2025/09/03 更新

写真a

サノ トウミ
佐野 透美
Sano Tomi
所属
武蔵小杉病院 小児科 助教
職名
助教
外部リンク

論文

  • The Incidence of Pediatric Invasive Bacterial Diseases in Nippon Medical School Chiba Hokusoh Hospital before and after the Introduction of Conjugate Vaccines.

    Toumi Sano, Tamaho Suzuki, Ayako Nishigori, Chiharu Miyatake, Shinya Koizumi, Kiyohiko Kaizu, Atsushi Fujita, Mitsuhiro Kamisago, Bin Chang, Naruhiko Ishiwada, Takeshi Asano

    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   85 ( 1 )   34 - 38   2018年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    The introduction of the Haemophilus influenzae type b (Hib) vaccine and the 7-valent pneumococcal conjugate vaccine (PCV7) has led to dramatic reductions in cases of invasive H. influenzae disease and invasive pneumococcal disease (IPD). After the introduction of the PCV7 and the 13-valent pneumococcal conjugate vaccine (PCV13), the number of children with IPD markedly decreased in our hospital. However, since 2015, three children with IPD have been admitted to our hospital. We analyzed the serotype, multilocus sequence type, and antimicrobial susceptibility of Streptococcus pneumoniae strains isolated in these newly diagnosed cases. The strains were serotypes 7F and 12F. In addition, we analyzed the incidence of invasive bacterial disease before and after the introduction of conjugate vaccines and found no change in the incidences. We found that cases of IPD and invasive H. influenzae disease clearly decreased following the introduction of the PCV7, the PCV13, and the Hib vaccine, as well as disease caused by antibiotic-resistant strains.

    DOI: 10.1272/jnms.2018_85-5

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