoi Tetsuou Tsukada, Kenta Ishibashi, Masataka Ono, Yui Matsushima, Motohiro Shingu, Hideki Saito, Koichi Tamita, Naoto Ishimaru

    Journal of general and family medicine   27 ( 2 )   e70113   2026.3

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  • The Vital Role of General Practitioners in Transitional Care for Adults and Young Adults with Special Health Care Needs: Toward a Functional Role-Sharing Framework Reviewed

    Yayoi Tetsuou Tsukada, Akiyo Kurosawa, Takako Yonemoto, Gen Takagi

    JMA Journal   2026

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

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  • Current Status and Challenges of Hospital General Medicine in Japan: A Survey on Professional Roles, Responsibilities, and Career Satisfaction for the Growth of Hospitalist: Insights from the 2023 Japanese Society of Hospital General Medicine Membership Survey Reviewed

    Takako Yonemoto, Yayoi Tetsuou Tsukada, Masahiro Yasutake

    JOURNAL OF HOSPITAL GENERAL MEDICINE   7 ( 5 )   181 - 189   2025.9

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.60227/jhgmeibun.2025-0008

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  • Sex differences in the burden of multiple long-term conditions among Japanese individuals with heart failure Reviewed International journal

    Shuhei Tara, Yayoi Tetsuou Tsukada, Takuya Nishino, Katsuhito Kato, Takeshi Yamamoto, Mitsunori Maruyama, Eitaro Kodani, Nobuaki Kobayashi, Akihiro Shirakabe, Kuniya Asai

    Open Heart   12 ( 2 )   2025.7

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: Multiple long-term conditions (MLTCs) are common among individuals with heart failure (HF); however, the influence of sex on clinical characteristics and prognosis remains unclear. This study investigated sex-related differences in clinical characteristics and prognosis in individuals with HF and a high MLTC burden. METHODS: We conducted a multicentre retrospective study of 3004 hospitalised patients with HF who survived to discharge. Comorbid chronic conditions were defined using the Charlson Comorbidity Index (CCI), and MLTC burden was quantified using the age-adjusted CCI. Patients were stratified into high (CCI≥6; n=1514) and low (CCI<6; n=1490) MLTC burden groups based on the median age-adjusted CCI, and comparisons were made by sex. The primary outcome was a composite of all-cause death or HF readmission within 1 year. RESULTS: The prevalence of ≥2 comorbid conditions increased with age, peaking before age 85 and declining slightly thereafter. This trend differed by sex, with a steeper age-related increase observed in men. In the high MLTC burden group, females were older, had higher left ventricular ejection fraction and were prescribed fewer medications than men. Dementia and rheumatologic disease were more common in women. Although no significant sex differences in event-free survival were observed overall in either MLTC group, among individuals aged≥75 years with high MLTC burden, men had a significantly higher risk of adverse events than women (HR: 1.334; 95% CI 1.031 to 1.727). A spline-based three-way interaction analysis (age×sex×MLTC burden) demonstrated that male risk exceeded female risk after age 70, only in the high MLTC burden group. CONCLUSION: In individuals with HF and a high MLTC burden, age-dependent sex differences in prognosis were evident. These findings highlight the importance of incorporating age-specific and sex-specific approaches into personalised HF care. TRIAL REGISTRATION NUMBER: UMIN000054854.

    DOI： 10.1136/openhrt-2025-003643

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  • JCS/JCC/JACR/JATS 2024 guideline on cardiovascular practice with consideration for diversity, equity, and inclusion. International journal

    Yayoi Tetsuou Tsukada, Chizuko Aoki-Kamiya, Atsushi Mizuno, Atsuko Nakayama, Tomomi Ide, Rie Aoyama, Junko Honye, Katsuyuki Hoshina, Toshimi Ikegame, Koki Inoue, Yasuko K Bando, Masaharu Kataoka, Naoki Kondo, Koji Maemura, Miyuki Makaya, Naoya Masumori, Asako Mito, Mizuho Miyauchi, Aya Miyazaki, Yukiko Nakano, Yoko M Nakao, Mikiya Nakatsuka, Takeo Nakayama, Yasushi Oginosawa, Nao Ohba, Maki Otsuka, Hiroki Okaniwa, Aya Saito, Kozue Saito, Yasushi Sakata, Mariko Harada-Shiba, Kyoko Soejima, Saeko Takahashi, Tetsuya Takahashi, Toshihiro Tanaka, Yuko Wada, Yoshiko Watanabe, Yuichiro Yano, Masayuki Yoshida, Toru Yoshikawa, Jun Yoshimatsu, Takahiro Abe, Zhehao Dai, Ayaka Endo, Mayumi Fukuda-Doi, Kanako Ito-Hagiwara, Ayako Harima, Kyoko Hirakawa, Kazuya Hosokawa, Gemmei Iizuka, Satoshi Ikeda, Noriko Ishii, Kazuhiro P Izawa, Nobuyuki Kagiyama, Yumi Umeda-Kameyama, Sachiko Kanki, Katsuhito Kato, Aya Komuro, Nao Konagai, Yuto Konishi, Fumie Nishizaki, Satsuki Noma, Togo Norimatsu, Yoshimi Numao, Shogo Oishi, Kimie Okubo, Takashi Ohmori, Yuka Otaki, Tatsuhiro Shibata, Junsuke Shibuya, Mai Shimbo, Reiko Shiomura, Kemmyo Sugiyama, Takahiro Suzuki, Emi Tajima, Ayako Tsukihashi, Haruyo Yasui, Keiko Amano, Shun Kohsaka, Tohru Minamino, Ryozo Nagai, Soko Setoguchi, Keiko Terada, Dai Yumino, Hitonobu Tomoike

    Journal of cardiology   85 ( 6 )   510 - 574   2025.6

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jjcc.2025.03.002

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  • Age-Dependent Sex Differences in the Prevalence and Prognosis of Multimorbid Conditions in Individuals with Heart Failure in Japan

    Shuhei Tara, Yayoi Tetsuou Tsukada, Takuya Nishino, Katsuhito Kato, Takeshi Yamamoto, Mitsunori Maruyama, Eitaro Kodani, Nobuaki Kobayashi, Akihiro Shirakabe, Kuniya Asai

    2025.5

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    Authorship：Corresponding author  

    DOI： 10.1101/2025.05.27.25328463

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  • Rationale, Design, Feasibility, and Profile of the Japanese Circulation Society Chest Pain Registry - Single-Center Pilot Study. Reviewed

    Satoshi Yoshimura, Kanna Arimoto, Hirotoshi Nishikita, Yohei Fushimura, Yasuyuki Sumida, Hirokazu Yokoi, Chika Nishiyama, Takuya Taniguchi, Tetsuya Amano, Tomonori Itoh, Satomi Konno, Nogiku Niwamae, Masashi Sakuma, Kayoko Sato, Yasuhiro Satoh, Yoshio Tahara, Kenichi Tsujita, Yayoi Tetsuou Tsukada, Yasunori Ueda, Takeyuki Kiguchi, Kosuke Kiyohara, Tetsuhisa Kitamura, Taku Iwami

    Circulation journal : official journal of the Japanese Circulation Society   89 ( 11 )   1740 - 1751   2025.5

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    BACKGROUND: Acute coronary syndrome (ACS) requires prompt diagnosis and treatment. Although "OPQRST" (Onset, Provocation, Quality, Region/Radiation, Symptoms, and Time) is commonly used, the evidence linking emergency department (ED) chest pain characteristics to ACS remains inconclusive. This study evaluated detailed symptoms in ED patients with and without ACS using a broad chest pain registry with symptom data. METHODS AND RESULTS: This single-center prospective study was conducted at Rakuwakai-Otowa Hospital in Kyoto, Japan, as a pilot study for a multicenter registry. We enrolled 420 consecutive adult patients presenting with chest pain at the ED from June 2022 to May 2023. Baseline characteristics (including symptoms) and outcomes were recorded. Of the 420 patients, 65 (15.5%) were diagnosed with ACS. Patients with and without ACS differed in the proportion with sudden onset (58.5% vs. 27.6%, respectively), radiation to the tooth (9.2% vs. 0.6%, respectively), and cold sweat (diaphoresis; 44.6% vs. 16.9%, respectively). In the overall population, positive likelihood ratios were 2.12 (95% confidence interval [CI] 1.63-2.76) for sudden onset, 16.38 (95% CI 3.38-79.41) for radiation to the tooth, and 2.64 (95% CI 1.85-3.77) for diaphoresis. CONCLUSIONS: This study in a suburban area of Japan (one of the most super-aged societies) identified key chest pain characteristics in a broad chest pain cohort (i.e., sudden onset, radiation to the tooth, and diaphoresis) that may help with the rapid triage and diagnosis of ACS.

    DOI： 10.1253/circj.CJ-24-0832

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  • JCS/JCC/JACR/JATS 2024 Guideline on Cardiovascular Practice With Consideration for Diversity, Equity, and Inclusion.

    Yayoi Tetsuou Tsukada, Chizuko Aoki-Kamiya, Atsushi Mizuno, Atsuko Nakayama, Tomomi Ide, Rie Aoyama, Junko Honye, Katsuyuki Hoshina, Toshimi Ikegame, Koki Inoue, Yasuko K Bando, Masaharu Kataoka, Naoki Kondo, Koji Maemura, Miyuki Makaya, Naoya Masumori, Asako Mito, Mizuho Miyauchi, Aya Miyazaki, Yukiko Nakano, Yoko M Nakao, Mikiya Nakatsuka, Takeo Nakayama, Yasushi Oginosawa, Nao Ohba, Maki Otsuka, Hiroki Okaniwa, Aya Saito, Kozue Saito, Yasushi Sakata, Mariko Harada-Shiba, Kyoko Soejima, Saeko Takahashi, Tetsuya Takahashi, Toshihiro Tanaka, Yuko Wada, Yoshiko Watanabe, Yuichiro Yano, Masayuki Yoshida, Toru Yoshikawa, Jun Yoshimatsu, Takahiro Abe, Zhehao Dai, Ayaka Endo, Mayumi Fukuda-Doi, Kanako Ito-Hagiwara, Ayako Harima, Kyoko Hirakawa, Kazuya Hosokawa, Gemmei Iizuka, Satoshi Ikeda, Noriko Ishii, Kazuhiro P Izawa, Nobuyuki Kagiyama, Yumi Umeda-Kameyama, Sachiko Kanki, Katsuhito Kato, Aya Komuro, Nao Konagai, Yuto Konishi, Fumie Nishizaki, Satsuki Noma, Togo Norimatsu, Yoshimi Numao, Shogo Oishi, Kimie Okubo, Takashi Ohmori, Yuka Otaki, Tatsuhiro Shibata, Junsuke Shibuya, Mai Shimbo, Reiko Shiomura, Kemmyo Sugiyama, Takahiro Suzuki, Emi Tajima, Ayako Tsukihashi, Haruyo Yasui, Keiko Amano, Shun Kohsaka, Tohru Minamino, Ryozo Nagai, Soko Setoguchi, Keiko Terada, Dai Yumino, Hitonobu Tomoike

    Circulation journal : official journal of the Japanese Circulation Society   89 ( 5 )   658 - 739   2025.4

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1253/circj.CJ-23-0890

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  • Impact of the COVID-19 pandemic on international business travel and associated health issues: a survey of Japanese public companies Reviewed

    Yayoi Tetsuou Tsukada, Ritsuko Okamura, Masahiro Yasutake

    Environmental and Occupational Health Practice   7 ( 1 )   2025

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    UNLABELLED: Background: The globalization of business has significantly increased the number of international business travelers (IBTs), yet their health issues remain inadequately studied. Short-term IBTs, who travel for less than 6 months, lack mandatory health checks under Japanese law, making it difficult to assess their health risks. The COVID-19 pandemic further complicated business travel, highlighting the need for enhanced health management strategies. METHODS: A cross-sectional questionnaire survey was conducted among listed companies in Japan between September and December 2021. The survey targeted general affairs and human resources departments of 3,845 companies, yielding 251 valid responses (6.5% response rate). The questionnaire covered the necessity of business travel, health concerns before and after COVID-19, and expectations for occupational health support. Statistical analyses, including Pearson's chi-square test and text mining, were performed to evaluate trends. RESULTS: Before COVID-19, key health concerns included medical issues during travel (82.2%), infectious disease prevention (69%), and general health management (19.7%). Post-pandemic, priorities shifted to COVID-19 prevention, infectious disease control, and mental health support. Large companies emphasized psychological care, while smaller firms focused on infectious disease management. Business travel remained crucial for 85% of respondents, particularly for on-site guidance and sales. CONCLUSIONS: The pandemic underscored the need for comprehensive health management for IBTs, incorporating infection control, psychological support, and preventive care. As global travel resumes, companies must reassess health strategies to mitigate risks and ensure traveler well-being.

    DOI： 10.1539/eohp.2025-0016

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  • Comprehensive Health Challenges and Management Strategies for International Business Travelers: A Scoping Review Reviewed

    Yayoi Tetsuou Tsukada, Ritsuko Okamura, Masahiro Yasutake

    JMA Journal   8 ( 4 )   1021 - 1030   2025

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Japan Medical Association  

    DOI： 10.31662/jmaj.2025-0085

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  • Strategies for Reducing Sudden Cardiac Death by Raising Public Awareness - A Statement From the Education and Implementation for Cardiac Emergency Committee of the Japanese Circulation Society. Reviewed

    Chika Nishiyama, Satoshi Yoshimura, Takuya Taniguchi, Tetsuya Amano, Hirohiko Ando, Yosuke Homma, Tomohiko Imamura, Tomonori Itoh, Takeyuki Kiguchi, Kosuke Kiyohara, Satomi Konno, Hisaki Makimoto, Tomohiro Manabe, Yasushi Matsuzawa, Hideo Mitamura, Nogiku Niwamae, Masashi Sakuma, Kayoko Sato, Yasuhiro Satoh, Yoshio Tahara, Kenichi Tsujita, Yayoi Tetsuou Tsukada, Masato Uchida, Yasunori Ueda, Taku Iwami

    Circulation journal : official journal of the Japanese Circulation Society   89 ( 3 )   394 - 418   2024.12

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    DOI： 10.1253/circj.CJ-24-0599

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  • Tensor cardiography: A novel ECG analysis of deviations in collective myocardial action potential transitions based on point processes and cumulative distribution functions. Reviewed International journal

    Shingo Tsukada, Yu-Ki Iwasaki, Yayoi Tetsuo Tsukada

    PLOS digital health   3 ( 8 )   e0000273   2024.8

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    Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)  

    To improve clinical diagnoses, assessments of potential cardiac disease risk, and predictions of lethal arrhythmias, the analysis of electrocardiograms (ECGs) requires a more accurate method of weighting waveforms to efficiently detect abnormalities that appear as minute strains in the waveforms. In addition, the inverse problem of estimating the myocardial action potential from the ECG has been a longstanding challenge. To analyze the variance of the ECG waveforms and to estimate collective myocardial action potentials (APs) from the ECG, we designed a model equation incorporating the probability densities of Gaussian functions of time-series point processes in the cardiac cycle and dipoles of the collective APs in the myocardium. The equation, which involves taking the difference between the cumulative distribution functions (CDFs) that represent positive endocardial and negative epicardial potentials, fits both R and T waves. The mean, standard deviation, weights, and level of each cumulative distribution function (CDF) are metrics for the variance of the transition state of the collective myocardial AP. Clinical ECGs of myocardial ischemia during coronary intervention show abnormalities in the aforementioned specific elements of the tensor associated with repolarization transition variance earlier than in conventional indicators of ischemia. The tensor can be used to evaluate the beat-to-beat dynamic repolarization changes between the ventricular epi and endocardium in terms of the Mahalanobis distance (MD). This tensor-based cardiography that uses the differences between CDFs to show changes in collective myocardial APs has the potential to be a new analysis tool for ECGs.

    DOI： 10.1371/journal.pdig.0000273

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  • Sex Differences in Bleeding Risk Associated With Antithrombotic Therapy Following Percutaneous Coronary Intervention Reviewed

    Yoshimi Numao, Saeko Takahashi, Yoko M Nakao, Emi Tajima, Satsuki Noma, Ayaka Endo, Junko Honye, Yayoi Tsukada

    Circulation Reports   6 ( 4 )   99 - 109   2024.3

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    Background: Antithrombotic therapy is crucial for secondary prevention of cardiovascular disease (CVD), but women with CVD may face increased bleeding complications post-percutaneous coronary intervention (PCI) under antithrombotic therapy. However, women are often underrepresented in clinical trials in this field, so evidence for sex-specific recommendations is lacking. Methods and Results: A search on PubMed was conducted for English-language articles addressing bleeding complications and antithrombotic therapy in women. Despite women potentially showing higher baseline platelet responsiveness than men, the clinical implications remain unclear. Concerning antiplatelet therapy post-PCI, although women have an elevated bleeding risk in the acute phase, no sex differences were observed in the chronic phase. However, women require specific considerations for factors such as age, renal function, and weight when determining the dose and duration of antiplatelet therapy. Regarding anticoagulation post-PCI, direct oral anticoagulants may pose a lower bleeding risk in women compared with warfarin. Concerning triple antithrombotic therapy (TAT) post-PCI for patients with atrial fibrillation, there is a lack of evidence on whether sex differences should be considered in the duration and regimen of TAT. Conclusions: Recent findings on sex differences in post-PCI bleeding complications did not provide enough evidence to recommend specific therapies for women. Further studies are needed to address this gap and recommend optimal antithrombotic therapy post-PCI for women.

    DOI： 10.1253/circrep.CR-24-0015

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  • Exploratory Online Survey Regarding Perceptions of Health Inequities Influenced by Social Determinants of Health Among Cardiovascular Disease Patients. Reviewed

    Takahiro Suzuki, Haruyo Yasui, Toshiko Yoshida, Satsuki Noma, Takashi Ohmori, Gemmei Iizuka, Takeo Nakayama, Naoki Kondo, Yayoi Tetsuou Tsukada, Atsushi Mizuno

    International heart journal   65 ( 5 )   881 - 888   2024

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    Despite establishing conventional risk factors and preventive medicine for cardiovascular diseases (CVD), there remains a notable lack of research for identifying social determinants of health (SDOH). The aim of this study was to identify the SDOH domains contributing to health inequities perceived by Japanese CVD citizens. An online survey was conducted among 2,083 Japanese CVD patients from November 7 to 13, 2023, to assess their perceptions of 19 social determinants of health (SDOH) domains and their impact on health inequities. Using the 5-point Likert scale, a high level of agreement was defined as over 50% selecting "Agree" or "Strongly Agree." The "Health inequity perception score (HIPS)" was calculated by assigning 1 point for 'Agree' and 2 points for 'Strongly Agree.' Additionally, patient factors that defined a group with HIPS above the median were also evaluated. High agreement was noted in 7 out of 19 domains: "Employment" (61%), "Food Insecurity" and "Environmental Condition" (each at 60%), "Poverty" (58%), "Early Childhood Development and Education" (57%), "Housing Instability and Quality" (56%), and "Access to Health Service" (52%). Young age, high annual income, high educational level, and living alone were significantly associated with high HIPS. This study highlights that several SDOH factors commonly acknowledged in Western contexts are also recognized as contributors to health inequities among Japanese CVD patients.

    DOI： 10.1536/ihj.24-233

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  • Scoping Review of Screening and Assessment Tools for Social Determinants of Health in the Field of Cardiovascular Disease. Reviewed

    Takahiro Suzuki, Atsushi Mizuno, Haruyo Yasui, Satsuki Noma, Takashi Ohmori, Jeffrey Rewley, Fujimi Kawai, Takeo Nakayama, Naoki Kondo, Yayoi Tetsuou Tsukada

    Circulation journal : official journal of the Japanese Circulation Society   88 ( 3 )   390 - 407   2023.12

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    BACKGROUND: Despite the importance of implementing the concept of social determinants of health (SDOH) in the clinical practice of cardiovascular disease (CVD), the tools available to assess SDOH have not been systematically investigated. We conducted a scoping review for tools to assess SDOH and comprehensively evaluated how these tools could be applied in the field of CVD.Methods and Results: We conducted a systematic literature search of PubMed and Embase databases on July 25, 2023. Studies that evaluated an SDOH screening tool with CVD as an outcome or those that explicitly sampled or included participants based on their having CVD were eligible for inclusion. In addition, studies had to have focused on at least one SDOH domain defined by Healthy People 2030. After screening 1984 articles, 58 articles that evaluated 41 distinct screening tools were selected. Of the 58 articles, 39 (67.2%) targeted populations with CVD, whereas 16 (27.6%) evaluated CVD outcome in non-CVD populations. Three (5.2%) compared SDOH differences between CVD and non-CVD populations. Of 41 screening tools, 24 evaluated multiple SDOH domains and 17 evaluated only 1 domain. CONCLUSIONS: Our review revealed recent interest in SDOH in the field of CVD, with many useful screening tools that can evaluate SDOH. Future studies are needed to clarify the importance of the intervention in SDOH regarding CVD.

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  • APPLICATION OF A NOVEL ECG ANALYSIS, TENSOR CARDIOGRAPHY (TCG) TO THE DIAGNOSIS OF MYOCARDIAL ISCHEMIA - A CASE REPORT Reviewed

    Shingo Tsukada, Yu-Ki Iwasaki, Yayoi Tetsuou Tsukada, Hiroshige Murata

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   81 ( 8 )   157 - 157   2023.3

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  • Effect of Empagliflozin Versus Placebo on Body Fluid Balance in Patients With Acute Myocardial Infarction and Type 2 Diabetes Mellitus: Subgroup Analysis of the EMBODY Trial Reviewed International journal

    Yu Hoshika, Yoshiaki Kubota, Kosuke Mozawa, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu Ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Mitsunori Maruyama, Jun Tanabe, Wataru Shimizu

    Journal of Cardiac Failure   28 ( 1 )   56 - 64   2022.1

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    Background: The development of heart failure is associated with fluid balance, including that of extracellular water (ECW) and intracellular water (ICW). This study determined whether sodium–glucose cotransporter 2 inhibitors affect fluid balance and improve heart failure in patients after acute myocardial infarction. Methods and Results: EMBODY was a prospective, randomized, double-blinded, placebo-controlled trial of Japanese patients with acute myocardial infarction and type 2 diabetes. Overall, 55 patients who underwent bioelectrical impedance analysis were randomized to receive once daily 10 mg empagliflozin or placebo 2 weeks after acute myocardial infarction onset. We investigated the time course of body fluid balance measured using the bioelectrical impedance analysis device, InBody. The primary end points were changes in body fluid balance from weeks 0 to 24. Changes between baseline and week 24 in the empagliflozin and placebo groups were –0.21 L (P = .127) and +0.40 L (P = .001) in ECW (P = .001) and –0.23 L (P = .264) and +0.74 L (P < .001) in ICW (P < .001), respectively. In a stratified analysis, the rise in ECW and ICW was significantly attenuated in the empagliflozin group in contrast to the placebo group in participants with a body mass index of 25 or higher but not in those with a body mass index of less than 25. Conclusions: Early sodium–glucose cotransporter 2 inhibitor administration may attenuate changes in ECW and ICW.

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  • Awareness and Feasibility of Women Chairing Cardiology Sessions in Scientific Meetings: A Nationwide Survey by the Japanese Circulation Society. Reviewed International journal

    Atsuko Nakayama, Chizuko A Kamiya, Sachiko Kanki, Tomomi Ide, Yasuko K Bando, Yukari Uemura, Yayoi Tetsuou Tsukada

    Frontiers in cardiovascular medicine   9   871546 - 871546   2022

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    Background: Diversity and inclusion remain a concern in the field of cardiology. Female cardiologists have less opportunity to chair sessions in scientific meetings than men. However, cardiologists' awareness and perspectives on feasibility of chairing sessions is poorly understood. Methods and Results: A web-based survey on awareness regarding the commitment of chairing sessions was sent to 14,798 certificated cardiologists registered with the Japanese Circulation Society (JCS). A total of 3,412 valid responses were obtained, such as 523 women and 2,889 men. Female cardiologists exhibited less interest in serving as chairpersons in Japanese and English sessions (71% women vs. 82% men, p < 0.001, 30% women vs. 40% men, p < 0.001). Influencing factors of chair acceptance in Japanese sessions for female cardiologists were being a cardiologist for over 10 years [odds ratio (OR) 1.84, 95% confidence interval (CI) 1.02-3.33], experience studying abroad (OR 3.35, 95% CI 1.93-5.81) and chairing sessions (OR 8.39, 95% CI 5.48-12.9), having a Doctor of Philosophy (OR 2.82, 95% CI 1.09-7.31), presence of 4 or more female cardiovascular specialists in the hospital (OR 1.70, 95% CI 1.10-2.61) and of role models (OR 2.86, 95% CI 1.93-4.24), and awareness of the JCS chairperson's manual (OR 10.7, 95% CI 6.67-17.1). The receiver operating characteristic (ROC) curve revealed that the number of female cardiovascular specialists in a hospital was a more sensitive predictor of chair acceptance among male than female cardiologists. Conclusions: Female cardiologists were less likely to accept chairing sessions compared with male cardiologists and the presence of female cardiovascular specialists positively influenced chair acceptance.

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  • Empagliflozin confers reno-protection in acute myocardial infarction and type 2 diabetes mellitus Reviewed International journal

    Kosuke Mozawa, Yoshiaki Kubota, Yu Hoshika, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Mitsunori Maruyama, Jun Tanabe, Wataru Shimizu

    ESC Heart Failure   8 ( 5 )   4161 - 4173   2021.10

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    AIMS: Although the reno-protective effects of sodium-glucose cotransporter 2 inhibitors are known in patients with heart failure or type 2 diabetes mellitus (T2DM), this effect has not been confirmed in patients with acute myocardial infarction (AMI). METHODS AND RESULTS: The prospective, multicentre, randomized, double-blind, placebo-controlled EMBODY trial investigated patients with AMI and T2DM in Japan. The eligible patients included adults aged 20 years or older, diagnosed with AMI and T2DM, and who could be discharged within 2-12 weeks after the onset of AMI. One hundred and five patients were randomized (1:1) to receive once daily 10 mg empagliflozin or placebo within 2 weeks of AMI onset. In this sub-analysis, we investigated the time course of renal functional parameters such as serum creatinine levels and estimated glomerular filtration rate (eGFR) from baseline to Weeks 4, 12, and 24. Ninety-six patients (64 ± 11 years, 78 male) were included in the full analysis (n = 46 and 50 in the empagliflozin and placebo groups, respectively). We used serum creatinine and eGFR as indicators of renal function. In the placebo group, eGFR decreased from 66.14 mL/min/1.73 m2 at baseline to 62.77 mL/min/1.73 m2 by Week 24 (P = 0.023) but remained unchanged in the empagliflozin group (from 64.60 to 64.36 mL/min/1.73 m2 , P = 0.843). In the latter group, uric acid improved from 5.8 mg/dL at baseline to 4.9 mg/dL at Week 24 (P < 0.001). In the earlier analysis of 56 patients with eGFR ≥ 60 mL/min/1.73 m2 , the eGFR decreased and the serum creatinine increased from baseline to 24 weeks in the placebo group, significantly different to the empagliflozin group (-6.61 vs. +0.22 mL/min/1.73 m2 , P = 0.008 and +0.063 vs. -0.001 mg/dL, P = 0.030, respectively). The changes in serum creatinine and eGFR from baseline to Week 24 were significantly correlated with those in uric acid in the placebo group (r = 0.664, P < 0.001 and r = -0.675, P < 0.001, respectively) but not in the empagliflozin group. CONCLUSIONS: Empagliflozin prevented the kidney functional decline in patients with AMI and T2DM, especially those with baseline eGFR ≥ 60 mL/min/1.73 m2 . Early administration of sodium-glucose cotransporter 2 inhibitors in these patients is considered desirable for renal protection.

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  • Effect of Empagliflozin Versus Placebo on Plasma Volume Status in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus Reviewed International journal

    Yu Hoshika, Yoshiaki Kubota, Kosuke Mozawa, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Mitsunori Maruyama, Jun Tanabe, Wataru Shimizu

    Diabetes Therapy   12 ( 8 )   2241 - 2248   2021.8

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    INTRODUCTION: Plasma volume status (PVS), a parameter of the discrepancy between actual plasma volume (PV) and ideal PV, has been recently evaluated as a prognostic marker in patients with heart failure. This subgroup analysis of the EMBODY trial was designed to determine whether a sodium-glucose cotransporter 2 (SGLT2) inhibitor affects the alleviation of heart failure and improvement of PVS in patients after acute myocardial infarction (AMI) with congestive heart failure (CHF). METHODS: The EMBODY trial was a prospective, multicenter, randomized, double-blind, placebo-controlled trial to identify the effect of an SGLT2 inhibitor on cardiac sympathetic hyperactivity in patients with AMI and type 2 diabetes mellitus (T2DM) in Japan. In total, 105 patients were randomized (1:1) to receive 10 mg empagliflozin or a placebo (once daily), 2 weeks after the onset of AMI. In this subanalysis, we investigated the time-course of PVS at baseline and weeks 4, 12, and 24. RESULTS: Overall, 96 patients were included in the subgroup analysis set (age 64.3 ± 10.9 years, 80.2% men; 46 in the empagliflozin group and 50 in the placebo group). Body weight and PVS decreased in the empagliflozin group compared with the placebo group at 24 weeks (- 2.2 vs. + 0.1 kg, P < 0.001, and - 5.1 vs. - 0.3%, P < 0.001, respectively). Decreased PVS, defined as a change in PVS of < - 4.5%, was associated with the administration of empagliflozin (odds ratio 2.61, 95% confidence interval 1.11-6.15, P = 0.028). N-terminal pro b-type natriuretic peptide levels decreased in both the empagliflozin and placebo groups (1028.7-370.3 pg/mL, P < 0.001, and 1270.6-673.7 pg/mL, P < 0.01, respectively). CONCLUSION: Empagliflozin reduced the body weight and PVS. Early SGLT2 inhibitor administration in patients with AMI, CHF, and T2DM can therefore be effective in reducing the body weight and PVS. TRIAL REGISTRATION: UMIN 000030158.

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  • Status of Medical Care and Management Requirements of Elderly Patients With Heart Failure in a Comprehensive Community Health System ― Survey of General Practitioners’ Views ― Reviewed

    Yayoi Tetsuou Tsukada, Eitaro Kodani, Kuniya Asai, Masahiro Yasutake, Yoshihiko Seino, Wataru Shimizu

    Circulation Reports   inpress ( 2 )   77 - 85   2021.1

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    Background: Given the high prevalence of heart failure (HF) in the elderly, it is essential to establish medical coordination between general practitioners (GPs) and acute care hospitals (ACHs) in an aging society. The aim of this study was to elucidate the status of acceptance of elderly patients with HF and their management requirements in a comprehensive community health system. Furthermore, we investigated GPs' interest in using information and communications technology (ICT) in patient care. Methods and Results: We sent a questionnaire survey to 1,800 GPs in January 2015 and received 392 replies. The overall prevalence of home visits was 55%, with no differences according to GP background characteristics or geographic area. However, less than half (44%) reported accepting patients with symptomatic HF for treatment in their clinic. In addition, only 3 GPs reported accepting and providing emergency visits for patients with refractory HF. In particular, GPs who were not certificated cardiologists, female, and older showed poorer acceptance of symptomatic HF patients. More than half the GPs wanted the prompt acceptance by ACHs of emergency patients, followed by strengthening of home care support at discharge and support for end-of-life care. Half the GPs were interested in telemedicine. Conclusions: ACHs must promptly accept patients with HF in cases of emergency and strengthen nursing care support at discharge. It is also necessary to consider how to support older and female GPs.

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  • Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: The EMBODY trial Reviewed International journal

    Wataru Shimizu, Yoshiaki Kubota, Yu Hoshika, Kosuke Mozawa, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu Ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Masahiro Ishikawa, Mitsunori Maruyama, Michio Ogano, Jun Tanabe, Reiko Shiomura, Isamu Fukuizumi, Junya Matsuda, Satsuki Noma, Hideto Sangen, Hidenori Komiyama, Yoichi Imori, Shunichi Nakamura, Jun Nakata, Hideki Miyachi, Gen Takagi, Takahiro Todoroki, Takeshi Ikeda, Tomoyo Miyakuni, Ayaka Shima, Masato Matsushita, Hirotake Okazaki, Akihiro Shirakabe, Nobuaki Kobayashi, Masamitsu Takano, Yoshihiko Seino, Yugo Nishi, Keishi Suzuki, Junsuke Shibuya, Tsunenori Saito, Hiroyuki Nakano, Morisawa Taichirou, Erito Furuse, Kenji Nakama, Yusuke Hosokawa, Ippei Tsuboi, Hidekazu Kawanaka

    Cardiovascular Diabetology   19 ( 1 )   148 - 148   2020.9

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    BACKGROUND: Protection from lethal ventricular arrhythmias leading to sudden cardiac death (SCD) is a crucial challenge after acute myocardial infarction (AMI). Cardiac sympathetic and parasympathetic activity can be noninvasively assessed using heart rate variability (HRV) and heart rate turbulence (HRT). The EMBODY trial was designed to determine whether the Sodium-glucose cotransporter 2 (SGLT2) inhibitor improves cardiac nerve activity. METHODS: This prospective, multicenter, randomized, double-blind, placebo-controlled trial included patients with AMI and type 2 diabetes mellitus (T2DM) in Japan; 105 patients were randomized (1:1) to receive once-daily 10-mg empagliflozin or placebo. The primary endpoints were changes in HRV, e.g., the standard deviation of all 5-min mean normal RR intervals (SDANN) and the low-frequency-to-high-frequency (LF/HF) ratio from baseline to 24 weeks. Secondary endpoints were changes in other sudden cardiac death (SCD) surrogate markers such as HRT. RESULTS: Overall, 96 patients were included (46, empagliflozin group; 50, placebo group). The changes in SDANN were + 11.6 and + 9.1 ms in the empagliflozin (P = 0.02) and placebo groups (P = 0.06), respectively. Change in LF/HF ratio was - 0.57 and - 0.17 in the empagliflozin (P = 0.01) and placebo groups (P = 0.43), respectively. Significant improvement was noted in HRT only in the empagliflozin group (P = 0.01). Whereas intergroup comparison on HRV and HRT showed no significant difference between the empagliflozin and placebo groups. Compared with the placebo group, the empagliflozin group showed significant decreases in body weight, systolic blood pressure, and uric acid. In the empagliflozin group, no adverse events were observed. CONCLUSIONS: This is the first randomized clinical data to evaluate the effect of empagliflozin on cardiac sympathetic and parasympathetic activity in patients with T2DM and AMI. Early SGLT2 inhibitor administration in AMI patients with T2DM might be effective in improving cardiac nerve activity without any adverse events. TRIAL REGISTRATION: The EMBODY trial was registered by the UMIN in November 2017 (ID: 000030158). UMIN000030158; https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000034442 .

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  • Work-life balance for surgeons: medical education and training to reduce conflict Reviewed

    Junko Umihara, Mariko Nishikitani, Yoshiaki Hayasaka, Terumichi Fujikura, Miho Maeda, Yayoi Tetsuou Tsukada

    Japanese Journal of Rhinology   59 ( 4 )   325 - 334   2020

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  • Validation of wearable textile electrodes for ECG monitoring Reviewed

    Yayoi Tetsuou Tsukada, Miwa Tokita, Hiroshige Murata, Yasuhiro Hirasawa, Kenji Yodogawa, Yu-ki Iwasaki, Kuniya Asai, Wataru Shimizu, Nahoko Kasai, Hiroshi Nakashima, Shingo Tsukada

    Heart and Vessels   34 ( 7 )   1203 - 1211   2019.1

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    A highly conductive textile was woven from nano-fibers coated with the PEDOT-PSS polymer. The aim of this study was to assess the usefulness of textile electrodes for ECG recording as a smart garment. Electrode textile pads and lead wires were sewn to the lining of sportswear and their tolerability to repeated washings were tested up to 150 times. The electrical conductivity of the textile electrode remained functional for up to 50 machine washes. To assess the level of motion artifacts or noise during the daily monitoring of ECG, a single lead ECG with conventional or textile electrodes was recorded during supine rest, seated rest, upright trunk rotation (i.e., twisting), and stepping movement in 66 healthy adults. A Holter system was used for data storage and analysis. ECG patterns of P, QRS, and T waves were comparable between the conventional and textile electrodes. However, the signal-to-artifact-and/or-noise ratio (SAR) during twisting was larger in the textile electrodes than in the conventional electrodes. No skin irritation was seen in the textile electrodes. The single lead textile electrodes embedded in an inner garment were usable for continuous and/or repeated ECG monitoring in daily life except during vigorous trunk movement.

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  • Effect of Empagliflozin Versus Placebo on Cardiac Sympathetic Activity in Acute Myocardial Infarction Patients with Type 2 Diabetes Mellitus: Rationale Reviewed International journal

    Yoshiaki Kubota, Takeshi Yamamoto, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yuki Iwasaki, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Naoki Sato, Jun Tanabe, Wataru Shimizu

    Diabetes Therapy   9 ( 5 )   2107 - 2116   2018.10

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    INTRODUCTION: Protection from lethal ventricular arrhythmias leading to sudden cardiac death is one of the most important problems after myocardial infarction. Cardiac sympathetic hyperactivity is related to poor prognosis and fatal arrhythmias and can be non-invasively assessed with heart rate variability, heart rate turbulence, T-wave alternans, late potentials, and 123I-meta-iodobenzylguanide (123I-MIBG) scintigraphy. Sodium glucose cotransporter 2 (SGLT2) inhibitors potentially reduce sympathetic nervous system activity that is augmented in part due to the stimulatory effect of hyperglycemia. The EMBODY trial is designed to determine whether the suppression of cardiac sympathetic activity induced by the SGLT2 inhibitor is accompanied by protection against adverse cardiovascular outcomes. METHODS: The EMBODY trial is a prospective, multicenter, randomized, double-blind, placebo-controlled trial in patients with acute MI and type 2 diabetes in Japan. A total of 98 patients will be randomized (1:1) to receive once-daily placebo or empagliflozin, an SGLT2 inhibitor, 10 mg. The primary end point is the change from baseline to 24 weeks in heart rate variability. Secondary end points include the change from baseline for other sudden cardiac death surrogate-markers such as heart rate turbulence, T-wave alternans, late potentials, and 123I-MIBG scintigraphy imaging. Adverse effects will be evaluated throughout the trial period. PLANNED OUTCOMES: The EMBODY trial will evaluate the potential cardioprotective effect of empagliflozin and will provide additional important new data regarding its preventative effects on sudden cardiac death. TRIAL REGISTRATION: Unique Trial Number, UMIN000030158 ( https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000034442 ). FUNDING: Nippon Boehringer Ingelheim and Eli Lilly and Company.

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  • Extracellular volume fraction assessed using cardiovascular magnetic resonance can predict improvement in left ventricular ejection fraction in patients with dilated cardiomyopathy. Reviewed

    Keisuke Inui, Kuniya Asai, Masaki Tachi, Aya Yoshinaga, Yuki Izumi, Yoshiaki Kubota, Koji Murai, Yayoi Tetsuou Tsukada, Yasuo Amano, Shinichiro Kumita, Wataru Shimizu

    Heart and vessels   33 ( 10 )   1195 - 1203   2018.10

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    T1 mapping using cardiac magnetic resonance (CMR) is useful for myocardial assessment. However, its prognostic value is not well defined. The aim of this study was to determine whether T1 mapping with CMR can predict reverse cardiac remodeling in patients with non-ischemic dilated cardiomyopathy (NIDCM). We also investigated the predictive prognostic value of T1 mapping with CMR in these patients. We included 33 patients with NIDCM admitted to Nippon Medical School Hospital between February 2012 and October 2015. All patients underwent CMR and echocardiography for clinical assessment within 1 month of admission (13 ± 16 days). Follow-up echocardiography was performed no sooner than 6 months after the initial echocardiogram (536 ± 304 days). We evaluated the correlations between native and post-contrast T1 values/extracellular volume fraction (ECV) and the difference in left ventricular ejection fraction (ΔLVEF) determined at baseline and follow-up echocardiography. No correlation was noted between ΔLVEF and native (p = 0.150, r = - 0.256) or post-contrast T1 values (p = 0.956, r = - 0.010). However, a significant and substantial correlation was found between ΔLVEF and ECV (p = 0.043, r = - 0.355). Four patients were hospitalized for heart failure (HF), but no cardiovascular-related deaths occurred over a median follow-up period of 34 months (interquartile range 25-49 months). Kaplan-Meier curves stratified by the median value of ECV were created. The higher ECV groups experienced a significantly higher incidence of HF-related hospitalization (p = 0.0159). ECV measured by CMR can predict improvements in LVEF in patients with NIDCM. In addition, ECV may be a predictive factor for HF-related hospitalization.

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    Other Link： https://search.jamas.or.jp/default/link?pub_year=2018&ichushi_jid=J04638&link_issn=&doc_id=20180927140009&doc_link_id=10.1007%2Fs00380-018-1154-0&url=https%3A%2F%2Fdoi.org%2F10.1007%2Fs00380-018-1154-0&type=Crossref&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00002_2.gif

  • COPD advances in left ventricular diastolic dysfunction Reviewed International journal

    Yoshiaki Kubota, Kuniya Asai, Koji Murai, Yayoi Tetsuou Tsukada, Hiroki Hayashi, Yoshinobu Saito, Arata Azuma, Akihiko Gemma, Wataru Shimizu

    International Journal of COPD   11 ( 1 )   649 - 655   2016.3

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    Background: COPD is concomitantly present in ~30% of patients with heart failure. Here, we investigated the pulmonary function test parameters for left ventricular (LV) diastolic dysfunction and the relationship between pulmonary function and LV diastolic function in patients with COPD. Patients and methods: Overall, 822 patients who underwent a pulmonary function test and echocardiography simultaneously between January 2011 and December 2012 were evaluated. Finally, 115 patients with COPD and 115 age- and sex-matched control patients with an LV ejection fraction of ≥50% were enrolled. Results: The mean age of the patients was 74.4±10.4 years, and 72.3% were men. No significant differences were found between the two groups regarding comorbidities, such as hypertension, diabetes mellitus, and anemia. The index of LV diastolic function (E/e') and the proportion of patients with high E/e' (defined as E/e' ≥ 15) were significantly higher in patients with COPD than in control patients (10.5% vs 9.1%, P=0.009
    11.3% vs 4.3%, P=0.046). E/e' was significantly correlated with the residual volume/total lung capacity ratio. Univariate and multivariate analyses revealed severe COPD (Global Initiative for Chronic Obstructive Lung Disease III or IV) to be a significant predictive factor for high E/e' (odds ratio [OR] 5.81, 95% confidence interval [CI] 2.13-15.89, P=0.001 and OR 6.00, 95% CI 2.08-17.35, P=0.001, respectively). Conclusion: Our data suggest that LV diastolic dysfunction as a complication of COPD may be associated with mechanical exclusion of the heart by pulmonary overinflation.

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  • 導電性高分子(PEDOT-PSS)繊維によるシャツ型生体電極(hitoe)を用いたホルター心電図検査使用経験

    塚田 弥生, 哲翁, 村田 広茂, 淀川 顕司, 清水 渉, 河西 奈保子, 住友 弘二, 塚田 信吾

    心電図   36 ( Suppl.1 )   S - 1   2016.2

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  • Impact of sleep-disordered breathing and efficacy of positive airway pressure on mortality in patients with chronic heart failure and sleep-disordered breathing: a meta-analysis. Reviewed International journal

    Shunichi Nakamura, Kuniya Asai, Yoshiaki Kubota, Koji Murai, Hitoshi Takano, Yayoi Tetsuou Tsukada, Wataru Shimizu

    Clinical research in cardiology : official journal of the German Cardiac Society   104 ( 3 )   208 - 16   2015.3

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    BACKGROUNDS: To conduct a meta-analysis to investigate whether sleep-disordered breathing (SDB) is an independent risk factor for mortality and whether positive airway pressure (PAP) decreases mortality in patients with chronic heart failure (HF). The impact of SDB and the effects of PAP on mortality in patients with chronic HF remain unclear. METHODS: We searched the MEDLINE, EMBASE, and Cochrane databases. Clinical trials that addressed mortality and the effect of PAP on mortality in chronic HF patients with SDB were included in this meta-analysis. RESULTS: Eleven studies (1,944 participants in total) that addressed mortality in chronic HF patients with SDB were included in this study. Patients with SDB showed a significantly increased mortality risk compared to those without SDB [risk ratio (RR) 1.66 (1.19-2.31)]. In sub-analyses, a significant increase in risk of mortality was observed for central sleep apnea versus no-SDB [RR 1.48 (1.15-1.91)], whereas no significant increase in risk was observed for obstructive sleep apnea versus no-SDB. Five randomized controlled studies (395 participants) that assessed the effect of PAP in chronic HF patients with SDB were analyzed. Adaptive servo-ventilation (ASV) significantly reduced all-cause mortality in chronic HF patients with SDB [RR 0.13 (0.02-0.95)], whereas continuous PAP did not significantly reduce all-cause mortality [RR 0.71 (0.32-1.57)]. CONCLUSIONS: The prevalence of SDB in patients with chronic HF is associated with worse survival, and ASV reduces all-cause mortality in patients with chronic HF concomitant with SDB.

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  • Impact of beta-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease Reviewed

    Yoshiaki Kubota, Kuniya Asai, Erito Furuse, Shunichi Nakamura, Koji Murai, Yayoi Tetsuou Tsukada, Wataru Shimizu

    INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE   10   515 - 523   2015

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    Background: Chronic obstructive pulmonary disease (COPD) is present in approximately one-third of all congestive heart failure (CHF) patients, and is a key cause of underprescription and underdosing of beta-blockers, largely owing to concerns about precipitating respiratory deterioration. For these reasons, the aim of this study was to evaluate the impact of beta-blockers on the long-term outcomes in CHF patients with COPD. In addition, we compared the effects of two different beta-blockers, carvedilol and bisoprolol.
    Methods: The study was a retrospective, non-randomized, single center trial. Acute decompensated HF patients with COPD were classified according to the oral drug used at discharge into beta-blocker (n=86; carvedilol [n=52] or bisoprolol [n=34]) and non-beta-blocker groups (n=46). The primary endpoint was all-cause mortality between the beta-blocker and non-beta-blocker groups during a mean clinical follow-up of 33.9 months. The secondary endpoints were the differences in all-cause mortality and the hospitalization rates for CHF and/or COPD exacerbation between patients receiving carvedilol and bisoprolol.
    Results: The mortality rate was higher in patients without beta-blockers compared with those taking beta-blockers (log-rank P=0.039), and univariate analyses revealed that the use of beta-blockers was the only factor significantly correlated with the mortality rate (hazard ratio: 0.41; 95% confidence interval: 0.17-0.99; P=0.047). Moreover, the rate of CHF and/or COPD exacerbation was higher in patients treated with carvedilol compared with bisoprolol (log-rank P=0.033). In the multivariate analysis, only a past history of COPD exacerbation significantly increased the risk of re-hospitalization due to CHF and/or COPD exacerbation (adjusted hazard ratio: 3.11; 95% confidence interval: 1.47-6.61; P=0.003).
    Conclusion: These findings support the recommendations to use beta-blockers in HF patients with COPD. Importantly, bisoprolol reduced the incidence of CHF and/or COPD exacerbation compared with carvedilol.

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  • Impact of β-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease. Reviewed International journal

    Yoshiaki Kubota, Kuniya Asai, Erito Furuse, Shunichi Nakamura, Koji Murai, Yayoi Tetsuou Tsukada, Wataru Shimizu

    International journal of chronic obstructive pulmonary disease   10   515 - 23   2015

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    BACKGROUND: Chronic obstructive pulmonary disease (COPD) is present in approximately one-third of all congestive heart failure (CHF) patients, and is a key cause of underprescription and underdosing of β-blockers, largely owing to concerns about precipitating respiratory deterioration. For these reasons, the aim of this study was to evaluate the impact of β-blockers on the long-term outcomes in CHF patients with COPD. In addition, we compared the effects of two different β-blockers, carvedilol and bisoprolol. METHODS: The study was a retrospective, non-randomized, single center trial. Acute decompensated HF patients with COPD were classified according to the oral drug used at discharge into β-blocker (n=86; carvedilol [n=52] or bisoprolol [n=34]) and non-β-blocker groups (n=46). The primary endpoint was all-cause mortality between the β-blocker and non-β-blocker groups during a mean clinical follow-up of 33.9 months. The secondary endpoints were the differences in all-cause mortality and the hospitalization rates for CHF and/or COPD exacerbation between patients receiving carvedilol and bisoprolol. RESULTS: The mortality rate was higher in patients without β-blockers compared with those taking β-blockers (log-rank P=0.039), and univariate analyses revealed that the use of β-blockers was the only factor significantly correlated with the mortality rate (hazard ratio: 0.41; 95% confidence interval: 0.17-0.99; P=0.047). Moreover, the rate of CHF and/or COPD exacerbation was higher in patients treated with carvedilol compared with bisoprolol (log-rank P=0.033). In the multivariate analysis, only a past history of COPD exacerbation significantly increased the risk of re-hospitalization due to CHF and/or COPD exacerbation (adjusted hazard ratio: 3.11; 95% confidence interval: 1.47-6.61; P=0.003). CONCLUSION: These findings support the recommendations to use β-blockers in HF patients with COPD. Importantly, bisoprolol reduced the incidence of CHF and/or COPD exacerbation compared with carvedilol.

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  • Importance of Peak Uric Acid in Patients with Acute Heart Failure Syndromes Reviewed

    Koji Murai, Kuniya Asai, Eichiro Oka, Yoshiaki Kubota, Syunichi Nakamura, Keisuke Inui, Masatomo Yoshikawa, Yayoi Tsukada, Naoki Sato, Wataru Shimizu

    JOURNAL OF CARDIAC FAILURE   20 ( 10 )   S181 - S181   2014.10

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  • [Adverse effects of cardiovascular agents in Japan--update 2012]. Reviewed

    Tsukada YT

    Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 6   239 - 244   2012.8

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  • Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole. Reviewed International journal

    Chengqun Huang, Wayne Liu, Cynthia N Perry, Smadar Yitzhaki, Youngil Lee, Hua Yuan, Yayoi Tetsuo Tsukada, Anne Hamacher-Brady, Robert M Mentzer Jr, Roberta A Gottlieb

    American journal of physiology. Heart and circulatory physiology   298 ( 2 )   H570-9 - H579   2010.2

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    Previously, we showed that sulfaphenazole (SUL), an antimicrobial agent that is a potent inhibitor of cytochrome P4502C9, is protective against ischemia-reperfusion (I/R) injury (Ref. 15). The mechanism, however, underlying this cardioprotection, is largely unknown. With evidence that activation of autophagy is protective against simulated I/R in HL-1 cells, and evidence that autophagy is upregulated in preconditioned hearts, we hypothesized that SUL-mediated cardioprotection might resemble ischemic preconditioning with respect to activation of protein kinase C and autophagy. We used the Langendorff model of global ischemia to assess the role of autophagy and protein kinase C in myocardial protection by SUL during I/R. We show that SUL enhanced recovery of function, reduced creatine kinase release, decreased infarct size, and induced autophagy. SUL also triggered PKC translocation, whereas inhibition of PKC with chelerythrine blocked the activation of autophagy in adult rat cardiomyocytes. In the Langendorff model, chelerythrine suppressed autophagy and abolished the protection mediated by SUL. SUL increased autophagy in adult rat cardiomyocytes infected with GFP-LC3 adenovirus, in isolated perfused rat hearts, and in mCherry-LC3 transgenic mice. To establish the role of autophagy in cardioprotection, we used the cell-permeable dominant-negative inhibitor of autophagy, Tat-Atg5(K130R). Autophagy and cardioprotection were abolished in rat hearts perfused with recombinant Tat-Atg5(K130R). Taken together, these studies indicate that cardioprotection mediated by SUL involves a PKC-dependent induction of autophagy. The findings suggest that autophagy may be a fundamental process that enhances the heart's tolerance to ischemia.

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  • Solutions for Retention of Female Cardiologists From the Survey of Gender Differences in the Work and Life of Cardiologists - Reviewed

    Yayoi Tetsuou Tsukada, Miwa Tokita, Kazuyo Kato, Yuko Kato, Mizuho Miyauchi, Isuzu Ono, Hiroko Tanabe, Tomoko Yokoshima, Hiroko Fukumoto, Yoshiko Miyatake, Kyoichi Mizuno

    CIRCULATION JOURNAL   73 ( 11 )   2076 - 2083   2009.11

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    Background: To present a future shortage of cardiologists, it is important for female Cardiologists to continue working. Gender differences in the professional and private lives of cardiologists. as well as the barriers to work for female cardiologists. were surveyed
    Methods and Results: In August 2007. a questionnaire was mailed to all 195 facility members/fellows and 155 alumni of the Department of Cardiovascular Medicine at Nippon Medical School. More female cardiologists job than male cardiologists (34% vs 17%, P&lt;0.005). Women reported greater career were dissatisfied with their limitation by family responsibilities and housework Men and women both reported that long working hours was the most problematic issue, but significantly more women reported this than men (76% vs 94%, P&lt;0.05). Female cardiologists were more concerned about occupational radiation exposure (88% vs 59%, P&lt;0.01) and wanted opportunities for retraining after childcare leave (100% vs 76%, P&lt;0.01).
    Conclusions: The following measures should be taken: (1) establishment of more family-friendly working conditions in hospitals, (2) provision of various work positions that allow more flexibility and predictability for women, (3) establishment of a retraining system. and (4) development of work and research opportunities that are attractive to women. The Japanese Circulation Society is expected to establish a retraining system at certified institutions. (Circ J 2009: 73: 2076-2083)

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  • S1P1-selective agonist SEW2871 exacerbates reperfusion arrhythmias Reviewed

    Yayoi T. Tsukada, M. Germana Sanna, Hugh Rosen, Roberta A. Gottlieb

    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY   50 ( 6 )   660 - 669   2007.12

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    Sphingosine-1-phosphate (S1P) has been considered to play an important role in ischemia/reperfusion (LR) injury. We used SEW2871 (SEW), a novel receptor-selective agonist for S1P1, to elucidate the role of SIPI in myocardial I/R. Isolated perfused rat hearts exposed to S1P (1 and 10 mM) or SEW (1 and 0.1 mM) were subjected to 30 minutes of global no-flow ischemia and 2 hours of repertusion. S1P at 1 and 10 mM significantly reduced infarct size and CK release compared with vehicle-control. The effect of 0.1 mu M SEW on infarct size was modest. After I/R, S1P at both doses and SEW at 0.1 mu M improved developed pressure (LVDP). SEW at 1 mM significantly prolonged the duration of ventricular tachycardia and ventricular fibrillation, leading to irreversible reperfusion tachyar-rhythmias in 60% of the hearts. This is the first demonstration of the critical role of the S1P1 receptor in I/R injury.

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  • Real-time measurement of nitric oxide by luminol-hydrogen peroxide reaction in crystalloid perfused rat heart Reviewed International journal

    Y Tsukada, M Yasutake, DL Jia, Y Kusama, H Kishida, T Takano, S Tsukada

    LIFE SCIENCES   72 ( 9 )   989 - 1000   2003.1

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    The objective of this study was to develop an assay system that allows continuous monitoring of nitric oxide (NO) released from crystalloid perfused hearts. We utilized chemiluminescence reaction between NO and luminol-H2O2 to quantify the NO level in coronary effluent. Isolated rat hearts were subjected to ordinary Langendorff's perfusion, and the right ventricle was cannulated to sample coronary effluent. After equilibration, the coronary flow rate was set constant and the hearts were paced at 300 bpm. Coronary effluent was continuously sampled and mixed with the chemiluminescent probe containing 0.018 mmol/l luminol plus 10 mmol/l H2O2. Chemiluminescence from the mixture of coronary effluent and the probe was continuously measured. No concentration was calibrated by various concentrations (0.5-400 pmol/l) of standard NO solution. The lower detection limit of NO was 1 pmol/l. Basal NO release from isolated perfused rat heart was 0.41 +/- 0.17 pmol/min/ g of heart weight, and that was significantly suppressed by 0.1 mmol/l of L-NAME to 0.18 +/- 0.10 pmol/min/g of heart weight (n = 7). Application of 0.1 and 0.3 mumol/l acetylcholine increased NO level in the coronary effluent, in a concentration-dependent manner, from 6.6 +/- 1.7 in a baseline condition to 16.3 +/- 7.4 and 30.3 +/- 16.1 pmol/l at each peak, respectively. Thrombin at 1 and 10 U/ml also increased NO level from 17.6 +/- 4.3 in control to 35.5 +/- 10.4 and 48.7 +/- 8.7 pmol/l at each peak, respectively (n = 7). Thus, this assay system is applicable to the continuous real-time measurement of NO released from crystalloid perfused hearts, and it may be useful for the study of physiological or pathophysiological role of NO in coronary circulation. (C) 2002 Elsevier Science Inc. All rights reserved.

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  • Hyponatremic-hypertensive syndrome associated with renovascular hypertension - A case report Reviewed

    YT Tetsuou, YY Miyatake, K Tanaka, T Suzuki, F Ohtsu, K Nagasawa, M Fuji-i, S Tanaka, Y Iino, K Tamura

    CIRCULATION JOURNAL   66 ( 3 )   297 - 301   2002.3

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    Renovascular hypertension occasionally manifests clinically as electrolyte disorders and albuminuria in addition to elevated blood pressure. A 49-year-old man who had renovascular hypertension also had severe hypokalemia, hyponatremia, polyuria and polydipsia that were treated by an angiotensin-converting enzyme inhibitor and resection of an atrophic kidney with a compromised blood supply. This is a case of hyponatremic-hypertensive syndrome related to renovascular hypertension and occurring as an additional abnormality.

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  • Clinical significance of increased plasma concentration of macrophage colony-stimulating factor in patients with angina pectoris Reviewed

    T Saitoh, H Kishida, Y Tsukada, Y Fukuma, J Sano, M Yasutake, N Fukuma, Y Kusama, H Hayakawa

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   35 ( 3 )   655 - 665   2000.3

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    Objectives. To determine the effect of macrophage colony-stimulating factor (MCSF) on atherogenesis in patients with coronary artery disease (CAD),we assessed the relation between the plasma concentration of MCSF and the incidence of acute coronary events in patients with CAD.
    Background. Cytokines such as MCSF play a central role in inflammatory and proliferative responses in patients with acute coronary syndromes. However, the effect of MCSF on the clinical course in patients with CAD is still, not known.
    Methods. We measured the plasma MCSF concentration in 142 patients with documented CAD (62 +/- 9 years) and followed up for a mean period of 14 +/- 6 months. The study included 97 patients with stable angina (SA), 45 patients with unstable angina (UA) and 22 age-matched control subjects. The predictors of coronary events were analyzed by using a Cox proportional hazards model.
    Results. The mean plasma MCSF concentration in patients with UA was significantly higher than that in patients with SA and in control subjects (981 +/- 277 vs. 693 +/- 223 vs. 680 +/- 158 pg/ml, p &lt; 0.001). The mean plasma MCSF concentration in the 20 patients with coronary events was significantly higher than that in patients without coronary events (1,192 +/- 232 vs. 690 +/- 213 pg/ml, p &lt; 0.001). The predictors of unfavorable outcome were an increased MCSF concentration, the presence Of CAD and a low ejection fraction.
    Conclusions. These findings suggest that an increased circulating:MCSF concentration reflects atherosclerotic progression in patients with CAD and predicts future cardiac events. (C) 2000 by the American College of Cardiology.

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  • Coronary hyperreactivity to adrenergic stimulation and increased nocturnal vagal tone trigger coronary vasospasm Reviewed

    T Saitoh, H Kishida, A Hanashi, Y Tsukada, Y Fukuma, J Sano, N Fukuma, Y Kusama, H Hayakawa

    JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION   62 ( 10 )   721 - 726   1998.10

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    The relationship between autonomic nervous system activity (ANA) and coronary vasoreactivity during transient myocardial ischemia was determined in patients with vasospastic angina (VA). ANA was measured by power spectral analysis of heart rate variability and humoral factors following intravenous infusion of insulin in 24 patients with VA and 6 control patients. Nine (38%) of the VA patients had significant ST segment depres sion (STD), and 4 of these patients had symptomatic STD. The frequency of anginal episodes in the 9 patients with VA and STD was significantly greater than that in the 15 VA patients without STD (3.4+/-3.1 vs 0.5+/-0.8 episodes/week, p&lt;0.05). The increase in the LF/HF ratio 30 min after insulin injection in patients with STD was significantly greater than that in patients without STD (34+/-31% vs 4+/-34%, p&lt;0.05). All of the patients with VA and STD had significant coronary vasospasm in response to the infusion of less than or equal to 20 iug of acetylcholine, higher levels of nocturnal parasympathetic activity, and greater norepinephrine production in response to insulin stimulation than the VA patients without STD. These findings suggest that increased vagal tone and hyperreactivity to adrenergic stimulation may trigger vasospasm in patients with VA.

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  • Correction to: Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy (Stem Cell Reports, (2018), 10, 3, (942-955), (S2213671118300493), 10.1016/j.stemcr.2018.01.023)

    Aminzadeh, M.A., Rogers, R.G., Fournier, M., Tobin, R.E., Guan, X., Childers, M.K., Andres, A.M., Taylor, D.J., Ibrahim, A., Ding, X., Torrente, A., Goldhaber, J.M., Lewis, M., Gottlieb, R.A., Victor, R.A., Marb{\'a}n, E.

    Stem Cell Reports   21 ( 4 )   2026

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  • Corrigendum to:‘Evaluating the mechanism of action behind controlled hypothermic preservation of donor hearts: A randomized pilot study’(The Journal of Heart and Lung Transplantation, (2025), 44, 7, (1137-1145), (S1053249825018340), 10.1016/j.healun.2025.02.1699)

    Razavi, A.A., Kobashigawa, J., Stotland, A., Chen, Q., Patel, J., Emerson, D., Mirocha, J., Bowdish, M.E., Catarino, P., Megna, D., Gunn, T., Rafiei, M., Rai, D., Song, Y., Babalola, O., Daniels, A., Kittleson, M., Kransdorf, E., Nikolova, A., Czer, L., Chikwe, J., Gottlieb, R.A., Esmailian, F.

    Journal of Heart and Lung Transplantation   45 ( 1 )   2026

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  • 多疾患併存心不全患者における低体重と予後との関連 Reviewed

    太良 修平, 塚田 弥生, 西野 拓也, 加藤 活人, 淺井 邦也

    日本循環器病予防学会誌   60 ( 2 )   187 - 187   2025.5

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  • 救急総合診療領域における医療DXの最前線 川崎市救急業務の効率化に関する実証実験とテンソル心電図による心電図のデジタル符号化に関する取り組みについて Invited

    塚田(哲翁)弥生, 塚田(哲翁)弥生

    日本医科大学医学会雑誌   21 ( 1 )   3 - 10   2025

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  • The Role of Autophagy and Mitophagy in Cardiomyocyte Ischemic Injury

    Gottlieb, R.A., Pourpirali, S.

    Learning Materials in Biosciences   Part F9399   2025

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  • Targeted glycophagy ATG8 therapy reverses diabetic heart disease in mice and in human engineered cardiac tissues

    Mellor, K.M., Varma, U., Koutsifeli, P., Curl, C.L., Janssens, J.V., Daniels, L.J., Bernasochi, G.B., Raaijmakers, A.J.A., Annandale, M., Li, X., James, S.L., Taylor, D.J., Raedschelders, K., Weeks, K.L., Mills, R.J., Parton, R.G., Hu, X., Bell, J.R., O?Brien, T.J., Katare, R., Porrello, E.R., Hudson, J.E., Xiao, R.P., Van Eyk, J.E., Gottlieb, R.A., Delbridge, L.M., D

    Nature Cardiovascular Research   4 ( 11 )   2025

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  • Radiation reprograms fibroblasts to drive prostate cancer therapy resistance

    Madhav, A., Thiruvalluvan, M., Duong, F., Rohena-Rivera, K., Mishra, R., Billet, S., Tripathi, M., Angara, B., Stotland, A., Andres, A., Liu, Z., Gottlieb, R.A., Zumsteg, Z.S., Bhowmick, N.A.

    Endocrine Related Cancer   32 ( 12 )   2025

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  • 急速進行性の下肢末梢神経障害と付随症状から胸髄腫瘍の診断に至った1例 Reviewed

    礒谷 祥太, 川端 真里佐, 光永 周平, 中込 裕太, 高橋 康大, 田原 重志, 塚田 弥生, 岳野 光洋

    日本病院総合診療医学会雑誌   20 ( 臨増1 )   193 - 193   2024.3

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  • 急速進行性の下肢末梢神経障害と付随症状から胸髄腫瘍の診断に至った1例 Reviewed

    礒谷 祥太, 川端 真里佐, 光永 周平, 中込 裕太, 高橋 康大, 田原 重志, 塚田 弥生, 岳野 光洋

    日本病院総合診療医学会雑誌   20 ( 臨増1 )   193 - 193   2024.3

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  • Methods for detection of cardiac glycogen-autophagy

    Koutsifeli, P., Daniels, L.J., Neale, J., Fong, S., Varma, U., Annandale, M., Li, X., Nursalim, Y., Bell, J.R., Weeks, K.L., Stotland, A., Taylor, D.J., Gottlieb, R.A., Delbridge, L.M.D., Mellor, K.M.

    Autophagy Reports   3 ( 1 )   2024

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  • Sex Differences in Cardiovascular Disease-Related Hospitalization and Mortality in Japan ― Analysis of Health Records From a Nationwide Claim-Based Database, the Japanese Registry of All Cardiac and Vascular Disease (JROAD) ― Reviewed

    Noma, S., Kato, K., Otsuka, T., Nakao, Y.M., Aoyama, R., Nakayama, A., Mizuno, A., Kanki, S., Wada, Y., Watanabe, Y., Aoki-Kamiya, C., Hoshina, K., Takahashi, S., Bando, Y., Ide, T., Honye, J., Harada-Shiba, M., Saito, A., Nakano, Y., Sakata, Y., Soejima, K., Maemura, K., Tsukada, Y.T.

    Circulation Journal   88 ( 8 )   2024

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  • 【患者さんの質問にどう答えますか?-言葉の意味を読み解きハートに響く返答集】説明・回答にまつわるエトセトラ 自分はどうしてこんなに体調が悪いのですか?『ドクターショッピング』をする患者さん Invited

    米本 崇子, 塚田 弥生[哲翁]

    Medicina   60 ( 11 )   1890 - 1890   2023.10

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  • 四肢の腫脹と関節症状を初発症状とした後天性血友病Aの2例 Reviewed

    川端 真里佐, 岳野 光洋, 塚田 弥生, 脇田 知志, 安武 正弘

    日本病院総合診療医学会雑誌   19 ( 臨増2 )   147 - 147   2023.8

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  • 未来の医療機器・デバイスのために(Novel Wearable Device with Tensor ECG for Comprehensive Monitoring in the Patients with Heart Failure) Invited Reviewed

    岩崎 雄樹, 塚田 信吾, 塚田 弥生, 村田 広茂, 淀川 顕司, 山本 剛, 清水 渉

    日本循環器学会学術集会抄録集   87回   SY03 - 5   2023.3

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  • 今だからこそ考える:循環器領域における健康の社会的決定要因について 健康の社会的決定要因(SDH)と心血管疾患(Social Determinants of Health and Cardiovascular Disease) Invited Reviewed

    鈴木 隆宏, Mizuno Atsushi, Yasui Haruyo, Noma Satsuki, Omori Takashi, Tetsuou Tsukada Yayoi

    日本循環器学会学術集会抄録集   87回   PD2 - 1   2023.3

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  • 頭痛を契機に診断に至った神経型ベーチェット病の1例 リウマチ性疾患における無菌性髄膜炎の鑑別 Reviewed

    石井 昌嗣, 川端 真里佐, 岳野 光洋, 塚田 弥生, 安武 正弘

    日本病院総合診療医学会雑誌   19 ( 臨増1 )   257 - 257   2023.2

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  • MTX長期内服中に認められた医原性免疫不全関連リンパ増殖性疾患の1例 Reviewed

    佐藤 路子, 塚田 弥生, 勝俣 範之, 岳野 光洋, 許田 典男, 香中 優美, 梶本 雄介

    日本病院総合診療医学会雑誌   18 ( 臨増2 )   235 - 235   2022.8

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  • Trends in Health Issues of Overseas Business Travelers in the post-COVID-19 era

    塚田(哲翁)弥生, 塚田(哲翁)弥生, 安武正弘

    日本熱帯医学会大会プログラム抄録集   18 ( 臨増1 )   O - 090   2022.2

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  • Plasma brain injury markers are associated with volume status but not muscle health in heart failure patients

    Lahiri, S., Mastali, M., Van Eyk, J.E., Hitzeman, T.C., Bresee, C., Raedschelders, K., Lyden, P.D., Gottlieb, R.A., Fang, J.C., Shaw, R.M., Hong, T.T.

    Frontiers in Drug Discovery   2   2022

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    DOI： 10.3389/fddsv.2022.1042737

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  • Mitochondria and Their Cell Hosts: Best of Frenemies

    Andres, A.M., Pourpirali, S., Gottlieb, R.A.

    Advances in Biochemistry in Health and Disease   18   2022

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    DOI： 10.1007/978-3-030-78799-8_10

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  • 急性髄膜炎で発症したベーチェット病の1例 Reviewed

    川端 真里佐, 櫻庭 未多, 酒巻 雅典, 塚田 弥生, 岳野 光洋

    日本内科学会関東地方会   673回   60 - 60   2021.11

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  • 「総合性」と「専門性」の両立—─ポスト・コロナ時代の循環器地域診療を考える Invited

    塚田(哲翁) 弥生

    心臓   53 ( 4 )   315 - 315   2021.4

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    DOI： 10.11281/shinzo.53.315

    CiNii Research

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  • 急性心筋梗塞および2型糖尿病患者におけるエンパグリフロジンの腎保護効果 EMBODY Trialのサブグループ解析(Renoprotective Effects of Empagliflozin in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus: Subgroup Analysis of the EMBODY Trial) Reviewed

    茂澤 幸右, 久保田 芳明, 星加 優, 太良 修平, 時田 祐吉, 淀川 顕司, 岩崎 雄樹, 山本 剛, 高野 仁司, 塚田 弥生, 浅井 邦也, 宮本 正章, 宮内 靖史, 小谷 英太郎, 丸山 光紀, 田邊 潤, 清水 渉

    日本循環器学会学術集会抄録集   85回   OJ70 - 2   2021.3

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  • Renoprotective Effects of Empagliflozin in Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus: Subgroup Analysis of the EMBODY Trial(和訳中) Reviewed

    茂澤 幸右, 久保田 芳明, 星加 優, 太良 修平, 時田 祐吉, 淀川 顕司, 岩崎 雄樹, 山本 剛, 高野 仁司, 塚田 弥生, 浅井 邦也, 宮本 正章, 宮内 靖史, 小谷 英太郎, 丸山 光紀, 田邊 潤, 清水 渉

    日本循環器学会学術集会抄録集   85回   OJ70 - 2   2021.3

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    DOI： 10.1161/circ.142.suppl_3.13625

    Web of Science

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  • 外科系医師のワーク・ライフバランスの現状と医学教育・研修における可能性について

    海原 純子, 錦谷 まりこ, 早坂 明哲, 藤倉 輝道, 前田 美穂, 塚田 弥生[哲翁]

    日本鼻科学会会誌   59 ( 4 )   325 - 334   2020.12

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    外科系医師を中心に継続的な就労の要因としてのワーク・ライフバランスを理解し,必要な支援を考えることが本研究の目的である。大学の同窓会や地域の医師会に呼びかけ,現役の医師に対してワーク・ライフバランスとともに,職業環境,家事負担,生活や仕事への満足度,健康状態等に関する調査を行った。また,医学教育による意識の変化を測るため,医学生に対し2年時と卒業前の6年時におけるワーク・ライフバランスの価値について質問した。女性医師は男性医師に比し家事育児による負担感からワーク・ライフコンフリクトの生じる可能性が示された。特に外科系医師は,そうでない医師に比べて時間的な問題で仕事由来のコンフリクトが大きいことが示唆された。医学生のワーク・ライフバランスの重要性に関する意見は,女子医学生のほうが重要と考えるものが多かったが,卒前の6年時の調査結果で男女間の差は小さくなった。家事育児の性別役割分担への考えは,生育家庭から影響を受けることが示唆され,労働時間など職場環境の改善のほか,大学の医学教育の充実も,医師などの専門職の就労継続に効果のある可能性が示唆された。(著者抄録)

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  • 高齢女性における循環器疾患

    塚田(哲翁)弥生

    臨床雑誌 内科   126 ( 5 )   957 - 960   2020.11

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  • レンバチニブを投与した高齢者の未分化癌の1例 Reviewed

    岡村 律子, 齋藤 麻梨恵, 杉谷 厳, 塚田 弥生, 安武 正弘

    日本老年医学会雑誌   57 ( 4 )   529 - 529   2020.10

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  • 2018-2019年シーズン流行期の成人ヒトパルボウイルスB19感染症の臨床的特徴

    吉村 祐亮, 柴山 雅行, 岡村 律子, 塚田 弥生[哲翁], 望月 徹, 岳野 光洋, 松田 潔, 安武 正弘

    日本病院総合診療医学会雑誌   15 ( 6 )   582 - 582   2019.11

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  • 新専門医制度における若手循環器医師の育成と問題点 循環器と一般内科の二つの専門医認定を受けるための柔軟な研修プログラム(Flexible Training Program for Double Board Certifications with Cardiology and General Medicine) Reviewed

    哲翁 弥生[塚田], 佐藤 直樹, 安武 正弘, 清水 渉

    日本循環器学会学術集会抄録集   83回   SY27 - 2   2019.3

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  • Pushing the Heart Over a KLF(15)

    Gottlieb, R.A., Bhowmick, N.A.

    Journal of the American College of Cardiology   74 ( 14 )   2019

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    DOI： 10.1016/j.jacc.2019.08.021

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  • Matrix-guided control of mitochondrial function in cardiac myocytes

    Lyra-Leite, D.M., Andres, A.M., Cho, N., Petersen, A.P., Ariyasinghe, N.R., Kim, S.S., Gottlieb, R.A., McCain, M.L.

    Acta Biomaterialia   97   2019

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    DOI： 10.1016/j.actbio.2019.08.007

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  • Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling

    Pires, K.M., Torres, N.S., Buffolo, M., Gunville, R., Schaaf, C., Davis, K., Selzman, C.H., Gottlieb, R.A., Boudina, S.

    Antioxidants and Redox Signaling   31 ( 6 )   2019

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    DOI： 10.1089/ars.2018.7640

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  • Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury

    Marek-Iannucci, S., Thomas, A., Hou, J., Crupi, A., Sin, J., Taylor, D.J., Czer, L.S., Esmailian, F., Mentzer, R.M., Andres, A.M., Gottlieb, R.A.

    Scientific Reports   9 ( 1 )   2019

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    DOI： 10.1038/s41598-019-46452-w

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  • Coxsackievirus B infection induces the extracellular release of miR-590-5p, a proviral microRNA

    Germano, J.F., Sawaged, S., Saadaeijahromi, H., Andres, A.M., Feuer, R., Gottlieb, R.A., Sin, J.

    Virology   529   2019

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    DOI： 10.1016/j.virol.2019.01.025

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  • Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

    Murray, B., Peng, H., Barbier-Torres, L., Robinson, A.E., nd Li, T.W.H., Fan, W., Tomasi, M.L., Gottlieb, R.A., Van Eyk, J., Lu, Z., Mart{\'i}nez-Chantar, M.L., Liangpunsakul, S., Skill, N.J., Mato, J.M., Lu, S.C.

    Hepatology   70 ( 6 )   2019

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    DOI： 10.1002/hep.30762

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  • Autophagy plays a protective role against Trypanosoma cruzi infection in mice

    Casassa, A.F., Vanrell, M.C., Colombo, M.I., Gottlieb, R.A., Romano, P.S.

    Virulence   10 ( 1 )   2019

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    DOI： 10.1080/21505594.2019.1584027

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  • Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis

    Onat, U.I., Yildirim, A.D., Tufanli, {\"O., ?imen, I., Kocat{\"u}rk, B., Veli, Z., Hamid, S.M., Shimada, K., Chen, S., Sin, J., Shah, P.K., Gottlieb, R.A., Arditi, M., Erbay, E.

    Journal of the American College of Cardiology   73 ( 10 )   2019

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    DOI： 10.1016/j.jacc.2018.12.055

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  • Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis

    Matundan, H.H., Sin, J., Rivas, M.N., Fishbein, M.C., Lehman, T.J., Chen, S., Gottlieb, R.A., Crother, T.R., Abe, M., Arditi, M.

    Jci Insight   4 ( 3 )   2019

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    DOI： 10.1172/jci.insight.126279

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  • Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis

    Piplani, H., Marek-Iannucci, S., Sin, J., Hou, J., Takahashi, T., Sharma, A., de Freitas Germano, J., Waldron, R.T., Saadaeijahromi, H., Song, Y., Gulla, A., Wu, B., Lugea, A., Andres, A.M., Gaisano, H.Y., Gottlieb, R.A., Pandol, S.J.

    Biochimica Et Biophysica Acta Molecular Basis of Disease   1865 ( 11 )   2019

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    DOI： 10.1016/j.bbadis.2019.08.006

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  • Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria

    Liang, S., Zhong, Z., Kim, S.Y., Uchiyama, R., Roh, Y.S., Matsushita, H., Gottlieb, R.A., Seki, E.

    Journal of Biological Chemistry   294 ( 33 )   2019

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    DOI： 10.1074/jbc.RA119.007409

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  • Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop

    Tian, R., Colucci, W.S., Arany, Z., Bachschmid, M.M., Ballinger, S.W., Boudina, S., Bruce, J.E., Busija, D.W., Dikalov, S., Dorn, G.W., Galis, Z.S., Gottlieb, R.A., Kelly, D.P., Kitsis, R.N., Kohr, M.J., Levy, D., and Lewandowski, E.D., McClung, J.M., Mochly-Rosen, D., O{'}Brien, K.D., O{'}Rourke, B., Park, J.-Y., Ping, P., Sack, M.N., Sheu, S.-S., Shi, Y., Shiva, S., Wallace, D.C., Weiss, R.G., Vernon, H.J., Wong, R., Schwartz Longacre, L.

    Circulation   140 ( 14 )   2019

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    DOI： 10.1161/circulationaha.119.040551

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  • Retracted Article: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives (Nature Communications, (2017), 8, 1, (219), 10.1038/s41467-017-00254-8)

    Rajamani, U., Gross, A.R., Ocampo, C., Andres, A.M., Gottlieb, R.A., Sareen, D.

    Nature Communications   10 ( 1 )   2019

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    DOI： 10.1038/s41467-019-08572-9

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  • 非典型的な臨床経過をたどり、心膜液貯留を契機に診断に至ったIgG4関連疾患の1例 Reviewed

    土方 奈奈子, 山本 哲平, 菅原 一樹, 西 祐吾, 野間 さつき, 吉永 綾, 岩崎 雄樹, 塚田 弥生, 浅井 邦也, 清水 渉

    日本内科学会雑誌   107 ( 7 )   1357 - 1362   2018.7

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    79歳男。約5年前に皮膚そう痒と四肢浮腫が出現し、前医で好酸球性血管性浮腫が疑われた。更に同時期に腹水貯留と腸管壁浮腫を認め、各種検査を行うも特異的な所見は認めなかった。経過より好酸球増多症候群が強く疑われ、プレドニゾロン(PSL)内服の開始にて腹水は消失した。約4年でPSLは中止したが、今回、皮膚そう痒と下腿浮腫が再発した。CTで大量の心膜液貯留を認め、血液検査で末梢血好酸球増多、血清IgEとIgG4の高値を認めた。MRIでは慢性心膜炎の所見を認めたが、心膜穿刺の細胞診で好酸球や形質細胞の増加はなく、悪性所見もなかった。経過中に突然尿閉と発熱を来たし、前立腺腫大を伴わない原発性性腺機能低下症を認めた。前立腺組織診で線維化を伴う慢性炎症を認め、IgG4/IgG形質細胞比が40%以上であったことから、臨床所見と併せてIgG4関連疾患と診断した。診断時には諸症状が軽快し、ステロイド性骨粗鬆症に起因する大腿骨頸部骨折が続発したため、ステロイドによる治療は行わず、定期的に検査を行う方針とし退院とした。

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  • 非典型的な臨床経過をたどり、心膜液貯留を契機に診断に至ったIgG4関連疾患の1例

    土方 奈奈子, 山本 哲平, 菅原 一樹, 西 祐吾, 野間 さつき, 吉永 綾, 岩崎 雄樹, 塚田 弥生, 浅井 邦也, 清水 渉

    日本内科学会雑誌   107 ( 7 )   1357 - 1362   2018.7

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  • 海外臨床研修における血液・体液暴露事故対策

    塚田 弥生, 小久保 まゆみ, Wang Shu, 荻野 良隆, 新田 隆

    CAMPUS HEALTH   55 ( 1 )   257 - 259   2018.3

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  • Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming

    Mishra, R., Haldar, S., Placencio, V., Madhav, A., Rohena-Rivera, K., Agarwal, P., Duong, F., Angara, B., Tripathi, M., Liu, Z., Gottlieb, R.A., Wagner, S., Posadas, E.M., Bhowmick, N.A.

    Journal of Clinical Investigation   128 ( 10 )   2018

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    DOI： 10.1172/JCI99397

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  • Cutting edge: Mitochondrial assembly of the NLRP3 inflammasome complex is initiated at priming

    Elliott, E.I., Miller, A.N., Banoth, B., Iyer, S.S., Stotland, A., Weiss, J.P., Gottlieb, R.A., Sutterwala, F.S., Cassel, S.L.

    Journal of Immunology   200 ( 9 )   2018

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    DOI： 10.4049/jimmunol.1701723

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  • Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses

    Rajamani, U., Gross, A.R., Hjelm, B.E., Sequeira, A., Vawter, M.P., Tang, J., Gangalapudi, V., Wang, Y., Andres, A.M., Gottlieb, R.A., Sareen, D.

    Cell Stem Cell   22 ( 5 )   2018

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    DOI： 10.1016/j.stem.2018.03.009

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  • Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy

    Aminzadeh, M.A., Rogers, R.G., Fournier, M., Tobin, R.E., Guan, X., Childers, M.K., Andres, A.M., Taylor, D.J., Ibrahim, A., Ding, X., Torrente, A., Goldhaber, J.M., Lewis, M., Gottlieb, R.A., Victor, R.A., Marb{\'a}n, E.

    Stem Cell Reports   10 ( 3 )   2018

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    DOI： 10.1016/j.stemcr.2018.01.023

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  • Periodontal disease and its connection to systemic biomarkers of cardiovascular disease in young american Indian/Alaskan natives

    Delange, N., Lindsay, S., Lemus, H., Finlayson, T.L., Kelley, S.T., Gottlieb, R.A.

    Journal of Periodontology   89 ( 2 )   2018

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    DOI： 10.1002/JPER.17-0319

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  • Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging

    Crupi, A.N., Nunnelee, J.S., Taylor, D.J., Thomas, A., Vit, J.-P., Riera, C.E., Gottlieb, R.A., Goodridge, H.S.

    Aging   10 ( 11 )   2018

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    DOI： 10.18632/aging.101643

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  • Antagonizing CD105 enhances radiation sensitivity in prostate cancer

    Madhav, A., Andres, A., Duong, F., Mishra, R., Haldar, S., Liu, Z., Angara, B., Gottlieb, R., Zumsteg, Z.S., Bhowmick, N.A.

    Oncogene   37 ( 32 )   2018

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    Biology of Sex Differences   9 ( 1 )   2018

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    Publishing type：Research paper (scientific journal)  

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    Circulation Research   122 ( 2 )   2018

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    Journal of Visualized Experiments   2018 ( 138 )   2018

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    American Journal of Physiology Heart and Circulatory Physiology   315 ( 5 )   2018

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    日本心臓病学会学術集会抄録   65回   P - 435   2017.9

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    日本循環器学会学術集会抄録集   81回   OE - 234   2017.3

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    Gottlieb, R.A.

    Journal of the American College of Cardiology   70 ( 12 )   2017

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    DOI： 10.1016/j.jacc.2017.07.772

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    American Journal of Physiology Heart and Circulatory Physiology   313 ( 4 )   2017

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    Gottlieb, R.A., Thomas, A.

    Current Pathobiology Reports   5 ( 2 )   2017

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    Taylor, D., Gottlieb, R.A.

    Obesity   25 ( 4 )   2017

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    Nature Reviews Cardiology   14 ( 11 )   2017

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    DOI： 10.1038/nrcardio.2017.102

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    Life Sciences   186   2017

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    DOI： 10.1016/j.lfs.2017.07.035

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    Lipids in Health and Disease   16 ( 1 )   2017

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    Stastna, M., Gottlieb, R.A., Van Eyk, J.

    Expert Review of Proteomics   14 ( 6 )   2017

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    DOI： 10.1080/14789450.2017.1333424

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    Autophagy   13 ( 8 )   2017

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    Journal of Virology   91 ( 24 )   2017

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    Nature Communications   8 ( 1 )   2017

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    Nature Reviews Cardiology   14 ( 7 )   2017

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    DOI： 10.1038/nrcardio.2017.35

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    Stotland, A., Gottlieb, R.A.

    Journal of Molecular and Cellular Cardiology   90   2016

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    DOI： 10.1016/j.yjmcc.2015.11.032

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    Cardio Oncology Principles Prevention and Management   2016

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  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Arozena, A.A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., Adhihetty, P.J., Adler, S.G., Agam, G., Agarwal, R., Aghi, M.K., Agnello, M., Agostinis, P., Aguilar, P.V., Aguirre-Ghiso, J., Airoldi, E.M., Ait-Si-Ali, S., Akematsu, T., Akporiaye, E.T., Al-Rubeai, M., Albaiceta, G.M., Albanese, C., Albani, D., Albert, M.L., Aldudo, J., Alg{\"u}l, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E.S., Alonso, C., Altan-Bonnet, N., Altieri, D.C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A.O., Amessou, M., Amon, A., An, Z., Anania, F.A., Andersen, S.U., Andley, U.P., Andreadi, C.K., Andrieu-Abadie, N., Anel, A., Ann, D.K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A.R., Armstrong, J.L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S.S., Atkin, J.D., Attardi, L.D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M.L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J.M., Bae, D.-H., Bae, J.-S., Bae, O.-N., Bae, S.H., Baehrecke, E.H., Baek, S.-H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X.-Y., Bailly, Y., Balaji, K.N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., B{\'a}nhegyi, G., Bao, H., Barbeau, B., Barrachina, M.D., Barreiro, E., Bartel, B., Bartolom{\'e}, A., Bassham, D.C., Bassi, M.T., Bast, R.C., Basu, A., Batista, M.T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B.L., Bayer, K.U., Beale, R., Beaulieu, J.-F., Beck, G.R., Becker, C., Beckham, J.D., B{\'e}dard, P.-A., Bednarski, P.J., Begley, T.J., Behl, C., Behrends, C., Behrens, G.M.N., Behrns, K.E., Bejarano, E., Belaid, A., Belleudi, F., B{\'e}nard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A.S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S.K., Biagosch, C., Bianchi, M.W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S.W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G.A., Blomhoff, H.K., Boada-Romero, E., B{\"o}ckler, S., Boes, M., Boesze-Battaglia, K., Boise, L.H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L.M., Botti, J., Bou, G., Bouch{\'e}, M., Bouchecareilh, M., Boucher, M.-J., Boulton, M.E., Bouret, S.G., Boya, P., Boyer-Guittaut, M., Bozhkov, P.V., Brady, N., Braga, V.M.M., Brancolini, C., Braus, G.H., Bravo-San-Pedro, J.M., Brennan, L.A., Bresnick, E.H., Brest, P., Bridges, D., Bringer, M.-A., Brini, M., Brito, G.C., Brodin, B., Brookes, P.S., Brown, E.J., Brown, K., Broxmeyer, H.E., Bruhat, A., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bryson-Richardson, R.J., Buch, S., Buchan, A.M., Budak, H., Bulavin, D.V., Bultman, S.J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R.E., Burmeister, M., B{\"u}tikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G.R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A.B., Caraglia, M., Cardinali, C., Cardoso, S.M., Carew, J.S., Carleton, L.A., Carlin, C.R., Carloni, S., Carlsson, S.R., Carmona-Gutierrez, D., Carneiro, L.A.M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A.I., Ce{\~n}a, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H.-J., Chagin, A.S., Chai, C.-Y., Chakrabarti, G., Chamilos, G., Chan, E.Y.W., Chan, M.T.V., Chandra, D., Chandra, P., Chang, C.-P., Chang, R.C.-C., Chang, T.Y., Chatham, J.C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M.E., Cheluvappa, R., Chen, C.-J., Chen, G., Chen, G.-C., Chen, G., Chen, H., Chen, J.W., Chen, J.-K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S.-D., Chen, S., Chen, S.S.-L., Chen, W., Chen, W.-J., Chen, W.Q., Chen, W., Chen, X., Chen, Y.-H., Chen, Y.-G., Chen, Y., Chen, Y., Chen, Y., Chen, Y.-J., Chen, Y.-Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C.H.K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C.H.A., Chevet, E., Chi, H.C., Chi, S.-G., Chiacchiera, F., Chiang, H.-L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L.-S., Chiong, M., Chiu, G.N.C., Cho, D.-H., Cho, S.-G., Cho, W.C., Cho, Y.-Y., Cho, Y.-S., Choi, A.M.K., Choi, E.-J., Choi, E.-K., Choi, J., Choi, M.E., Choi, S.-I., Chou, T.-F., Chouaib, S., Choubey, D., Choubey, V., Chow, K.-C., Chowdhury, K., Chu, C.T., Chuang, T.-H., Chun, T., Chung, H., Chung, T., Chung, Y.-L., Chwae, Y.-J., Cianfanelli, V., Ciarcia, R., Ciechomska, I.A., Ciriolo, M.R., Cirone, M., Claerhout, S., Clague, M.J., Cl{\`a}ria, J., Clarke, P.G.H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E.M., Cocco, T., Codogno, P., Coers, J., Cohen, E.E.W., Colecchia, D., Coletto, L., Coll, N.S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K.L., Coombs, G.H., Cooper, C.D., Cooper, J.M., Coppens, I., Corasaniti, M.T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M.D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S.L., Coto-Montes, A., Cottet, S., Couve, E., Covey, L.R., Cowart, L.A., Cox, J.S., Coxon, F.P., Coyne, C.B., Cragg, M.S., Craven, R.J., Crepaldi, T., Crespo, J.L., Criollo, A., Crippa, V., Cruz, M.T., Cuervo, A.M., Cuezva, J.M., Cui, T., Cutillas, P.R., Czaja, M.J., Czyzyk-Krzeska, M.F., Dagda, R.K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K.N., Valle, L.D., Dalmasso, G., D{'}amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V.M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C.R., Davey, H.M., Davids, L.M., D{\'a}vila, D., Davis, R.J., Dawson, T.M., Dawson, V.L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, R.C.B.Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G.R.Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J.-P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D.P., Delage-Mourroux, R., Delbridge, L.M.D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C.J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T.P., Devenish, R.J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., Di Antonio, A., D{\'i}az-Araya, G., D{\'i}az-Laviada, I., Diaz-Meco, M.T., Diaz-Nido, J., Dickey, C.A., Dickson, R.C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S.P., Ding, C., Ding, W.-X., Ding, Z., Dini, L., Distler, J.H.W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R.C.J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X.C., Dong, X., Dong, Z., Donohue, T.M., Donohue-Jr, T.M., Doran, K.S., D{'}orazi, G., Dorn, G.W., Dosenko, V., Dridi, S., Drucker, L., Du, J., Du, L.-L., Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V.K., Duchen, M.R., Duchosal, M.A., Duez, H., Dugail, I., Dumit, V.I., Duncan, M.C., Dunlop, E.A., Dunn, W.A., Dupont, N., Dupuis, L., Dur{\'a}n, R.V., Durcan, T.M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C.L., Edinger, A.L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N.T., El-Deiry, W.S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C.J.H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A.-M., Engelender, S., Enserink, J.M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J.L., Erman, A., Escalante, R., Eskelinen, E.-L., Espert, L., Esteban-Mart{\'i}nez, L., Evans, T.J., Fabri, M., Fabrias, G., Fabrizi, C., Facchiano, A., F?rgeman, N.J., Faggioni, A., Fairlie, W.D., Fan, C., Fan, D., Fan, J., Fang, S., Fanto, M., Fanzani, A., Farkas, T., Faure, M., Favier, F.B., Fearnhead, H., Federici, M., Fei, E., Felizardo, T.C., Feng, H., Feng, Y., Feng, Y., Ferguson, T.A., Fern{\'a}ndez, ?.F., Fernandez-Barrena, M.G., Fernandez-Checa, J.C., Fern{\'a}ndez-L{\'o}pez, A., Fernandez-Zapico, M.E., Feron, O., Ferraro, E., Ferreira-Halder, C.V., Fesus, L., Feuer, R., Fiesel, F.C., Filippi-Chiela, E.C., Filomeni, G., Fimia, G.M., Fingert, J.H., Finkbeiner, S., Finkel, T., Fiorito, F., Fisher, P.B., Flajolet, M., Flamigni, F., Florey, O., Florio, S., Floto, R.A., Folini, M., Follo, C., Fon, E.A., Fornai, F., Fortunato, F., Fraldi, A., Franco, R., Francois, A., Fran?ois, A., Frankel, L.B., Fraser, I.D.C., Frey, N., Freyssenet, D.G., Frezza, C., Friedman, S.L., Frigo, D.E., Fu, D., Fuentes, J.M., Fueyo, J., Fujitani, Y., Fujiwara, Y., Fujiya, M., Fukuda, M., Fulda, S., Fusco, C., Gabryel, B., Gaestel, M., Gailly, P., Gajewska, M., Galadari, S., Galili, G., Galindo, I., Galindo, M.F., Galliciotti, G., Galluzzi, L., Galluzzi, L., Galy, V., Gammoh, N., Gandy, S., Ganesan, A.K., Ganesan, S., Ganley, I.G., Gannag{\'e}, M., Gao, F.-B., Gao, F., Gao, J.-X., Nannig, L.G., V{\'e}scovi, E.G., Garcia-Mac{\'i}a, M., Garcia-Ruiz, C., Garg, A.D., Garg, P.K., Gargini, R., Gassen, N.C., Gatica, D., Gatti, E., Gavard, J., Gavathiotis, E., Ge, L., Ge, P., Ge, S., Gean, P.-W., Gelmetti, V., Genazzani, A.A., Geng, J., Genschik, P., Gerner, L., Gestwicki, J.E., Gewirtz, D.A., Ghavami, S., Ghigo, E., Ghosh, D., Giammarioli, A.M., Giampieri, F., Giampietri, C., Giatromanolaki, A., Gibbings, D.J., Gibellini, L., Gibson, S.B., Ginet, V., Giordano, A., Giorgini, F., Giovannetti, E., Girardin, S.E., Gispert, S., Giuliano, S., Gladson, C.L., Glavic, A., Gleave, M., Godefroy, N., Gogal, R.M., Gokulan, K., Goldman, G.H., Goletti, D., Goligorsky, M.S., Gomes, A.V., Gomes, L.C., Gomez, H., Gomez-Manzano, C., G{\'o}mez-S{\'a}nchez, R., Gon?alves, D.A.P., Goncu, E., Gong, Q., Gongora, C., Gonzalez, C.B., Gonzalez-Alegre, P., Gonzalez-Cabo, P., Gonz{\'a}lez-Polo, R.A., Goping, I.S., Gorbea, C., Gorbunov, N.V., Goring, D.R., Gorman, A.M., Gorski, S.M., Goruppi, S., Goto-Yamada, S., Gotor, C., Gottlieb, R.A., Gozes, I., Gozuacik, D., Graba, Y., Graef, M., Granato, G.E., Grant, G.D., Grant, S., Gravina, G.L., Green, D.R., Greenhough, A., Greenwood, M.T., Grimaldi, B., Gros, F., Grose, C., Groulx, J.-F., Gruber, F., Grumati, P., Grune, T., Guan, J.-L., Guan, K.-L., Guerra, B., Guillen, C., Gulshan, K., Gunst, J., Guo, C., Guo, L., Guo, M., Guo, W., Guo, X.-G., Gust, A.A., Gustafsson, ?, B, Gutierrez, E., Gutierrez, M.G., Gwak, H.-S., Haas, A., Haber, J.E., Hadano, S., Hagedorn, M., Hahn, D.R., Halayko, A.J., Hamacher-Brady, A., Hamada, K., Hamai, A., Hamann, A., Hamasaki, M., Hamer, I., Hamid, Q., Hammond, E.M., Han, F., Han, W., Handa, J.T., Hanover, J.A., Hansen, M., Harada, M., Harhaji-Trajkovic, L., Harper, J.W., Harrath, A.H., Harris, A.L., Harris, J., Hasler, U., Hasselblatt, P., Hasui, K., Hawley, R.G., Hawley, T.S., He, C., and He, C.Y., and He, F. and He, G. and He, R.-R. and He, X.-H., and He, Y.-W., He, Y.-Y., Heath, J.K., H{\'e}bert, M.-J., Heinzen, R.A., Helgason, G.V., Hensel, M., Henske, E.P., Her, C., Herman, P.K., Hern{\'a}ndez, A., Hernandez, C., Hern{\'a}ndez-Tiedra, S., Hetz, C., Hiesinger, P.R., Higaki, K., Hilfiker, S., Hill, B.G., Hill, J.A., Hill, W.D., Hino, K., Hofius, D., Hofman, P., H{\"o}glinger, G.U., H{\"o}hfeld, J., Holz, M.K., Hong, Y., Hood, D.A., Hoozemans, J.J.M., Hoppe, T., Hsu, C., Hsu, C.-Y., Hsu, L.-C., Hu, D., Hu, G., Hu, H.-M., Hu, H., Hu, M.C., Hu, Y.-C., Hu, Z.-W., Hua, F., Hua, Y., Huang, C., Huang, H.-L., Huang, K.-H., Huang, K.-Y., Huang, S., Huang, S., Huang, W.-P., Huang, Y.-R., Huang, Y., Huang, Y., Huber, T.B., Huebbe, P., Huh, W.-K., Hulmi, J.J., Hur, G.M., Hurley, J.H., Husak, Z., Hussain, S.N.A., Hussain, S., Hwang, J.J., Hwang, S., Hwang, T.I.S., Ichihara, A., Imai, Y., Imbriano, C., Inomata, M., Into, T., Iovane, V., Iovanna, J.L., Iozzo, R.V., Ip, N.Y., Irazoqui, J.E., Iribarren, P., Isaka, Y., Isakovic, A.J., Ischiropoulos, H., Isenberg, J.S., Ishaq, M., Ishida, H., Ishii, I., Ishmael, J.E., Isidoro, C., Isobe, K.-I., Isono, E., Issazadeh-Navikas, S., Itahana, K., Itakura, E., Ivanov, A.I., Iyer, A.K.V., Izquierdo, J.M., Izumi, Y., Izzo, V., J, a, a}ttel{\"a}, M., Jaber, N., Jackson, D.J., Jackson, W.T., Jacob, T.G., Jacques, T.S., Jagannath, C., Jain, A., Jana, N.R., Jang, B.K., Jani, A., Janji, B., Jannig, P.R., Jansson, P.J., Jean, S., Jendrach, M., Jeon, J.-H., Jessen, N., Jeung, E.-B., Jia, K., Jia, L., Jiang, H., Jiang, H., Jiang, L., Jiang, T., Jiang, X., Jiang, X., Jiang, Y., Jiang, Y., Jim{\'e}nez, A., Jin, C., Jin, H., Jin, L., Jin, M., Jin, S., Jinwal, U.K., Jo, E.-K., Johansen, T., Johnson, D.E., Johnson, G.V.W., Johnson, J.D., Jonasch, E., Jones, C., Joosten, L.A.B., Jordan, J., Joseph, A.-M., Joseph, B., Joubert, A.M., Ju, D., Ju, J., Juan, H.-F., Juenemann, K., Juh{\'a}sz, G., Jung, H.S., Jung, J.U., Jung, Y.-K., Jungbluth, H., Justice, M.J., Jutten, B., Kaakoush, N.O., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaeffer, B., K?gedal, K., Kahana, A., Kajimura, S., Kakhlon, O., Kalia, M., Kalvakolanu, D.V., Kamada, Y., Kambas, K., Kaminskyy, V.O., Kampinga, H.H., Kandouz, M., Kang, C., Kang, R., Kang, T.-C., Kanki, T., Kanneganti, T.-D., Kanno, H., Kanthasamy, A.G., Kantorow, M., Kaparakis-Liaskos, M., Kapuy, O., Karantza, V., Karim, M.R., Karmakar, P., Kaser, A., Kaushik, S., Kawula, T., Kaynar, A.M., nd Ke, P.-Y., Ke, Z.-J., Kehrl, J.H., Keller, K.E., Kemper, J.K., Kenworthy, A.K., Kepp, O., Kern, A., Kesari, S., Kessel, D., Ketteler, R., Kettelhut, I.C., Khambu, B., Khan, M.M., Khandelwal, V.K.M., Khare, S., Kiang, J.G., Kiger, A.A., Kihara, A., Kim, A.L., Kim, C.H., Kim, D.R., Kim, D.-H., Kim, E.K., Kim, H.Y., Kim, H.-R., Kim, J.-S., Kim, J.H., Kim, J.C., Kim, J.H., Kim, K.W., Kim, M.D., Kim, M.-M., Kim, P.K., Kim, S.W., Kim, S.-Y., Kim, Y.-S., Kim, Y., Kimchi, A., Kimmelman, A.C., Kimura, T., King, J.S., Kirkegaard, K., Kirkin, V., Kirshenbaum, L.A., Kishi, S., Kitajima, Y., Kitamoto, K., Kitaoka, Y., Kitazato, K., Kley, R.A., Klimecki, W.T., Klinkenberg, M., Klucken, J., Kn?velsrud, H., Knecht, E., Knuppertz, L., Ko, J.-L., Kobayashi, S., Koch, J.C., Koechlin-Ramonatxo, C., Koenig, U., Koh, Y.H., K{\"o}hler, K., Kohlwein, S.D., Koike, M., Komatsu, M., Kominami, E., Kong, D., Kong, H.J., Konstantakou, E.G., Kopp, B.T., Korcsmaros, T., Korhonen, L., Korolchuk, V.I., Koshkina, N.V., Kou, Y., Koukourakis, M.I., Koumenis, C., Kov{\'a}cs, A.L., Kov{\'a}cs, T., Kovacs, W.J., Koya, D., Kraft, C., Krainc, D., Kramer, H., Kravic-Stevovic, T., Krek, W., Kretz-Remy, C., Krick, R., Krishnamurthy, M., Kriston-Vizi, J., Kroemer, G., Kruer, M.C., Kruger, R., Ktistakis, N.T., Kuchitsu, K., Kuhn, C., Kumar, A.P., Kumar, A., Kumar, A., Kumar, D., Kumar, D., Kumar, R., Kumar, S., Kundu, M., Kung, H.-J., Kuno, A., Kuo, S.-H., Kuret, J., Kurz, T., Kwok, T., Kwon, T.K., Kwon, Y.T., Kyrmizi, I., La Spada, A.R., Lafont, F., Lahm, T., Lakkaraju, A., Lam, T., Lamark, T., Lancel, S., Landowski, T.H., Lane, D.J.R., Lane, J.D., Lanzi, C., Lapaquette, P., Lapierre, L.R., Laporte, J., Laukkarinen, J., Laurie, G.W., Lavandero, S., Lavie, L., Lavoie, M.J., d Law, B.Y.K., and Law, H.K.-W., Law, K.B., Layfield, R., Lazo, P.A., Le Cam, L., Le Roch, K.G., Le Stunff, H., Leardkamolkarn, V., Lecuit, M., d Lee, B.-H., and Lee, C.-H., Lee, E.F., Lee, G.M., Lee, H.-J., Lee, H., Lee, J.K., Lee, J., Lee, J.-H., Lee, M., and Lee, M.-S. and Lee, P.J. and Lee, S.W. and Lee, S.-J., and Lee, S.-J., and Lee, S.Y., and Lee, S.H., and Lee, S.S., a, d Lee, S.-J., Lee, S., d Lee, Y.-R., Lee, Y.J., Lee, Y.H., Leeuwenburgh, C., Lefort, S., Legouis, R., Lei, J., Lei, Q.-Y., Leib, D.A., Leibowitz, G., Lekli, I., Lemaire, S.D., Lemasters, J.J., Lemberg, M.K., Lemoine, A., Leng, S., Lenz, G., Lenzi, P., Lerman, L.O., Barbato, D.L., Leu, J.I.J., Leung, H.Y., Levine, B., Lewis, P.A., Lezoualch, F., Li, C., Li, F., Li, F.-J., Li, J., Li, K., Li, L., Li, M., Li, Q., Li, R., Li, S., Li, W., Li, X., Li, Y., Lian, J., Liang, C., Liang, Q., Liao, Y., Liberal, J., Liberski, P.P., Lie, P., Lieberman, A.P., Lim, H.J., Lim, K.-L., Lim, K., Lima, R.T., Lin, C.-S., Lin, C.-F., Lin, F., Lin, F., Lin, F.-C., Lin, K., Lin, K.-H., Lin, P.-H., Lin, T., Lin, W.-W., Lin, Y.-S., Lin, Y., Linden, R., Lindholm, D. and L., qvist, L.M., Lingor, P., Linkermann, A., Liotta, L.A., Lipinski, M.M., Lira, V.A., Lisanti, M.P., Liton, P.B., Liu, B., Liu, C., Liu, C.-F., Liu, F., Liu, H.-J., Liu, J., Liu, J.-J., Liu, J.-L., Liu, K., Liu, L., Liu, L., Liu, Q., Liu, R.-Y., Liu, S., Liu, S., Liu, W., Liu, X.-D., Liu, X., Liu, X.-H., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Z., Liu, Z., Liuzzi, J.P., Lizard, G., Ljujic, M., Lodhi, I.J., Logue, S.E., Lokeshwar, B.L., Long, Y.C., Lonial, S., Loos, B., L{\'o}pez-Ot{\'i}n, C., L{\'o}pez-Vicario, C., Lorente, M., Lorenzi, P.L., L{\~o}rincz, P., Los, M., Lotze, M.T., Lovat, P.E., Lu, B., Lu, B., Lu, J., Lu, Q., Lu, S.-M., Lu, S., Lu, Y., Luciano, F., Luckhart, S., Lucocq, J.M., Ludovico, P., Lugea, A., Lukacs, N.W., Lum, J.J., Lund, A.H., Luo, H., Luo, J., Luo, S., Luparello, C., Lyons, T., Ma, J., Ma, Y., Ma, Y., Ma, Z., Machado, J., Machado-Santelli, G.M., Macian, F., MacIntosh, G.C., MacKeigan, J.P., Macleod, K.F., MacMicking, J.D., MacMillan-Crow, L.A., Madeo, F., Madesh, M., Madrigal-Matute, J., Maeda, A., Maeda, T., Maegawa, G., Maellaro, E., Maes, H., Magari{\~n}os, M., Maiese, K., Maiti, T.K., Maiuri, L., Maiuri, M.C., Maki, C.G., Malli, R., Malorni, W., Maloyan, A., Mami-Chouaib, F., Man, N., Mancias, J.D., Mandelkow, E.-M., Mandell, M.A., Manfredi, A.A., Mani{\'e}, S.N., Manzoni, C., Mao, K., Mao, Z., Mao, Z.-W., Marambaud, P., Marconi, A.M., Marelja, Z., Marfe, G., Margeta, M., Margittai, E., Mari, M., Mariani, F.V., Marin, C., Marinelli, S., Mari{\~n}o, G., Markovic, I., Marquez, R., Martelli, A.M., Martens, S., Martin, K.R., Martin, S.J., Martin, S., Martin-Acebes, M.A., Mart{\'i}n-Sanz, P., d Martin, Mari, C., Martinet, W., Martinez, J., Martinez-Lopez, N., Martinez-Outschoorn, U., Mart{\'i}nez-Vel{\'a}zquez, M., Martinez-Vicente, M., Martins, W.K., Mashima, H., Mastrianni, J.A., Matarese, G., Matarrese, P., Mateo, R., Matoba, S., Matsumoto, N., Matsushita, T., Matsuura, A., Matsuzawa, T., Mattson, M.P., Matus, S., Maugeri, N., Mauvezin, C., Mayer, A., Maysinger, D., Mazzolini, G.D., McBrayer, M.K., McCall, K., McCormick, C., McInerney, G.M., McIver, S.C., McKenna, S., McMahon, J.J., McNeish, I.A., Mechta-Grigoriou, F., Medema, J.P., Medina, D.L., Megyeri, K., Mehrpour, M., Mehta, J.L., Mei, Y., Meier, U.-C., Meijer, A.J., Mel{\'e}ndez, A., Melino, G., Melino, S., de Melo, E.J.T., Mena, M.A., Meneghini, M.D., Menendez, J.A., Menezes, R., Meng, L., Meng, L.-H., Meng, S., Menghini, R., Menko, A.S., Menna-Barreto, R.F.S., Menon, M.B., Meraz-R{\'i}os, M.A., Merla, G., Merlini, L., Merlot, A.M., Meryk, A., Meschini, S., Meyer, J.N., Mi, M.-T., Miao, C.-Y., Micale, L., Michaeli, S., Michiels, C., Migliaccio, A.R., Mihailidou, A.S., Mijaljica, D., Mikoshiba, K., Milan, E., Miller-Fleming, L., Mills, G.B., Mills, I.G., Minakaki, G., Minassian, B.A., Ming, X.-F., Minibayeva, F., Minina, E.A., Mintern, J.D., Minucci, S., Miranda-Vizuete, A., Mitchell, C.H., Miyamoto, S., Miyazawa, K., Mizushima, N., Mnich, K., Mograbi, B., Mohseni, S., Moita, L.F., Molinari, M., Molinari, M., M?ller, A.B., Mollereau, B., Mollinedo, F., Mongillo, M., Monick, M.M., Montagnaro, S., Montell, C., Moore, D.J., Moore, M.N., Mora-Rodriguez, R., Moreira, P.I., Morel, E., Morelli, M.B., Moreno, S., Morgan, M.J., Moris, A., Moriyasu, Y., Morrison, J.L., Morrison, L.A., Morselli, E., Moscat, J., Moseley, P.L., Mostowy, S., Motori, E., Mottet, D., Mottram, J.C., Moussa, C.E.-H., Mpakou, V.E., Mukhtar, H., Levy, J.M.M., Muller, S., Mu{\~n}oz-Moreno, R., Mu{\~n}oz-Pinedo, C., M{\"u}nz, C., Murphy, M.E., Murray, J.T., Murthy, A., Mysorekar, I.U., Nabi, I.R., Nabissi, M., Nader, G.A., Nagahara, Y., Nagai, Y., Nagata, K., Nagelkerke, A., Nagy, P., Naidu, S.R., Nair, S., Nakano, H., Nakatogawa, H., Nanjundan, M., Napolitano, G., Naqvi, N.I., Nardacci, R., Narendra, D.P., Narita, M., Nascimbeni, A.C., Natarajan, R., Navegantes, L.C., Nawrocki, S.T., Nazarko, T.Y., Nazarko, V.Y., Neill, T., Neri, L.M., Netea, M.G., Netea-Maier, R.T., Neves, B.M., Ney, P.A., Nezis, I.P., Nguyen, H.T.T., Nguyen, H.P., Nicot, A.-S., Nilsen, H., Nilsson, P., Nishimura, M., Nishino, I., Niso-Santano, M., Niu, H., Nixon, R.A., Njar, V.C.O., Noda, T., Noegel, A.A., Nolte, E.M., Norberg, E., Norga, K.K., Noureini, S.K., Notomi, S., Notterpek, L., Nowikovsky, K., Nukina, N., N{\"u}rnberger, T., O{'}donnell, V.B., O{'}donovan, T., O{'}dwyer, P.J., Oehme, I., Oeste, C.L., Ogawa, M., Ogretmen, B., Ogura, Y., Oh, Y.J., Ohmuraya, M., Ohshima, T., Ojha, R., Okamoto, K., Okazaki, T., Oliver, F.J., Ollinger, K., Olsson, S., Orban, D.P., Ordonez, P., Orhon, I., Orosz, L., O{'}rourke, E.J., Orozco, H., Ortega, A.L., Ortona, E., Osellame, L.D., Oshima, J., Oshima, S., Osiewacz, H.D., Otomo, T., Otsu, K., Ou, J.-H.J., Outeiro, T.F., Ouyang, D.-Y., Ouyang, H., Overholtzer, M., Ozbun, M.A., Ozdinler, P.H., Ozpolat, B., Pacelli, C., Paganetti, P., Page, G., Pages, G., Pagnini, U., Pajak, B., Pak, S.C., Pakos-Zebrucka, K., Pakpour, N., Palkov{\'a}, Z., Palladino, F., Pallauf, K., Pallet, N., Palmieri, M., Paludan, S.R., Palumbo, C., Palumbo, S., Pampliega, O., Pan, H., Pan, W., Panaretakis, T., Pandey, A., Pantazopoulou, A., Papackova, Z., Papademetrio, D.L., Papassideri, I., Papini, A., Parajuli, N., Pardo, J., Parekh, V.V., Parenti, G., Park, J.-I., Park, J., Park, O.K., Parker, R., Parlato, R., Parys, J.B., Parzych, K.R., Pasquet, J.-M., Pasquier, B., Pasumarthi, K.B.S., Patterson, C., Pattingre, S., Pattison, S., Pause, A., Pavenst{\"a}dt, H., Pavone, F., Pedrozo, Z., Pe{\~n}a, F.J., Pe, n}alva, M.A., Pende, M., Peng, J., Penna, F., Penninger, J.M., Pensalfini, A., Pepe, S., Pereira, G.J.S., Pereira, P.C., de la Cruz, V.P., P{\'e}rez-P{\'e}rez, M.E., P{\'e}rez-Rodr{\'i}guez, D., P{\'e}rez-Sala, D., Perier, C., Perl, A., Perlmutter, D.H., Perrotta, I., Pervaiz, S., Pesonen, M., Pessin, J.E., Peters, G.J., Petersen, M., Petrache, I., Petrof, B.J., Petrovski, G., Phang, J.M., Piacentini, M., Pierdominici, M., Pierre, P., Pierrefite-Carle, V., Pietrocola, F., Pimentel-Mui{\~n}os, F.X., Pinar, M., Pineda, B., Pinkas-Kramarski, R., Pinti, M., Pinton, P., Piperdi, B., Piret, J.M., Platanias, L.C., Platta, H.W., Plowey, E.D., P{\"o}ggeler, S., Poirot, M., Pol?ic, P., Poletti, A., Poon, A.H., Popelka, H., Popova, B., Poprawa, I., Poulose, S.M., Poulton, J., Powers, S.K., Powers, T., Pozuelo-Rubio, M., Prak, K., Prange, R., Prescott, M., Priault, M., Prince, S., Proia, R.L., Proikas-Cezanne, T., Prokisch, H., Promponas, V.J., Przyklenk, K., Puertollano, R., Pugazhenthi, S., Puglielli, L., Pujol, A., Puyal, J., Pyeon, D., Qi, X., Qian, W.-B., Qin, Z.-H., Qiu, Y., Qu, Z., Quadrilatero, J., Quinn, F., Raben, N., Rabinowich, H., Radogna, F., Ragusa, M.J., Rahmani, M., Raina, K., Ramanadham, S., Ramesh, R., Rami, A., Randall-Demllo, S., Randow, F., Rao, H., Rao, V.A., Rasmussen, B.B., Rasse, T.M., Ratovitski, E.A., Rautou, P.-E., Ray, S.K., Razani, B., Reed, B.H., Reggiori, F., Rehm, M., Reichert, A.S., Rein, T., Reiner, D.J., Reits, E., Ren, J., Ren, X., Renna, M., Reusch, J.E.B., Revuelta, J.L., Reyes, L., Rezaie, A.R., Richards, R.I., Richardson, R., Richetta, C., Riehle, M.A., Rihn, B.H., Rikihisa, Y., Riley, B.E., Rimbach, G., Rippo, M.R., Ritis, K., Rizzi, F., Rizzo, E., Roach, P.J., Robbins, J., Roberge, M., Roca, G., Roccheri, M.C., Rocha, S., Rodrigues, C.M.P., Rodr{\'i}guez, C.I., de Cordoba, S.R., Rodriguez-Muela, N., Roelofs, J., Rogov, V.V., Rohn, T.T., Rohrer, B., Romanelli, D., Romani, L., Romano, P.S., Roncero, M.I.G., Rosa, J.L., Rosello, A., Rosen, K.V., Rosenstiel, P., Rost-Roszkowska, M., Roth, K.A., Rou{\'e}, G., Rouis, M., Rouschop, K.M., Ruan, D.T., Ruano, D., Rubinsztein, D.C., Rucker, E.B., Rudich, A., Rudolf, E., Rudolf, R., Ruegg, M.A., Ruiz-Roldan, C., Ruparelia, A.A., Rusmini, P., Russ, D.W., Russo, G.L., Russo, G., Russo, R., Rusten, T.E., Ryabovol, V., Ryan, K.M., Ryter, S.W., Sabatini, D.M., Sacher, M., Sachse, C., Sack, M.N., Sadoshima, J., Saftig, P., Sagi-Eisenberg, R., Sahni, S., Saikumar, P., Saito, T., Saitoh, T., Sakakura, K., Sakoh-Nakatogawa, M., Sakuraba, Y., Salazar-Roa, M., Salomoni, P., Saluja, A.K., Salvaterra, P.M., Salvioli, R., Samali, A., Sanchez, A.M.J., S{\'a}nchez-Alc{\'a}zar, J.A., Sanchez-Prieto, R., Sandri, M., Sanjuan, M.A., Santaguida, S., Santambrogio, L., Santoni, G., Dos Santos, C.N., Saran, S., Sardiello, M., Sargent, G., Sarkar, P., Sarkar, S., Sarrias, M.R., Sarwal, M.M., Sasakawa, C., Sasaki, M., Sass, M., Sato, K., Sato, M., Satriano, J., Savaraj, N., Saveljeva, S., Schaefer, L., Schaible, U.E., Scharl, M., Schatzl, H.M., Schekman, R., Scheper, W., Schiavi, A., Schipper, H.M., Schmeisser, H., Schmidt, J., Schmitz, I., Schneider, B.E., Schneider, E.M., Schneider, J.L., Schon, E.A., Sch{\"o}nenberger, M.J., Sch{\"o}nthal, A.H., Schorderet, D.F., Schr{\"o}der, B., Schuck, S., Schulze, R.J., Schwarten, M., Schwarz, T.L., Sciarretta, S., Scotto, K., Scovassi, A.I., Screaton, R.A., Screen, M., Seca, H., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Segu{\'i}-Simarro, J.M., Segura-Aguilar, J., Seiliez, I., Seki, E., Sell, C., Semenkovich, C.F., Semenza, G.L., Sen, U., Serra, A.L., Serrano-Puebla, A., Sesaki, H., Setoguchi, T., Settembre, C., Shacka, J.J., Shajahan-Haq, A.N., Shapiro, I.M., Sharma, S., She, H., Shen, C.-K.J., Shen, C.-C., Shen, H.-M., Shen, S., Shen, W., Sheng, R., Sheng, X., Sheng, Z.-H., Shepherd, T.G., Shi, J., Shi, Q., Shi, Q., Shi, Y., Shibutani, S., Shibuya, K., Shidoji, Y., Shieh, J.-J., Shih, C.-M., Shimada, Y., Shimizu, S., Shin, D.W., Shinohara, M.L., Shintani, M., Shintani, T., Shioi, T., Shirabe, K., Shiri-Sverdlov, R., Shirihai, O., Shore, G.C., Shu, C.-W., Shukla, D., Sibirny, A.A., Sica, V., Sigurdson, C.J., Sigurdsson, E.M., Sijwali, P.S., Sikorska, B., Silveira, W.A., Silvente-Poirot, S., Silverman, G.A., Simak, J., Simmet, T., Simon, A.K., Simon, H.-U., Simone, C., Simons, M., Simonsen, A., Singh, R., Singh, S.V., Singh, S.K., Sinha, D., Sinha, S., Sinicrope, F.A., Sirko, A., Sirohi, K., Sishi, B.J.N., Sittler, A., Siu, P.M., Sivridis, E., Skwarska, A., Slack, R., Slaninov{\'a}, I., Slavov, N., Smaili, S.S., Smalley, K.S.M., Smith, D.R., Soenen, S.J., Soleimanpour, S.A., Solhaug, A., Somasundaram, K., Son, J.H., Sonawane, A., Song, C., Song, F., Song, H.K., Song, J.-X., Song, W., Soo, K.Y., Sood, A.K., Soong, T.W., Soontornniyomkij, V., Sorice, M., Sotgia, F., Soto-Pantoja, D.R., Sotthibundhu, A., Sousa, M.J., Spaink, H.P., Span, P.N., Spang, A., Sparks, J.D., Speck, P.G., Spector, S.A., Spies, C.D., Springer, W., Clair, D.S., Stacchiotti, A., Staels, B., Stang, M.T., Starczynowski, D.T., Starokadomskyy, P., Steegborn, C., Steele, J.W., Stefanis, L., Steffan, J., Stellrecht, C.M., Stenmark, H., Stepkowski, T.M., Stern, S.T., Stevens, C., Stockwell, B.R., Stoka, V., Storchova, Z., Stork, B., Stratoulias, V., Stravopodis, D.J., Strnad, P., Strohecker, A.M., Str{\"o}m, A.-L., Stromhaug, P., Stulik, J., Su, Y.-X., Su, Z., Subauste, C.S., Subramaniam, S., Sue, C.M., Suh, S.W., Sui, X., Sukseree, S., Sulzer, D., Sun, F.-L., Sun, J., Sun, J., Sun, S.-Y., Sun, Y., Sun, Y., Sun, Y., Sundaramoorthy, V., Sung, J., Suzuki, H., Suzuki, K., Suzuki, N., Suzuki, T., Suzuki, Y.J., Swanson, M.S., Swanton, C., Sw{\"a}rd, K., Swarup, G., Sweeney, S.T., Sylvester, P.W., Szatmari, Z., Szegezdi, E., Szlosarek, P.W., Taegtmeyer, H., Tafani, M., Taillebourg, E., Tait, S.W.G., Takacs-Vellai, K., Takahashi, Y., Tak{\'a}ts, S., Takemura, G., Takigawa, N., Talbot, N.J., Tamagno, E., Tamburini, J., Tan, C.-P., Tan, L., Tan, M.L., Tan, M., Tan, Y.-J., Tanaka, K., Tanaka, M., Tang, D., Tang, D., Tang, G., Tanida, I., Tanji, K., Tannous, B.A., Tapia, J.A., Tasset-Cuevas, I., Tatar, M., Tavassoly, I., Tavernarakis, N., Taylor, A., Taylor, G.S., Taylor, G.A., Taylor, J.P., Taylor, M.J., Tchetina, E.V., Tee, A.R., Teixeira-Clerc, F., Telang, S., Tencomnao, T., Teng, B.-B., Teng, R.-J., Terro, F., Tettamanti, G., Theiss, A.L., Theron, A.E., Thomas, K.J., Thom{\'e}, M.P., Thomes, P.G., Thorburn, A., Thorner, J., Thum, T., Thumm, M., Thurston, T.L.M., Tian, L., Till, A., Ting, J.P.-Y., Titorenko, V.I., Toker, L., Toldo, S., Tooze, S.A., Topisirovic, I., Torgersen, M.L., Torosantucci, L., Torriglia, A., Torrisi, M.R., Tournier, C., Towns, R., Trajkovic, V., Travassos, L.H., Triola, G., Tripathi, D.N., Trisciuoglio, D., Troncoso, R., Trougakos, I.P., Truttmann, A.C., Tsai, K.-J., Tschan, M.P., Tseng, Y.-H., Tsukuba, T., Tsung, A., Tsvetkov, A.S., Tu, S., Tuan, H.-Y., Tucci, M., Tumbarello, D.A., Turk, B., Turk, V., Turner, R.F.B., Tveita, A.A., Tyagi, S.C., Ubukata, M., Uchiyama, Y., Udelnow, A., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Underwood, B.R., Ungermann, C., Ureshino, R.P., Ushioda, R., Uversky, V.N., Uzc{\'a}tegui, N.L., Vaccari, T., Vaccaro, M.I., V{\'a}chov{\'a}, L., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, E.M., Vallette, F., Valverde, A.M., Van den Berghe, G., Van Den, Bosch, L., van den Brink, G.R., van der Goot, F.G., van der Klei, I.J., van der Laan, L.J.W., van Doorn, W.G., van Egmond, M., van Golen, K.L., Van Kaer, L., Campagne, M.L., Vandenabeele, P., Vandenberghe, W., Vanhorebeek, I., Varela-Nieto, I., Vasconcelos, M.H., Vasko, R., Vavvas, D.G., Vega-Naredo, I., Velasco, G., Velentzas, A.D., Velentzas, P.D., Vellai, T., Vellenga, E., Vendelbo, M.H., Venkatachalam, K., Ventura, N., Ventura, S., Veras, P.S.T., Verdier, M., Vertessy, B.G., Viale, A., Vidal, M., Vieira, H.L.A., Vierstra, R.D., Vigneswaran, N., Vij, N., Vila, M., Villar, M., Villar, V.H., d, Villarroya, J., Vindis, C., Viola, G., Viscomi, M.T., Vitale, G., Vogl, D.T., Voitsekhovskaja, O.V., von Haefen, C., von Schwarzenberg, K., Voth, D.E., Vouret-Craviari, V., Vuori, K., Vyas, J.M., Waeber, C., Walker, C.L., Walker, M.J., Walter, J., Wan, L., Wan, X., Wang, B., Wang, C., Wang, C.-Y., Wang, C., Wang, C., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H.-J., Wang, H., Wang, H.-G., Wang, H., Wang, H.-D., Wang, J., Wang, J., Wang, M., Wang, M.-Q., Wang, P.-Y., Wang, P., Wang, R.C., Wang, S., Wang, T.-F., Wang, X., Wang, X.-J., Wang, X.-W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.-J., Wang, Y., Wang, Y., Wang, Y.T., Wang, Y., Wang, Z.-N., Wappner, P., Ward, C., Ward, D.M.V., Warnes, G., Watada, H., Watanabe, Y., Watase, K., Weaver, T.E., Weekes, C.D., Wei, J., Weide, T., Weihl, C.C., Weindl, G., Weis, S.N., Wen, L., Wen, X., Wen, Y., Westermann, B., Weyand, C.M., White, A.R., White, E., Whitton, J.L., Whitworth, A.J., Wiels, J., Wild, F., Wildenberg, M.E., Wileman, T., Wilkinson, D.S., Wilkinson, S., Willbold, D., Williams, C., Williams, K., Williamson, P.R., Winklhofer, K.F., Witkin, S.S., Wohlgemuth, S.E., Wollert, T., Wolvetang, E.J., Wong, E., Wong, G.W., Wong, R.W., Wong, V.K.W., Woodcock, E.A., Wright, K.L., Wu, C., Wu, D., Wu, G.S., Wu, J., Wu, J., Wu, M., Wu, M., Wu, S., d Wu, W.K.K., Wu, Y., Wu, Z., Xavier, C.P.R., Xavier, R.J., Xia, G.-X., Xia, T., Xia, W., Xia, Y., Xiao, H., Xiao, J., Xiao, S., Xiao, W., Xie, C.-M., Xie, Z., Xie, Z., Xilouri, M., Xiong, Y., Xu, C., Xu, C., Xu, F., Xu, H., Xu, H., Xu, J., Xu, J., Xu, J., Xu, L., Xu, X., Xu, Y., Xu, Y., Xu, Z.-X., Xu, Z., Xue, Y., Yamada, T., Yamamoto, A., Yamanaka, K., Yamashina, S., Yamashiro, S., Yan, B., Yan, B., Yan, X., Yan, Z., Yanagi, Y., Yang, D.-S., Yang, J.-M., Yang, L., Yang, M., Yang, P.-M., Yang, P., Yang, Q., Yang, W., Yang, W.Y., Yang, X., Yang, Y., Yang, Y., Yang, Z., Yang, Z., Yao, M.-C., Yao, P.J., Yao, X., Yao, Z., Yao, Z., Yasui, L.S., Ye, M., Yedvobnick, B., Yeganeh, B., Yeh, E.S., Yeyati, P.L., Yi, F., Yi, L., Yin, X.-M., Yip, C.K., Yoo, Y.-M., Yoo, Y.H., Yoon, S.-Y., Yoshida, K.-I., Yoshimori, T., Young, K.H., Yu, H., Yu, J.J., Yu, J.-T., Yu, J., d Yu, L. and Yu, W.H. and Yu, X.-F., Yu, Z., Yuan, J., Yuan, Z.-M., nd Yue, B.Y.J.T., Yue, J., Yue, Z., Zacks, D.N., Zacksenhaus, E., Zaffaroni, N., Zaglia, T., Zakeri, Z., Zecchini, V., Zeng, J., Zeng, M., Zeng, Q., Zervos, A.S., Zhang, D.D., Zhang, F., Zhang, G., Zhang, G.-C., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J.-P., Zhang, L., Zhang, L., Zhang, L., Zhang, M.-Y., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhao, M., Zhao, W.-L., Zhao, X., Zhao, Y.G., Zhao, Y., Zhao, Y., Zhao, Y.-X., Zhao, Z., Zhao, Z.J., Zheng, D., Zheng, X.-L., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, G.-Z., Zhou, G., Zhou, H., Zhou, S.-F., Zhou, X.-J., Zhu, H., Zhu, H., Zhu, W.-G., Zhu, W., nd Zhu, X.-F., Zhu, Y., Zhuang, S.-M., Zhuang, X., Ziparo, E., Zois, C.E., Zoladek, T., Zong, W.-X., Zorzano, A., Zughaier, S.M.

    Autophagy   12 ( 1 )   2016

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    DOI： 10.1080/15548627.2015.1100356

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  • Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

    Sin, J., Andres, A.M., Taylo R., D.J.R., Weston, T., Hiraumi, Y., Stotland, A., Kim, B.J., Huang, C., Doran, K.S., Gottlieb, R.A.

    Autophagy   12 ( 2 )   2016

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    DOI： 10.1080/15548627.2015.1115172

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  • Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy

    Queliconi, B.B., Kowaltowski, A.J., Gottlieb, R.A.

    Plos One   11 ( 12 )   2016

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    DOI： 10.1371/journal.pone.0167678

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  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Arozena, A.A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., Adhihetty, P.J., Adler, S.G., Agam, G., Agarwal, R., Aghi, M.K., Agnello, M., Agostinis, P., Aguilar, P.V., Aguirre-Ghiso, J., Airoldi, E.M., Ait-Si-Ali, S., Akematsu, T., Akporiaye, E.T., Al-Rubeai, M., Albaiceta, G.M., Albanese, C., Albani, D., Albert, M.L., Aldudo, J., Alg{\"u}l, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E.S., Alonso, C., Altan-Bonnet, N., Altieri, D.C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A.O., Amessou, M., Amon, A., An, Z., Anania, F.A., Andersen, S.U., Andley, U.P., Andreadi, C.K., Andrieu-Abadie, N., Anel, A., Ann, D.K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A.R., Armstrong, J.L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S.S., Atkin, J.D., Attardi, L.D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M.L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J.M., Bae, D.-H., Bae, J.-S., Bae, O.-N., Bae, S.H., Baehrecke, E.H., Baek, S.-H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X.-Y., Bailly, Y., Balaji, K.N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., B{\'a}nhegyi, G., Bao, H., Barbeau, B., Barrachina, M.D., Barreiro, E., Bartel, B., Bartolom{\'e}, A., Bassham, D.C., Bassi, M.T., Bast, R.C., Basu, A., Batista, M.T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B.L., Bayer, K.U., Beale, R., Beaulieu, J.-F., Beck, G.R., Becker, C., Beckham, J.D., B{\'e}dard, P.-A., Bednarski, P.J., Begley, T.J., Behl, C., Behrends, C., Behrens, G.M.N., Behrns, K.E., Bejarano, E., Belaid, A., Belleudi, F., B{\'e}nard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A.S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S.K., Biagosch, C., Bianchi, M.W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S.W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G.A., Blomhoff, H.K., Boada-Romero, E., B{\"o}ckler, S., Boes, M., Boesze-Battaglia, K., Boise, L.H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L.M., Botti, J., Bou, G., Bouch{\'e}, M., Bouchecareilh, M., Boucher, M.-J., Boulton, M.E., Bouret, S.G., Boya, P., Boyer-Guittaut, M., Bozhkov, P.V., Brady, N., Braga, V.M.M., Brancolini, C., Braus, G.H., Bravo-San-Pedro, J.M., Brennan, L.A., Bresnick, E.H., Brest, P., Bridges, D., Bringer, M.-A., Brini, M., Brito, G.C., Brodin, B., Brookes, P.S., Brown, E.J., Brown, K., Broxmeyer, H.E., Bruhat, A., Brum, P.C., Brumell, J.H., Brunetti-Pierri, N., Bryson-Richardson, R.J., Buch, S., Buchan, A.M., Budak, H., Bulavin, D.V., Bultman, S.J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R.E., Burmeister, M., B{\"u}tikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G.R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A.B., Caraglia, M., Cardinali, C., Cardoso, S.M., Carew, J.S., Carleton, L.A., Carlin, C.R., Carloni, S., Carlsson, S.R., Carmona-Gutierrez, D., Carneiro, L.A.M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A.I., Ce{\~n}a, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H.-J., Chagin, A.S., Chai, C.-Y., Chakrabarti, G., Chamilos, G., Chan, E.Y.W., Chan, M.T.V., Chandra, D., Chandra, P., Chang, C.-P., Chang, R.C.-C., Chang, T.Y., Chatham, J.C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M.E., Cheluvappa, R., Chen, C.-J., Chen, G., Chen, G.-C., Chen, G., Chen, H., Chen, J.W., Chen, J.-K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S.-D., Chen, S., Chen, S.S.-L., Chen, W., Chen, W.-J., Chen, W.Q., Chen, W., Chen, X., Chen, Y.-H., Chen, Y.-G., Chen, Y., Chen, Y., Chen, Y., Chen, Y.-J., Chen, Y.-Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C.H.K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C.H.A., Chevet, E., Chi, H.C., Chi, S.-G., Chiacchiera, F., Chiang, H.-L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L.-S., Chiong, M., Chiu, G.N.C., Cho, D.-H., Cho, S.-G., Cho, W.C., Cho, Y.-Y., Cho, Y.-S., Choi, A.M.K., Choi, E.-J., Choi, E.-K., Choi, J., Choi, M.E., Choi, S.-I., Chou, T.-F., Chouaib, S., Choubey, D., Choubey, V., Chow, K.-C., Chowdhury, K., Chu, C.T., Chuang, T.-H., Chun, T., Chung, H., Chung, T., Chung, Y.-L., Chwae, Y.-J., Cianfanelli, V., Ciarcia, R., Ciechomska, I.A., Ciriolo, M.R., Cirone, M., Claerhout, S., Clague, M.J., Claria, J., Clarke, P.G.H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E.M., Cocco, T., Codogno, P., Coers, J., Cohen, E.E.W., Colecchia, D., Coletto, L., Coll, N.S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K.L., Coombs, G.H., Cooper, C.D., Cooper, J.M., Coppens, I., Corasaniti, M.T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M.D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S.L., Coto-Montes, A., Cottet, S., Couve, E., Covey, L.R., Cowart, L.A., Cox, J.S., Coxon, F.P., Coyne, C.B., Cragg, M.S., Craven, R.J., Crepaldi, T., Crespo, J.L., Criollo, A., Crippa, V., Cruz, M.T., Cuervo, A.M., Cuezva, J.M., Cui, T., Cutillas, P.R., Czaja, M.J., Czyzyk-Krzeska, M.F., Dagda, R.K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K.N., Valle, L.D., Dalmasso, G., D{'}amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V.M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C.R., Davey, H.M., Davids, L.M., D{\'a}vila, D., Davis, R.J., Dawson, T.M., Dawson, V.L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, R.C.B.Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G.R.Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J.-P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D.P., Delage-Mourroux, R., Delbridge, L.M.D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C.J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T.P., Devenish, R.J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., Di Antonio, A., D{\'i}az-Araya, G., D{\'i}az-Laviada, I., Diaz-Meco, M.T., Diaz-Nido, J., Dickey, C.A., Dickson, R.C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S.P., Ding, C., Ding, W.-X., Ding, Z., Dini, L., Distler, J.H.W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R.C.J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X.C., Dong, X., Dong, Z., Donohue, T.M., Donohue-Jr, T.M., Doran, K.S., D{'}orazi, G., Dorn, G.W., Dosenko, V., Dridi, S., Drucker, L., Du, J., Du, L.-L., Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V.K., Duchen, M.R., Duchosal, M.A., Duez, H., Dugail, I., Dumit, V.I., Duncan, M.C., Dunlop, E.A., Dunn, W.A., Dupont, N., Dupuis, L., Dur{\'a}n, R.V., Durcan, T.M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C.L., Edinger, A.L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N.T., El-Deiry, W.S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C.J.H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A.-M., Engelender, S., Enserink, J.M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J.L., Erman, A., Escalante, R., Eskelinen, E.-L., Espert, L., Esteban-Mart{\'i}nez, L., Evans, T.J., Fabri, M., Fabrias, G., Fabrizi, C., Facchiano, A., F?rgeman, N.J., Faggioni, A., Fairlie, W.D., Fan, C., Fan, D., Fan, J., Fang, S., Fanto, M., Fanzani, A., Farkas, T., Faure, M., Favier, F.B., Fearnhead, H., Federici, M., Fei, E., Felizardo, T.C., Feng, H., Feng, Y., Feng, Y., Ferguson, T.A., Fern{\'a}ndez, ?.F., Fernandez-Barrena, M.G., Fernandez-Checa, J.C., Fern{\'a}ndez-L{\'o}pez, A., Fernandez-Zapico, M.E., Feron, O., Ferraro, E., Ferreira-Halder, C.V., Fesus, L., Feuer, R., Fiesel, F.C., Filippi-Chiela, E.C., Filomeni, G., Fimia, G.M., Fingert, J.H., Finkbeiner, S., Finkel, T., Fiorito, F., Fisher, P.B., Flajolet, M., Flamigni, F., Florey, O., Florio, S., Floto, R.A., Folini, M., Follo, C., Fon, E.A., Fornai, F., Fortunato, F., Fraldi, A., Franco, R., Francois, A., Fran?ois, A., Frankel, L.B., Fraser, I.D.C., Frey, N., Freyssenet, D.G., Frezza, C., Friedman, S.L., Frigo, D.E., Fu, D., Fuentes, J.M., Fueyo, J., Fujitani, Y., Fujiwara, Y., Fujiya, M., Fukuda, M., Fulda, S., Fusco, C., Gabryel, B., Gaestel, M., Gailly, P., Gajewska, M., Galadari, S., Galili, G., Galindo, I., Galindo, M.F., Galliciotti, G., Galluzzi, L., Galluzzi, L., Galy, V., Gammoh, N., Gandy, S., Ganesan, A.K., Ganesan, S., Ganley, I.G., Gannag{\'e}, M., Gao, F.-B., Gao, F., Gao, J.-X., Nannig, L.G., V{\'e}scovi, E.G., Garcia-Mac{\'i}a, M., Garcia-Ruiz, C., Garg, A.D., Garg, P.K., Gargini, R., Gassen, N.C., Gatica, D., Gatti, E., Gavard, J., Gavathiotis, E., Ge, L., Ge, P., Ge, S., Gean, P.-W., Gelmetti, V., Genazzani, A.A., Geng, J., Genschik, P., Gerner, L., Gestwicki, J.E., Gewirtz, D.A., Ghavami, S., Ghigo, E., Ghosh, D., Giammarioli, A.M., Giampieri, F., Giampietri, C., Giatromanolaki, A., Gibbings, D.J., Gibellini, L., Gibson, S.B., Ginet, V., Giordano, A., Giorgini, F., Giovannetti, E., Girardin, S.E., Gispert, S., Giuliano, S., Gladson, C.L., Glavic, A., Gleave, M., Godefroy, N., Gogal, R.M., Gokulan, K., Goldman, G.H., Goletti, D., Goligorsky, M.S., Gomes, A.V., Gomes, L.C., Gomez, H., Gomez-Manzano, C., G{\'o}mez-S{\'a}nchez, R., Gon?alves, D.A.P., Goncu, E., Gong, Q., Gongora, C., Gonzalez, C.B., Gonzalez-Alegre, P., Gonzalez-Cabo, P., Gonz{\'a}lez-Polo, R.A., Goping, I.S., Gorbea, C., Gorbunov, N.V., Goring, D.R., Gorman, A.M., Gorski, S.M., Goruppi, S., Goto-Yamada, S., Gotor, C., Gottlieb, R.A., Gozes, I., Gozuacik, D., Graba, Y., Graef, M., Granato, G.E., Grant, G.D., Grant, S., Gravina, G.L., Green, D.R., Greenhough, A., Greenwood, M.T., Grimaldi, B., Gros, F., Grose, C., Groulx, J.-F., Gruber, F., Grumati, P., Grune, T., Guan, J.-L., Guan, K.-L., Guerra, B., Guillen, C., Gulshan, K., Gunst, J., Guo, C., Guo, L., Guo, M., Guo, W., Guo, X.-G., Gust, A.A., Gustafsson, ?, B, Gutierrez, E., Gutierrez, M.G., Gwak, H.-S., Haas, A., Haber, J.E., Hadano, S., Hagedorn, M., Hahn, D.R., Halayko, A.J., Hamacher-Brady, A., Hamada, K., Hamai, A., Hamann, A., Hamasaki, M., Hamer, I., Hamid, Q., Hammond, E.M., Han, F., Han, W., Handa, J.T., Hanover, J.A., Hansen, M., Harada, M., Harhaji-Trajkovic, L., Harper, J.W., Harrath, A.H., Harris, A.L., Harris, J., Hasler, U., Hasselblatt, P., Hasui, K., Hawley, R.G., Hawley, T.S., He, C., and He, C.Y., and He, F. and He, G. and He, R.-R. and He, X.-H., and He, Y.-W., He, Y.-Y., Heath, J.K., H{\'e}bert, M.-J., Heinzen, R.A., Helgason, G.V., Hensel, M., Henske, E.P., Her, C., Herman, P.K., Hern{\'a}ndez, A., Hernandez, C., Hern{\'a}ndez-Tiedra, S., Hetz, C., Hiesinger, P.R., Higaki, K., Hilfiker, S., Hill, B.G., Hill, J.A., Hill, W.D., Hino, K., Hofius, D., Hofman, P., H{\"o}glinger, G.U., H{\"o}hfeld, J., Holz, M.K., Hong, Y., Hood, D.A., Hoozemans, J.J.M., Hoppe, T., Hsu, C., Hsu, C.-Y., Hsu, L.-C., Hu, D., Hu, G., Hu, H.-M., Hu, H., Hu, M.C., Hu, Y.-C., Hu, Z.-W., Hua, F., Hua, Y., Huang, C., Huang, H.-L., Huang, K.-H., Huang, K.-Y., Huang, S., Huang, S., Huang, W.-P., Huang, Y.-R., Huang, Y., Huang, Y., Huber, T.B., Huebbe, P., Huh, W.-K., Hulmi, J.J., Hur, G.M., Hurley, J.H., Husak, Z., Hussain, S.N.A., Hussain, S., Hwang, J.J., Hwang, S., Hwang, T.I.S., Ichihara, A., Imai, Y., Imbriano, C., Inomata, M., Into, T., Iovane, V., Iovanna, J.L., Iozzo, R.V., Ip, N.Y., Irazoqui, J.E., Iribarren, P., Isaka, Y., Isakovic, A.J., Ischiropoulos, H., Isenberg, J.S., Ishaq, M., Ishida, H., Ishii, I., Ishmael, J.E., Isidoro, C., Isobe, K.-I., Isono, E., Issazadeh-Navikas, S., Itahana, K., Itakura, E., Ivanov, A.I., Iyer, A.K.V., Izquierdo, J.M., Izumi, Y., Izzo, V., J, a, a}ttel{\"a}, M., Jaber, N., Jackson, D.J., Jackson, W.T., Jacob, T.G., Jacques, T.S., Jagannath, C., Jain, A., Jana, N.R., Jang, B.K., Jani, A., Janji, B., Jannig, P.R., Jansson, P.J., Jean, S., Jendrach, M., Jeon, J.-H., Jessen, N., Jeung, E.-B., Jia, K., Jia, L., Jiang, H., Jiang, H., Jiang, L., Jiang, T., Jiang, X., Jiang, X., Jiang, Y., Jiang, Y., Jim{\'e}nez, A., Jin, C., Jin, H., Jin, L., Jin, M., Jin, S., Jinwal, U.K., Jo, E.-K., Johansen, T., Johnson, D.E., Johnson, G.V.W., Johnson, J.D., Jonasch, E., Jones, C., Joosten, L.A.B., Jordan, J., Joseph, A.-M., Joseph, B., Joubert, A.M., Ju, D., Ju, J., Juan, H.-F., Juenemann, K., Juh{\'a}sz, G., Jung, H.S., Jung, J.U., Jung, Y.-K., Jungbluth, H., Justice, M.J., Jutten, B., Kaakoush, N.O., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaeffer, B., K?gedal, K., Kahana, A., Kajimura, S., Kakhlon, O., Kalia, M., Kalvakolanu, D.V., Kamada, Y., Kambas, K., Kaminskyy, V.O., Kampinga, H.H., Kandouz, M., Kang, C., Kang, R., Kang, T.-C., Kanki, T., Kanneganti, T.-D., Kanno, H., Kanthasamy, A.G., Kantorow, M., Kaparakis-Liaskos, M., Kapuy, O., Karantza, V., Karim, M.R., Karmakar, P., Kaser, A., Kaushik, S., Kawula, T., Kaynar, A.M., nd Ke, P.-Y., Ke, Z.-J., Kehrl, J.H., Keller, K.E., Kemper, J.K., Kenworthy, A.K., Kepp, O., Kern, A., Kesari, S., Kessel, D., Ketteler, R., Kettelhut, I.C., Khambu, B., Khan, M.M., Khandelwal, V.K.M., Khare, S., Kiang, J.G., Kiger, A.A., Kihara, A., Kim, A.L., Kim, C.H., Kim, D.R., Kim, D.-H., Kim, E.K., Kim, H.Y., Kim, H.-R., Kim, J.-S., Kim, J.H., Kim, J.C., Kim, J.H., Kim, K.W., Kim, M.D., Kim, M.-M., Kim, P.K., Kim, S.W., Kim, S.-Y., Kim, Y.-S., Kim, Y., Kimchi, A., Kimmelman, A.C., Kimura, T., King, J.S., Kirkegaard, K., Kirkin, V., Kirshenbaum, L.A., Kishi, S., Kitajima, Y., Kitamoto, K., Kitaoka, Y., Kitazato, K., Kley, R.A., Klimecki, W.T., Klinkenberg, M., Klucken, J., Kn?velsrud, H., Knecht, E., Knuppertz, L., Ko, J.-L., Kobayashi, S., Koch, J.C., Koechlin-Ramonatxo, C., Koenig, U., Koh, Y.H., K{\"o}hler, K., Kohlwein, S.D., Koike, M., Komatsu, M., Kominami, E., Kong, D., Kong, H.J., Konstantakou, E.G., Kopp, B.T., Korcsmaros, T., Korhonen, L., Korolchuk, V.I., Koshkina, N.V., Kou, Y., Koukourakis, M.I., Koumenis, C., Kov{\'a}cs, A.L., Kov{\'a}cs, T., Kovacs, W.J., Koya, D., Kraft, C., Krainc, D., Kramer, H., Kravic-Stevovic, T., Krek, W., Kretz-Remy, C., Krick, R., Krishnamurthy, M., Kriston-Vizi, J., Kroemer, G., Kruer, M.C., Kruger, R., Ktistakis, N.T., Kuchitsu, K., Kuhn, C., Kumar, A.P., Kumar, A., Kumar, A., Kumar, D., Kumar, D., Kumar, R., Kumar, S., Kundu, M., Kung, H.-J., Kuno, A., Kuo, S.-H., Kuret, J., Kurz, T., Kwok, T., Kwon, T.K., Kwon, Y.T., Kyrmizi, I., La Spada, A.R., Lafont, F., Lahm, T., Lakkaraju, A., Lam, T., Lamark, T., Lancel, S., Landowski, T.H., Lane, D.J.R., Lane, J.D., Lanzi, C., Lapaquette, P., Lapierre, L.R., Laporte, J., Laukkarinen, J., Laurie, G.W., Lavandero, S., Lavie, L., Lavoie, M.J., d Law, B.Y.K., and Law, H.K.-W., Law, K.B., Layfield, R., Lazo, P.A., Le Cam, L., Le Roch, K.G., Le Stunff, H., Leardkamolkarn, V., Lecuit, M., d Lee, B.-H., and Lee, C.-H., Lee, E.F., Lee, G.M., Lee, H.-J., Lee, H., Lee, J.K., Lee, J., Lee, J.-H., Lee, J.H., Lee, M., and Lee, M.-S. and Lee, P.J. and Lee, S.W. and Lee, S.-J., and Lee, S.-J., and Lee, S.Y., and Lee, S.H., and Lee, S.S., a, d Lee, S.-J., Lee, S., d Lee, Y.-R., Lee, Y.J., Lee, Y.H., Leeuwenburgh, C., Lefort, S., Legouis, R., Lei, J., Lei, Q.-Y., Leib, D.A., Leibowitz, G., Lekli, I., Lemaire, S.D., Lemasters, J.J., Lemberg, M.K., Lemoine, A., Leng, S., Lenz, G., Lenzi, P., Lerman, L.O., Barbato, D.L., Leu, J.I.J., Leung, H.Y., Levine, B., Lewis, P.A., Lezoualch, F., Li, C., Li, F., Li, F.-J., Li, J., Li, K., Li, L., Li, M., Li, Q., Li, R., Li, S., Li, W., Li, X., Li, Y., Lian, J., Liang, C., Liang, Q., Liao, Y., Liberal, J., Liberski, P.P., Lie, P., Lieberman, A.P., Lim, H.J., Lim, K.-L., Lim, K., Lima, R.T., Lin, C.-S., Lin, C.-F., Lin, F., Lin, F., Lin, F.-C., Lin, K., Lin, K.-H., Lin, P.-H., Lin, T., Lin, W.-W., Lin, Y.-S., Lin, Y., Linden, R., Lindholm, D. and L., qvist, L.M., Lingor, P., Linkermann, A., Liotta, L.A., Lipinski, M.M., Lira, V.A., Lisanti, M.P., Liton, P.B., Liu, B., Liu, C., Liu, C.-F., Liu, F., Liu, H.-J., Liu, J., Liu, J.-J., Liu, J.-L., Liu, K., Liu, L., Liu, L., Liu, Q., Liu, R.-Y., Liu, S., Liu, S., Liu, W., Liu, X.-D., Liu, X., Liu, X.-H., Liu, X., Liu, X., Liu, X., Liu, Y., Liu, Y., Liu, Z., Liu, Z., Liuzzi, J.P., Lizard, G., Ljujic, M., Lodhi, I.J., Logue, S.E., Lokeshwar, B.L., Long, Y.C., Lonial, S., Loos, B., L{\'o}pez-Ot{\'i}n, C., L{\'o}pez-Vicario, C., Lorente, M., Lorenzi, P.L., L{\~o}rincz, P., Los, M., Lotze, M.T., Lovat, P.E., Lu, B., Lu, B., Lu, J., Lu, Q., Lu, S.-M., Lu, S., Lu, Y., Luciano, F., Luckhart, S., Lucocq, J.M., Ludovico, P., Lugea, A., Lukacs, N.W., Lum, J.J., Lund, A.H., Luo, H., Luo, J., Luo, S., Luparello, C., Lyons, T., Ma, J., Ma, Y., Ma, Y., Ma, Z., Machado, J., Machado-Santelli, G.M., Macian, F., MacIntosh, G.C., MacKeigan, J.P., Macleod, K.F., MacMicking, J.D., MacMillan-Crow, L.A., Madeo, F., Madesh, M., Madrigal-Matute, J., Maeda, A., Maeda, T., Maegawa, G., Maellaro, E., Maes, H., Magari{\~n}os, M., Maiese, K., Maiti, T.K., Maiuri, L., Maiuri, M.C., Maki, C.G., Malli, R., Malorni, W., Maloyan, A., Mami-Chouaib, F., Man, N., Mancias, J.D., Mandelkow, E.-M., Mandell, M.A., Manfredi, A.A., Mani{\'e}, S.N., Manzoni, C., Mao, K., Mao, Z., Mao, Z.-W., Marambaud, P., Marconi, A.M., Marelja, Z., Marfe, G., Margeta, M., Margittai, E., Mari, M., Mariani, F.V., Marin, C., Marinelli, S., Mari{\~n}o, G., Markovic, I., Marquez, R., Martelli, A.M., Martens, S., Martin, K.R., Martin, S.J., Martin, S., Martin-Acebes, M.A., Mart{\'i}n-Sanz, P., d Martin, Mari, C., Martinet, W., Martinez, J., Martinez-Lopez, N., Martinez-Outschoorn, U., Mart{\'i}nez-Vel{\'a}zquez, M., Martinez-Vicente, M., Martins, W.K., Mashima, H., Mastrianni, J.A., Matarese, G., Matarrese, P., Mateo, R., Matoba, S., Matsumoto, N., Matsushita, T., Matsuura, A., Matsuzawa, T., Mattson, M.P., Matus, S., Maugeri, N., Mauvezin, C., Mayer, A., Maysinger, D., Mazzolini, G.D., McBrayer, M.K., McCall, K., McCormick, C., McInerney, G.M., McIver, S.C., McKenna, S., McMahon, J.J., McNeish, I.A., Mechta-Grigoriou, F., Medema, J.P., Medina, D.L., Megyeri, K., Mehrpour, M., Mehta, J.L., Mei, Y., Meier, U.-C., Meijer, A.J., Mel{\'e}ndez, A., Melino, G., Melino, S., de Melo, E.J.T., Mena, M.A., Meneghini, M.D., Menendez, J.A., Menezes, R., Meng, L., Meng, L.-H., Meng, S., Menghini, R., Menko, A.S., Menna-Barreto, R.F.S., Menon, M.B., Meraz-R{\'i}os, M.A., Merla, G., Merlini, L., Merlot, A.M., Meryk, A., Meschini, S., Meyer, J.N., Mi, M.-T., Miao, C.-Y., Micale, L., Michaeli, S., Michiels, C., Migliaccio, A.R., Mihailidou, A.S., Mijaljica, D., Mikoshiba, K., Milan, E., Miller-Fleming, L., Mills, G.B., Mills, I.G., Minakaki, G., Minassian, B.A., Ming, X.-F., Minibayeva, F., Minina, E.A., Mintern, J.D., Minucci, S., Miranda-Vizuete, A., Mitchell, C.H., Miyamoto, S., Miyazawa, K., Mizushima, N., Mnich, K., Mograbi, B., Mohseni, S., Moita, L.F., Molinari, M., Molinari, M., M?ller, A.B., Mollereau, B., Mollinedo, F., Mongillo, M., Monick, M.M., Montagnaro, S., Montell, C., Moore, D.J., Moore, M.N., Mora-Rodriguez, R., Moreira, P.I., Morel, E., Morelli, M.B., Moreno, S., Morgan, M.J., Moris, A., Moriyasu, Y., Morrison, J.L., Morrison, L.A., Morselli, E., Moscat, J., Moseley, P.L., Mostowy, S., Motori, E., Mottet, D., Mottram, J.C., Moussa, C.E.-H., Mpakou, V.E., Mukhtar, H., Levy, J.M.M., Muller, S., Mu{\~n}oz-Moreno, R., Mu{\~n}oz-Pinedo, C., M{\"u}nz, C., Murphy, M.E., Murray, J.T., Murthy, A., Mysorekar, I.U., Nabi, I.R., Nabissi, M., Nader, G.A., Nagahara, Y., Nagai, Y., Nagata, K., Nagelkerke, A., Nagy, P., Naidu, S.R., Nair, S., Nakano, H., Nakatogawa, H., Nanjundan, M., Napolitano, G., Naqvi, N.I., Nardacci, R., Narendra, D.P., Narita, M., Nascimbeni, A.C., Natarajan, R., Navegantes, L.C., Nawrocki, S.T., Nazarko, T.Y., Nazarko, V.Y., Neill, T., Neri, L.M., Netea, M.G., Netea-Maier, R.T., Neves, B.M., Ney, P.A., Nezis, I.P., Nguyen, H.T.T., Nguyen, H.P., Nicot, A.-S., Nilsen, H., Nilsson, P., Nishimura, M., Nishino, I., Niso-Santano, M., Niu, H., Nixon, R.A., Njar, V.C.O., Noda, T., Noegel, A.A., Nolte, E.M., Norberg, E., Norga, K.K., Noureini, S.K., Notomi, S., Notterpek, L., Nowikovsky, K., Nukina, N., N{\"u}rnberger, T., O{'}donnell, V.B., O{'}donovan, T., O{'}dwyer, P.J., Oehme, I., Oeste, C.L., Ogawa, M., Ogretmen, B., Ogura, Y., Oh, Y.J., Ohmuraya, M., Ohshima, T., Ojha, R., Okamoto, K., Okazaki, T., Oliver, F.J., Ollinger, K., Olsson, S., Orban, D.P., Ordonez, P., Orhon, I., Orosz, L., O{'}rourke, E.J., Orozco, H., Ortega, A.L., Ortona, E., Osellame, L.D., Oshima, J., Oshima, S., Osiewacz, H.D., Otomo, T., Otsu, K., Ou, J.-H.J., Outeiro, T.F., Ouyang, D.-Y., Ouyang, H., Overholtzer, M., Ozbun, M.A., Ozdinler, P.H., Ozpolat, B., Pacelli, C., Paganetti, P., Page, G., Pages, G., Pagnini, U., Pajak, B., Pak, S.C., Pakos-Zebrucka, K., Pakpour, N., Palkov{\'a}, Z., Palladino, F., Pallauf, K., Pallet, N., Palmieri, M., Paludan, S.R., Palumbo, C., Palumbo, S., Pampliega, O., Pan, H., Pan, W., Panaretakis, T., Pandey, A., Pantazopoulou, A., Papackova, Z., Papademetrio, D.L., Papassideri, I., Papini, A., Parajuli, N., Pardo, J., Parekh, V.V., Parenti, G., Park, J.-I., Park, J., Park, O.K., Parker, R., Parlato, R., Parys, J.B., Parzych, K.R., Pasquet, J.-M., Pasquier, B., Pasumarthi, K.B.S., Patterson, C., Pattingre, S., Pattison, S., Pause, A., Pavenst{\"a}dt, H., Pavone, F., Pedrozo, Z., Pe{\~n}a, F.J., Pe, n}alva, M.A., Pende, M., Peng, J., Penna, F., Penninger, J.M., Pensalfini, A., Pepe, S., Pereira, G.J.S., Pereira, P.C., de la Cruz, V.P., P{\'e}rez-P{\'e}rez, M.E., P{\'e}rez-Rodr{\'i}guez, D., P{\'e}rez-Sala, D., Perier, C., Perl, A., Perlmutter, D.H., Perrotta, I., Pervaiz, S., Pesonen, M., Pessin, J.E., Peters, G.J., Petersen, M., Petrache, I., Petrof, B.J., Petrovski, G., Phang, J.M., Piacentini, M., Pierdominici, M., Pierre, P., Pierrefite-Carle, V., Pietrocola, F., Pimentel-Mui{\~n}os, F.X., Pinar, M., Pineda, B., Pinkas-Kramarski, R., Pinti, M., Pinton, P., Piperdi, B., Piret, J.M., Platanias, L.C., Platta, H.W., Plowey, E.D., P{\"o}ggeler, S., Poirot, M., Pol?ic, P., Poletti, A., Poon, A.H., Popelka, H., Popova, B., Poprawa, I., Poulose, S.M., Poulton, J., Powers, S.K., Powers, T., Pozuelo-Rubio, M., Prak, K., Prange, R., Prescott, M., Priault, M., Prince, S., Proia, R.L., Proikas-Cezanne, T., Prokisch, H., Promponas, V.J., Przyklenk, K., Puertollano, R., Pugazhenthi, S., Puglielli, L., Pujol, A., Puyal, J., Pyeon, D., Qi, X., Qian, W.-B., Qin, Z.-H., Qiu, Y., Qu, Z., Quadrilatero, J., Quinn, F., Raben, N., Rabinowich, H., Radogna, F., Ragusa, M.J., Rahmani, M., Raina, K., Ramanadham, S., Ramesh, R., Rami, A., Randall-Demllo, S., Randow, F., Rao, H., Rao, V.A., Rasmussen, B.B., Rasse, T.M., Ratovitski, E.A., Rautou, P.-E., Ray, S.K., Razani, B., Reed, B.H., Reggiori, F., Rehm, M., Reichert, A.S., Rein, T., Reiner, D.J., Reits, E., Ren, J., Ren, X., Renna, M., Reusch, J.E.B., Revuelta, J.L., Reyes, L., Rezaie, A.R., Richards, R.I., Richardson, R., Richetta, C., Riehle, M.A., Rihn, B.H., Rikihisa, Y., Riley, B.E., Rimbach, G., Rippo, M.R., Ritis, K., Rizzi, F., Rizzo, E., Roach, P.J., Robbins, J., Roberge, M., Roca, G., Roccheri, M.C., Rocha, S., Rodrigues, C.M.P., Rodr{\'i}guez, C.I., de Cordoba, S.R., Rodriguez-Muela, N., Roelofs, J., Rogov, V.V., Rohn, T.T., Rohrer, B., Romanelli, D., Romani, L., Romano, P.S., Roncero, M.I.G., Rosa, J.L., Rosello, A., Rosen, K.V., Rosenstiel, P., Rost-Roszkowska, M., Roth, K.A., Rou{\'e}, G., Rouis, M., Rouschop, K.M., Ruan, D.T., Ruano, D., Rubinsztein, D.C., Rucker, E.B., Rudich, A., Rudolf, E., Rudolf, R., Ruegg, M.A., Ruiz-Roldan, C., Ruparelia, A.A., Rusmini, P., Russ, D.W., Russo, G.L., Russo, G., Russo, R., Rusten, T.E., Ryabovol, V., Ryan, K.M., Ryter, S.W., Sabatini, D.M., Sacher, M., Sachse, C., Sack, M.N., Sadoshima, J., Saftig, P., Sagi-Eisenberg, R., Sahni, S., Saikumar, P., Saito, T., Saitoh, T., Sakakura, K., Sakoh-Nakatogawa, M., Sakuraba, Y., Salazar-Roa, M., Salomoni, P., Saluja, A.K., Salvaterra, P.M., Salvioli, R., Samali, A., Sanchez, A.M.J., S{\'a}nchez-Alc{\'a}zar, J.A., Sanchez-Prieto, R., Sandri, M., Sanjuan, M.A., Santaguida, S., Santambrogio, L., Santoni, G., Dos Santos, C.N., Saran, S., Sardiello, M., Sargent, G., Sarkar, P., Sarkar, S., Sarrias, M.R., Sarwal, M.M., Sasakawa, C., Sasaki, M., Sass, M., Sato, K., Sato, M., Satriano, J., Savaraj, N., Saveljeva, S., Schaefer, L., Schaible, U.E., Scharl, M., Schatzl, H.M., Schekman, R., Scheper, W., Schiavi, A., Schipper, H.M., Schmeisser, H., Schmidt, J., Schmitz, I., Schneider, B.E., Schneider, E.M., Schneider, J.L., Schon, E.A., Sch{\"o}nenberger, M.J., Sch{\"o}nthal, A.H., Schorderet, D.F., Schr{\"o}der, B., Schuck, S., Schulze, R.J., Schwarten, M., Schwarz, T.L., Sciarretta, S., Scotto, K., Scovassi, A.I., Screaton, R.A., Screen, M., Seca, H., Sedej, S., Segatori, L., Segev, N., Seglen, P.O., Segu{\'i}-Simarro, J.M., Segura-Aguilar, J., Seiliez, I., Seki, E., Sell, C., Semenkovich, C.F., Semenza, G.L., Sen, U., Serra, A.L., Serrano-Puebla, A., Sesaki, H., Setoguchi, T., Settembre, C., Shacka, J.J., Shajahan-Haq, A.N., Shapiro, I.M., Sharma, S., She, H., Shen, C.-K.J., Shen, C.-C., Shen, H.-M., Shen, S., Shen, W., Sheng, R., Sheng, X., Sheng, Z.-H., Shepherd, T.G., Shi, J., Shi, Q., Shi, Q., Shi, Y., Shibutani, S., Shibuya, K., Shidoji, Y., Shieh, J.-J., Shih, C.-M., Shimada, Y., Shimizu, S., Shin, D.W., Shinohara, M.L., Shintani, M., Shintani, T., Shioi, T., Shirabe, K., Shiri-Sverdlov, R., Shirihai, O., Shore, G.C., Shu, C.-W., Shukla, D., Sibirny, A.A., Sica, V., Sigurdson, C.J., Sigurdsson, E.M., Sijwali, P.S., Sikorska, B., Silveira, W.A., Silvente-Poirot, S., Silverman, G.A., Simak, J., Simmet, T., Simon, A.K., Simon, H.-U., Simone, C., Simons, M., Simonsen, A., Singh, R., Singh, S.V., Singh, S.K., Sinha, D., Sinha, S., Sinicrope, F.A., Sirko, A., Sirohi, K., Sishi, B.J.N., Sittler, A., Siu, P.M., Sivridis, E., Skwarska, A., Slack, R., Slaninov{\'a}, I., Slavov, N., Smaili, S.S., Smalley, K.S.M., Smith, D.R., Soenen, S.J., Soleimanpour, S.A., Solhaug, A., Somasundaram, K., Son, J.H., Sonawane, A., Song, C., Song, F., Song, H.K., Song, J.-X., Song, W., Soo, K.Y., Sood, A.K., Soong, T.W., Soontornniyomkij, V., Sorice, M., Sotgia, F., Soto-Pantoja, D.R., Sotthibundhu, A., Sousa, M.J., Spaink, H.P., Span, P.N., Spang, A., Sparks, J.D., Speck, P.G., Spector, S.A., Spies, C.D., Springer, W., Clair, D.S., Stacchiotti, A., Staels, B., Stang, M.T., Starczynowski, D.T., Starokadomskyy, P., Steegborn, C., Steele, J.W., Stefanis, L., Steffan, J., Stellrecht, C.M., Stenmark, H., Stepkowski, T.M., Stern, S.T., Stevens, C., Stockwell, B.R., Stoka, V., Storchova, Z., Stork, B., Stratoulias, V., Stravopodis, D.J., Strnad, P., Strohecker, A.M., Str{\"o}m, A.-L., Stromhaug, P., Stulik, J., Su, Y.-X., Su, Z., Subauste, C.S., Subramaniam, S., Sue, C.M., Suh, S.W., Sui, X., Sukseree, S., Sulzer, D., Sun, F.-L., Sun, J., Sun, J., Sun, S.-Y., Sun, Y., Sun, Y., Sun, Y., Sundaramoorthy, V., Sung, J., Suzuki, H., Suzuki, K., Suzuki, N., Suzuki, T., Suzuki, Y.J., Swanson, M.S., Swanton, C., Sw{\"a}rd, K., Swarup, G., Sweeney, S.T., Sylvester, P.W., Szatmari, Z., Szegezdi, E., Szlosarek, P.W., Taegtmeyer, H., Tafani, M., Taillebourg, E., Tait, S.W.G., Takacs-Vellai, K., Takahashi, Y., Tak{\'a}ts, S., Takemura, G., Takigawa, N., Talbot, N.J., Tamagno, E., Tamburini, J., Tan, C.-P., Tan, L., Tan, M.L., Tan, M., Tan, Y.-J., Tanaka, K., Tanaka, M., Tang, D., Tang, D., Tang, G., Tanida, I., Tanji, K., Tannous, B.A., Tapia, J.A., Tasset-Cuevas, I., Tatar, M., Tavassoly, I., Tavernarakis, N., Taylor, A., Taylor, G.S., Taylor, G.A., Taylor, J.P., Taylor, M.J., Tchetina, E.V., Tee, A.R., Teixeira-Clerc, F., Telang, S., Tencomnao, T., Teng, B.-B., Teng, R.-J., Terro, F., Tettamanti, G., Theiss, A.L., Theron, A.E., Thomas, K.J., Thom{\'e}, M.P., Thomes, P.G., Thorburn, A., Thorner, J., Thum, T., Thumm, M., Thurston, T.L.M., Tian, L., Till, A., Ting, J.P.-Y., Titorenko, V.I., Toker, L., Toldo, S., Tooze, S.A., Topisirovic, I., Torgersen, M.L., Torosantucci, L., Torriglia, A., Torrisi, M.R., Tournier, C., Towns, R., Trajkovic, V., Travassos, L.H., Triola, G., Tripathi, D.N., Trisciuoglio, D., Troncoso, R., Trougakos, I.P., Truttmann, A.C., Tsai, K.-J., Tschan, M.P., Tseng, Y.-H., Tsukuba, T., Tsung, A., Tsvetkov, A.S., Tu, S., Tuan, H.-Y., Tucci, M., Tumbarello, D.A., Turk, B., Turk, V., Turner, R.F.B., Tveita, A.A., Tyagi, S.C., Ubukata, M., Uchiyama, Y., Udelnow, A., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Underwood, B.R., Ungermann, C., Ureshino, R.P., Ushioda, R., Uversky, V.N., Uzc{\'a}tegui, N.L., Vaccari, T., Vaccaro, M.I., V{\'a}chov{\'a}, L., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, E.M., Vallette, F., Valverde, A.M., Van den Berghe, G., Van Den, Bosch, L., van den Brink, G.R., van der Goot, F.G., van der Klei, I.J., van der Laan, L.J.W., van Doorn, W.G., van Egmond, M., van Golen, K.L., Van Kaer, L., Campagne, M.L., Vandenabeele, P., Vandenberghe, W., Vanhorebeek, I., Varela-Nieto, I., Vasconcelos, M.H., Vasko, R., Vavvas, D.G., Vega-Naredo, I., Velasco, G., Velentzas, A.D., Velentzas, P.D., Vellai, T., Vellenga, E., Vendelbo, M.H., Venkatachalam, K., Ventura, N., Ventura, S., Veras, P.S.T., Verdier, M., Vertessy, B.G., Viale, A., Vidal, M., Vieira, H.L.A., Vierstra, R.D., Vigneswaran, N., Vij, N., Vila, M., Villar, M., Villar, V.H., d, Villarroya, J., Vindis, C., Viola, G., Viscomi, M.T., Vitale, G., Vogl, D.T., Voitsekhovskaja, O.V., von Haefen, C., von Schwarzenberg, K., Voth, D.E., Vouret-Craviari, V., Vuori, K., Vyas, J.M., Waeber, C., Walker, C.L., Walker, M.J., Walter, J., Wan, L., Wan, X., Wang, B., Wang, C., Wang, C.-Y., Wang, C., Wang, C., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H.-J., Wang, H., Wang, H.-G., Wang, H., Wang, H.-D., Wang, J., Wang, J., Wang, M., Wang, M.-Q., Wang, P.-Y., Wang, P., Wang, R.C., Wang, S., Wang, T.-F., Wang, X., Wang, X.-J., Wang, X.-W., Wang, X., Wang, X., Wang, Y., Wang, Y., Wang, Y., Wang, Y.-J., Wang, Y., Wang, Y., Wang, Y.T., Wang, Y., Wang, Z.-N., Wappner, P., Ward, C., Ward, D.M.V., Warnes, G., Watada, H., Watanabe, Y., Watase, K., Weaver, T.E., Weekes, C.D., Wei, J., Weide, T., Weihl, C.C., Weindl, G., Weis, S.N., Wen, L., Wen, X., Wen, Y., Westermann, B., Weyand, C.M., White, A.R., White, E., Whitton, J.L., Whitworth, A.J., Wiels, J., Wild, F., Wildenberg, M.E., Wileman, T., Wilkinson, D.S., Wilkinson, S., Willbold, D., Williams, C., Williams, K., Williamson, P.R., Winklhofer, K.F., Witkin, S.S., Wohlgemuth, S.E., Wollert, T., Wolvetang, E.J., Wong, E., Wong, G.W., Wong, R.W., Wong, V.K.W., Woodcock, E.A., Wright, K.L., Wu, C., Wu, D., Wu, G.S., Wu, J., Wu, J., Wu, M., Wu, M., Wu, S., d Wu, W.K.K., Wu, Y., Wu, Z., Xavier, C.P.R., Xavier, R.J., Xia, G.-X., Xia, T., Xia, W., Xia, Y., Xiao, H., Xiao, J., Xiao, S., Xiao, W., Xie, C.-M., Xie, Z., Xie, Z., Xilouri, M., Xiong, Y., Xu, C., Xu, C., Xu, F., Xu, H., Xu, H., Xu, J., Xu, J., Xu, J., Xu, L., Xu, X., Xu, Y., Xu, Y., Xu, Z.-X., Xu, Z., Xue, Y., Yamada, T., Yamamoto, A., Yamanaka, K., Yamashina, S., Yamashiro, S., Yan, B., Yan, B., Yan, X., Yan, Z., Yanagi, Y., Yang, D.-S., Yang, J.-M., Yang, L., Yang, M., Yang, P.-M., Yang, P., Yang, Q., Yang, W., Yang, W.Y., Yang, X., Yang, Y., Yang, Y., Yang, Z., Yang, Z., Yao, M.-C., Yao, P.J., Yao, X., Yao, Z., Yao, Z., Yasui, L.S., Ye, M., Yedvobnick, B., Yeganeh, B., Yeh, E.S., Yeyati, P.L., Yi, F., Yi, L., Yin, X.-M., Yip, C.K., Yoo, Y.-M., Yoo, Y.H., Yoon, S.-Y., Yoshida, K.-I., Yoshimori, T., Young, K.H., Yu, H., Yu, J.J., Yu, J.-T., Yu, J., d Yu, L. and Yu, W.H. and Yu, X.-F., Yu, Z., Yuan, J., Yuan, Z.-M., nd Yue, B.Y.J.T., Yue, J., Yue, Z., Zacks, D.N., Zacksenhaus, E., Zaffaroni, N., Zaglia, T., Zakeri, Z., Zecchini, V., Zeng, J., Zeng, M., Zeng, Q., Zervos, A.S., Zhang, D.D., Zhang, F., Zhang, G., Zhang, G.-C., Zhang, H., Zhang, H., Zhang, H., Zhang, J., Zhang, J., Zhang, J., Zhang, J.-P., Zhang, L., Zhang, L., Zhang, L., Zhang, M.-Y., Zhang, X., Zhang, X.D., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhang, Y., Zhao, M., Zhao, W.-L., Zhao, X., Zhao, Y.G., Zhao, Y., Zhao, Y., Zhao, Y.-X., Zhao, Z., Zhao, Z.J., Zheng, D., Zheng, X.-L., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, G.-Z., Zhou, G., Zhou, H., Zhou, S.-F., Zhou, X.-J., Zhu, H., Zhu, H., Zhu, W.-G., Zhu, W., nd Zhu, X.-F., Zhu, Y., Zhuang, S.-M., Zhuang, X., Ziparo, E., Zois, C.E., Zoladek, T., Zong, W.-X., Zorzano, A., Zughaier, S.M.

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    DOI： 10.1016/j.virol.2015.06.006

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  • Untangling autophagy measurements all fluxed up

    Gottlieb, R.A., Andres, A.M., Sin, J., Taylor, D.P.J.

    Circulation Research   116 ( 3 )   2015

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    DOI： 10.1161/CIRCRESAHA.116.303787

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  • Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy

    Delbridge, L.M.D., Mellor, K.M., Taylor, D.J.R., Gottlieb, R.A.

    American Journal of Physiology Heart and Circulatory Physiology   308 ( 10 )   2015

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    DOI： 10.1152/ajpheart.00002.2015

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  • Mitochondrial quality control: Easy come, easy go

    Stotland, A., Gottlieb, R.A.

    Biochimica Et Biophysica Acta Molecular Cell Research   1853 ( 10 )   2015

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    DOI： 10.1016/j.bbamcr.2014.12.041

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  • Erratum: The association of statin use after cancer diagnosis with survival in pancreatic cancer patients: A Seer-Medicare analysis (PLoS ONE (2015) 10:4 (e0121783) DOI:doi:10.1371/journal.pone.0121783)

    Jeon, C.Y., Pandol, S.J., Wu, B., Cook-Wiens, G., Gottlieb, R.A., Merz, C.N.B., Goodman, M.T.

    Plos One   10 ( 5 )   2015

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    DOI： 10.1371/journal.pone.0128730

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  • Measuring Cardiac Autophagic Flux In Vitro and In Vivo

    Gurney, M.A., Huang, C., Ramil, J.M., Ravindran, N., Andres, A.M., Sin, J., Linton, P.-J., Gottlieb, R.A.

    Methods in Molecular Biology   1219   2015

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    DOI： 10.1007/978-1-4939-1661-0_14

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  • ここが知りたい循環器診療―パールとピットフォール 一般外来でよくみる循環器疾患 心不全 心不全患者への生活指導・リハビリテーション

    塚田(哲翁)弥生

    Medicina   51 ( 9 )   1728 - 1731   2014.9

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    Authorship：Lead author   Language：Japanese  

    J-GLOBAL

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  • 家庭用心電図委員会の報告 女性における種々の心臓症状評価に有用な症例の予備的報告(Report from Home Electrocardiography Committee: Preliminary Report of the Cases Usefull for the Evaluation of Various Cardiac Symptoms in Women)

    Yashima Masaaki, Tsukada Yayoi, Sato Kayoko, Fukushima Seiji, Amano Keiko, Katoh Takao

    心電図   34 ( Suppl.3 )   433 - 433   2014.6

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  • 定期的なベータ遮断薬療法は急性心不全症候群の急性肺水腫に対する気管内挿管を減少させる(Regular Beta-blocker Therapy Reduces Endotracheal Intubation for Acute Pulmonary Edema in Acute Heart Failure Syndromes) Reviewed

    Murai Koji, Asai Kuniya, Oka Eiichiro, Fukuizumi Isamu, Furuse Erito, Yoshinaga Aya, Kubota Yoshiaki, Yoshikawa Masatomo, Tetsuou-Tsukada Yayoi, Sato Naoki, Shimizu Wataru

    Circulation Journal   78 ( Suppl.I )   374 - 375   2014.3

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  • 急性心不全症候群による入院前の定期的β遮断薬療法の効果(The Effects of Regular Beta Blocker Therapy before Admission for Acute Heart Failure Syndromes) Reviewed

    Murai Koji, Asai Kuniya, Oka Eiichiro, Fukuizumi Isamu, Furuse Erito, Yoshinaga Aya, Kubota Yoshiaki, Yoshikawa Masatomo, Tetsuou-Tsukada Yayoi, Sato Naoki, Shimizu Wataru

    Circulation Journal   78 ( Suppl.I )   175 - 175   2014.3

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  • Reduction of infarct size by the therapeutic protein TAT-Ndi1 in vivo

    Mentzer, R.M., Wider, J., Perry, C.N., Gottlieb, R.A.

    Journal of Cardiovascular Pharmacology and Therapeutics   19 ( 3 )   2014

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    DOI： 10.1177/1074248413515750

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  • Measurement of mitochondrial turnover and life cycle using mitotimer

    Trudeau, K.M., Gottlieb, R.A., Shirihai, O.S.

    Methods in Enzymology   547 ( C )   2014

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/B978-0-12-801415-8.00002-3

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  • Mitophagy is required for acute cardioprotection by simvastatin

    Andres, A.M., Hernandez, G., Lee, P., Huang, C., Ratliff, E.P., Sin, J., Thornton, C.A., Damasco, M.V., Gottlieb, R.A.

    Antioxidants and Redox Signaling   21 ( 14 )   2014

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    DOI： 10.1089/ars.2013.5416

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  • The personal human oral microbiome obscures the effects of treatment on periodontal disease

    Schwarzberg, K., Le, R., Bharti, B., Lindsay, S., Casaburi, G., Salvatore, F., Saber, M.H., Alonaizan, F., Slots, J., Gottlieb, R.A., Caporaso, J.G., Kelley, S.T.

    Plos One   9 ( 1 )   2014

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    DOI： 10.1371/journal.pone.0086708

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  • Cell-permeable protein therapy for complex I dysfunction

    Pepe, S., Mentzer, R.M., Gottlieb, R.A.

    Journal of Bioenergetics and Biomembranes   46 ( 4 )   2014

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10863-014-9559-7

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  • Autophagy and the human heart

    Ito, B.R., Gottlieb, R.A., Mentzer Jr., R.

    Journal of Thoracic and Cardiovascular Surgery   148 ( 1 )   2014

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    DOI： 10.1016/j.jtcvs.2014.03.009

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  • Coxsackievirus B Exits the Host Cell in Shed Microvesicles Displaying Autophagosomal Markers

    Robinson, S.M., Tsueng, G., Sin, J., Mangale, V., Rahawi, S., McIntyre, L.L., Williams, W., Kha, N., Cruz, C., Hancock, B.M., Nguyen, D.P., Sayen, M.R., Hilton, B.J., Doran, K.S., Segall, A.M., Wolkowicz, R., Cornell, C.T., Whitton, J.L., Gottlieb, R.A., Feuer, R.

    Plos Pathogens   10 ( 4 )   2014

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    DOI： 10.1371/journal.ppat.1004045

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  • Foreword

    Gottlieb, R.A.

    Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging   4   2014

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    Publishing type：Research paper (scientific journal)   Publisher：Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging  

    DOI： 10.1016/B978-0-12-405528-5.00023-7

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  • The role of autophagy during group B streptococcus infection of blood-brain barrier endothelium

    Cutting, A.S., Rosario, Y.D., Mu, R., Rodriguez, A., Till, A., Subramani, S., Gottlieb, R.A., Doran, K.S.

    Journal of Biological Chemistry   289 ( 52 )   2014

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    DOI： 10.1074/jbc.M114.588657

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  • The Impact of Juvenile Coxsackievirus Infection on Cardiac Progenitor Cells and Postnatal Heart Development

    Sin, J., Puccini, J.M., Huang, C., Konstandin, M.H., Gilbert, P.E., Sussman, M.A., Gottlieb, R.A., Feuer, R.

    Plos Pathogens   10 ( 7 )   2014

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    DOI： 10.1371/journal.ppat.1004249

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  • ホルター心電図運動療法支援システムの開発による糖尿病症例の心疾患進展防止効果

    塚田(哲翁)弥生

    医科学応用研究財団研究報告(CD-ROM)   30   109 - 112   2013

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    Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (other academic)  

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  • Assessing autophagy

    Gottlieb, R.A.

    Manual of Research Techniques in Cardiovascular Medicine   2013

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    DOI： 10.1002/9781118495148.ch43

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  • Activation of the homeostatic intracellular repair response during cardiac surgery

    Jahania, S.M., Sengstock, D., Vaitkevicius, P., Andres, A., Ito, B.R., Gottlieb, R.A., Mentzer Jr., R.

    Journal of the American College of Surgeons   216 ( 4 )   2013

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    DOI： 10.1016/j.jamcollsurg.2012.12.034

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  • Autophagy in Health and Disease

    Gottlieb, R.A.

    Autophagy in Health and Disease   2013

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    DOI： 10.1016/C2010-0-66523-0

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  • Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

    Riehle, C., Wende, A.R., Sena, S., Pires, K.M., Pereira, R.O., Zhu, Y., Bugger, H., Frank, D., Bevins, J., Chen, D., Perry, C.N., Dong, X.C., Valdez, S., Rech, M., Sheng, X., Weimer, B.C., Gottlieb, R.A., White, M.F., Abel, E.D.

    Journal of Clinical Investigation   123 ( 12 )   2013

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    DOI： 10.1172/JCI71171

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  • Overview. Selective Removal of Aggregates and Organelles.

    Gottlieb, R.A.

    Autophagy in Health and Disease   2013

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    DOI： 10.1016/B978-0-12-385101-7.00001-2

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  • Measuring Autophagy in Vivo

    Gottlieb, R.A.

    Autophagy in Health and Disease   2013

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    DOI： 10.1016/B978-0-12-385101-7.00011-5

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  • Polyamine depletion inhibits the autophagic response modulating Trypanosoma cruzi infectivity

    Vanrell, M.C., Cueto, J.A., Barclay, J.J., Carrillo, C., Colombo, M.I., Gottlieb, R.A., Romano, P.S.

    Autophagy   9 ( 7 )   2013

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    DOI： 10.4161/auto.24709

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  • Tragic heart, magic art

    Gottlieb, R.

    Heart Failure Reviews   18 ( 5 )   555 - 555   2013

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10741-012-9366-3

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  • MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age

    Ferree, A.W., Trudeau, K., Zik, E., Benador, I.Y., Twig, G., Gottlieb, R.A., Shirihai, O.S.

    Autophagy   9 ( 11 )   2013

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.4161/auto.26503

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  • MitoTimer: A novel tool for monitoring mitochondrial turnover

    Hernandez, G., Thornton, C., Stotland, A., Lui, D., Sin, J., Ramil, J., Magee, N., Andres, A., Quarato, G., Carreira, R.S., Sayen, M.R., Wolkowicz, R., Gottlieb, R.A.

    Autophagy   9 ( 11 )   2013

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    DOI： 10.4161/auto.26501

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  • 過去24年間における緊急大動脈疾患の年次推移 患者絶対数の増加、女性比率の上昇、生存率の向上

    野間 さつき, 圷 宏一, 塚田 弥生, 山本 剛, 水野 杏一, 田中 啓治

    日本心臓病学会誌   7 ( Suppl.I )   366 - 366   2012.8

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  • Autophagy, myocardial protection, and the metabolic syndrome

    Giricz, Z., Mentzer, R.M., Gottlieb, R.A.

    Journal of Cardiovascular Pharmacology   60 ( 2 )   2012

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    DOI： 10.1097/FJC.0b013e318256ce10

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  • Indigestible mitochondria cause heartburn

    Gottlieb, R.A., Linton, P.-J.

    Cell Research   22 ( 11 )   2012

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    DOI： 10.1038/cr.2012.96

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  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D.J., Abdalla, F.C., Abeliovich, H., Abraham, R.T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J.A., Ahn, H.J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H.M., Al-Zeer, M.A., Albert, M.L., Albin, R.L., Alegre-Abarrategui, J., Aleo, M.F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A.O., Andrieu-Abadie, N., Anantharam, V., Ann, D.K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J.P., Asanuma, K., Asare, N.Y., Ashida, H., Askanas, V., Askew, D.S., Auberger, P., Baba, M., Backues, S.K., Baehrecke, E.H., Bahr, B.A., Bai, X.-Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B.A., Bampton, E.T., B{\'a}nhegyi, G., Bartholomew, C.R., Bassham, D.C., Bast, R.C., Batoko, H., Bay, B.-H., Beau, I., B{\'e}chet, D.M., Begley, T.J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L.J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J.S., Boise, L.H., Bonaldo, P., Boone, D.L., Bornhauser, B.C., Bortoluci, K.R., Bossis, I., Bost, F., Bourquin, J.-P., Boya, P., Boyer-Guittaut, M., Bozhkov, P.V., Brady, N.R., Brancolini, C., Brech, A., Brenman, J.E., Brennand, A., Bresnick, E.H., Brest, P., Bridges, D., Bristol, M.L., Brookes, P.S., Brown, E.J., Brumell, J.H., Brunetti-Pierri, N., Brunk, U.T., Bulman, D.E., Bultman, S.J., Bultynck, G., Burbulla, L.F., Bursch, W., Butchar, J.P., Buzgariu, W., Bydlowski, S.P., Cadwell, K., Cahov{\'a}, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A.B., Carding, S.R., Cardoso, S.M., Carew, J.S., Carlin, C.R., Carmignac, V., Carneiro, L.A., Carra, S., Caruso, R.A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H.-J., Chai, C.-Y., Chan, D.C., Chan, E.Y., Chang, R.C.-C., Che, C.-M., Chen, C.-C., Chen, G.-C., Chen, G.-Q., Chen, M., Chen, Q., Chen, S.S.-L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y.-G., Chen, Y., Chen, Y., Chen, Y.-J., Chen, Z., Cheng, A., Cheng, C.H., Cheng, Y., Cheong, H., Cheong, J.-H., Cherry, S., Chess-Williams, R., Cheung, Z.H., Chevet, E., Chiang, H.-L., Chiarelli, R., Chiba, T., Chin, L.-S., Chiou, S.-H., Chisari, F.V., Cho, C.H., Cho, D.-H., Choi, A.M., Choi, D., Choi, K.S., Choi, M.E., Chouaib, S., Choubey, D., Choubey, V., Chu, C.T., Chuang, T.-H., Chueh, S.-H., Chun, T., Chwae, Y.-J., Chye, M.-L., Ciarcia, R., Ciriolo, M.R., Clague, M.J., Clark, R.S., Clarke, P.G., Clarke, R., Codogno, P., Coller, H.A., Colombo, M.I., Comincini, S., Condello, M., Condorelli, F., Cookson, M.R., Coombs, G.H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F.P., Cregg, J.M., Crespo, J.L., Cronj{\'e}, M.J., Cuervo, A.M., Cullen, J.J., Czaja, M.J., D{'}Amelio, M., Darfeuille-Michaud, A., Davids, L.M., Davies, F.E., De Felici, M., de Groot, J.F., de Haan, C.A., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L.M., Demarchi, F., Deng, Y.Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S.D., Devenish, R.J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., D{\'i}az-Araya, G., D{\'i}az-Laviada, I., Diaz-Meco, M.T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S.P., Ding, W.-X., Distelhorst, C.W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F.C., Dosenko, V., Dowling, J.J., Doxsey, S., Dreux, M., Drew, M.E., Duan, Q., Duchosal, M.A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C.L., Edinger, A.L., Egea, G., Eichinger, L., Eissa, N.T., Ekmekcioglu, S., El-Deiry, W.S., Elazar, Z., Elgendy, M., Ellerby, L.M., Eng, K.E., Engelbrecht, A.-M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E.-L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q.-W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farr{\'e}, J.-C., Faure, M., Fechheimer, M., Feng, C.G., Feng, J., Feng, Q., Feng, Y., F{\'e}s{\"u}s, L., Feuer, R., Figueiredo-Pereira, M.E., Fimia, G.M., Fingar, D.C., Finkbeiner, S., Finkel, T., Finley, K.D., Fiorito, F., Fisher, E.A., Fisher, P.B., Flajolet, M., Florez-McClure, M.L., Florio, S., Fon, E.A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D.H., Fox, H.S., Franco, R., Frankel, L.B., Fransen, M., Fuentes, J.M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R.H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I.G., Gao, F.-B., Gao, G.F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A.L., Gatti, E., Gautel, M., Gawriluk, T.R., Gegg, M.E., Geng, J., Germain, M., Gestwicki, J.E., Gewirtz, D.A., Ghavami, S., Ghosh, P., Giammarioli, A.M., Giatromanolaki, A.N., Gibson, S.B., Gilkerson, R.W., Ginger, M.L., Ginsberg, H.N., Golab, J., Goligorsky, M.S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C.D., Gonzalez, R., Gonz{\'a}lez-Est{\'e}vez, C., Gonz{\'a}lez-Polo, R.A., Gonzalez-Rey, E., Gorbunov, N.V., Gorski, S., Goruppi, S., Gottlieb, R.A., Gozuacik, D., Granato, G.E., Grant, G.D., Green, K.N., Gregorc, A., Gros, F., Grose, C., Grunt, T.W., Gual, P., Guan, J.-L., Guan, K.-L., Guichard, S.M., Gukovskaya, A.S., Gukovsky, I., Gunst, J., Gustafsson, A.B., Halayko, A.J., Hale, A.N., Halonen, S.K., Hamasaki, M., Han, F., Han, T., Hancock, M.K., Hansen, M., Harada, H., Harada, M., Hardt, S.E., Harper, J.W., Harris, A.L., Harris, J., Harris, S.D., Hashimoto, M., Haspel, J.A., Hayashi, S., Hazelhurst, L.A., He, C., He, Y.-W., H{\'e}bert, M.-J., Heidenreich, K.A., Helfrich, M.H., Helgason, G.V., Henske, E.P., Herman, B., Herman, P.K., Hetz, C., Hilfiker, S., Hill, J.A., Hocking, L.J., Hofman, P., Hofmann, T.G., H{\"o}hfeld, J., Holyoake, T.L., Hong, M.-H., Hood, D.A., Hotamisligil, G.S., Houwerzijl, E.J., H?yer-Hansen, M., Hu, B., d Hu, C.-A.A., Hu, H.-M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W.-P., Huber, T.B., Huh, W.-K., Hung, T.-H., Hupp, T.R., Hur, G.M., Hurley, J.B., Hussain, S.N., Hussey, P.J., Hwang, J.J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J.L., Ip, N.Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P.M., J, a, a}ttel{\"a}, M., Jackson, G.R., Jackson, W.T., Janji, B., Jendrach, M., Jeon, J.-H., Jeung, E.-B., Jiang, H., Jiang, H., Jiang, J., Jiang, M., Jiang, Q., Jiang, X., Jim{\'e}nez, A., Jin, M., Jin, S., Joe, C.O., Johansen, T., Johnson, D.E., Johnson, G.V., Jones, N.L., Joseph, B., Joseph, S.K., Joubert, A.M., Juh{\'a}sz, G., Juillerat-Jeanneret, L., Jung, C.H., Jung, Y.-K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V.O., Kampinga, H.H., Kanamori, H., Kang, C., Kang, K.B., Kang, K.I., Kang, R., Kang, Y.-A., Kanki, T., Kanneganti, T.-D., Kanno, H., Kanthasamy, A.G., Kanthasamy, A., Karantza, V., Kaushal, G.P., Kaushik, S., Kawazoe, Y., Ke, P.-Y., Kehrl, J.H., Kelekar, A., Kerkhoff, C., Kessel, D.H., Khalil, H., Kiel, J.A., Kiger, A.A., Kihara, A., Kim, D.R., Kim, D.-H., Kim, D.-H., Kim, E.-K., Kim, H.-R., Kim, J.-S., Kim, J.H., Kim, J.C., Kim, J.K., Kim, P.K., Kim, S.W., Kim, Y.-S., Kim, Y., Kimchi, A., Kimmelman, A.C., King, J.S., Kinsella, T.J., Kirkin, V., Kirshenbaum, L.A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W.T., Klucken, J., Knecht, E., Ko, B.C., Koch, J.C., Koga, H., Koh, J.-Y., Koh, Y.H., Koike, M., Komatsu, M., Kominami, E., Kong, H.J., Kong, W.-J., Korolchuk, V.I., Kotake, Y., Koukourakis, M.I., Kouri Flores, J.B., Kov{\'a}cs, A.L., Kraft, C., Krainc, D., Kr{\"a}mer, H., Kretz-Remy, C., Krichevsky, A.M., Kroemer, G., Kr{\"u}ger, R., Krut, O., Ktistakis, N.T., Kuan, C.-Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H.-J., Kurz, T., Kwon, H.J., La Spada, A.R., Lafont, F., Lamark, T., Landry, J., Lane, J.D., Lapaquette, P., Laporte, J.F., L{\'a}szl{\'o}, L., Lavandero, S., Lavoie, J.N., Layfield, R., Lazo, P.A., Le, W., Le Cam, L., Ledbetter, D.J., Lee, A.J., Lee, B.-W., Lee, G.M., Lee, J., Lee, J.-H., Lee, M., Lee, M.-S., Lee, S.H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H.-Y., Lei, Q.-Y., Leib, D.A., Leiro, J., Lemasters, J.J., Lemoine, A., Lesniak, M.S., Lev, D., Levenson, V.V., Levine, B., Levy, E., Li, F., Li, J.-L., Li, L., Li, S., Li, W., Li, X.-J., Li, Y., Li, Y.-P., Liang, C., Liang, Q., Liao, Y.-F., Liberski, P.P., Lieberman, A., Lim, H.J., Lim, K.-L., Lim, K., Lin, C.-F., Lin, F.-C., Lin, J., Lin, J.D., Lin, K., Lin, W.-W., Lin, W.-C., Lin, Y.-L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M.P., Liton, P.B., Liu, B., Liu, C.-F., Liu, K., Liu, L., Liu, Q.A., Liu, W., Liu, Y.-C., Liu, Y., Lockshin, R.A., Lok, C.-N., Lonial, S., Loos, B., Lopez-Berestein, G., L{\'o}pez-Ot{\'i}n, C., Lossi, L., Lotze, M.T., L?w, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N.W., Lund, A.H., Lynch-Day, M.A., Ma, Y., Macian, F., MacKeigan, J.P., Macleod, K.F., Madeo, F., Maiuri, L., Maiuri, M.C., Malagoli, D., Malicdan, M.C., Malorni, W., Man, N., Mandelkow, E.-M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y.L., Marchbank, K., Marchetti, P., Marciniak, S.J., Marcondes, M., Mardi, M., Marfe, G., Mari{\~n}o, G., Markaki, M., Marten, M.R., Martin, S.J., Martin, Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N.M., McConkey, D.J., McConnell, M.J., McDermott, C., McDonald, C., McInerney, G.M., McKenna, S.L., McLaughlin, B., McLean, P.J., McMaster, C.R., McQuibban, G.A., Meijer, A.J., Meisler, M.H., Mel{\'e}ndez, A., Melia, T.J., Melino, G., Mena, M.A., Menendez, J.A., Menna-Barreto, R.F., Menon, M.B., Menzies, F.M., Mercer, C.A., Merighi, A., Merry, D.E., Meschini, S., Meyer, C.G., Meyer, T.F., Miao, C.-Y., Miao, J.-Y., Michels, P.A., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C.K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M.M., Monteiro, M.J., Moore, M.N., Mora, R., Moreau, K., Moreira, P.I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J.C., Motyl, T., Moussa, C.E.-H., M{\"u}ller, S., Muller, S., M{\"u}nger, K., M{\"u}nz, C., Murphy, L.O., Murphy, M.E., Musar{\`o}, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N.I., Narendra, D.P., Narita, M., Navarro, M., Nawrocki, S.T., Nazarko, T.Y., Nemchenko, A., Netea, M.G., Neufeld, T.P., Ney, P.A., Nezis, I.P., Nguyen, H.P., Nie, D., Nishino, I., Nislow, C., Nixon, R.A., Noda, T., Noegel, A.A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., N{\"u}rnberger, T., Nyfeler, B., Obara, K., Oberley, T.D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N.L., Oliver, F.J., Olsen, L.J., Olsson, S., Opota, O., Osborne, T.F., Ostrander, G.K., Otsu, K., Ou, J.J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G.E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U.B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O.K., Parys, J.B., Parzych, K.R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J.M., Peng, J., Perlmutter, D.H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G.J., Petersen, M., Petrovski, G., Phang, J.M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L.C., P{\"o}ggeler, S., Poirot, M., Poletti, A., Po{\"u}s, C., Pozuelo-Rubio, M., Pr?torius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S.-B., Qin, L., Qin, Z.-H., Quaggin, S.E., Raben, N., Rabinowich, H., Rabkin, S.W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V.A., Rathmell, J.C., Ravikumar, B., Ray, S.K., Reed, B.H., Reed, J.C., Reggiori, F., R{\'e}gnier-Vigouroux, A., Reichert, A.S., Reiners, J.J., Reiter, R.J., Ren, J., Revuelta, J.L., Rhodes, C.J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M.C., Rocchi, S., Rodemann, H.P., Rodr{\'i}guez de, C{\'o}rdoba, S., Rohrer, B., Roninson, I.B., Rosen, K., Rost-Roszkowska, M.M., Rouis, M., Rouschop, K.M., Rovetta, F., Rubin, B.P., Rubinsztein, D.C., Ruckdeschel, K., Rucker, E.B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T.E., Ryan, K.M., Ryter, S.W., Sabatini, D.M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G.H., Salomoni, P., Salvaterra, P.M., Salvesen, G., Salvioli, R., Sanchez, A.M., S{\'a}nchez-Alc{\'a}zar, J.A., S{\'a}nchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A.H., Scharl, M., Sch{\"a}tzl, H.M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M.E., Schneider-Stock, R., Schoenlein, P.V., Schorderet, D.F., Sch{\"u}ller, C., Schwartz, G.K., Scorrano, L., Sealy, L., Seglen, P.O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J.B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J.J., Shanmugam, M., Shapiro, I.M., Shaulian, E., Shaw, R.J., Shelhamer, J.H., Shen, H.-M., Shen, W.-C., Sheng, Z.-H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J.-J., Shih, C.-M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O.S., Shore, G.C., Sibirny, A.A., Sidhu, S.B., Sikorska, B., Silva-Zacarin, E.C., Simmons, A., Simon, A.K., Simon, H.-U., Simone, C., Simonsen, A., Sinclair, D.A., Singh, R., Sinha, D., Sinicrope, F.A., Sirko, A., Siu, P.M., Sivridis, E., Skop, V., Skulachev, V.P., Slack, R.S., Smaili, S.S., Smith, D.R., Soengas, M.S., Soldati, T., Song, X., Sood, A.K., Soong, T.W., Sotgia, F., Spector, S.A., Spies, C.D., Springer, W., Srinivasula, S.M., Stefanis, L., Steffan, J.S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S.T., Sternberg, C., Stork, B., Str?lfors, P., Subauste, C.S., Sui, X., Sulzer, D., Sun, J., Sun, S.-Y., Sun, Z.-J., Sung, J.J., Suzuki, K., Suzuki, T., Swanson, M.S., Swanton, C., Sweeney, S.T., Sy, L.-K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Tak{\'a}cs-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N.J., Tan, K.S., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B.A., Tavernarakis, N., Taylor, G.S., Taylor, G.A., Taylor, J.P., Terada, L.S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C.B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A.M., Tomino, Y., T{\"o}nges, L., Tooze, S.A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L.H., Tsai, T.-F., Tschan, M.P., Tsubata, T., Tsung, A., Turk, B., Turner, L.S., Tyagi, S.C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V.K., Vaccaro, M.I., Valente, E.M., Van den Berghe, G., van der Klei, I.J., van Doorn, W., van Dyk, L.F., van Egmond, M., van Grunsven, L.A., Vandenabeele, P., Vandenberghe, W.P., Vanhorebeek, I., Vaquero, E.C., Velasco, G., Vellai, T., Vicencio, J.M., Vierstra, R.D., Vila, M., Vindis, C., Viola, G., Viscomi, M.T., Voitsekhovskaja, O.V., von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C.L., Walsh, C.M., Walter, J., Wan, X.-B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H.-G., Wang, H.-D., Wang, J., Wang, K., Wang, M., Wang, R.C., Wang, X., Wang, X., Wang, Y.-J., Wang, Y., Wang, Z., Wang, Z.C., Wang, Z., Wansink, D.G., Ward, D.M., Watada, H., Waters, S.L., Webster, P., Wei, L., Weihl, C.C., Weiss, W.A., Welford, S.M., Wen, L.-P., Whitehouse, C.A., Whitton, J.L., Whitworth, A.J., Wileman, T., Wiley, J.W., Wilkinson, S., Willbold, D., Williams, R.L., Williamson, P.R., Wouters, B.G., Wu, C., d Wu, D.-C., Wu, W.K., Wyttenbach, A., Xavier, R.J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D.-S., Yang, E., Yang, J.-M., Yang, S.Y., Yang, W., Yang, W.Y., Yang, Z., Yao, M.-C., Yao, T.-P., Yeganeh, B., Yen, W.-L., Yin, J., Yin, X.-M., Yoo, O.-J., Yoon, G., Yoon, S.-Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H.J., Youle, R.J., Younes, A., Yu, L., Yu, L., Yu, S.-W., Yu, W.H., Yuan, Z.-M., Yue, Z., Yun, C.-H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., Zacks, D., Zacksenhaus, E., Zaffaroni, N., Zakeri, Z., Zeh, H.J., Zeitlin, S.O., Zhang, H., Zhang, H.-L., Zhang, J., Zhang, J.-P., Zhang, 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    Autophagy   8 ( 4 )   2012

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    American Journal of Physiology Cell Physiology   299 ( 2 )   2010

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    Autophagy   6 ( 4 )   2010

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    Circulation   122 ( 11 SUPPL. 1 )   2010

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    American Journal of Cardiology   106 ( 12 )   1826 - 1826   2010

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  • Pim-1 kinase protects mitochondrial integrity in cardiomyocytes

    Borillo, G.A., Mason, M., Quijada, P., V{\"o}lkers, M., Cottage, C., McGregor, M., Din, S., Fischer, K., Gude, N., Avitabile, D., Barlow, S., Alvarez, R., Truffa, S., Whittaker, R., Glassy, M.S., Gustafsson, A.B., Miyamoto, S., Glembotski, C.C., Gottlieb, R.A., Brown, J.H., Sussman, M.A.

    Circulation Research   106 ( 7 )   2010

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    DOI： 10.1161/CIRCRESAHA.109.212035

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  • Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism

    Quinsay, M.N., Lee, Y., Rikka, S., Sayen, M.R., Molkentin, J.D., Gottlieb, R.A., Gustafsson, ?

    Journal of Molecular and Cellular Cardiology   48 ( 6 )   2010

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    DOI： 10.1016/j.yjmcc.2009.12.004

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  • Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice

    Huang, C., Zhang, X., Ramil, J.M., Rikka, S., Kim, L., Lee, Y., Gude, N.A., Thistlethwaite, P.A., Sussman, M.A., Gottlieb, R.A., Gustafsson, ?

    Circulation   121 ( 5 )   2010

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    DOI： 10.1161/CIRCULATIONAHA.109.902221

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  • 女性循環器勤務医の就労継続のためには何が必要か? : 循環器医の仕事と生活における性差に関する調査結果より(5.女性循環器医の現状と明日への期待,<特集II>第72回日本循環器学会学術集会) Reviewed

    塚田(哲翁) 弥生, 水野 杏一

    循環器専門医 : 日本循環器学会専門医誌   17 ( 1 )   68 - 74   2009.3

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    Authorship：Lead author   Language：Japanese   Publisher：社団法人日本循環器学会  

    CiNii Books

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  • Modulation of cardiac function by lipid metabolites

    Gottlieb, R.A.

    Journal of Cardiovascular Pharmacology   53 ( 3 )   2009

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    DOI： 10.1097/FJC.0b013e31819ea5e9

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  • Cardioprotection requires taking out the trash

    Gottlieb, R.A., Finley, K.D., Mentzer Jr., R.

    Basic Research in Cardiology   104 ( 2 )   2009

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    DOI： 10.1007/s00395-009-0011-9

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  • Chapter 16 Novel Methods for Measuring Cardiac Autophagy In Vivo

    Perry, C.N., Kyoi, S., Hariharan, N., Takagi, H., Sadoshima, J., Gottlieb, R.A.

    Methods in Enzymology   453 ( C )   2009

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    DOI： 10.1016/S0076-6879(08)04016-0

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  • Kinetics of the translocation and phosphorylation of αB-crystallin in mouse heart mitochondria during ex vivo ischemia

    Whittaker, R., Glassy, M.S., Gude, N., Sussman, M.A., Gottlieb, R.A., Glembotski, C.

    American Journal of Physiology Heart and Circulatory Physiology   296 ( 5 )   2009

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    DOI： 10.1152/ajpheart.01227.2008

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  • Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA

    Yitzhaki, S., Huang, C., Liu, W., Lee, Y., Gustafsson, ?.B., Mentzer Jr., R.M., Gottlieb, R.A.

    Basic Research in Cardiology   104 ( 2 )   2009

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    DOI： 10.1007/s00395-009-0006-6

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  • Autophagy during cardiac stress: Joys and frustrations of autophagy

    Gottlieb, R.A., Mentzer, R.M.

    Annual Review of Physiology   72   2009

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    DOI： 10.1146/annurev-physiol-021909-135757

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  • Autophagy in ischemic heart disease

    Gustafsson, ?, B, Gottlieb, R.A.

    Circulation Research   104 ( 2 )   2009

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1161/CIRCRESAHA.108.187427

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  • LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection

    Yuan, H., Perry, C.N., Huang, C., Iwai-Kanai, E., Carreira, R.S., Glembotski, C.C., Gottlieb, R.A.

    American Journal of Physiology Heart and Circulatory Physiology   296 ( 2 )   2009

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpheart.01051.2008

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  • Sulfaphenazole Mediates Cardioprotection Through Preconditioning and Autophagy

    Chengqun Huang, Yayoi Tetsuo Tsukada, Cynthia N. Perry-Garza, Robert M. Mentzer, Roberta A. Gottlieb

    CIRCULATION RESEARCH   103 ( 5 )   E52 - E52   2008.8

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    Web of Science

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  • Eat your heart out: Role of autophagy in myocardial ischemia/reperfusion

    Gustafsson, ?, B, Gottlieb, R.A.

    Autophagy   4 ( 4 )   2008

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.4161/auto.5655

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  • A method to measure cardiac autophagic flux in vivo

    Iwai-Kanai, E., Yuan, H., Huang, C., Sayen, M.R., Perry-Garza, C.N., Kim, L., Gottlieb, R.A.

    Autophagy   4 ( 3 )   2008

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.4161/auto.5603

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  • Heart mitochondria: Gates of life and death

    Gustafsson, ?, B, Gottlieb, R.A.

    Cardiovascular Research   77 ( 2 )   2008

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    DOI： 10.1093/cvr/cvm005

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  • Recycle or die: The role of autophagy in cardioprotection

    Gustafsson, ?, B, Gottlieb, R.A.

    Journal of Molecular and Cellular Cardiology   44 ( 4 )   2008

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.yjmcc.2008.01.010

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  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Klionsky, D.J., Abeliovich, H., Agostinis, P., Agrawal, D.K., Aliev, G., Askew, D.S., Baba, M., Baehrecke, E.H., Bahr, B.A., Ballabio, A., Bamber, B.A., Bassham, D.C., Bergamini, E., Bi, X., Biard-Piechaczyk, M., Blum, J.S., Bredesen, D.E., Brodsky, J.L., Brumell, J.H., Brunk, U.T., Bursch, W., Camougrand, N., Cebollero, E., Cecconi, F., Chen, Y., Chin, L.-S., Choi, A., Chu, C.T., Chung, J., Clarke, P.G.H., Clark, R.S.B., Clarke, S.G., Clav{\'e}, C., Cleveland, J.L., Codogno, P., Colombo, M.I., Cotomontes, A., Cregg, J.M., Cuervo, A.M., Debnath, J., Demarchi, F., Dennis, P.B., Dennis, P.A., Deretic, V., Devenish, R.J., Di Sano, F., Dice, J.F., DiFiglia, M., Dinesh-Kumar, S., Distelhorst, C.W., Djavaheri-Mergny, M., Dorsey, F.C., Dr{\"o}ge, W., Dron, M., Dunn Jr., W.A., Duszenko, M., Eissa, N.T., Elazar, Z., Esclatine, A., Eskelinen, E.-L., F{\'e}s{\"u}s, L., Finley, K.D., Fuentes, J.M., Fueyo, J., Fujisaki, K., Galliot, B., Gao, F.-B., Gewirtz, D.A., Gibson, S.B., Gohla, A., Goldberg, A.L., Gonzalez, R., Gonz{\'a}lez-Est{\'e}vez, C., Gorski, S., Gottlieb, R.A., H{\"a}ussinger, D., He, Y.-W., Heidenreich, K., Hill, J.A., H?yer-Hansen, M., Hu, X., Huang, W.-P., Iwasaki, A., J, a, a}ttel{\"a}, M., Jackson, W.T., Jiang, X., Jin, S., Johansen, T., Jung, J., Kadowaki, M., Kang, C., Kelekar, A., Kessel, D.H., d Kiel, J.A.K.W., Hong, P.K., Kimchi, A., Kinsella, T.J., Kiselyov, K., Kitamoto, K., Knecht, E., Komatsu, M., Kominami, E., Kondo, S., Kov{\'a}cs, A.L., Kroemer, G., Kuan, C.-Y., Kumar, R., Kundu, M., Landry, J., Laporte, M., Le, W., Lei, H.-Y., Lenardo, M.J., Levine, B., Lieberman, A., Lim, K.-L., Lin, F.-C., Liou, W., Liu, L.F., Lopez-Berestein, G., L{\'o}pez-Ot{\'i}n, C., Lu, B., Macleod, K.F., Malorni, W., Martinet, W., Matsuoka, K., Mautner, J., Meijer, A.J., Mel{\'e}ndez, A., Michels, P., Miotto, G., Mistiaen, W.P., Mizushima, N., Mograbi, B., Monastyrska, I., Moore, M.N., Moreira, P.I., Moriyasu, Y., Motyl, T., M{\"u}nz, C., Murphy, L.O., Naqvi, N.I., Neufeld, T.P., Nishino, I., Nixon, R.A., Noda, T., N{\"u}rnberg, B., Ogawa, M., Oleinick, N.L., Olsen, L.J., Ozpolat, B., Paglin, S., Palmer, G.E., Papassideri, I., Parkes, M., Perlmutter, D.H., Perry, G., Piacentini, M., Pinkas-Kramarski, R., Prescott, M., Proikascezanne, T., Raben, N., Rami, A., Reggiori, F., Rohrer, B., Rubinsztein, D.C., Ryan, K.M., Sadoshima, J., Sakagami, H., Sakai, Y., Sandri, M., Sasakawa, C., Sass, M., Schneider, C., Seglen, P.O., Seleverstov, O., Settleman, J., Shacka, J.J., Shapiro, I.M., Sibirny, A., Silva-Zacarin, E.C.M., Simon, H.-U., Simone, C., Simonsen, A., Smith, M.A., Spanel-Borowski, K., Srinivas, V., Steeves, M., Stenmark, H., Stromhaug, P.E., Subauste, C.S., Sugimoto, S., Sulzer, D., Suzuki, T., Swanson, M.S., Tabas, I., Takeshita, F., Talbot, N.J., Tall{\'o}czy, Z., Tanaka, K., Tanaka, K., Tanida, I., Taylor, G.S., Taylor, J.P., Terman, A., Tettamanti, G., Thompson, C.B., Thumm, M., Tolkovsky, A.M., Tooze, S.A., Truant, R., Tumanovska, L.V., Uchiyama, Y., Ueno, T., Uzc{\'a}tegui, N.L., Van Der Klei, I., Vaquero, E.C., Vellai, T., Vogel, M.W., Wang, H.-G., Webster, P., Wiley, J.W., Xi, Z., Xiao, G., Yahalom, J., Yang, J.-M., Yap, G., Yin, X.-M., Yoshimori, T., Yu, L., Yue, Z., Yuzaki, M., Zabirnyk, O., Zheng, X., Zhu, X., Deter, R.L.

    Autophagy   4 ( 2 )   2008

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    DOI： 10.4161/auto.5338

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  • Localization of phosphorylated αB-crystallin to heart mitochondria during ischemia-reperfusion

    Jin, J.-K., Whittaker, R., Glassy, M.S., Barlow, S.B., Gottlieb, R.A., Glembotski, C.

    American Journal of Physiology Heart and Circulatory Physiology   294 ( 1 )   2008

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpheart.00881.2007

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  • Chemotherapy and cardiotoxicity

    Broder, H., Gottlieb, R.A., Lepor, N.E.

    Reviews in Cardiovascular Medicine   9 ( 2 )   2008

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  • [Adverse effects of cardiovascular agents]. Reviewed

    Tsukada YT, Kishida H

    Nihon rinsho. Japanese journal of clinical medicine   65 Suppl 8   146 - 151   2007.10

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  • [Home-based management in patients with chronic heart failure].

    Tsukada YT, Katoh YK, Seino Y

    Nihon rinsho. Japanese journal of clinical medicine   65 Suppl 5   323 - 328   2007.5

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (scientific journal)  

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  • Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

    Hamacher-Brady, A., Brady, N.R., Logue, S.E., Sayen, M.R., Jinno, M., Kirshenbaum, L.A., Gottlieb, R.A., Gustafsson, ?

    Cell Death and Differentiation   14 ( 1 )   2007

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/sj.cdd.4401936

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  • CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice

    Benjamin, I.J., Guo, Y., Srinivasan, S., Boudina, S., Taylor, R.P., Rajasekaran, N.S., Gottlieb, R., Wawrousek, E.F., Abel, E.D., Bolli, R.

    American Journal of Physiology Heart and Circulatory Physiology   293 ( 5 )   2007

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    DOI： 10.1152/ajpheart.01363.2006

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  • The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores

    Brady, N.R., Hamacher-Brady, A., Yuan, H., Gottlieb, R.A.

    FEBS Journal   274 ( 12 )   2007

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/j.1742-4658.2007.05849.x

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  • Bcl-2 family members and apoptosis, taken to heart

    Gustafsson, ?, B, Gottlieb, R.A.

    American Journal of Physiology Cell Physiology   292 ( 1 )   2007

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpcell.00229.2006

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  • Having a heart attack? Avoid the "HETE"!

    Granville, D.J., Gottlieb, R.A.

    American Journal of Physiology Heart and Circulatory Physiology   291 ( 2 )   2006

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpheart.00241.2006

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  • A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria

    Brady, N.R., Hamacher-Brady, A., Westerhoff, H.V., Gottlieb, R.A.

    Antioxidants and Redox Signaling   8 ( 9-10 )   2006

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1089/ars.2006.8.1651

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  • Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes

    Hamacher-Brady, A., Brady, N.R., Gottlieb, R.A.

    Journal of Biological Chemistry   281 ( 40 )   2006

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1074/jbc.M603783200

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  • Clinical implications of apoptosis in ischemic myocardium

    Scarabelli, T.M., Knight, R., Stephanou, A., Townsend, P., Chen-Scarabelli, C., Lawrence, K., Gottlieb, R., Latchman, D., Narula, J.

    Current Problems in Cardiology   31 ( 3 )   2006

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    DOI： 10.1016/j.cpcardiol.2005.11.002

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  • Alterations in oxidative phosphorylation complex proteins in the hearts of transgenic mice that overexpress the p38 MAP kinase activator, MAP kinase kinase 6

    Wall, J.A., Wei, J., Ly, M., Belmont, P., Martindale, J.J., Tran, D., Sun, J., Chen, W.J., Yu, W., Oeller, P., Briggs, S., Gustafsson, A.B., Sayen, M.R., Gottlieb, R.A., Glembotski, C.

    American Journal of Physiology Heart and Circulatory Physiology   291 ( 5 )   2006

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    DOI： 10.1152/ajpheart.01311.2005

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  • Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart

    Hamacher-Brady, A., Brady, N.R., Gottlieb, R.A., Gustafsson, ?

    Autophagy   2 ( 4 )   2006

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.4161/auto.2947

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  • The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: Apoptosis meets autophagy

    Hamacher-Brady, A., Brady, N.R., Gottlieb, R.A.

    Cardiovascular Drugs and Therapy   20 ( 6 )   2006

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10557-006-0583-7

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  • Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors

    Brady, N.R., Hamacher-Brady, A., Gottlieb, R.A.

    Biochimica Et Biophysica Acta Bioenergetics   1757 ( 5-6 )   2006

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    DOI： 10.1016/j.bbabio.2006.04.011

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  • Ischemia/reperfusion injury at the intersection with cell death

    Logue, S.E., Gustafsson, ?, B, Samali, A., Gottlieb, R.A.

    Journal of Molecular and Cellular Cardiology   38 ( 1 )   2005

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.yjmcc.2004.11.009

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  • TAT-mediated protein transduction: delivering biologically active proteins to the heart.

    Gustafsson, A.B., Gottlieb, R.A., Granville, D.J.

    Methods in Molecular Medicine   112   2005

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  • Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

    Baines, C.P., Kaiser, R.A., Purcell, N.H., Blair, N.S., Osinska, H., Hambleton, M.A., Brunskill, E.W., Sayen, M.R., Gottlieb, R.A., Dorn II, G.W., Bobbins, J., Molkentin, J.D.

    Nature   434 ( 7033 )   2005

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    DOI： 10.1038/nature03434

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  • ICE-ing the heart

    Gottlieb, R.

    Circulation Research   96 ( 10 )   2005

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1161/01.RES.0000169466.84402.c1

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  • Cytochromes P450 and ischemic heart injury: Potential role for inhibitors in the treatment of myocardial infarction

    Granville, D.J., Gottlieb, R.A.

    Drug Discovery Today Disease Mechanisms   2 ( 1 )   2005

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    DOI： 10.1016/j.ddmec.2005.05.005

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  • Acta Hæmatologica: Introduction

    Gottlieb, R.A.

    Acta Haematologica   111 ( 1-2 )   2004

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    DOI： 10.1159/000074482

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  • Functional and clinical repercussions of myocyte apoptosis in the multifaceted damage by ischemia/reperfusion injury: Old and new concepts after 10 years of contributions

    Scarabelli, T.M., Gottlieb, R.A.

    Cell Death and Differentiation   11   2004

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1038/sj.cdd.4401544

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  • Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation

    Gustafsson, ?, B, Tsai, J.G., Logue, S.E., Crow, M.T., Gottlieb, R.A.

    Journal of Biological Chemistry   279 ( 20 )   2004

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1074/jbc.M400695200

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  • Identification of Targets of Phosphorylation in Heart Mitochondria

    Gottlieb, R.A., He, H.

    Proteomic and Genomic Analysis of Cardiovascular Disease   357   2004

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    Publishing type：Research paper (scientific journal)   Publisher：Methods in Molecular Biology  

    DOI： 10.1002/352760152X.ch16

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  • Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors

    Granville, D.J., Tashakkor, B., Takeuchi, C., Gustafsson, A.B., Huang, C., Sayen, M.R., Wentworth Jr., P., Yeager, M., Gottlieb, R.A.

    Proceedings of the National Academy of Sciences of the United States of America   101 ( 5 )   2004

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1073/pnas.0308185100

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  • Cytochrome P450: Major player in reperfusion injury

    Gottlieb, R.A.

    Archives of Biochemistry and Biophysics   420 ( 2 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.abb.2003.07.004

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  • Mechanisms of Apoptosis in the Heart

    Gustafsson, ?, B, Gottlieb, R.A.

    Journal of Clinical Immunology   23 ( 6 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1023/B:JOCI.0000010421.56035.60

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  • Cytochrome c dissociation and release from mitochondria by truncated Bid and ceramide

    Yuan, H., Williams, S.D., Adachi, S., Oltersdorf, T., Gottlieb, R.A.

    Mitochondrion   2 ( 4 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/S1567-7249(02)00106-X

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  • Debatable contribution of mitochondrial swelling to cell swelling in ischemia

    Gottlieb, R.A.

    Journal of Molecular and Cellular Cardiology   35 ( 7 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/S0022-2828(03)00149-4

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  • Mitochondrial signaling in apoptosis: Mitochondrial daggers to the breaking heart

    Gottlieb, R.A.

    Basic Research in Cardiology   98 ( 4 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00395-003-0404-0

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  • Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

    Ricci, J.-E., Gottlieb, R.A., Green, D.R.

    Journal of Cell Biology   160 ( 1 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1083/jcb.200208089

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  • Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production

    Sayen, M.R., Gustafsson, ?.B., Sussman, M.A., Molkentin, J.D., Gottlieb, R.A.

    American Journal of Physiology Cell Physiology   284 ( 2 53-2 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpcell.00336.2002

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  • Type II secretory phospholipase A2 binds to ischemic flip-flopped cardiomyocytes and subsequently induces cell death

    Nijmeijer, R., Willemsen, M., Meijer, C.J.L.M., Visser, C.A., Verheijen, R.H., Gottlieb, R.A., Hack, C.E., Niessen, H.W., M

    American Journal of Physiology Heart and Circulatory Physiology   285 ( 5 54-5 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1152/ajpheart.00887.2002

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  • The mitochondrial voltage-dependent anion channel (VDAC) as a therapeutic target for initiating cell death

    Granville, D.J., Gottlieb, R.A.

    Current Medicinal Chemistry   10 ( 16 )   2003

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.2174/0929867033457214

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  • Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective

    Williams, S.D., Gottlieb, R.A.

    Biochemical Journal   362 ( 1 )   2002

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1042/bj3620023

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  • Analyzing mitochondrial changes during apoptosis

    Gottlieb, R.A., Granville, D.J.

    Methods   26 ( 4 )   2002

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    DOI： 10.1016/S1046-2023(02)00040-3

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  • Calpain and mitochondria in ischemia/reperfusion injury.

    Chen, M., Won, D.J., Krajewski, S., Gottlieb, R.A.

    Journal of Biological Chemistry   277 ( 32 )   2002

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    DOI： 10.1074/jbc.M204951200

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  • Mitochondria: regulators of cell death and survival.

    Granville, D.J., Gottlieb, R.A.

    Thescientificworldjournal   2   2002

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    DOI： 10.1100/tsw.2002.809

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  • TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective

    Gustafsson, ?.B., Sayen, M.R., Williams, S.D., Crow, M.T., Gottlieb, R.A.

    Circulation   106 ( 6 )   2002

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    DOI： 10.1161/01.CIR.0000023943.50821.F7

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  • Pharmacology of caspase inhibitors in rabbit cardiomyocytes subjected to metabolic inhibition and recovery

    Hai Ling Li, Karwatowska-Prokopczuk, E., Mutomb, M., Wu, J., Karanewsky, D., Valentino, K., Engler, R.L., Gottlieb, R.A.

    Antioxidants and Redox Signaling   3 ( 1 )   2001

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    DOI： 10.1089/152308601750100605

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  • Proliferation, not apoptosis, alters epithelial cell migration in small intestine of CFTR null mice

    Gallagher, A.M., Gottlieb, R.A.

    American Journal of Physiology Gastrointestinal and Liver Physiology   281 ( 3 44-3 )   2001

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    DOI： 10.1152/ajpgi.2001.281.3.g681

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  • Mitochondria and apoptosis

    Gottlieb, R.A.

    Neurosignals   10 ( 3-4 )   2001

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    DOI： 10.1159/000046884

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  • Bid is Cleaved by Calpain to an Active Fragment in Vitro and during Myocardial Ischemia/Reperfusion

    Chen, M., He, H., Zhan, S., Krajewski, S., Reed, J.C., Gottlieb, R.A.

    Journal of Biological Chemistry   276 ( 33 )   2001

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    DOI： 10.1074/jbc.M103701200

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  • Phosphorylation of mitochondrial elongation factor Tu in ischemic myocardium: Basis for chloramphenicol-mediated cardioprotection

    He, H., Chen, M., Scheffler, N.K., Gibson, B.W., Spremulli, L.L., Gottlieb, R.A.

    Circulation Research   89 ( 5 )   2001

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    DOI： 10.1161/hh1701.096038

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  • Differential processing of cytosolic and mitochondrial caspases

    Yuan, H., Mutomba, M., Prinz, I., Gottlieb, R.A.

    Mitochondrion   1 ( 1 )   2001

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    DOI： 10.1016/S1567-7249(01)00002-2

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  • Seeing death in the living

    Gottlieb, R.A., Kitsis, R.N.

    Nature Medicine   7 ( 12 )   2001

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    DOI： 10.1038/nm1201-1277

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  • Programmed cell death

    Gottlieb, R.A.

    Drug News and Perspectives   13 ( 8 )   2000

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  • Role of mitochondria in apoptosis

    Gottlieb, R.A.

    Critical Reviews in Eukaryotic Gene Expression   10 ( 3-4 )   2000

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    DOI： 10.1615/CritRevEukarGeneExpr.v10.i3-4.20

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  • Mitochondria: Execution central

    Gottlieb, R.A.

    FEBS Letters   482 ( 1-2 )   2000

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    DOI： 10.1016/S0014-5793(00)02010-X

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  • Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine

    Mutomba, M.C., Yuan, H., Konyavko, M., Adachi, S., Yokoyama, C.B., Esser, V., McGarry, J.D., Babior, B.M., Gottlieb, R.A.

    FEBS Letters   478 ( 1-2 )   2000

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    DOI： 10.1016/S0014-5793(00)01817-2

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  • Nitrogen cavitation for cell disruption to obtain mitochondria from cultured cells

    Gottlieb, R.A., Adachi, S.

    Methods in Enzymology   322   2000

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    DOI： 10.1016/s0076-6879(00)22022-3

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  • 心嚢液PCR法により診断されたToxoplasma pericarditisの1例 Reviewed

    池田 真人, 小谷 英太郎, 塚田 弥生, 佐野 純子, 小林 義典, 斎藤 寛和, 高山 守正, 里村 克章, 高野 照夫, 岸田 浩

    Japanese Circulation Journal   62 ( Suppl.III )   909 - 909   1999.2

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  • Enhanced DNA fragmentation in the thymus of spontaneously hypertensive rats

    Suzuki, H., Delano, F.A., Jamshidi, N., Katz, D., Mori, M., Kosaki, K., Gottlieb, R.A., Ishii, H., Schmid-Sch{\"o}nbein, G.

    American Journal of Physiology Heart and Circulatory Physiology   276 ( 6 45-6 )   1999

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    DOI： 10.1152/ajpheart.1999.276.6.h2135

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  • Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

    He, H., Li, H.-L., Lin, A., Gottlieb, R.A.

    Cell Death and Differentiation   6 ( 10 )   1999

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    DOI： 10.1038/sj.cdd.4400572

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  • Mitochondria: Ignition chamber for apoptosis

    Gottlieb, R.A.

    Molecular Genetics and Metabolism   68 ( 2 )   1999

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    DOI： 10.1006/mgme.1999.2921

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  • Lack of release of cytochrome c from mitochondria into cytosol early in the course of Fas-mediated apoptosis of jurkat cells

    Adachi, S., Gottlieb, R.A., Babior, B.

    Journal of Biological Chemistry   273 ( 31 )   1998

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    DOI： 10.1074/jbc.273.31.19892

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  • Effect of vacuolar proton ATPase on pH(i), Ca2+, and apoptosis in neonatal cardiomyocytes during metabolic inhibition/recovery

    Karwatowska-Prokopczuk, E., Nordberg, J.A., Li, H.L., Engler, R.L., Gottlieb, R.A.

    Circulation Research   82 ( 11 )   1998

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    DOI： 10.1161/01.RES.82.11.1139

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  • Preoperative evaluation of heart failure patients and anesthetic planning. Disease state of the ischemic heart disease and the preoperative evaluation. Reviewed

    JJSCA   17 ( 10 )   561 - 567   1997

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    DOI： 10.2199/jjsca.17.561

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  • Assessment of left ventricular systolic function derived from ECG-gated myocardial SPECT with 99mTc-tetrofosmin: Automatic determination of LV epi- and endocardial surface Reviewed

    S Kumita, K Cho, S Mizumura, T Kjima, M Ishihara, M Toba, K Inoue, T Kumazaki, J Sano: Y Tada, Y Tetsuou, S Sakai, Y Kusama, K Munakata

    Kakuigaku   34 ( 4 )   237 - 242   1997

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    Non-invasive assessment of ischemic heart disease requires information of both LV function and myocardial perfusion. Recently, ECG-gated myocardial SPECT with technetium-labeled radiopharmaceuticals can provide both of them. Gated myocardial SPECT were performed in thirty-three patients with cardiac disease using a two-headed rotating gamma camera system (ADAC
    VERTEX), 30- 60 minutes after resting injection of 555-740 MBq of 99mTc-Tetrofosmin. Then, the SPECT data were used to determine the LV epi- and endocardial surface, and LV volume for measurement of LVEF was calculated automatically. This entire computational process required only 210 seconds per 16 frame study. Inter-observer agreement of EF values obtained from gated SPECT was excellent (r = 0.996, n = 10, p&lt
    0.01). LVEFs obtained from gated SPECT showed good correlation to those calculated from radionuclide ventriculography (MUGA) (r = 0.91, p&lt
    0.01). In conclusion, this automatic method using gated myocardial SPECT data was considered to be useful for assessment of LV function with reproducibility.

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  • Granulocyte colony-stimulating factor upregulates the vacuolar proton ATPase in human neutrophils

    Niessen, H., Meisenholder, G.W., Li, H.-L., Gluck, S.L., Lee, B.S., Bowman, B., Engler, R.L., Babior, B.M., Gottlieb, R.A.

    Blood   90 ( 11 )   1997

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    DOI： 10.1182/blood.v90.11.4598

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  • Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis

    Adachi, S., Cross, A.R., Babior, B.M., Gottlieb, R.A.

    Journal of Biological Chemistry   272 ( 35 )   1997

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    DOI： 10.1074/jbc.272.35.21878

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  • Regulation of Fas-Mediated Apoptosis

    Gottlieb, R.A., Babior, B.

    Current Topics in Cellular Regulation   35 ( C )   1997

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    DOI： 10.1016/S0070-2137(97)80003-9

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  • [ECG-gated myocardial SPECT with 99mTc-MIBI in patients with right ventricular infarction]. Reviewed

    Kumita S, Mizumura S, Cho K, Kijima T, Kumazaki T, Tetsuou Y, Sakai S, Sano J, Kusama Y, Munakata K

    Kaku igaku. The Japanese journal of nuclear medicine   33 ( 6 )   635 - 639   1996.6

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  • 心拍変動と血圧変動の関係 圧受容体反射による修飾

    福間 長知, 岸田 浩, 哲翁 弥生

    Therapeutic Research   17 ( 6 )   1928 - 1932   1996.6

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    血圧変動と心拍変動の関係は,HF領域では正相関関係を示すのに対し,LF領域では関連がなく両者は別の自律神経状況を示した.圧受容体反射はLF領域の血圧変動を抑制的に修飾することより,圧受容体反射の興奮は血圧変動を減少させると考えられ,このことがLF領域における血圧変動と心拍変動の違いを生じさせる機序の一つとして考えられた

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  • A case of massive bleeding from rectal varices treated with endoscopic variceal ligation (EVL) Reviewed

    Takayuki Kojima, Masahiko Onda, Takashi Tajiri, D. Y. Kim, Masahito Toba, Kouji Masumori, Matsuomi Umehara, Hiroshi Yoshida, Yasuhiro Mamada, Nobuhiko Taniai, Hideki Nishikubo, Shigehiko Yokoyama, Sakae Matsuzaki, Noritake Tanaka, Kiyohiko Yamashita, Takumi Aramaki, Yayoi Tetsuoh

    Japanese Journal of Gastroenterology   93 ( 2 )   114 - 119   1996.2

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    DOI： 10.11405/nisshoshi1964.93.114

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  • Prognostic indicators of major cardiac events in patients with asymptomatic coronary artery disease Reviewed

    H Kishida, T Saitoh, J Sano, Y Tada, A Hanashi, N Fukuma, Y Tsukada, M Sekido, H Homma, Y Miyatake, Y Tomita, Y Kusama

    JAPANESE HEART JOURNAL   37 ( 1 )   59 - 72   1996.1

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    We investigated the role of myocardial ischemia in acute myocardial infarction and cardiac death in 253 patients with asymptomatic coronary disease (206 men, 47 women, mean age: 55 +/- 8 years). Patients were divided into two groups: those with angina pectoris with no history of myocardial infarction (AP group, 93 patients) and those with a history of myocardial infarction CMI group, 160 patients). We also examined the usefulness of exercise electrocardiographic and Holter electrocardiographic findings as prognostic indicators of cardiac events. After 24-hour Holter electrocardiograms were obtained in both groups, patients were assigned to subgroups with or without silent myocardial ischemia (SMI) based on the presence or absence of transient ST-segment depression. Prognostic indicators were evaluated by multiple regression analysis. Cardiac events occurred in 26 (10.3%) of 253 patients; in 6 patients these events were fatal. The incidence of cardiac events was significantly higher in the SMI group than in the non-SMI group (16.4% versus 5.6%, P &lt; 0.05). SMI was identified as a significant prognostic indicator in the overall population (p = 0.0088), as were the number of diseased coronary arteries in the AP group (P = 0.0152), and SMI (p = 0.0022) in the MI group. There were 3 deaths related to cardiac events in each group. The mean time from onset of angina pectoris to death was 73 +/- 41 months compared with 33 +/- 43 months in the MI group. Our findings suggest that the severity of the coronary lesion and SMI were important predictors of major cardiac events, and that the mechanism of the onset of cardiac events was different in the AP and MI groups.

    DOI： 10.1536/ihj.37.59

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  • Clinical application of ECG-gated myocardial SPECT with 99mTc-labeled radiopharmaceuticals Invited

    Kumita Shin-ichiro, Mizumura Sunao, Kijima Tetsuji, Kumazaki Tatsuo, Tetsuou Yayoi, Sakai Shunta, Kusama Yoshiki, Munakata Kazuo

    Shinzo   28 ( 1 )   9 - 16   1996

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    DOI： 10.11281/shinzo1969.28.Supplement1_9

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    Other Link： http://search.jamas.or.jp/link/ui/1996206664

  • Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: Possible relevance to cystic fibrosis

    Gottlieb, R.A., Dosanjh, A.

    Proceedings of the National Academy of Sciences of the United States of America   93 ( 8 )   1996

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    DOI： 10.1073/pnas.93.8.3587

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  • Cell acidification in apoptosis

    Gottlieb, R.A.

    Apoptosis   1 ( 1 )   1996

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    DOI： 10.1007/BF00142077

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  • Transglutamination of a single major 43 kDa protein in the cytoskeleton of apoptotic cells from the human T lymphoblastoid line, Jurkat

    Calvo, K.R., Babior, B.M., Gottlieb, R.A.

    Journal of Investigative Medicine   44 ( 1 )   109 - 109   1996

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  • Anti-Fas/Apo-1 monoclonal antibody CH-11 depletes glutathione and kills multidrug-resistant human leukemic cells: Commentary

    Gottlieb, R.A.

    Blood Cells Molecules and Diseases   22 ( 1 )   10 - 10   1996

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1006/bcmd.1996.0003

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  • Preconditioning in rabbit cardiomyocytes: Role of pH, vacuolar proton ATPase, and apoptosis

    Gottlieb, R.A., Gruol, D.L., Zhu, J.Y., Engler, R.L.

    Journal of Clinical Investigation   97 ( 10 )   1996

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    DOI： 10.1172/JCI118683

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  • Events in apoptosis: Acidification is downstream of protease activation and BCL-2 protection

    Meisenholder, G.W., Martin, S.J., Green, D.R., Nordberg, J., Babior, B.M., Gottlieb, R.A.

    Journal of Biological Chemistry   271 ( 27 )   1996

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    DOI： 10.1074/jbc.271.27.16260

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  • Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

    Gottlieb, R.A., Nordberg, J., Skowronski, E., Babior, B.

    Proceedings of the National Academy of Sciences of the United States of America   93 ( 2 )   1996

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    DOI： 10.1073/pnas.93.2.654

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  • Loss of function of cytochrome c in Jurkat cells undergoing Fas-mediated apoptosis

    Krippner, A., Matsuno-Yagi, A., Gottlieb, R.A., Babior, B.

    Journal of Biological Chemistry   271 ( 35 )   1996

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    DOI： 10.1074/jbc.271.35.21629

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  • New paradigm for lymphocyte granule-mediated cytotoxicity: Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

    Froelich, C.J., Orth, K., Turbov, J., Seth, P., Gottlieb, R., Babior, B., Shah, G.M., Bleackley, R.C., Dixit, V.M., Hanna, W.

    Journal of Biological Chemistry   271 ( 46 )   1996

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    DOI： 10.1074/jbc.271.46.29073

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  • 運動誘発心筋虚血における自律神経活動の異常応答について

    哲翁 弥生, 多田 祐美子, 宮武 佳子

    心臓   27 ( Suppl.5 )   54 - 56   1995.8

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    高周波成分(HF)は負荷により低値を示したが,負荷終了後虚血性心疾患群では,負荷前値への回復が遅延した

    DOI： 10.11281/shinzo1969.27.Supplement5_54

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  • 医療薬学とこれからの薬剤師業務 医師の立場から薬剤師へのSuggestion

    哲翁 弥生, 長沢 紘一

    薬事   37 ( 2 )   281 - 285   1995.2

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  • Low-dose dotubamine stress test for the evaluation of cardiac function using ECG-gated SPECT scintigraphy with 99mTc-MIBI Reviewed

    S. Kumita, S. Mizumura, T. Kijima, T. Kumazaki, S. Sakai, Y. Tetsuou, Y. Kusama, K. Munakata

    Kakuigaku   32 ( 1 )   75 - 79   1995

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    Although 201TlCl myocardial scintigraphy has so far been widely used for the evaluation of the viability of the myocardial infarcted area, functional evaluation using low dose dobutamine (DOB) loaded echography also became recently available. We performed 99mTc-MIBI gated SPECT on eight cases of myocardial infarction at rest and low dose (4-6 μg/kg/min) DOB-loading and related data were collected. Next, we calculated myocardial count increase rate (%WT = ES-ED/ED x 100) with left ventricular contraction from end-diastolic (ED) and end-systolic (ES) pictures in short-axial image, and made a comparative examination of regional contractilities at rest and DOB-loading. DOB-loaded echography performed on the same cases at the same dose revealed 15 segments as infarcted area (WM (+)) presenting improvement in wall movement at loading and 5 segments as infarcted area (WM (-)) presenting no such improvement, and %WT at rest and loading were 29.1 ± 6.2 and 33.2 ± 2.4 for (WM (-)) and 26.8 ± 9.8 and 40.0 ± 12.3 for (WM (+)), indicating a significant increase (p &lt
    0.05) at loading. Contractility analysis using MIBI gated SPECT in combined use of DOB-loading was considered as a useful method of examination in view of its reflectionality in the evaluation of the wall movement in DOB-loaded echography and of its high quantitativity.

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  • Effects of nipradilol on the automatic nervous system circadian variation in effort angina.

    Jpn. J. Clin. Pharmacol. Ther.   26 ( 1 )   91 - 92   1995

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    DOI： 10.3999/jscpt.26.91

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  • ECG-gated dual isotope myocardial SPECT with 99mTc-MIBI and 123I- BMIPP in patients with ischemic heart disease Reviewed

    S. I. Kumita, S. Mizumura, T. Kijima, M. Machida, T. Kumazaki, Y. Tetsuou, S. Sakai, Y. Kusama, K. Munakata

    Kakuigaku   32 ( 6 )   547 - 555   1995

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    Simultaneous dual-isotope SPECT with 99mTc-methoxy isobutyl isonitrile (MIBI) and 123I-β-methyl iodophenyl-pentadecanoic acid (BMIPP) was performed in 25 patients with ischemic heart disease. ECG-gated myocardial SPECT was acquired following the injection of MIBI (555 MBq) and BMIPP (148 MBq). Both MIBI and BMIPP scans provided high-quality myocardial images. Then, myocardial count increase rate (%WT = ES -ED/ED x 100) was calculated as an index of left ventricular contraction using MIBI gated SPECT data. The %WT was well correlated with severity scores of both MIBI image (r = -0.70) and BMIPP image (r = -0.72). Thus, ECG-gated dual-isotope SPECT with MIBI and BMIPP was considered to be useful method for assessment of left ventricular contraction as well as myocardial perfusion and fatty acid metabolism.

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  • The acid deoxyribonuclease of neutrophils: A possible participant in apoptosis-associated genome destruction

    Gottlieb, R.A., Giesing, H.A., Engler, R.L., Babior, B.

    Blood   86 ( 6 )   1995

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    DOI： 10.1182/blood.v86.6.2414.bloodjournal8662414

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  • Cell acidification in apoptosis: Granulocyte colony-stimulating factor delays programed cell death in neutrophils by up-regulating the vacuolar H+-ATPase

    Gottlieb, R.A., Giesing, H.A., Zhu, J.Y., Engler, R.L., Babior, B.

    Proceedings of the National Academy of Sciences of the United States of America   92 ( 13 )   1995

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  • 心拍変動周波数解析と圧受容体反射感受性の関係

    哲翁 弥生

    心電図   14 ( 5 )   385 - 385   1994.8

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  • The effect on autonomic nerve activity of Atenolol in a asymptomatic myocardial ischemia case.

    Jpn. J. Clin. Pharmacol. Ther.   25 ( 1 )   29 - 30   1994

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    DOI： 10.3999/jscpt.25.29

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  • Reperfusion injury induces apoptosis in rabbit cardiomyocytes

    Gottlieb, R.A., Burleson, K.O., Kloner, R.A., Babior, B.M., Engler, R.L.

    Journal of Clinical Investigation   94 ( 4 )   1994

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    DOI： 10.1172/JCI117504

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  • The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

    Devary, Y., Gottlieb, R.A., Smeal, T., Karin, M.

    Cell   71 ( 7 )   1992

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/S0092-8674(05)80058-3

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  • Rapid and Preferential Activation of the c-jun Gene during the Mammalian UV Response

    Devary, Y., Gottlieb, R.A., Lau, L.F., Karin, M.

    Molecular and Cellular Biology   11 ( 5 )   1991

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    DOI： 10.1128/MCB.11.5.2804

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  • Inhibition of protein kinase C by a peptide conjugate homologous to a domain of the retroviral protein p15E

    Gottlieb, R.A., Kleinerman, E.S., O{'}Brian, C.A., Tsujimoto, S., Cianciolo, G.J., Lennarz, W.J.

    Journal of Immunology   145 ( 8 )   1990

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  • Phorbol ester treatment stimulates tyrosine phosphorylation of a sea urchin egg cortex protein

    Jiang, W., Gottlieb, R.A., Lennarz, W.J., Kinsey, W.H.

    Journal of Cell Biology   110 ( 4 )   1990

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1083/jcb.110.4.1049

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  • Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction

    Gottlieb, R.A., Lennarz, W.J., Knowles, R.D., Cianciolo, G.J., Dinarello, C.A., Lachman, L.B., Kleinerman, E.S.

    Journal of Immunology   142 ( 12 )   1989

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    Publishing type：Research paper (scientific journal)  

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  • Analysis of the microtubule-binding domain of MAP-2

    Gottlieb, R.A., Murphy, D.B.

    Journal of Cell Biology   101 ( 5 )   1985

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1083/jcb.101.5.1782

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  • The pattern of MAP-2 binding on microtubules: visual enhancement of MAP attachment sites by antibody labeling and electron microscopy

    Gottlieb, R.A., Murphy, D.B.

    Journal of Ultrasructure Research   85 ( 2 )   1983

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/S0022-5320(83)90105-3

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▼display all

Books

  • Nursing care standards for heart failure

    （ Role： Contributor）

    2026.3  （ ISBN:9784796526814 ）

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    Total pages：viii, 326p   Language：Japanese  

    CiNii Books

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  • 総合診療専門研修ハンドブック

    一般社団法人, 基本専門医機構（ Role： Joint editor）

    2020.12 

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  • Patient profile理解のためのカルテの読み方と基礎知識

    吉岡 ゆうこ, 塚田 弥生, 長澤 紘一, 村田 正弘

    じほう  2007.5  （ ISBN:4840736685 ）

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    Total pages：362  

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  • カルテの読み方と基礎知識―Patient profile理解のための

    長沢 紘一, 村田 正弘, 吉岡 ゆうこ, 哲翁 弥生

    じほう  2001.9  （ ISBN:4840728690 ）

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    Total pages：315  

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  • Patient profileの理解のためのカルテの読み方と基礎知識

    長沢 紘一, 村田 正弘, 吉岡 優子, 哲翁 弥生

    薬業時報社  1997.10  （ ISBN:4840722951 ）

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    Total pages：283  

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Presentations

  • 循環器病予防とAI 第三次日本循環器学会5ヵ年計画の意義と予防・啓発領域におけるAI戦略 Invited

    塚田 弥生[哲翁], 太良 修平

    日本循環器病予防学会誌  2026.5  (一社)日本循環器病予防学会

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    Event date： 2026.5

    Language：Japanese  

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  • Sex- and gender-based CVD guidelines in Japan Invited

    Yayoi Tetsuou Tsukada

    2025 SYMPOSIUM K-STAR  2025.11 

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    Event date： 2025.11

    Presentation type：Oral presentation (invited, special)  

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  • 総合診療における多様性とその対応 Invited

    塚田 弥生[哲翁]

    日本病院総合診療医学会雑誌  2025.9  (一社)日本病院総合診療医学会

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    Event date： 2025.9

    Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

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  • Symposium 1: Recognition of Status of CVD in Asian Women Sex Differences in CVD-Related Hospitalization and Mortality in Japan Invited

    Yayoi Tetsuou Tsukada

    Asian Pacific Society of Cardiology  2025.5 

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    Event date： 2025.5

    Language：English   Presentation type：Oral presentation (invited, special)  

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  • 心不全領域の特定行為研修修了看護師の活用を目指して

    塚田(哲翁)弥生

    日本心不全学会学術集会プログラム・抄録集  2023 

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    Event date： 2023

    Presentation type：Oral presentation (invited, special)  

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  • 脈管診療におけるダイバーシティ 持続可能な循環器内科診療に向けて 医師の働き方改革とWell-being Invited

    塚田 弥生[哲翁]

    脈管学  2022.10  (一社)日本脈管学会

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    Event date： 2022.10

    Language：Japanese  

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  • 多様性を配慮した循環器診療の実現に向けて(Towards the Realization of Diversity-Conscious Cardiovascular Medicine) Invited

    Tsukada-Tetsuou Yayoi

    日本医学放射線学会学術集会抄録集  2022.3  (公社)日本医学放射線学会

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    Event date： 2022.3

    Language：Japanese   Presentation type：Oral presentation (invited, special)  

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  • 持続可能な循環器内科診療に向けて-医師の働き方改革とWell-being Invited

    塚田(哲翁)弥生

    脈管学(Web)  2022 

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    Event date： 2022

    Presentation type：Oral presentation (invited, special)  

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  • 両下肢疼痛と好酸球増多から診断に至り早期治療導入で良好な転機を得た好酸球性多発血管炎性肉芽腫症(EGPA)

    丸岡 康信, 米本 崇子, 岳野 光洋, 塚田 弥生

    日本病院総合診療医学会雑誌  2026.2  (一社)日本病院総合診療医学会

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    Event date： 2026.2

    Language：Japanese  

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  • 腸腰筋膿瘍治療中に発症した心房頻拍を合併したメトロニダゾール脳症の一例

    千葉みさこ, 千葉みさこ, 塚田弥生, 米本貴子, 別府佳奈, 別府佳奈, 小貫仁暉, 小貫仁暉, 服部愛

    日本病院総合診療医学会雑誌(Web)  2026 

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  • 感染性心内膜炎に伴う感染性脳動脈瘤から発症した若年性急性硬膜下血腫の一例

    渥美 裕太, 米本 崇子, 小澤 真悠子, 鈴木 貴博, 山崎 遼, 塚田 弥生[哲翁], 土屋 翼, 桑本 健太郎, 村田 智洋

    日本病院総合診療医学会雑誌  2025.9  (一社)日本病院総合診療医学会

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    Event date： 2025.9

    Language：Japanese  

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  • インシデントレポートのテキストマイニングによる医療安全への提言

    米本 崇子, 塚田 弥生[哲翁]

    日本病院総合診療医学会雑誌  2025.9  (一社)日本病院総合診療医学会

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    Event date： 2025.9

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  • 性差医療を再考する-啓蒙・実践への道標- 多様性・公平性・包括性を考慮した循環器診療ガイドラインから得られる示唆と課題(Insights and Challenges from the Guideline on Cardiovascular Practice with Consideration for Diversity, Equity, and Inclusion) Invited

    塚田 弥生[哲翁]

    日本循環器学会学術集会抄録集  2025.3  (一社)日本循環器学会

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    Event date： 2025.3

    Language：English  

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  • 新型コロナウイルス感染症に続発し、全身管理により救命し得たLemierre症候群の一例

    薗田 大二郎, 塚田 弥生

    日本病院総合診療医学会雑誌  2025.2  (一社)日本病院総合診療医学会

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    Event date： 2025.2

    Language：Japanese  

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  • 医師不足地域における勤務義務を有する医師の医師偏在に係る全国横断調査

    上原孝紀, 大平善之, 太田光泰, 小林美亜, 中部貴央, 横川大樹, 李宇, 吉田遼, 井原紫逸, 柳田育孝, 小島淳平, 佐藤瑠璃香, 柴山栄太朗, 塚田弥生

    日本プライマリ・ケア連合学会学術大会(Web)  2025  (一社)日本プライマリ・ケア連合学会

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    Event date： 2025

    Language：Japanese  

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  • 多様性に配慮した脈管疾患診療とは? 大血管疾患の性差疫学 Invited

    野間 さつき, 中山 敦子, 神吉 佐智子, 和田 有子, 渡部 芳子, 保科 克行, 塚田 弥生[哲翁]

    脈管学  2024.10  (一社)日本脈管学会

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    Event date： 2024.10

    Language：Japanese  

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  • 多様性に配慮した脈管疾患診療とは? 「多様性に配慮した循環器診療ガイドライン」について Invited

    塚田 弥生[哲翁]

    脈管学  2024.10  (一社)日本脈管学会

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    Event date： 2024.10

    Language：Japanese  

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  • 成人期医療への移行と病診連携調整に難渋した染色体異常症の一例

    黒沢 明世, 米本 崇子, 五島 祐樹, 塚田 弥生[哲翁]

    日本病院総合診療医学会雑誌  2024.9  (一社)日本病院総合診療医学会

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    Event date： 2024.9

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  • 上行大動脈人工血管置換術後遠隔期に発症した縦隔炎の一例

    角田 寛太, 久保山 有紗, 五島 祐樹, 米本 崇子, 塚田 弥生, 坂本 俊一郎

    日本病院総合診療医学会雑誌  2024.3  (一社)日本病院総合診療医学会

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    Event date： 2024.3

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  • 心臓突然死;診断と予防・治療の最前線(Overview of Strategies to Prevent Sudden Cardiac Death: A Scientific Statement from the JCS Critical Care Promotion Committee)

    西山 知佳, 辻田 賢一, 天野 哲也, 伊藤 智範, 上田 恭敬, 佐久間 理吏, 佐藤 加代子, 谷口 琢也, 田原 良雄, 塚田(哲翁) 弥生, 庭前 野菊, 吉村 聡志, 石見 拓

    日本循環器学会学術集会抄録集  2024.3  (一社)日本循環器学会

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  • 新技術テンソル心電図の総合診療領域における臨床応用の可能性

    塚田(哲翁) 弥生, 岩崎 雄樹, 塚田 信吾, 安武 正弘

    日本病院総合診療医学会雑誌  2023.8  (一社)日本病院総合診療医学会

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    Event date： 2023.8

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  • 病院総合診療医の成長と活躍のためには何が必要か メンバーシップアンケート調査結果を踏まえて

    米本 崇子, 塚田(哲翁) 弥生, 安武 正弘

    日本病院総合診療医学会雑誌  2023.8  (一社)日本病院総合診療医学会

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    Event date： 2023.8

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  • 海外渡航のアスリートの自律神経機能に対する影響について ウェアラブル心電計による心拍変動解析を用いて

    三谷 健人, 塚田 弥生, 安武 正弘

    日本病院総合診療医学会雑誌  2023.8  (一社)日本病院総合診療医学会

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    Event date： 2023.8

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  • 四肢の腫脹と関節症状を初発症状とした後天性血友病Aの2例

    川端 真里佐, 岳野 光洋, 塚田 弥生, 脇田 知志, 安武 正弘

    日本病院総合診療医学会雑誌  2023.8  (一社)日本病院総合診療医学会

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    Event date： 2023.8

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  • COVID-19を契機に発症し、器質的疾患との鑑別を要した統合失調症の一例

    石井 昌嗣, 渡邊 顕弘, 井上 潤一, 川端 真理佐, 塚田 弥生, 安武 正弘

    日本病院総合診療医学会雑誌  2023.8  (一社)日本病院総合診療医学会

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  • 新モデルコアカリキュラム(令和4年)の目標を見据えた理想的かつ教育的な臨床現場構築ための生涯教育の強化事項 臓器専門医のプライマリ・ケア診療の可視化による新モデルコアカリキュラムと連動したリカレント教育の開発

    上原 孝紀, 小林 美亜, 塚田 弥生, 太田 光泰, 大平 善之, 大坪 徹也, 中部 貴央, 野田 和敬, 横川 大樹, 生坂 政臣

    医学教育  2023.7  (一社)日本医学教育学会

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    Language：Japanese  

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  • Application of a Novel ECG Analysis, Tensor Electrocardiogram(TCG) to the Diagnosis of Myocardial Ischemia(タイトル和訳中)

    塚田(哲翁) 弥生, 岩崎 雄樹, 村田 広茂, 塚田 信吾

    日本循環器学会学術集会抄録集  2023.3  (一社)日本循環器学会

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    Event date： 2023.3

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  • 今だからこそ考える:循環器領域における健康の社会的決定要因について(Social Determinants of Health and Cardiovascular Disease) Invited

    鈴木 隆宏, Mizuno Atsushi, Yasui Haruyo, Noma Satsuki, Omori Takashi, Tetsuou Tsukada Yayoi

    日本循環器学会学術集会抄録集  2023.3  (一社)日本循環器学会

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  • 頭痛を契機に診断に至った神経型ベーチェット病の1例 リウマチ性疾患における無菌性髄膜炎の鑑別

    石井 昌嗣, 川端 真里佐, 岳野 光洋, 塚田 弥生, 安武 正弘

    日本病院総合診療医学会雑誌  2023.2  (一社)日本病院総合診療医学会

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    Language：Japanese  

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  • コロナ禍において発熱を主訴に来院した産後女性の進行性悪性腫瘍の2例

    佐藤 路子, 塚田 弥生, 勝俣 範之, 横山 康之, 田邊 智英, 許田 典男, 小林 倫子, 安武 正弘

    日本病院総合診療医学会雑誌  2023.2  (一社)日本病院総合診療医学会

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    Event date： 2023.2

    Language：Japanese  

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  • 病院総合診療医の成長と活躍のためには何が必要か-メンバーシップアンケート調査結果を踏まえて- Invited

    米本崇子, 塚田(哲翁)弥生, 安武正弘

    日本病院総合診療医学会雑誌(Web)  2023 

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  • 頭部CTでの判断が早期治療介入に有用であった脳静脈洞血栓症の一例

    朽名 紗智子, 渡邊 顕弘, 古梅 祐, 佐々木 和馬, 吉野 雄大, 城戸 教裕, 大嶽 康介, 田上 隆, 井上 潤一, 川端 真里佐, 塚田 弥生

    日本病院総合診療医学会雑誌  2022.8  (一社)日本病院総合診療医学会

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    Language：Japanese  

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  • MTX長期内服中に認められた医原性免疫不全関連リンパ増殖性疾患の1例

    佐藤 路子, 塚田 弥生, 勝俣 範之, 岳野 光洋, 許田 典男, 香中 優美, 梶本 雄介

    日本病院総合診療医学会雑誌  2022.8  (一社)日本病院総合診療医学会

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  • ポスト・コロナ時代における海外出張者の健康問題(The Health Issues of Overseas Business Travelers in the post-Corona era)

    Tsukada-Tetsuou Yayoi, Yasutake Masahioto

    日本プライマリ・ケア連合学会学術大会  2022.6  (一社)日本プライマリ・ケア連合学会

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    Language：English  

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  • ポスト・コロナ時代における短期海外ビジネス渡航者の動向と健康課題

    塚田(哲翁)弥生, 岡村律子, 安武正弘

    日本病院総合診療医学会雑誌(Web)  2022  (一社)日本病院総合診療医学会

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  • Trends in Health Issues of Overseas Business Travelers in the post-COVID-19 era

    塚田(哲翁)弥生, 安武正弘

    日本熱帯医学会大会プログラム抄録集  2022 

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  • 急性髄膜炎で発症したベーチェット病の1例

    川端 真里佐, 櫻庭 未多, 酒巻 雅典, 塚田 弥生, 岳野 光洋

    日本内科学会関東地方会  2021.11  日本内科学会-関東地方会

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  • 外科系医師のワーク・ライフバランスの現状と医学教育・研修における可能性について

    海原 純子, 錦谷 まりこ, 早坂 明哲, 藤倉 輝道, 前田 美穂, 塚田 弥生[哲翁]

    日本鼻科学会会誌  2020.12  (一社)日本鼻科学会

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    Event date： 2020.12

    Language：Japanese  

    外科系医師を中心に継続的な就労の要因としてのワーク・ライフバランスを理解し,必要な支援を考えることが本研究の目的である。大学の同窓会や地域の医師会に呼びかけ,現役の医師に対してワーク・ライフバランスとともに,職業環境,家事負担,生活や仕事への満足度,健康状態等に関する調査を行った。また,医学教育による意識の変化を測るため,医学生に対し2年時と卒業前の6年時におけるワーク・ライフバランスの価値について質問した。女性医師は男性医師に比し家事育児による負担感からワーク・ライフコンフリクトの生じる可能性が示された。特に外科系医師は,そうでない医師に比べて時間的な問題で仕事由来のコンフリクトが大きいことが示唆された。医学生のワーク・ライフバランスの重要性に関する意見は,女子医学生のほうが重要と考えるものが多かったが,卒前の6年時の調査結果で男女間の差は小さくなった。家事育児の性別役割分担への考えは,生育家庭から影響を受けることが示唆され,労働時間など職場環境の改善のほか,大学の医学教育の充実も,医師などの専門職の就労継続に効果のある可能性が示唆された。(著者抄録)

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    Other Link： https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2020&ichushi_jid=J01675&link_issn=&doc_id=20210112380006&doc_link_id=10.7248%2Fjjrhi.59.325&url=https%3A%2F%2Fdoi.org%2F10.7248%2Fjjrhi.59.325&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • 首都圏における高齢者心不全患者の病診連携について 地域医療機関のアンケート結果から

    塚田 弥生[哲翁], 安武 正弘

    日本病院総合診療医学会雑誌  2020.2  (一社)日本病院総合診療医学会

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  • 2018-2019年シーズン流行期の成人ヒトパルボウイルスB19感染症の臨床的特徴

    吉村 祐亮, 柴山 雅行, 岡村 律子, 塚田 弥生[哲翁], 望月 徹, 岳野 光洋, 松田 潔, 安武 正弘

    日本病院総合診療医学会雑誌  2019.11  (一社)日本病院総合診療医学会

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    Language：Japanese  

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  • 新専門医制度における若手循環器医師の育成と問題点 循環器と一般内科の二つの専門医認定を受けるための柔軟な研修プログラム(Flexible Training Program for Double Board Certifications with Cardiology and General Medicine)

    哲翁 弥生[塚田], 佐藤 直樹, 安武 正弘, 清水 渉

    日本循環器学会学術集会抄録集  2019.3  (一社)日本循環器学会

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  • 骨粗鬆症関連後彎症は心機能を障害するか(Does Osteoporosis-related Kyphosis Impair Cardiac Function?)

    Tokita Miwa, Tetsuou-Tsukada Yayoi, Nakamura Yuuki, Kubota Yoshiaki, Aoyama Rie, Tokita Yukichi, Asai Kuniya, Shimizu Wataru

    日本循環器学会学術集会抄録集  2017.3  (一社)日本循環器学会

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  • The Usefulness of T1 Mapping for Evaluation of Myocardial Fibrosis in Patients with Cardiomyopathy

    INUI Keisuke, ASAI Kuniya, KUBOTA Yoshiaki, MURAI Koji, TETSUOU-TSUKADA Yayoi, SHIMIZU Wataru

    Circulation Journal  2016 

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  • 高熱に伴い完全房室ブロックの補充調律が維持され解熱と共にQT延長が顕性化したTorsade de Pointes発症症例

    中村有希, 岩崎雄樹, 藤本雄飛, 坪井一平, 太良修平, 吉川雅智, 哲翁(塚田)弥生, 清水渉

    日本循環器学会関東甲信越地方会(Web)  2016 

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  • Incidence of Hypoglycemia in Coronary Artery Disease Patients Receiving No Antidiabetic Agents

    KUBOTA Yoshiaki, TAKANO Hitoshi, ONODERA Kenta, SUZUKI Keishi, NAKAMURA Yuuki, SANGEN Hideto, INUI Keisuke, AOYAMA Rie, TARA Shuhei, TOKITA Yukichi, YAMAMOTO Takeshi, TETSUOU-TSUKADA Yayoi, ASAI Kuniya, SHIMIZU Wataru

    Circulation Journal  2016 

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  • 心不全増悪をもたらす非心臓因子(脳、肺) COPD合併心不全患者における治療戦略

    久保田 芳明, 浅井 邦也, 知念 大悟, 吉永 綾, 村井 綱児, 吉川 雅智, 塚田 弥生, 清水 渉

    日本心臓病学会学術集会抄録  2015.9  (一社)日本心臓病学会

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  • 左心耳内巨大血栓から脾梗塞を発症した肥大型心筋症の一例

    厚見佳彦, 吉川雅智, 西郡卓, 知念大悟, 林明聡, 哲翁(塚田)弥生, 清水渉

    日本循環器学会関東甲信越地方会(Web)  2015 

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  • Chronic Obstructive Pulmonary Disease Advances Left Ventricular Diastolic Dysfunction

    KUBOTA Yoshiaki, ASAI Kuniya, CHINEN Daigo, YOSHINAGA Aya, INUI Keisuke, NAKAMURA Shunichi, MURAI Koji, YOSHIKAWA Masatomo, TETSUOU-TSUKADA Yayoi, HIROKI Hayashi, SAITO Yoshinobu, AZUMA Arata, GEMMA Akihiko, SHIMIZU Wataru

    Circulation Journal  2015 

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  • T1 Mapping in Nonischemic Cardiomyopathy at Cardiac Magnetic Resonance: Comparison with Endomyocardial Biopsy

    INUI Keisuke, ASAI Kuniya, SAITOH Tsunenori, KUBOTA Yoshiaki, NAKAMURA Shunichi, MURAI Koji, KATOH Koji, TAKANO Hitoshi, TETSUOU-TSUKADA Yayoi, SHIMIZU Wataru

    Circulation Journal  2015 

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  • Prognostic Value of Extracellular Volume Fraction in Non-ischemic Heart Failure Patients

    INUI Keisuke, ASAI Kuniya, KUBOTA Yoshiaki, NAKAMURA Shunichi, MURAI Koji, KATOH Koji, TAKANO Hitoshi, TETSUOU-TSUKADA Yayoi, SHIMIZU Wataru

    Circulation Journal  2015 

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  • 非心臓関連併存疾患がHFpEFに与える影響

    久保田 芳明, 浅井 邦也, 知念 大悟, 吉永 綾, 乾 恵輔, 中村 俊一, 村井 綱児, 吉川 雅智, 加藤 浩司, 塚田 弥生, 清水 渉

    日本心臓病学会学術集会抄録  2014.9  (一社)日本心臓病学会

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  • インターベンション循環器専門医の女性医師における勤務環境の現状と課題 なぜインターベンション心臓電気生理学領域に女性がほとんどいないのか?(Current Status and Problems of Their Working Conditions for Female Interventional Cardiologists Why So Few Women in Interventional Cardiac Electrophysiology?)

    Okazaki Reiko, Tetsuou-Tsukada Yayoi, Iwasaki Yuki, Miyauchi Yasushi, Igawa Osamu, Atarashi Hirotsugu, Shimizu Wataru

    Circulation Journal  2014.3  (一社)日本循環器学会

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  • The Impact of β-blocker and Inhaled Tiotropium on Long-term Outcomes in Congestive Heart Failure Patients with Chronic Obstructive Pulmonary Disease

    KUBOTA Yoshiaki, ASAI Kuniya, YOSHINAGA Aya, KOMIYAMA Hidenori, MURAI Koji, YOSHIKAWA Masatomo, TETSUOU-TSUKADA Yayoi, SHIMIZU Wataru

    Circulation Journal  2014 

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  • Usefulness of Myocardial Extracellular Volume (ECV) Measurement by Cardiovascular Magnetic Resonance (CMR) for Detecting Cardiac Remodeling

    INUI Keisuke, KATOH Koji, KUBOTA Yoshiaki, MURAI Koji, TETSUOU-TSUKADA Yayoi, ASAI Kuniya, KUMITA Shinichiro, SHIMIZU Wataru

    Circulation Journal  2014 

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  • 女性心臓病専門医が辞めることなくキャリア継続させる上での問題と解決法 地域性を考慮した女性医師の継続的キャリアへの支援(Problems and Solutions for Female Cardiologists to Continue Their Career without Quitting Support for Continuous Career of Women Doctors Considering Regional Characteristics)

    Tetsuoh-Tsukada Yayoi, Mizuno Kyoichi

    Circulation Journal  2013.3  (一社)日本循環器学会

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  • 心血管疾患における性差医療 現状と将来展望 女性における心血管疾患の最近の傾向 冠疾患集中治療室に入室した患者に関する24年間の分析(Gender-specific Medicine in Cardiovascular Disease: Current Status and Future Perspectives: Recent Trends of Cardiovascular Disease in Women: A Twenty-Four Year Analysis of the Patients Hospitalized for Coronary Care Unit)

    Tetsuoh-Tsukada Yayoi, Tokita Yukichi, Mizuno Kyoichi, Yamamoto Takeshi, Tanaka Keiji

    Circulation Journal  2012.3  (一社)日本循環器学会

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  • 高齢者RS3PE症候群の1例

    加藤 祐子, 林 寛子, 小野 いすず, 田辺 浩子, 福本 裕子, 塚田 弥生, 八島 正明, 安武 正弘, 川口 信子, 水野 杏一

    日本老年医学会雑誌  2011.7  (一社)日本老年医学会

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  • Sulfaphenazole Mediates Cardioprotection Through Preconditioning and Autophagy

    Chengqun Huang, Yayoi Tetsuo Tsukada, Cynthia N. Perry-Garza, Robert M. Mentzer, Roberta A. Gottlieb

    CIRCULATION RESEARCH  2008.8  LIPPINCOTT WILLIAMS & WILKINS

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    Language：English   Presentation type：Oral presentation (general)  

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  • 先行虚血発作による後続発作に対する虚血重症度軽減, 抗不整脈作用 : 異型狭心症における検討

    草間 芳樹, 福間 祐美子, 及川 恵子, 塚田 弥生, 佐野 純子, 福間 長知, 岸田 浩, 高野 照夫

    心電図 = Electrocardiology  2002.3 

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  • Relationship between the interval of ischemic episodes and severity of ischemia in patients with variant angina

    Y Fukuma, T Saitoh, H Tanabe, H Takahashi, K Oikawa, A Hanashi, Y Tsukada, J Sano, N Fukuma, Y Kusama, H Kishida

    CIRCULATION  1998.10  LIPPINCOTT WILLIAMS & WILKINS

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  • 0408 冠動脈疾患における流血中Macrophage Colony Stimulating Factorと心事故発生

    斉藤 勉, 田辺 浩子, 高橋 啓, 及川 恵子, 馬渕 浩輔, 富村 正登, 葉梨 亜矢, 塚田 弥生, 多田 祐美子, 佐野 純子, 福間 長知, 草間 芳樹, 岸田 浩, 早川 弘一

    Japanese circulation journal  1998.2  社団法人日本循環器学会

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  • 0677 異型狭心症における発作間隔と発作重症度の関係

    多田 裕美子, 斉藤 勉, 田辺 浩子, 高橋 啓, 及川 恵子, 葉梨 亜矢, 塚田 弥生, 佐野 純子, 福間 長知, 草間 芳樹, 岸田 浩, 早川 弘一

    Japanese circulation journal  1998.2  社団法人日本循環器学会

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  • P003 糖尿病における微小血管病変の発現とMacrophage Colony Stimulating Factor(M-CSF)

    田辺 浩子, 斉藤 勉, 高橋 啓, 及川 恵子, 葉梨 亜矢, 塚田 弥生, 多田 祐美子, 佐野 純子, 福間 長知, 岸田 浩, 早川 弘一

    Japanese circulation journal  1998.2  社団法人日本循環器学会

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  • 0304 高血圧性心疾患における心筋肥大様式と流血中MacrophageColony Stimulating Factor(M-CSF)およびTransforming Growth Factorβ1(TGF-β1)との関連性

    高橋 啓, 斉藤 勉, 田辺 浩子, 及川 恵子, 馬渕 浩輔, 富村 正登, 葉梨 亜矢, 塚田 弥生, 多田 祐美子, 佐野 純子, 福間 長知, 本間 博, 早川 弘一, 岸田 浩

    Japanese circulation journal  1998.2  社団法人日本循環器学会

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  • P368 血管増殖性因子と心臓自律神経活動

    斉藤 勉, 岸田 浩, 葉梨 亜矢, 多田 祐美子, 哲翁 弥生, 佐野 純子, 福間 長知, 草間 芳樹, 早川 弘一

    Japanese circulation journal  1997.3  社団法人日本循環器学会

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  • ECG-gated myocardial SPECT with Tc-99m-MIBI and I-123-BMIPP in patients with ischemic heart disease

    S Kumita, S Mizumura, K Cho, T Kijima, M Ishihara, T Kumazaki, Y Tetsuou, Y Kusama, K Munakata

    JOURNAL OF NUCLEAR MEDICINE  1996.5  SOC NUCLEAR MEDICINE INC

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  • Relationship between Low Frequency Component of Heart Rate Variability and Hemodynamic Parameters

    1996.3 

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  • 96) 著明な多尿と電解質異常を認めた腎血管性高血圧の一例(日本循環器学会 第155回関東甲信越地方会)

    哲翁 弥生, 宮武 佳子, 上田 洋一, 後藤 正道, 田中 邦夫, 鈴木 健, 大津 文雄, 長澤 紘一

    Japanese circulation journal  1996.2  社団法人日本循環器学会

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  • 0365 異型狭心症の一過性心筋虚血発作における心臓自律神経系の寄与とnifedipineの効果

    佐野 純子, 斉藤 勉, 岸田 浩, 葉梨 亜矢, 塚田 弥生, 多田 祐美子, 福間 長知, 草間 芳樹, 早川 弘一

    Japanese circulation journal  1996.2  社団法人日本循環器学会

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  • P514 運動負荷時不整脈発現における圧受容体反射感受性の意義

    馬淵 浩輔, 福間 長知, 松田 裕之, 富村 正登, 葉梨 亜矢, 多田 祐美子, 哲翁 弥生, 佐野 純子, 斉藤 勉, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1996.2  社団法人日本循環器学会

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  • 狭心症における虚血発作と体液性因子との関連および治療について

    斉藤 勉, 岸田 浩, 多田 祐美子, 哲翁 弥生, 佐野 純子, 福間 長知, 草間 芳樹, 宗像 一雄, 早川 弘一

    循環制御 = CIRCULATION CONTROL  1995.6 

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  • 1320 ドブタミン(DOB)負荷99mTc-MIBI心拍同期心筋シンチグラフィを用いた心筋viabilityの定量的評価 : ドブタミン負荷心エコーとの対比

    酒井 俊太, 草間 芳樹, 本間 博, 哲翁 弥生, 佐野 純子, 宗像 一雄, 岸田 浩, 早川 弘一, 汲田 伸一郎, 隈崎 達夫

    Japanese circulation journal  1995.3  社団法人日本循環器学会

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  • P143 心拍変動の成因 : 圧受容体反射感受性試験による検討

    哲翁 弥生, 福間 長知, 馬渕 浩輔, 笠神 康平, 葉梨 亜矢, 多田 祐美子, 佐野 純子, 斉藤 勉, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1995.3  社団法人日本循環器学会

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  • 1107 糖尿病におけるQT間隔延長と心臓自律神経活動^<123>I-MIBG心交感神経Imagingと心拍変動周波数解析を用いて

    哲翁 弥生, 葉梨 亜矢, 多田 祐美子, 福間 長知, 斉藤 勉, 太田 真夫, 宗像 一雄, 岸田 浩, 早川 弘一, 汲田 伸一郎, 隅崎 達夫

    Japanese circulation journal  1995.3  社団法人日本循環器学会

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  • P350 心不全患者における圧受容体反射感受性と体液性因子の関係

    多田 祐美子, 福間 長知, 場淵 浩輔, 笠神 康平, 富村 正登, 葉梨 亜矢, 哲翁 弥生, 斉藤 勉, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1995.3  社団法人日本循環器学会

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  • 0090 外因的Insulin誘発性心筋虚血出現の機序

    斉藤 勉, 岸田 浩, 多田 祐美子, 哲翁 弥生, 佐野 純子, 福間 長知, 草間 芳樹, 早川 弘一

    Japanese circulation journal  1995.3  社団法人日本循環器学会

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  • The prognostic significance of exercise thalium 201 stress test in patients with silent myocardial ischemia

    Hanashi Aya, Saitoh Tsutomu, Kishida Hiroshi, Tetsuou Yayoi, Tada Yumiko, Miyatake Yoshiko, Sano Junko, Fukuma Nagaharu, Hayakawa Hirokazu

    Japanese circulation journal  1994.6  Japanese Circulation Society

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  • ^<123>I-MIBG心筋SPECTは糖尿病の臨床評価に有用か : 第58回日本循環器学会学術集会

    佐野 純子, 哲翁 弥生, 山崎 佳子, 斉藤 勉, 宗像 一雄, 岸田 浩, 太田 真夫, 大竹 稔, 早川 弘一, 汲田 伸一郎, 隈崎 達夫

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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  • 冠動脈疾患における一過性心筋虚血出現の日内リズムへの内的要因の寄与 : 第58回日本循環器学会学術集会

    斉藤 勉, 岸田 浩, 山崎 佳子, 多田 祐美子, 哲翁 弥生, 佐野 純子, 福間 長知, 草間 芳樹, 早川 弘一

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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  • 三検出器型ガンマカメラを用いた^<99m>Tc-MIBI心拍同期心筋シンチグラフィの有用性 : 第58回日本循環器学会学術集会

    汲田 伸一郎, 林 宏光, 川俣 博志, 隈崎 達夫, 哲翁 弥生, 草間 芳樹, 宗像 一雄

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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    Event date： 1994.3

    Language：Japanese  

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  • 耐糖能障害の圧受容体感受性に及ぼす影響 : 第58回日本循環器学会学術集会

    福間 長知, 富村 正登, 哲翁 弥生, 多田 祐美子, 山崎 佳子, 佐野 純子, 斉藤 勉, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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    Event date： 1994.3

    Language：Japanese  

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  • Silent Myocardial Ischemiaの予後推定におけるタリウム負荷心筋シンチグラムの意義 : 第58回日本循環器学会学術集会

    葉梨 亜矢, 斎藤 勉, 哲翁 弥生, 多田 祐美子, 宮武 佳子, 佐野 純子, 福間 長知, 岸田 浩, 早川 弘一

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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    Event date： 1994.3

    Language：Japanese  

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  • 冠攣縮性狭心症における体液因子の生体リズムにおよぼす影響 : 第58回日本循環器学会学術集会

    多田 祐美子, 斉藤 勉, 葉梨 亜矢, 哲翁 弥生, 山崎 佳子, 佐野 純子, 福間 長知, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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    Event date： 1994.3

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  • 運動負荷時血圧・心拍応答に対する圧受容体反射の調節機序について : 第58回日本循環器学会学術集会

    富村 正登, 福間 長知, 哲翁 弥生, 多田 祐美子, 山崎 佳子, 佐野 純子, 斎藤 勉, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1994.3  社団法人日本循環器学会

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    Event date： 1994.3

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  • 急性心筋梗塞発症の日内リズムへの冠攣縮の関与 : ポスター発表 : 第57回日本循環器学会学術集会

    国見 聡宏, 斉藤 勉, 葉梨 亜矢, 多田 祐美子, 哲翁 弥生, 山崎 佳子, 佐野 純子, 福間 長知, 草間 芳樹, 宗像 一雄, 岸田 浩, 早川 弘一

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 運動誘発心筋虚血における自律神経活動の異常応答 : 口述発表 : 第57回日本循環器学会学術集会

    哲翁 弥生, 斉藤 勉, 葉梨 亜矢, 多田 祐美子, 山崎 佳子, 佐野 純子, 福間 長知, 岸田 浩, 早川 弘一, 笹川 新, 島井 新一郎

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 本態性高血圧症例における陰性U波の出現機序 : 血中α-HANPと心臓RIアンギオグラフィー(心RI)による検討 : ポスター発表 : 第57回日本循環器学会学術集会

    福間 長知, 岸田 浩, 八幡 丞子, 葉梨 亜矢, 哲翁 弥生, 多田 祐美子, 山崎 佳子, 佐野 純子, 斉藤 勉, 早川 弘一

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 自律神経活動の周期変動から推定した異型狭心症におけるCa拮抗薬の作用機序 : 口述発表 : 第57回日本循環器学会学術集会

    山崎 佳子, 斎藤 勉, 八幡 丞子, 葉梨 亜矢, 哲翁 弥生, 多田 祐美子, 佐野 純子, 国見 聡宏, 福間 長知, 岸田 浩, 早川 弘一

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 血液透析時低血圧発現機序とその規定因子についてRlアンギオグラフィと心拍変動周波数分析を用いて : 口述発表 : 第57回日本循環器学会学術集会

    哲翁 弥生, 斉藤 勉, 八幡 丞子, 多田 祐美子, 山崎 佳子, 佐野 純子, 福間 長知, 岸田 浩, 早川 弘一, 笹川 新, 島井 新一郎

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 心筋梗塞患者の心室性期外収縮(VPC)出現の心拍反応性と日内変動について : ポスター発表 : 第57回日本循環器学会学術集会

    葉梨 亜矢, 斉藤 勉, 八幡 丞子, 哲翁 弥生, 多田 祐美子, 山崎 佳子, 佐野 純子, 国見 聡宏, 福間 長知, 岸田 浩, 早川 弘一

    Japanese circulation journal  1993.3  社団法人日本循環器学会

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    Event date： 1993.3

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  • 刺激伝導系に高度の脂肪浸潤を認めたQT延長症候群の1例 : 日本循環器学会第132回関東甲信越地方会

    哲翁 弥生, 今泉 孝敬, 洪 芳樹, 鈴木 健, 大津 文雄, 針谷 吉人, 長澤 紘一, 前田 昭太郎, 早川 弘一

    Japanese circulation journal  1992.5  社団法人日本循環器学会

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    Event date： 1992.5

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  • 冠動脈疾患の予後におよぼす自律神経活動の影響

    佐野 純子, 斎藤 勉, 岸田 浩, 葉梨 亜矢, 多田 祐美子, 哲翁 弥生, 安武 正弘, 福間 長知, 早川 弘一

    Japanese circulation journal  1992.3  社団法人日本循環器学会

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    Event date： 1992.3

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  • 労作狭心症患者における狭心痛閾値上昇の機序 : 体性感覚誘発位法(SSEP法)による検討

    福間 長知, 岸田 浩, 哲翁 弥生, 多田 祐美子, 佐野 純子, 斉藤 勉, 早川 弘一

    Japanese circulation journal  1992.3  社団法人日本循環器学会

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    Event date： 1992.3

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  • 糖尿病におけるQT間隔延長と心臓自律神経活動 123I-MIBG心交感神経Imagingと心拍変動周波数解析を用いて

    哲翁 弥生

    第59回日本循環器学会学術集会  1995.3 

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Research Projects

  • 健康日本21（第3次）推進に資する住環境改善による睡眠と生活習慣病の実装モデル構築：自然に健康になれる環境のデザイン

    Grant number：26FA1008  2026.4 - 2030.3

    厚生労働省  厚生労働科学研究費補助金  （循環器疾患・糖尿病等生活習慣病対策総合研究事業）

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    Authorship：Coinvestigator(s) 

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  • テンソル心電図解析技術による致死性不整脈発生予知システムの構築

    Grant number：25K11420  2025.4 - 2028.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    岩崎 雄樹, 塚田 弥生, 塚田 信吾

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    Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）

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  • 健康寿命の延伸および健康格差の縮小に影響を与える要因の解明御為の研究

    Grant number：25FA1005  2025.4 - 2028.3

    厚生労働省  厚生労働科学研究費補助金  （循環器疾患・糖尿病等生活習慣病対策総合研究事業）

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    Authorship：Coinvestigator(s) 

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  • 新技術テンソル心電図による虚血心筋障害検出の基礎的検討

    Grant number：24K10585  2024.4 - 2027.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    塚田 弥生

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    Grant amount：\4420000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）

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  • テンソル心電図による遺伝性心疾患の高精度早期自動診断システムの確立

    2024 - 2025.3

    国立研究開発法人 日本医療研究開発機構  令和6年度 医療機器等研究成果展開事業（チャレンジタイプ） 

    塚田(哲翁) 弥生

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    Authorship：Principal investigator 

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  • インシリコモデルとテンソル心電図解析による早期再分極症候群の不整脈リスク分析

    Grant number：22K08217  2022.4 - 2025.3

    日本学術振興会  科学研究費助成事業 基盤研究(C)  基盤研究(C)

    岩崎 雄樹, 杉浦 清了, 塚田 弥生, 塚田 信吾

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    Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）

    初年度は、テンソル心電図解析システムの基盤を作るため、デジタル心電図データの抽出方法の確立および紙媒体の心電図波形からのデジタル化を行っている。特に紙媒体の心電図データのデジタル化からテンソル心電図解析まで自動化するプログラムを作成している。正常心電図群と早期再分極症候群群のデータベース構築のための準備を進めている。既存の心電図データをもとに初期の解析を行いテンソル心電図解析プログラムの調整を行うとともに、早期再分極症候群のテンソル心電図解析を行った。また、心電図のST部分に関するテンソル心電図解析の有用性を明らかにするために、心筋虚血症例についても同様に解析を行った。テンソル心電図解析には2種類の解析方法（Separate法とBulk法）があり、両者の比較と利点と欠点についての分析を行っている。
    2023年3月に第87回日本循環器学会学術集会のシンポジウムでテンソル心電図解析の概要および初期の解析結果について『Novel wearable device with Tensor ECG for Comprehensive Monitoring in the Patients with Heart Failure』という演題名で報告した。
    今後は、日本人の年齢別・性別ごとの正常心電図のデータベースを作成し、テンソル心電図解析を行うことにより、各パラメーターの正常値について明らかにしていく予定である。

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  • Evaluation of the cardiovascular system of overseas business persons using wearable terminals and its application for work management

    2019.4 - 2022.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research 

    Yayoi Tetsuou Tsukada

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    Grant type：Competitive

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  • ホルター心電図運動療法支援システムの開発による糖尿病症例の心疾患進展防止効果

    2011 - 2012

    鈴木謙三記念医科学応用研究財団  調査研究助成金 

    塚田(哲翁)弥生

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    Grant type：Competitive

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  • 心筋細胞のSphingosine 1-phosphate受容体によるカルシウムイオン代謝への影響

    2006 - 2007

    日本女医会  学術研究助成 

    塚田(哲翁)弥生

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    Grant type：Competitive

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  • DPCとタイムスタディを用いた臓器専門医のプライマリ・ケア診療可視化に基づく医師偏在指標の開発

    厚生労働省  厚生労働科学研究費補助金  地域医療基盤開発推進研究事業

    上原 孝紀

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    Authorship：Coinvestigator(s) 

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Teaching Experience

  • Cardiovascular Medicine

    Institution：Nippon Medical School

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  • General Medicine

    Institution：Nippon Medical School

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