Updated on 2025/03/26

写真a

 
Yasui Daisuke
 
Affiliation
Musashikosugi Hospital, Department of Clinical Radiology, Senior Assistant Professor
Title
Senior Assistant Professor
External link

Papers

  • Preemptive Embolization of Abdominal Aortic Aneurysm Sac Side Branch Arteries Promotes Early Sac Shrinkage after Endovascular Aneurysm Repair 1. International journal

    Tatsuo Ueda, Ryutaro Fujitsuna, Hidemasa Saito, Daisuke Yasui, Fumie Sugihara, Takahiko Mine, Sayaka Shirai, Taiga Matsumoto, Jiro Kurita, Yosuke Ishii, Hiromitsu Hayashi, Shin-Ichiro Kumita

    Annals of vascular surgery   109   9 - 19   2024.12

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    BACKGROUND: The association between the occlusion rate of the side branch arteries branching from the abdominal aortic aneurysm sac and aneurysm sac shrinkage is unclear. We aimed to evaluate the efficacy of preemptive embolization of multiple side branch arteries branching from the abdominal aortic aneurysm sac in early aneurysm sac shrinkage after endovascular aneurysm repair. METHODS: Patients undergoing endovascular aneurysm repair of abdominal aortic aneurysms, with or without preemptive embolization of multiple side branch arteries, including the inferior mesenteric artery and lumbar arteries, between January 2016 and August 2021, were retrospectively evaluated. Preemptive embolization was introduced at our institution in January 2018 and has been performed in all patients who undergo endovascular aneurysm repair since then. We compared occlusion rates of the side branch arteries, frequency of type 2 endoleaks, changes in aneurysm sac size, percentage of aneurysm sac size decrease, and frequency of reduction in the aneurysm sac diameter by > 5 mm. RESULTS: The study included 43 patients in the embolization group and 20 in the nonembolization group. Preemptive embolization was successfully performed without any ischemic complications. The total occlusion rate of side branch arteries was significantly higher in the embolization group than in the nonembolization group (70.2% vs. 29.3%, P < 0.05). At 24 months of follow-up, the type 2 endoleak frequency was significantly lower in the embolization group than in the nonembolization group (6.9% vs. 31.6%, P < 0.05). The frequency of reduction in the aneurysm sac diameter by > 5 mm was significantly higher in the embolization group than in the nonembolization group at 24 months (62.1% vs. 31.6% P < 0.05). The optimal cutoff value for the total occlusion rate of the side branch arteries to achieve reduction in the aneurysm sac diameter by > 5 mm at 24 months, after endovascular aneurysm repair, was 66.7% in all patients (area under the curve = 0.634; sensitivity = 62.5%; specificity = 70.8%). These findings suggest that occluding 66.7% or more of the side branch arteries may result in early aneurysmal shrinkage. CONCLUSIONS: Preemptive embolization of multiple side branch arteries, branching from the abdominal aortic aneurysm sac, may contribute to early aneurysm sac shrinkage; this may serve as a marker for fewer late complications after endovascular aneurysm repair.

    DOI: 10.1016/j.avsg.2024.06.024

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  • Early and Post-Treatment Imaging Findings in Perineural Spread: A Pathway to Diffuse Muscle Metastasis in Recurrent Bladder Carcinoma.

    Yoshimitsu Honda, Tetsuro Sekine, Ryoji Kimata, Norio Motoda, Keigo Takahashi, Aya Yamane, Daisuke Yasui, Eigo Kodani, Taro Ichikawa, Shinichiro Kumita

    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   91 ( 3 )   333 - 338   2024.7

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    Perineural spread (PNS) from pelvic carcinoma has been regarded as a pathway to muscle and bone metastasis. However, few cases have been reported, especially in patients with bladder carcinoma. In the present report, we discuss a case of diffuse cancer involvement in the muscle 5 years after radical cystectomy for advanced bladder carcinoma. Careful observation of temporal changes on medical images confirmed PNS as the pathway to muscle metastasis (i.e., primary PNS). Our report presents early and post-treatment CT, MRI and FDG-PET/CT findings of PNS from the bladder carcinoma.

    DOI: 10.1272/jnms.JNMS.2024_91-301

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  • An experimental study on the diagnostic advantage of dual-energy computed tomography over single-energy scan to evaluate the treatment effect following transcatheter arterial chemoembolization. International journal

    Aya Yamane, Daisuke Yasui, Hiroshi Itoh, Masayuki Kobayashi, Shin-Ichiro Kumita

    PloS one   19 ( 11 )   e0313543   2024

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    OBJECTIVES: We assessed the diagnostic advantage of dual-energy computed tomography (DECT) over single-energy computed tomography (SECT) to evaluate lipiodol accumulation in target lesions following transcatheter arterial chemoembolization (TACE). METHODS: TACE was performed in 10 rabbits in whom the VX2 tumor was implanted in their left liver lobes. The miriplatin-lipiodol mixture was injected into the common hepatic artery. All rabbits were sacrificed 2 days after TACE, and the liver was harvested. CT was performed using both single-energy and dual-energy scan modes. The specimen was stained with Oil Red O to evaluate lipiodol accumulation; this was considered the reference standard. Mutual information (MI) was used to evaluate the significance of radiological-pathological correlation. Estimated iodine content values on iodine material density images were compared with actual values obtained using mass spectroscopy. RESULTS: Mean MI values were 0.69, 0.32, 0.83, 0.72, 0.65, and 0.58 for single-energy scan; iodine density images; and virtual monoenergetic images for energy levels of 40, 60, 80, and 100 keV, respectively. The MI value of the monochromatic image (40 keV) was the highest among all sequences. However, this was not significant compared with the single-energy scan (p = 0.81). A significant correlation was observed between the estimated and actual values of iodine content (Pearson's product moment coefficient = 0.70, p = 0.023). CONCLUSION: More accurate and quantitative lipiodol evaluation in targeted tumors after TACE can be achieved by applying DECT rather than SECT.

    DOI: 10.1371/journal.pone.0313543

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  • Two Cases of Bronchial Artery Racemose Hemangioma Successfully Treated with Bronchial Artery Embolization.

    Natsuki Hashiba, Ryuta Nakae, Daisuke Yasui, Masaaki Inoue, Riko Maejima, Toru Takiguchi, Hidetaka Onda, Shiei Kim, Shoji Yokobori

    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   89 ( 6 )   594 - 598   2023.2

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    Rupture of a racemose hemangioma causing dilatation and tortuosity of the bronchial artery can result in massive bleeding and respiratory failure. Bronchial artery embolization (BAE) can treat this life-threatening condition, as we show in two cases. The first case was of an 89-year-old female complaining of sudden-onset chest and back pain. Bronchial artery angiography demonstrated a racemose hemangioma with a 2 cm aneurysm. The second case was of a 50-year-old male with hemoptysis and dyspnea, eventually requiring intubation. Bronchial arteriography showed a racemose hemangioma and a bronchial artery-pulmonary arterial fistula. BAE was successfully performed in both cases, with no recurrent hemorrhage. Therapeutic interventions in bronchial artery racemose hemangiomas include lobectomy or segmentectomy, bronchial arterial ligation, and BAE. BAE should be considered as first-line therapy for bleeding racemose hemangiomas of the bronchial artery because of its low risk of adverse effects on respiratory status, minimal invasiveness, and faster patient recovery.

    DOI: 10.1272/jnms.JNMS.2022_89-601

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  • Transileocolic endovascular treatment by a hybrid approach for severe acute portal vein thrombosis with bowel necrosis: Two case reports. International journal

    Sayaka Shirai, Tatsuo Ueda, Fumie Sugihara, Daisuke Yasui, Hidemasa Saito, Hiroyasu Furuki, Shiei Kim, Hiroshi Yoshida, Shoji Yokobori, Hiromitsu Hayashi, Shin-Ichiro Kumita

    World journal of clinical cases   10 ( 6 )   1876 - 1882   2022.2

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    BACKGROUND: Acute portal vein thrombosis (PVT) with bowel necrosis is a fatal condition with a 50%-75% mortality rate. This report describes the successful endovascular treatment (EVT) of two patients with severe PVT. CASE SUMMARY: The first patient was a 22-year-old man who presented with abdominal pain lasting 3 d. The second patient was a 48-year-old man who presented with acute abdominal pain. Following contrast-enhanced computed tomography, both patients were diagnosed with massive PVT extending to the splenic and superior mesenteric veins. Hybrid treatment (simultaneous necrotic bowel resection and EVT) was performed in a hybrid operating room (OR). EVTs, including aspiration thrombectomy, catheter-directed thrombolysis (CDT), and continuous CDT, were performed via the ileocolic vein under laparotomy. The portal veins were patent 4 and 6 mo posttreatment in the 22-year-old and 48-year-old patients, respectively. CONCLUSION: Hybrid necrotic bowel resection and transileocolic EVT performed in a hybrid OR is effective and safe.

    DOI: 10.12998/wjcc.v10.i6.1876

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  • Successful embolization of an intrahepatic portosystemic shunt using balloon-occluded retrograde transvenous obliteration: A case report. International journal

    Hidemasa Saito, Satoru Murata, Fumie Sugihara, Tatsuo Ueda, Daisuke Yasui, Izumi Miki, Hiromitsu Hayashi, Shin-Ichiro Kumita

    World journal of clinical cases   10 ( 6 )   2023 - 2029   2022.2

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    BACKGROUND: A congenital intrahepatic portosystemic shunt (IPSVS) is a rare vascular abnormality that is characterized by an anomalous intrahepatic venous tract that connects the intrahepatic portal vein with the hepatic venous system. Hepatic encephalopathy is an indication for IPSVS embolization, which is technically challenging because rapid blood flow through shunts can induce the migration of embolization material to systemic veins. This case report discusses the efficacy of percutaneous balloon-occluded retrograde transvenous obliteration for treating patients with IPSVSs. CASE SUMMARY: A 75-year-old woman presented with a six-month history of repeated hepatic encephalopathy due to an IPSVS without liver cirrhosis. We successfully embolized the IPSVS using percutaneous balloon-occluded retrograde transvenous obliteration with interlocking detachable coils. After the procedure, the patient exhibited no symptoms of hepatic encephalopathy for 14 mo. CONCLUSION: Balloon-occluded retrograde transvenous obliteration with detachable coils can be effective for the endovascular treatment of an IPSVS.

    DOI: 10.12998/wjcc.v10.i6.2023

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  • Endovascular treatment with Viabahn stent-grafts for arterial injury and bleeding at the visceral arteries: initial and midterm results.

    Tatsuo Ueda, Satoru Murata, Hiroyuki Tajima, Hidemasa Saito, Daisuke Yasui, Fumie Sugihara, Shohei Mizushima, Takahiko Mine, Hiroshi Kawamata, Hiromitsu Hayashi, Shin-Ichiro Kumita

    Japanese journal of radiology   40 ( 2 )   202 - 209   2022.2

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    PURPOSE: The purpose of the study is to evaluate the initial and midterm efficacy and safety of endovascular treatment (EVT) using Viabahn stent-graft (SG) for arterial injury and bleeding (AIB) at the visceral arteries. MATERIALS AND METHODS: Consecutive patients with visceral AIB who underwent EVT using Viabahn between January 2017 and February 2021 were retrospectively reviewed. Technical success, clinical success, peripheral organ ischemia, peri-procedural complications, bleeding-related mortality, 30-day mortality, neck length, re-bleeding, endoleaks, and patency of the SGs at 1, 3, 6, and 12 months were evaluated. RESULTS: EVT using Viabahn was performed in 14 patients (mean age: 68.6 years; 12 males) and 15 arteries. The technical and clinical success rates were 100%. The rates of peripheral organ ischemia, peri-procedural complications, bleeding-related mortality, and 30-day mortality were all 0%. The mean neck length was 9.9 mm. No endoleaks or re-bleeding occurred during the follow-up (mean: 732 days). The SG patency was confirmed after 1, 3, 6, and 12 months in 78.6%, 78.6%, 78.6%, and 56.1% of the patients, respectively. CONCLUSION: EVT using Viabahn for AIB at the visceral arteries was safe and effective. SG occlusions without ischemia often occurred after 12 months.

    DOI: 10.1007/s11604-021-01192-8

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  • Outcomes of abdominal aortic aneurysm repairs: Endovascular vs open surgical repairs. International journal

    Boonying Siribumrungwong, Jiro Kurita, Tatsuo Ueda, Daisuke Yasui, Ken-Ichiro Takahashi, Takashi Sasaki, Yasuo Miyagi, Shun-Ichiro Sakamoto, Yosuke Ishii, Tetsuro Morota, Takashi Nitta

    Asian journal of surgery   45 ( 1 )   346 - 352   2022.1

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    BACKGROUND: Operative mortality after endovascular aneurysm repair (EVAR) has been reported as lower than open surgical repair (OSR) for abdominal aortic aneurysm (AAA) in randomized controlled trials. However, many cohort studies have demonstrated similar mortality rates for both procedures. We compared operative mortality between EVAR and OSR, at our institution. METHODS: All AAA operations from 2012 to 2017 were reviewed, and baseline characteristics were collected. Outcomes included 30-day mortality, operative data, complications, length of hospital stay (LOS), costs, re-intervention, and survival rates were compared. A multivariable analysis with unbalanced characteristics was performed. RESULTS: We had a total of 162 patients, 100 having OSR and 62 for EVAR. The EVAR group was older, with higher ASA classification. Thirty-day mortality rate did not significantly differ (0/100 for OSR and 2/62 (3%) for EVAR; p = 0.145), while the EVAR group had less blood loss, shorter operative times, and LOS, but higher re-intervention rates (adjusted hazard ratio 6.4 (95%CI: 1.4, 26.8)). Survival rates did not significantly differ between the groups. EVAR cost approximately 1-million yen more. CONCLUSIONS: OSR had low 30-day mortality rate in selected low-risk patients whereas EVAR had less blood loss, shorter operative times, LOS and could be done in high-risk patients with low 30-day mortality but with higher re-intervention rate.

    DOI: 10.1016/j.asjsur.2021.06.015

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  • A Case of Chronic Mesenteric Ischemia: Complete Revascularization Using Multiple Procedures.

    Yusuke Yoshimura, Shun-Ichiro Sakamoto, Atushi Hiromoto, Tomohiro Murata, Kenji Suzuki, Daisuke Yasui, Satoshi Mizutani, Yosuke Ishii

    Annals of vascular diseases   14 ( 4 )   407 - 410   2021.12

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    Chronic mesenteric ischemia (CMI) involving occlusion and/or stenosis of multiple mesenteric arteries is rare. We report our experience with a 66-year-old man who presented with a more than 3 months history of abdominal pain and vomiting/diarrhea. A diagnosis of CMI due to occlusion of the superior mesenteric artery (SMA) and severe stenosis of the celiac artery by median arcuate ligament syndrome was made. Complete revascularization through iliac artery-SMA bypass grafting and arcuate ligament dissection assisted with staged-catheter intervention successfully alleviated the patient's symptoms. The patient has maintained a normal daily diet for 6 months postoperatively.

    DOI: 10.3400/avd.cr.21-00109

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  • Emergency endovascular treatment using a Viabahn stent graft for upper and lower extremity arterial bleeding: a retrospective study. International journal

    Tatsuo Ueda, Satoru Murata, Hiroyuki Tajima, Hidemasa Saito, Daisuke Yasui, Fumie Sugihara, Shohei Mizushima, Takahiko Mine, Hiroshi Kawamata, Hiromitsu Hayashi, Shin-Ichiro Kumita

    CVIR endovascular   4 ( 1 )   83 - 83   2021.12

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    BACKGROUND: A Viabahn stent graft (SG) is a heparin-coated self-expandable SG for lower extremity arterial disease that exhibits high flexibility and accuracy in the delivery system. This study aimed to evaluate the short-term efficacy and safety of emergency endovascular treatment (EVT) using a Viabahn SG for upper and lower extremity arterial bleeding (ULEAB). METHODS: Consecutive patients with ULEAB who underwent emergency EVT using the Viabahn SG between January 2017 and August 2021 were retrospectively reviewed. The indications for EVT, location of artery, technical success, clinical success, limb ischemia, periprocedural complications, bleeding-related mortality, 30-day mortality, diameter of the target artery, diameter of the SG, neck length, rebleeding, endoleaks, and patency of the SGs at 1, 3, 6, and 12 months were evaluated. RESULTS: EVT using the Viabahn SG was performed in 22 patients (mean age, 72.0 ± 13.0 years; 11 men) and 23 arteries (upper, 6; lower, 17). The indications for EVT were pseudoaneurysm (n = 13, 59.1%), extravasation (n = 9, 39.1%), and inadvertent arterial cannulation (n = 1, 4.3%). The anatomical locations of the 23 ULEAB injuries were the brachiocephalic (1 [4.3%]), subclavian (3 [13.0%]), axillary (1 [4.3%]), brachial (1 [4.3%]), common iliac (4 [17.4%]), external iliac (8 [34.8%]), common femoral (2 [8.7%]), superficial femoral (2 [8.7%]), and popliteal (1 [4.3%]) arteries. The technical and clinical success rates were 100%. The rates of limb ischemia, periprocedural complications, and bleeding-related mortality were 0%, whereas the 30-day mortality rate was 22.7%. The mean diameters of the arteries and SGs were 7.7 ± 2.2 and 8.9 ± 2.3 mm, respectively. The mean neck length was 20.4 ± 11.3 mm. No endoleaks or rebleeding occurred during the follow-up period (mean, 169 ± 177 days). Two SG occlusions without limb ischemia occurred in the external iliac and brachial arteries after 1 and 4 months, respectively. Subsequently, cumulative SG patency was confirmed after 1, 3, 6, and 12 months in 91.7%, 91.7%, 81.5%, and 81.5% of patients, respectively. CONCLUSIONS: Emergency EVT using the Viabahn SG for ULEAB was effective and safe according to short-term outcomes. Appropriate size selection and neck length are important for successful treatment. SG patency was good after 1, 3, 6, and 12 months.

    DOI: 10.1186/s42155-021-00273-z

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  • Effects of temperature alteration on viscosity, polymerization, and in-vivo arterial distribution of N-butyl cyanoacrylate-iodized oil mixtures.

    Takahiko Mine, Daisuke Yasui, Hidemasa Saito, Tatsuo Ueda, Taro Yokoyama, Shinpei Ikeda, Shohei Mizushima, Seigoh Happoh, Shin-Ichiro Kumita

    Japanese journal of radiology   39 ( 11 )   1111 - 1118   2021.11

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    PURPOSE: Temperature alteration can modify the polymerization of n-butyl cyanoacrylate (NBCA)-iodized oil mixtures during vascular embolization; its effects on viscosity, polymerization time, and intra-arterial distribution of the NBCA-iodized oil mixture were investigated. MATERIALS AND METHODS: In vitro, the viscosities of NBCA, iodized oil, and NBCA-iodized oil mixtures (ratio, 1:1-8) were measured at 4-60 ºC using a rotational rheometer. The polymerization times (from contact with blood plasma to stasis) were recorded at 0-60 ºC using a high-speed video camera. In vivo, the 1:2 mixture was injected into rabbit renal arteries at 0, 20, and 60 ºC; intra-arterial distribution of the mixture was pathologically evaluated. RESULTS: The mixtures' viscosities decreased as temperature increased; those at 60 ºC were almost four to five times lower than those at 4 ºC. The polymerization time of NBCA and the 1:1-4 mixtures increased as temperature decreased in the 0-30 ºC range; the degree of time prolongation increased as the percentage of iodized oil decreased. The 0 ºC group demonstrated distributions of the mixture within more peripheral arterial branches than the 20 and 60 ºC groups. CONCLUSION: Warming reduces the mixture's viscosity; cooling prolongs polymerization. Both can be potential factors to improve the handling of NBCA-iodized oil mixtures for lesions requiring peripheral delivery. Temperature alteration influences the polymerization time, viscosity, and intra-arterial distribution of NBCA-iodized oil mixtures. Warming reduces the viscosity of the mixture, while cooling prolongs polymerization.

    DOI: 10.1007/s11604-021-01143-3

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  • A Comparison of Outcomes Based on Vessel Type (Native Artery vs. Bypass Graft) and Artery Location (Below-Knee Artery vs. Non-Below-Knee Artery) Using a Combination of Multiple Endovascular Techniques for Acute Lower Limb Ischemia. International journal

    Tatsuo Ueda, Hiroyuki Tajima, Satoru Murata, Hidemasa Saito, Daisuke Yasui, Fumie Sugihara, Takahiko Mine, Izumi Miki, Jiro Kurita, Tetsuro Morota, Yosuke Ishii, Shoji Yokobori, Shin-Ichiro Kumita

    Annals of vascular surgery   75   205 - 216   2021.8

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    BACKGROUND: To evaluate outcomes of endovascular treatment (EVT) using a combination of multiple endovascular techniques for acute lower limb ischemia (ALLI) and to compare outcomes based on vessel type and artery location. METHODS: A total of 95 consecutive patients with ALLI (mean age, 72.0 years; 65 males; 104 lower limbs) who received emergency EVT using a combination of multiple endovascular techniques including thrombolysis, aspiration thrombectomy, stenting, and balloon angioplasty with or without surgical thromboembolectomy, between January 2005 and December 2017 were included. Vessel type was classified into native artery occlusion (native occlusion) and bypass graft occlusion (graft occlusion), including prosthetic and vein graft. Additionally, native arteries were categorized into below-knee occlusion and non-below-knee occlusion. Technical success, perioperative death (POD), ALLI-related death, amputation, amputation-free survival (AFS), and complications were compared according to vessel type (native occlusion vs. graft occlusion) and artery location (below-knee occlusion vs. non-below-knee occlusion). RESULTS: Of all patients with ALLI, 16.8% underwent a single endovascular technique, whereas 83.2% underwent a combination of multiple endovascular techniques. The technicalsuccess, POD, and ALLI-related death rates in the total number of patients were 94.7%, 11.6%, and 4.2%, respectively. A total of 67 patients (75 limbs) and 28 patients (29 limbs) were classified as having native occlusion and graft occlusion (prosthetic, 24 limbs; vein, 5 limbs), respectively. No significant differences in technical success (native occlusion: 92.5% vs. graft occlusion: 100%), POD (14.9% vs. 3.6%), and ALLI-related death (6.0% vs. 0%) were noted between native occlusion and graft occlusion. However, the 30-day AFS rate of native occlusion was significantly lower than that of graft occlusion (75.2% vs. 96.3%, P=0.01). The amputation rate (P=0.03) and AFS rate (P=0.03) of below-knee occlusion were significantly worse for below-knee occlusion patients than for non-below-knee occlusion patients. CONCLUSIONS: EVT using multiple endovascular techniques for ALLI is effective and safe. A combination of multiple endovascular techniques is crucial for successful treatment. However, native occlusion may have a lower AFS rate than graft occlusion, and below-knee occlusion may have a higher risk of amputation than non-below-knee occlusion.

    DOI: 10.1016/j.avsg.2021.02.023

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  • Successful Prophylactic Endovascular Therapy for a Rapidly Expanding Hepatic Arterial Aneurysm in a Patient with Vascular Ehlers-Danlos Syndrome.

    Yukihiro Watanabe, Koichi Akutsu, Daisuke Yasui, Fumie Sugihara, Hideki Miyachi, Hiroshi Hayashi, Eiichiro Oka, Hidenori Komiyama, Shin-Ichiro Kumita, Wataru Shimizu

    Annals of vascular diseases   14 ( 2 )   163 - 167   2021.6

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    Vascular Ehlers-Danlos syndrome (vEDS) causes fatal vascular complications due to vascular fragility. However, invasive therapeutic procedures are generally avoided except in emergencies. We report a case of vEDS presenting with rapid expansion of a hepatic arterial aneurysm successfully treated using prophylactic endovascular therapy. A 43-year-old woman with vEDS confirmed by genetic testing was hospitalized for a symptomatic hepatic arterial aneurysm that expanded rapidly within a week. Prophylactic coil embolization was then successfully performed. Although the general applicability of this approach cannot be determined, prophylactic endovascular therapy can clearly be an option for arterial aneurysms at high risk of rupture.

    DOI: 10.3400/avd.cr.20-00144

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  • A case of self-limiting sternal tumor of childhood. International journal

    Aya Yamane, Daisuke Yasui, Taro Ichikawa

    Radiology case reports   16 ( 3 )   602 - 603   2021.3

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    A 2-year-old boy with a rapidly growing sternal mass was referred to our hospital. Computed tomography revealed a dumbbell-shaped mass with widening of the synchondrosis between the third and fourth elements of the sternal body. The mass significantly shrunk 3 days later, and completely disappeared 2 weeks later, as confirmed by palpation. A diagnosis of self-limiting sternal tumor of childhood was made based on characteristic imaging findings.

    DOI: 10.1016/j.radcr.2020.12.052

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  • Novel treatment of vascular injury from delayed hemodialysis catheter migration by transvenous balloon-assisted embolization with n-butyl cyanoacrylate. International journal

    Ryutaro Fujitsuna, Fumie Sugihara, Daisuke Yasui, Hidemasa Saito, Tatsuo Ueda, Sayaka Shirai, Taiga Matsumoto, Yasuo Miyagi, Shin-Ichiro Kumita

    Radiology case reports   15 ( 9 )   1450 - 1454   2020.9

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    Delayed vascular injury (DVI) with a hemodialysis catheter is a rare but potentially life-threatening complication. However, the appropriate treatment for DVI has not yet been established. A 44-year-old man underwent placement of a hemodialysis catheter via the left internal jugular vein, and the first leukapheresis procedure was performed without complications. However, 3 days after the insertion of the hemodialysis catheter, the patient developed sudden dyspnea. Chest radiographs and contrast-enhanced computed tomography revealed that the catheter tip had migrated and was located outside the left brachiocephalic vein. DVI with catheter migration was diagnosed. To perform safe and reliable hemostasis, we successfully performed transvenous balloon-assisted tract embolization with n-butyl cyanoacrylate and the catheter was removed. To our knowledge, there has been no previous report of the treatment of balloon-assisted tract embolization with n-butyl cyanoacrylate for DVI caused by a hemodialysis catheter. Our treatment approach may be safe and effective for DVI.

    DOI: 10.1016/j.radcr.2020.05.077

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  • Balloon-assisted Transcatheter arterial embolization using N-butyl cyanoacrylate for iatrogenic arterial bleeding by groin puncture: a new technology. International journal

    Tatsuo Ueda, Satoru Murata, Hidemasa Saito, Izumi Miki, Daisuke Yasui, Fumie Sugihara, Wataru Shimizu, Shin-Ichiro Kumita

    CVIR endovascular   3 ( 1 )   42 - 42   2020.8

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    BACKGROUND: Balloon-assisted transcatheter arterial embolization (TAE) using n-butyl cyanoacrylate (NBCA) and lipiodol (Lp) mixture is a new endovascular treatment technique for iatrogenic arterial bleeding by groin puncture. It is less invasive compared to surgical repair, and NBCA migration into the circulation can be prevented by temporary balloon occlusion of the parent artery without ultrasound-guidance. This study aimed to report on the technical aspects and evaluate the efficacy and safety of fluoroscopically guided balloon-assisted transcatheter arterial embolization using NBCA for iatrogenic arterial bleeding by groin puncture. MATERIALS AND METHODS: The study included five patients (mean age 54.6 years; 3 male and 2 female) with iatrogenic arterial bleeding by groin puncture. We performed transcatheter arterial embolization using NBCA while occluding the responsible artery with a balloon catheter during the embolization to prevent NBCA migration. Two sheaths were inserted into the common femoral artery. A microcatheter was advanced into the pseudoaneurysm or extravasation via the contralateral sheath. A balloon catheter was advanced into the responsible artery until the balloon portion covered the leakage site via another sheath. After balloon inflation, the NBCA and Lip mixture was slowly injected until the pseudoaneurysm, or the extravasation was filled without touching the balloon. The microcatheter was removed immediately after the filling. We assessed technical success, overall success, and complications. RESULTS: The injured arteries were the external iliac artery (n = 1), the common femoral artery (n = 2), and the proximal portion of the superficial femoral artery (n = 2). NBCA was injected once in four cases and twice in one case where complete hemostasis could not be achieved with one injection. The technical and overall success rate was 100% with no complications, including distal embolization of NBCA. CONCLUSIONS: Balloon-assisted TAE using NBCA is a feasible, effective, and safe treatment for iatrogenic arterial bleeding by groin puncture. It may also be applicable in other arterial bleeding situations where the potential risk of distal embolization can be decreased by applying the balloon-assisted technique.

    DOI: 10.1186/s42155-020-00132-3

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  • Embolization using warmed glue via the triaxial microballoon occlusion system for various vascular disorders. International journal

    Takahiko Mine, Tatsuo Ueda, Daisuke Yasui, Shohei Mizushima, Shin-Ichiro Kumita

    Diagnostic and interventional radiology (Ankara, Turkey)   26 ( 3 )   241 - 244   2020.5

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    PURPOSE: We aimed to illustrate the benefits of using warmed glue for viscosity reduction via the triaxial microballoon system for the treatment of various vascular disorders. METHODS: Seven patients who underwent 10 treatment sessions for hemoptysis, type II endoleak, post-pancreatic surgical bleeding, spontaneous retroperitoneal bleeding, or ovarian tumor bleeding were evaluated based on technical and clinical outcomes. In the procedure, the triaxial system, consisting of a 4.5-Fr guiding catheter, a 2.8-Fr microballoon catheter, and a 1.9-Fr no-taper microcatheter, was advanced into the target lesion. Glue (33% n-butyl cyanoacrylate mixed with Lipiodol) warmed to 40°C was injected under balloon occlusion. RESULTS: The common hepatic, right bronchial, intercostals, internal mammary, costocervical, lateral thoracic, superior thoracic, thoracoacromial, inferior thyroid, iliolumbar, lumbar, internal pudendal arteries, and branch of the inferior mesenteric artery were successfully embolized; 100% technical success and 100% clinical success were obtained after each session. CONCLUSION: Our modified balloon-occluded glue embolization may lead to better handling with more distal glue penetration capability.

    DOI: 10.5152/dir.2019.19285

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  • Long-term outcomes of endovascular aortic aneurysm repair with the Zenith AAA endovascular graft: a single-center study.

    Hiroshi Kawamata, Hiroyuki Tajima, Tatsuo Ueda, Hidemasa Saito, Daisuke Yasui, Tadashi Kaneshiro, Naoko Takenoshita, Shouhei Mizushima, Takahiko Mine, Jiro Kurita, Yosuke Ishii, Tetsuro Morota, Takashi Nitta, Yuji Maruyama, Hajime Imura, Dai Nishina, Masahiro Fujii, Ryuzo Bessho

    Japanese journal of radiology   38 ( 1 )   77 - 84   2020.1

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    PURPOSE: To present long-term results obtained with endovascular abdominal aortic aneurysm (AAA) repair (EVAR) using the Zenith AAA endovascular graft from a single institution. MATERIALS AND METHODS: Between 2007 and 2013, 95 consecutive patients (median age 77 years) underwent EVAR using Zenith. Data were prospectively collected and retrospectively analyzed until 2019. Primary outcomes were overall survival, freedom from AAA rupture, and freedom from AAA-related death. Secondary outcomes were freedom from late (> 30 days) re-intervention and surgical conversion, and freedom from aneurysm sac growth (> 5 mm). RESULTS: The initial technical success rate was 96.8%. There were no deaths or intraoperative conversions. Overall survival at 1, 3, 5, and 10 years was 90.8%, 81.7%. 74.3%, and 57.2%, respectively. AAA rupture occurred in one patient (1.1%). Freedom from AAA-related death was 100% during the follow-up period. Freedom from aneurysm sac growth at 1, 3, 5, and 10 years was 98.8%, 86.4%, 76.9%, 53.0%, respectively. Freedom from late re-intervention and open surgical conversion at 1, 3, 5, and 10 years was 98.9%, 88.9%, 86.7, and 57.9%, respectively. CONCLUSION: EVAR with Zenith endografts represents a safe and durable means of AAA repair, and risk of rupture and aneurysm-related death are low.

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  • In vivo evaluation of a monodisperse solid-in-oil-in-water miriplatin/ lipiodol emulsion in transcatheter arterial chemoembolization using a rabbit VX2 tumor model. International journal

    Daisuke Yasui, Aya Yamane, Hiroshi Itoh, Masayuki Kobayashi, Shin-Ichiro Kumita

    PloS one   15 ( 8 )   e0222553   2020

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    Transcatheter arterial chemoembolization (TACE) is a standard treatment for unresectable hepatocellular carcinoma; however, it does not always result in tumor control. Nevertheless, treatment outcome can be improved with monodisperse emulsions of anticancer agents. In this study, the distribution of a monodisperse miriplatin-Lipiodol emulsion in the tumor and its safety were evaluated in ten Japanese white rabbits. VX2 tumor was implanted into the left liver lobe. The animals were divided into control and experimental groups (of five animals each) and respectively administered a conventional miriplatin suspension or the emulsion via the left hepatic artery. Computed tomography (CT) was performed before, immediately after, and two days following TACE. All rabbits were sacrificed two days after the procedure. Each tumor was removed and cut in half for assessment of iodine concentration in one half by mass spectroscopy and evaluation of Lipiodol accumulation and adverse events in the other half. Mean Hounsfield unit (HU) values were measured using plain CT images taken before and after TACE. Iodine concentration was higher in the experimental group [1100 (750-1500) ppm, median (range)] than in the control group [840 (660-1800) ppm], although statistically not significant. Additionally, the HU value for the experimental group was higher than that for the control group immediately after [199.6 (134.0-301.7) vs. 165.3 (131.4-280.5)] and two days after [114.2 (56.1-229.8) vs. 58.3 (42.9-132.5)] TACE, although statistically not significant. Cholecystitis was observed in one rabbit in the control group. Ischemic bile duct injury was not observed in any group. The results show that Lipiodol accumulation and retention in VX2 tumor can possibly be improved with a monodisperse emulsion; however, it should be verified with a larger study. Moreover, no significant adverse events are associated with the use of the emulsion.

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  • An Extremely Rare Complication: Abdominal Aortic Aneurysm Rupture Caused by Migration of a Zenith Main Body Years After Repair of the Suprarenal Stent Separation. International journal

    Tatsuo Ueda, Hiroyuki Tajima, Satoru Murata, Kotomi Iwata, Hidemasa Saitou, Izumi Miki, Daisuke Yasui, Fumie Sugihara, Shiro Onozawa, Tetsuro Morota, Shin-Ichiro Kumita

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists   26 ( 2 )   269 - 272   2019.4

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    PURPOSE: To report an unusual case of an abdominal aortic aneurysm (AAA) rupture caused by migration of a Zenith stent-graft main body years after its separation from the suprarenal stent. CASE REPORT: A 72-year-old man underwent endovascular aneurysm repair with a Zenith stent-graft for an infrarenal AAA in year 2000. At that time, a femorofemoral bypass was performed because the left external iliac and common femoral arteries were dissected during treatment. In 2013, follow-up computed tomography (CT) showed disconnection of the uncovered proximal stent, which led to a type Ia endoleak. An additional Zenith main body and Large Palmaz XL balloon-expandable stent were deployed; the endoleak disappeared. In 2016, the patient had abdominal pain, and emergency CT showed AAA rupture caused by migration of the first main body deployed in 2000 under the distal edge of the contralateral (left) leg of the additional main body from 2013, which led to a type IIIa endoleak between the 2 main bodies. A converter and iliac legs were deployed to successfully seal the type IIIa endoleak. The patient remains well 18 months after the second repair; CT scans document stable stent-grafts and no endoleak. CONCLUSION: Physicians should be aware of the potential risk for AAA rupture caused by late main body migration after treatment for suprarenal stent separation from a Zenith stent-graft.

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  • Evaluating the Feasibility of Isolated Pancreatic Perfusion for Chemotherapy Using Computed Tomography: An Experimental Study in Pig Models. International journal

    Satoru Murata, Shiro Onozawa, Daisuke Yasui, Tatsuo Ueda, Fumie Sugihara, Akira Shimizu, Kenichi Suzuki, Mitsuo Satake

    Cardiovascular and interventional radiology   41 ( 7 )   1081 - 1088   2018.7

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    PURPOSE: Percutaneous isolated pancreatic perfusion (PIPP) is performed along with interventional radiology techniques to obtain high drug concentration by occluding the arterial inlet and venous outlet of the pancreas. The experimental study aimed to evaluate the contrast distribution in PIPP under different flow rates with or without anterior mesenteric artery (AMA) occlusion. MATERIALS AND METHODS: This study was approved by a local animal experiment ethics committee. Nine pigs were divided into Groups 1, 2, and 3, by infusion rates of 12, 24, and 36 mL/min. Groups 4 and 5 (3 pigs each) and Group 6 (2 pigs) underwent PIPP at the same respective infusion rates with and without AMA occlusion. Computed tomography (CT) arteriography was performed during PIPP with nonionic contrast media. The enhanced volume was calculated by adding the enhanced area in each slice using 1.25-mm axial images. The percent enhanced volume to the whole pancreas (%eV) was used to simulate drug distribution; the result was compared among groups. RESULTS: Without AMA occlusion, a larger %eV was obtained with high infusion rates (P = 0.039). The median %eV in Groups 1, 2, and 3 were 57.7, 74.2, and 90.5%, respectively. With AMA occlusion, CT demonstrated duodenal enhancement at an infusion rate of 36 mL/min, and the median %eV in Groups 4, 5, and 6 were 92.8, 95.4, and 98.5%, respectively. A significantly larger %eV was obtained after AMA occlusion (P = 0.031). CONCLUSION: A higher infusion rate or AMA occlusion increases the enhanced volume in PIPP in pig models. LEVEL OF EVIDENCE: No level of evidence.

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  • Novel treatment strategy for advanced hepatocellular carcinoma: combination of conventional transcatheter arterial chemoembolization and modified method with portal vein occlusion for cases with arterioportal shunt: a preliminary study. International journal

    Daisuke Yasui, Satoru Murata, Tatsuo Ueda, Fumie Sugihara, Shiro Onozawa, Chiaki Kawamoto, Shinichiro Kumita

    Acta radiologica (Stockholm, Sweden : 1987)   59 ( 3 )   266 - 274   2018.3

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    Background A novel strategy to combine conventional transcatheter arterial chemoembolization (TACE) and TACE during portal vein occlusion (TACE-PVO) in the presence of high-flow arterioportal shunt (APS) has been developed to treat hepatocellular carcinoma (HCC) with portal invasion. Purpose To evaluate the efficacy of this strategy. Material and Methods Twenty-five cases of HCC with portal invasion, treated between April 2006 and December 2015, were evaluated. Balloon occlusion of the portal venous outlet was performed in eight cases of high-flow APS when performing TACE. Conventional TACE was performed in the other 17 cases. The primary endpoint was overall survival. Adverse events and deterioration of liver function were also evaluated. Results The median survival time (MST) was 12 months. One-, two-, and three-year survival rates were 48.0%, 39.3%, and 26.2%, respectively. Subgroup analysis and multivariate analysis revealed the CLIP score as prognostic factor. MST was 2.5 months in the subgroup with CLIP score ≥4 and 26.0 months in the subgroup with CLIP score ≤3 (hazard ratio = 7.7, 95% confidence interval = 2.3-25.8). Transient elevations of the levels of transaminase and bilirubin were observed; however, deterioration of liver function was infrequent; upgrading of Child-Pugh class in 9.1% of cases. Conclusion A novel strategy, combining conventional TACE and TACE-PVO, is effective for HCC with portal invasion. The CLIP score may be useful for considering treatment indication.

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  • Evaluation of the relationship between hepatocellular carcinoma location and transarterial chemoembolization efficacy. International journal

    Izumi Miki, Satoru Murata, Fumio Uchiyama, Daisuke Yasui, Tatsuo Ueda, Fumie Sugihara, Hidemasa Saito, Hidenori Yamaguchi, Ryusuke Murakami, Chiaki Kawamoto, Eiji Uchida, Shin-Ichiro Kumita

    World journal of gastroenterology   23 ( 35 )   6437 - 6447   2017.9

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    AIM: To evaluate the relationship between the location of hepatocellular carcinoma (HCC) and the efficacy of transarterial chemoembolization (TACE). METHODS: We evaluated 115 patients (127 nodules), excluding recurrent nodules, treated with TACE between January 2011 and June 2014. TACE efficacy was evaluated according to mRECIST. The HCC location coefficient was calculated as the distance from the central portal portion to the HCC center (mm)/liver diameter (mm) on multiplanar reconstruction images rendered (MPR) to visualize bifurcation of the right and left branches of the portal vein and HCC center. The HCC location coefficient was compared between complete response (CR) and non-CR groups in Child-Pugh grade A and B patients. RESULTS: The median location coefficient of HCC among all nodules, the right lobe, and the medial segment was significantly higher in the CR group than in the non-CR group in the Child-Pugh grade A patients (0.82 vs 0.62, P < 0.001; 0.71 vs 0.59, P < 0.01; 0.81 vs 0.49, P < 0.05, respectively). However, there was no significant difference in the median location coefficient of the HCC in the lateral segment between in the CR and in the non-CR groups (0.67 vs 0.65, P > 0.05). On the other hand, in the Child-Pugh grade B patients, the HCC median location coefficient in each lobe and segment was not significantly different between in the CR and in the non-CR groups. CONCLUSION: Improved TACE efficacy may be obtained for HCC in the peripheral zone of the right lobe and the medial segment in Child-Pugh grade A patients.

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  • Endovascular Treatment Strategy Using Catheter-Directed Thrombolysis, Percutaneous Aspiration Thromboembolectomy, and Angioplasty for Acute Upper Limb Ischemia. International journal

    Tatsuo Ueda, Satoru Murata, Izumi Miki, Daisuke Yasui, Fumie Sugihara, Hiroyuki Tajima, Tetsuro Morota, Shin-Ichiro Kumita

    Cardiovascular and interventional radiology   40 ( 7 )   978 - 986   2017.7

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    PURPOSE: To evaluate the usefulness and safety of endovascular treatments for acute upper limb ischemia (AULI) by using multiple techniques, and to compare catheter-directed thrombolysis (CDT) and percutaneous aspiration thromboembolectomy (PAT) as initial procedures. MATERIALS AND METHODS: The study included 18 patients (4 men and 14 women) with AULI, who underwent a total of 20 sessions of endovascular treatment using various endovascular techniques between January 2005 and April 2016. The patients were initially treated with CDT [n = 9, CDT-based group (C-G)], PAT [n = 6, PAT-based group (P-G)], or angioplasty (n = 3). In case of residual emboli, we performed additional endovascular techniques. We assessed technical success, clinical success, and complications. Additionally, we compared the urokinase dosage between the groups. RESULTS: The mean patient age was 74.4 years. Technical and clinical success was obtained in all patients. Among the 18 patients, 1 underwent CDT only, 2 underwent PAT only, 1 underwent angioplasty only, and 14 underwent multiple techniques. Two patients from the C-G experienced major complications (cerebellar hemorrhage 1; pseudo-aneurysm in a branch of the ulnar artery 1). The mean urokinase dosage was lower in the P-G than in the C-G (40,000 vs. 246,667 IU; Mann-Whitney U test, P = 0.004). CONCLUSION: Endovascular treatment is effective and safe for AULI. A combination of multiple endovascular techniques is important for successful treatment. PAT is suggested as an initial procedure among endovascular techniques, in terms of a lower dosage of urokinase and a lower complication rate. LEVEL OF EVIDENCE: IV, Case-control studies.

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  • Haemodynamic changes in hepatocellular carcinoma and liver parenchyma under balloon occlusion of the hepatic artery. International journal

    Fumie Sugihara, Satoru Murata, Tatsuo Ueda, Daisuke Yasui, Hidenori Yamaguchi, Izumi Miki, Chiaki Kawamoto, Eiji Uchida, Shin-Ichiro Kumita

    European radiology   27 ( 6 )   2474 - 2481   2017.6

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    OBJECTIVES: To investigate haemodynamic changes in hepatocellular carcinoma (HCC) and liver under hepatic artery occlusion. METHODS: Thirty-eight HCC nodules in 25 patients were included. Computed tomography (CT) during hepatic arteriography (CTHA) with and without balloon occlusion of the hepatic artery was performed. CT attenuation and enhancement volume of HCC and liver with and without balloon occlusion were measured on CTHA. Influence of balloon position (segmental or subsegmental branch) was evaluated based on differences in HCC-to-liver attenuation ratio (H/L ratio) and enhancement volume of HCC and liver. RESULTS: In the segmental group (n = 20), H/L ratio and enhancement volume of HCC and liver were significantly lower with balloon occlusion than without balloon occlusion. However, in the subsegmental group (n = 18), H/L ratio was significantly higher and liver enhancement volume was significantly lower with balloon occlusion; HCC enhancement volume was similar with and without balloon occlusion. Rate of change in H/L ratio and enhancement volume of HCC and liver were lower in the segmental group than in the subsegmental group. There were significantly more perfusion defects in HCC in the segmental group. CONCLUSIONS: Hepatic artery occlusion causes haemodynamic changes in HCC and liver, especially with segmental occlusion. KEY POINTS: • Hepatic artery occlusion causes haemodynamic changes in hepatocellular carcinoma and liver. • Segmental occlusion decreased rate of change in hepatocellular carcinoma-to-liver attenuation ratio. • Subsegmental occlusion increased rate of change in hepatocellular carcinoma-to-liver attenuation ratio. • Hepatic artery occlusion decreased enhancement volume of hepatocellular carcinoma and liver. • Hepatic artery occlusion causes perfusion defects in hepatocellular carcinoma.

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  • Diaphragm height varies with arm position: comparison between angiography and CT.

    Shiro Onozawa, Satoru Murata, Takayoshi Kimura, Tatsuo Ueda, Fumie Sugihara, Daisuke Yasui, Hiroyuki Tajima

    Japanese journal of radiology   34 ( 11 )   724 - 729   2016.11

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    PURPOSE: To investigate how elevation of the arms affects diaphragm height. MATERIALS AND METHODS: We retrospectively reviewed angiography and computed tomography (CT) portography data from 44 patients who were treated for hepatocellular carcinoma at our institution from July 2013 to May 2014. Diaphragm height was determined independently by two radiologists as the distance from the upper edge of the first lumbar vertebra to the highest point of the right diaphragm. The differences in height between angiography and CT images were compared using a paired t-test. We also evaluated the influence of table height and distance between X-ray tube and flat panel detector [source-image distance (SID)] on a phantom model. RESULTS: Diaphragm height was higher on CT images [mean ± standard deviation (SD), 113.2 ± 27.2 mm] than on angiography images (105.5 ± 27.8 mm; P < 0.001). Inter-rater correlation was excellent both in angiography (R = 0.920; P < 0.001) and CT (R = 0.950; P < 0.001) measurements. Table height and SID had no influence on diaphragm height measurements (P = 0.33). CONCLUSION: The diaphragm elevation was observed on CT with arm elevation compared with angiography without arm elevation.

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  • Combination Therapy of Interventional Radiology and Surgery for Infarction of the Small Intestine Caused by Portal Vein and Mesenteric Vein Thrombosis: A Patient Report.

    Takayoshi Kimura, Satoru Murata, Shiro Onozawa, Takahiko Mine, Tatsuo Ueda, Fumie Sugihara, Daisuke Yasui, Izumi Miki, Shinichiro Kumita, Toshihide Ogawa

    Yonago acta medica   59 ( 3 )   237 - 240   2016.9

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    We report the case of a man in his 70s who suffered from intestinal infarction caused by acute portal vein and mesenteric vein thrombosis (PVMVT). Combination therapy with percutaneous transcatheter thrombectomy and surgical bowel resection was successfully performed, and a satisfactory outcome was achieved. Intestinal infarction caused by PVMVT can be fatal and has a high mortality rate even if surgical resection is performed. The combination therapy of interventional radiology and surgery might be a safe and effective method for patients with this life-threatening condition.

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  • Can an enhanced thin-slice computed tomography delineate the right adrenal vein and improve the success rate?

    Shiro Onozawa, Satoru Murata, Hidenori Yamaguchi, Takahiko Mine, Daisuke Yasui, Hitoshi Sugihara, Hiroyuki Tajima

    Japanese journal of radiology   34 ( 9 )   611 - 9   2016.9

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    PURPOSE: To evaluate the usefulness of enhanced thin-slice computed tomography (TSCT) for delineating the right adrenal vein (RAV) anatomy before adrenal vein sampling (AVS). MATERIALS AND METHODS: A total of 151 consecutive AVSs with CT during angiography (interventional CT) were included. Of them, TSCT was performed before AVS for 72 patients. Successful RAV cannulation was confirmed using cortisol measurement. The RAV on TSCT was classified as certain, probable, or unidentified, and cases with certain or probable RAV identification were classified as useful. In the cases where AVS was successful, the anatomical features of the presumed RAV from the useful TSCT, including the position along the inferior vena cava, vertebral level, and distance from the upper pole of the right kidney, were compared with the RAV features identified on interventional CT. Estimated successful cannulation rates before interventional CT were compared between patients with and without useful TSCT. RESULTS: In total, 66 TSCTs were classified as useful. The anatomical features identified on TSCT were significantly correlated with those on interventional CT. The estimated successful cannulation rates for cases with and without useful TSCT were 92.4 and 82.4 %, respectively. CONCLUSIONS: TSCT clearly shows the anatomical features of the RAV, facilitating accurate sampling and increasing the success rate.

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  • Amplatzer Vascular Plug Anchoring Technique to Stabilize the Delivery System for Microcoil Embolization. International journal

    Shiro Onozawa, Satoru Murata, Takahiko Mine, Fumie Sugihara, Daisuke Yasui, Shin-Ichiro Kumita

    Cardiovascular and interventional radiology   39 ( 5 )   756 - 760   2016.5

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    PURPOSE: To evaluate the feasibility of a novel embolization technique, the Amplatzer vascular plug (AVP) anchoring technique, to stabilize the delivery system for microcoil embolization. MATERIALS AND METHODS: Three patients were enrolled in this study, including two cases of internal iliac artery aneurysms and one case of internal iliac arterial occlusion prior to endovascular aortic repair. An AVP was used in each case for embolization of one target artery, and the AVP was left in place. The AVP detachment wire was then used as an anchor to stabilize the delivery system for microcoil embolization to embolize the second target artery adjacent to the first target artery. The microcatheter for the microcoils was inserted parallel to the AVP detachment wire in the guiding sheath or catheter used for the AVP. RESULTS: The AVP anchoring technique was achieved and the microcatheter was easily advanced to the second target artery in all three cases. CONCLUSION: The AVP anchoring technique was found to be feasible to advance the microcatheter into the neighboring artery of an AVP-embolized artery.

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  • Glue Embolization of a Blunt Traumatic Hepatic Arteriovenous Fistula under Inflow and Outflow Control.

    Takahiko Mine, Satoru Murata, Daisuke Yasui, Hiroyuki Yokota, Hiroyuki Tajima, Shin-ichiro Kumita

    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   83 ( 1 )   27 - 30   2016

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    We report on a rare case of blunt traumatic hepatic arteriovenous fistula arising from a pseudoaneurysm in a 35-year-old woman. Transarterial embolization was performed with n-butyl-2-cyanoacrylate, under inflow control with loose coil packing within the pseudoaneurysm and outflow control by balloon occlusion of the hepatic vein. A promising therapeutic outcome was achieved without any serious adverse events. Thus, the combination of these techniques to control inflow and outflow was successfully used to treat this rare hepatic vascular injury.

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  • Feasibility and Safety of Negative-Balance Isolated Pelvic Perfusion in Patients with Pretreated Recurrent or Persistent Uterine Cervical Cancer. International journal

    Satoru Murata, Shiro Onozawa, Fumie Sugihara, Atsuhiro Sakamoto, Tatsuo Ueda, Hidenori Yamaguchi, Daisuke Yasui, Takahiko Mine, Shinichiro Kumita

    Annals of surgical oncology   22 ( 12 )   3981 - 9   2015.11

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    BACKGROUND: Second-line therapy has limited activity in patients with recurrent or persistent uterine cervical cancer that has progressed after chemoradiation and palliative chemotherapy. The purpose of this study was to evaluate the efficacy of negative-balance isolated pelvic perfusion (NIPP) in patients with pretreated recurrent/persistent uterine cervical cancer. METHODS: Between April 2004 and May 2013, a total of 26 patients with recurrent or persistent uterine cervical cancer previously treated with platinum-based systemic chemotherapy and/or chemoradiotherapy received NIPP therapy at our institution, consisting of a 30-min isolated pelvic perfusion with cisplatin and fluorouracil, followed by isolated pelvic dialysis. Primary endpoints were response rate (RR) and progression-free survival (PFS), while secondary endpoints were overall survival (OS) and safety. Platinum pharmacokinetics were also evaluated. RESULTS: The RR was 57.7 % (complete response, five patients; partial response, ten patients). The median PFS and OS after NIPP therapy were 11.0 (95 % confidence interval [CI] 6.6-15.4) and 25.1 (95 % CI 17.1-33.1) months, respectively. PFS was significantly better in patients without intestinal involvement (p = 0.016) or dissemination (p < 0.001). Survival rates at 1, 2, and 3 years after initial NIPP therapy were 65.2, 50.4, and 13.4 %, respectively. The plasma pelvic-to-systemic exposure ratios were 15.4 and 15.8, based on the maximum concentration and the concentration-time curve, respectively. Most adverse events were mild (grade 1-2) (Common Terminology Criteria for Adverse Events, version 3.0). Severe neutropenia (grade 3 or higher) occurred in only 7.7 % of patients. CONCLUSIONS: NIPP appears to be an effective and feasible method for patients with pretreated recurrent or persistent cervical cancer.

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  • Minimizing Systemic Leakage of Cisplatin during Percutaneous Isolated Pancreas Perfusion Chemotherapy: A Pilot Study. International journal

    Satoru Murata, Shiro Onozawa, Takahiko Mine, Tatsuo Ueda, Fumie Sugihara, Daisuke Yasui, Shin-ichiro Kumita, Akira Shimizu, Mitsuo Satake

    Radiology   276 ( 1 )   102 - 9   2015.7

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    PURPOSE: To evaluate the feasibility of percutaneous isolated pancreas perfusion (PIPP) by using a pig model. MATERIALS AND METHODS: All experiments were approved by the institutional Animal Experiment Ethics Committee. Fifteen pigs were assigned to five groups, and PIPP was performed. Angiographic and dye injection studies were performed to confirm the patency of the PIPP system (group 1). Blood that contained cisplatin (1.5 mg per kilogram of body weight) in an extracorporeal circuit was circulated through the pancreas at three infusion rates (40, 60, and 80 mL/min) to determine the optimal infusion rate in terms of safety and pharmacologic effectiveness (groups 2, 3, and 4, respectively). Chronological laboratory data and histologic findings were assessed in group 5, which received the optimal infusion rate. Maximum platinum concentration (Cmax) and area under the platinum concentration-time curve were compared by using the Kruskal-Wallis and Mann-Whitney U tests. RESULTS: Angiography and dye injection confirmed the patency of the PIPP system. Histopathologic examinations showed no abnormalities in the pancreas or other organs at a 40 mL/min infusion rate of cisplatin. However, edematous changes in the pancreas were observed at higher infusion rates. The pharmacologic effectiveness did not differ significantly among groups; therefore, the optimal infusion rate of 40 mL/min was selected. The median pancreatic-to-systemic exposure ratios were 71.8 for Cmax and 54.8 for the area under the curve. All laboratory data remained normal or returned to pretreatment levels within 1 week. CONCLUSION: PIPP at a 40 mL/min infusion rate appears to be safe and feasible for perfusion of the pancreas.

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  • Retrograde-outflow percutaneous isolated hepatic perfusion using cisplatin: A pilot study on pharmacokinetics and feasibility. International journal

    Satoru Murata, Shiro Onozawa, Takahiko Mine, Tatsuo Ueda, Fumie Sugihara, Daisuke Yasui, Shin-Ichiro Kumita, Mitsuo Satake

    European radiology   25 ( 6 )   1631 - 8   2015.6

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    OBJECTIVES: This study aimed to evaluate the feasibility and underlying pharmacokinetics of the retrograde-outflow technique for percutaneous isolated hepatic perfusion (PIHP). METHODS: Retrograde-outflow PIHP was performed in 12 male pigs (weight, 37-44 kg) by redirecting hepatic outflow through the portal vein. Blood with cisplatin (2.5 mg/kg) in an extracorporeal circuit was circulated through the liver under isolation using rotary pumps with balloon catheters. Hepatic angiographic examinations were conducted during perfusion, and histopathological examinations of the organs were conducted after perfusion. The maximum platinum concentration (C max), area under the concentration-time curve (AUC), and chronologic laboratory data were measured. RESULTS: Retrograde-outflow isolated hepatic angiography confirmed that contrast media flowed into the portal veins in all 12 pigs. The hepatic veins and inferior vena cava were not opacified. Hepatic C max (86.3 mg/l) was 39-fold greater than systemic C max (2.2 mg/l), and hepatic AUC (1330.8 min · mg/l) was 30-fold greater than systemic AUC (44.6 min · mg/l). Histopathological examinations revealed no ischaemic changes or other abnormalities in the liver, duodenum, small intestine, or colon. Within 1 week of the procedure, chronologic laboratory data (n = 3) normalized or returned to pre-therapy levels. CONCLUSIONS: The retrograde-outflow technique appears to enable safe and feasible PIHP therapy. KEY POINTS: • The portal vein acted as an outflow tract under retrograde-outflow PIHP. • Plasma hepatic-to-systemic exposure ratio was 39.2 for the maximum platinum concentration. • Plasma hepatic-to-systemic exposure ratio was 29.8 for the AUC. • The retrograde-outflow technique appears to enable safe and feasible PIHP.

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  • Interventional treatment for unresectable hepatocellular carcinoma. International journal

    Satoru Murata, Takahiko Mine, Fumie Sugihara, Daisuke Yasui, Hidenori Yamaguchi, Tatsuo Ueda, Shiro Onozawa, Shin-ichiro Kumita

    World journal of gastroenterology   20 ( 37 )   13453 - 65   2014.10

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    Hepatocellular carcinoma (HCC) is the sixth most common cancer and third leading cause of cancer-related death in the world. The Barcelona clinic liver cancer classification is the current standard classification system for the clinical management of patients with HCC and suggests that patients with intermediate-stage HCC benefit from transcatheter arterial chemoembolization (TACE). Interventional treatments such as TACE, balloon-occluded TACE, drug-eluting bead embolization, radioembolization, and combined therapies including TACE and radiofrequency ablation, continue to evolve, resulting in improved patient prognosis. However, patients with advanced-stage HCC typically receive only chemotherapy with sorafenib, a multi-kinase inhibitor, or palliative and conservative therapy. Most patients receive palliative or conservative therapy only, and approximately 50% of patients with HCC are candidates for systemic therapy. However, these patients require therapy that is more effective than sorafenib or conservative treatment. Several researchers try to perform more effective therapies, such as combined therapies (TACE with radiotherapy and sorafenib with TACE), modified TACE for HCC with arterioportal or arteriohepatic vein shunts, TACE based on hepatic hemodynamics, and isolated hepatic perfusion. This review summarizes the published data and data on important ongoing studies concerning interventional treatments for unresectable HCC and discusses the technical improvements in these interventions, particularly for advanced-stage HCC.

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  • Anatomical relationship between the common carotid artery and the internal jugular vein during head rotation. International journal

    Izumi Miki, Satoru Murata, Ken Nakazawa, Shiro Onozawa, Takahiko Mine, Tatsuo Ueda, Hidenori Yamaguchi, Daisuke Yasui, Minako Takeda, Shinichiro Kumita

    Ultrasound (Leeds, England)   22 ( 2 )   99 - 103   2014.5

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    This study investigated the anatomical relationship between the common carotid artery and internal jugular vein during head rotation for the effective performance of percutaneous transjugular procedures. The subjects included 30 volunteers who had never undergone internal jugular vein cannulation. In the supine position, two-dimensional ultrasonographic images of the right internal jugular vein and common carotid artery were obtained, 2 and 4 cm above the clavicle, along the lateral border of the sternal head of the sternocleidomastoid muscle. Ultrasonographic images were examined for head rotation at 0°, 15°, 30°, 45°, 60°, and 75° from the midline to the left. The percentage of overlap of the common carotid artery by the internal jugular vein and the flattening of the internal jugular vein at each head rotation position were measured and evaluated. The overlap of the common carotid artery by the internal jugular vein significantly increased at ≥45° of head rotation 2 cm above the clavicle (P < 0.01) and at ≥30° of head rotation 4 cm above the clavicle (P < 0.01), compared with that observed in the neutral position. The flattening of the internal jugular vein significantly decreased at ≥45° of head rotation 2 cm above the clavicle (P < 0.01) and at ≥30° of head rotation 4 cm above the clavicle (P < 0.01). Head rotation should be kept to <45° at 2 cm above the clavicle and <30° at 4 cm above the clavicle to decrease the risk of accidental puncture of the common carotid artery during internal jugular vein puncture. Moreover, flattening of the internal jugular vein gradually decreases during head rotation to the side.

    DOI: 10.1177/1742271X14524571

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  • Endovascular embolization strategy for renal arteriovenous malformations. International journal

    Satoru Murata, Shiro Onozawa, Ken Nakazawa, Ayako Akiba, Takahiko Mine, Tatsuo Ueda, Daisuke Yasui, Fumie Sugihara, Yukihiro Kondoh, Shin-ichiro Kumita

    Acta radiologica (Stockholm, Sweden : 1987)   55 ( 1 )   71 - 7   2014.2

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    BACKGROUND: Renal arteriovenous malformations (AVMs) are rare vascular malformations that cause hematuria. Treatment for renal AVMs has evolved from open nephrectomy to transcatheter arterial embolization (TAE). PURPOSE: To retrospectively evaluate efficacy and adverse events of TAE for renal AVMs. MATERIAL AND METHODS: We examined 12 patients (three men, nine women; mean age, 56 years) with renal AVM with gross hematuria, who underwent 14 sessions of treatment, using various embolization materials (liquid embolization agents, gelatin sponge, and coils). Among the 12 patients, 10 had cirsoid AVMs, eight of which were high-flow lesions. The remaining two patients had aneurismal AVMs. We assessed technical and clinical success, and also complications. All patients were followed for 7-92 months (mean, 48 months). RESULTS: Technical success was obtained in all patients. Primary clinical success was obtained in all patients; however, recurrence was observed in two patients who were treated with coils alone. A second session of TAE led to the sustained relief of symptoms. Clinical success rate was significant better (P = 0.045) when coils combined with other agents or liquid agents were used, than when only coils were used. No major complications occurred in any of patients; post-embolization syndrome and deterioration of renal function were not observed. CONCLUSION: TAE treatment was safe, effective, and provided a good outcome, except when only coils were used as the embolization agent.

    DOI: 10.1177/0284185113493085

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  • Endovascular recanalization techniques for popliteal arterial occlusive injury with limb-threatening ischemia secondary to trauma. International journal

    Takahiko Mine, Satoru Murata, Daisuke Yasui, Hiroyuki Tajima, Hiroshi Kawamata, Hiroyuki Yokota, Shin-Ichiro Kumita

    Acta radiologica short reports   3 ( 1 )   2047981613518772 - 2047981613518772   2014.1

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    To date, no ideal endovascular strategy has been established for traumatic arterial occlusion. Here, we report the outcomes of a combination of endovascular recanalization techniques applied in two patients with high risk of leg amputation. A 33-year-old man with popliteal artery occlusion due to blunt trauma was treated by balloon angioplasty with long inflation time and aspiration thrombectomy. A 74-year-old woman with popliteal artery occlusion after total knee replacement was treated by aspiration thrombectomy and stent placement. In both cases, we achieved satisfactory recanalization, and peripheral ischemia was absent even 1 year later.

    DOI: 10.1177/2047981613518772

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  • Improved efficacy of transcatheter arterial chemoembolization using warmed miriplatin for hepatocellular carcinoma. International journal

    Daisuke Yasui, Satoru Murata, Shiro Onozawa, Takahiko Mine, Tatsuo Ueda, Fumie Sugihara, Chiaki Kawamoto, Eiji Uchida, Shin-ichiro Kumita

    BioMed research international   2014   359296 - 359296   2014

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    The aim of this study was to evaluate the efficacy and safety of transcatheter arterial chemoembolization (TACE) using warmed and nonwarmed miriplatin for hepatocellular carcinoma. Eighty patients (117 nodules), treated between January 2010 and June 2013, were evaluated. Thirty-two and 85 nodules were treated with nonwarmed and warmed miriplatin, respectively. The efficacy of TACE was evaluated on a per nodule basis according to treatment effect (TE). Adverse events were evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0. TE grades were significantly improved in the warmed group compared to the nonwarmed group (nonwarmed: TE 4, 12.5%; TE 3, 0%; TE 2, 15.6%; TE 1, 71.9%; warmed: TE 4, 34.1%; TE 3, 5.9%; TE 2, 9.4%; TE 1, 50.6%; P = 0.017) . Multivariate analysis revealed significant impact of warming miriplatin on objective response rate (odds ratio, 12.35; 95% confidence interval, 2.90-90.0; P = 0.0028). CTCAE grades of elevated aspartate and alanine transaminase after TACE were significantly higher in the warmed group (P = 0.0083 and 0.0068, resp.); however, all adverse events were only transient. The use of warmed miriplatin in TACE significantly improved TE without causing serious complications.

    DOI: 10.1155/2014/359296

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  • Comparison of the antitumor efficacy of transcatheter arterial chemoembolization with a miriplatin-iodized oil suspension and a cisplatin-iodized oil suspension for hepatocellular carcinoma. International journal

    Tatsuo Ueda, Satoru Murata, Daisuke Yasui, Takahiko Mine, Shinichiro Kumita

    Hepatology research : the official journal of the Japan Society of Hepatology   43 ( 10 )   1071 - 7   2013.10

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    AIM: To retrospectively compare the short-term antitumor efficacy and safety of transcatheter arterial chemoembolization (TACE) with a cisplatin-iodized oil suspension (C-IS) and a miriplatin-iodized oil suspension (M-IS) for hepatocellular carcinoma (HCC). METHODS: Of patients who underwent TACE for unresectable HCC between January 2010 and August 2011, 25 and 21 patients received C-IS and M-IS, respectively. The short-term therapeutic efficacy of both groups was evaluated by the treatment effect seen on dynamic enhanced computed tomography or magnetic resonance imaging of tumor nodules 3 months after treatment. Adverse events were evaluated to compare C-IS and M-IS. RESULTS: After TACE using C-IS and M-IS, 100% necrosis or tumor size reduction was achieved in 30 and 18 tumor nodules, respectively (81% vs 53%; P = 0.006). Objective responses were achieved in 30 nodules exposed to TACE using C-IS and 17 exposed to TACE using M-IS (81% vs 50%; P = 0.011). Disease control was achieved in 36 nodules exposed to C-IS and 27 exposed to M-IS (97% vs 79%; P = 0.017). The percentage of patients attaining a complete response, an objective response and disease control was significantly greater in the C-IS group than in the M-IS group. No significant differences were found in the aspartate aminotransferase, alanine aminotransferase, total bilirubin and creatinine levels between the two groups either before treatment or 1 month after treatment. CONCLUSION: The short-term antitumor effects of TACE with C-IS may be superior to those with M-IS in terms of the complete response, objective response and disease control rates.

    DOI: 10.1111/hepr.12212

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  • Management of gastric varices unsuccessfully treated by balloon-occluded retrograde transvenous obliteration: long-term follow-up and outcomes. International journal

    Fumio Uchiyama, Satoru Murata, Shiro Onozawa, Ken Nakazawa, Fumie Sugihara, Daisuke Yasui, Yoshiyuki Narahara, Eiji Uchida, Yasuo Amano, Shin-ichiro Kumita

    TheScientificWorldJournal   2013   498535 - 498535   2013

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    Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with gastroesophageal varices refractory to BRTO were treated with PTO (n = 6) or a combination of PTO and BRTO (n = 7). We retrospectively investigated the rates of survival, recurrence, or worsening of the varices; hepatic function before and after the procedure; and complications. The procedure achieved complete obliteration or significant reduction of the varices in all 13 patients without major complications. During follow-up, the varices had recurred in 2 patients, of which one had hepatocellular carcinoma, and the other died suddenly from variceal rebleeding 7 years after PTO. The remaining 11 patients did not experience worsening of the varices and showed significant improvements in the serum ammonia levels and prothrombin time. The mean follow-up period was 90 months, and the cumulative survival rate at 1, 3, and 5 years was 92.9%, 85.7%, and 85.7%, respectively. Both PTO and combined PTO and BRTO seem as safe and effective procedures for the treatment of gastroesophageal varices refractory to BRTO alone.

    DOI: 10.1155/2013/498535

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  • Transcatheter arterial chemoembolization based on hepatic hemodynamics for hepatocellular carcinoma. International journal

    Satoru Murata, Takahiko Mine, Tatsuo Ueda, Ken Nakazawa, Shiro Onozawa, Daisuke Yasui, Shin-ichiro Kumita

    TheScientificWorldJournal   2013   479805 - 479805   2013

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    Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related deaths in the world. The Barcelona Clinic Liver Cancer (BCLC) classification has recently emerged as the standard classification system for clinical management of patients with HCC. According to the BCLC staging system, curative therapies (resection, transplantation, and percutaneous ablation) can improve survival in HCC patients diagnosed at an early stage and offer potential long-term curative effects. Patients with intermediate-stage HCC benefit from transcatheter arterial chemoembolization (TACE), and those diagnosed at an advanced stage receive sorafenib, a multikinase inhibitor, or conservative therapy. Most patients receive palliative or conservative therapy only, and approximately 50% of patients with HCC are candidates for systemic therapy. TACE is often recommended for advanced-stage HCC patients all over the world because these patients desire therapy that is more effective than systemic chemotherapy or conservative treatment. This paper aims to summarize both the published data and important ongoing studies for TACE and to discuss technical improvements in TACE for advanced-stage HCC.

    DOI: 10.1155/2013/479805

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Misc.

  • 当院におけるnon-vascular interventionの工夫について

    安井 大祐, 小谷 映午, 関根 鉄朗

    神奈川医学会雑誌   52 ( 1 )   70 - 70   2025.1

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  • コルヒチン過量服用による薬物中毒の1例

    飯塚 俊太, 関根 鉄朗, 一色 彩子, 小谷 映午, 岩田 琴美, 山根 彩, 安井 大祐, 村松 博之, 嶺 貴彦, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   60回   S431 - S431   2024.9

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  • シャント静脈高血圧症に対し中枢部静脈ステント留置が奏功した症例の検討

    奥畑 好章, 安井 大祐, 久能木 俊之介, 三井 亜希子, 酒井 行直, 柏木 哲也, 岩部 真人

    日本透析医学会雑誌   57 ( Suppl.1 )   448 - 448   2024.5

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  • 内視鏡治療困難な食道噴門部静脈瘤破裂に対して緊急経皮経肝的静脈瘤塞栓術を施行し止血が得られた一例

    安井 大祐, 小谷 映午, 中村 拳, 二神 生爾, 井上 潤一, 関根 鉄朗

    日本インターベンショナルラジオロジー学会雑誌   39 ( Suppl. )   303 - 303   2024.4

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  • TEVARを施行した感染性大動脈周囲膿瘍による大動脈切迫破裂 診断が困難であった稀な1例(Impending Aortic Rupture Caused by Infectious Periaortic Abscess Treated with TEVAR: A Rare Case of Difficult Diagnosis)

    細野 陽介, 田中 匡成, 黄 俊憲, 瀬崎 あやの, 川村 崇, 中島 悠希, 福山 曜, 酒井 伸, 岡 英一郎, 福泉 偉, 細川 雄亮, 丸山 光紀, 圷 宏一, 前田 基博, 廣本 敦之, 鈴木 憲治, 坂本 俊一郎, 小谷 映午, 安井 大祐, 浅井 邦也

    日本循環器学会学術集会抄録集   88回   CRDJ20 - 5   2024.3

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  • CTガイド下生検にて診断し得た肺MALTリンパ腫の一例

    山根 彩, 安井 大祐, 関根 鉄朗

    神奈川医学会雑誌   51 ( 1 )   96 - 97   2024.1

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  • 放射線科IVRのturfを守り広げるために 当院での取り組みについて症例を交えて

    安井 大祐, 小谷 映午, 関根 鉄朗

    神奈川医学会雑誌   51 ( 1 )   99 - 99   2024.1

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  • 中枢静脈閉塞に対する血管内治療におけるperipheral intervention deviceの有用性について

    安井 大祐, 安井 一馬, 山崎 一也, 酒井 政司, 常田 康夫, 藤井 佳美

    透析VAIVT   5   39 - 42   2023.12

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  • 後期分娩後異常出血の原因鑑別に苦慮した1例

    大野 礼, 角田 陽平, 滝澤 彩子, 針金 永佳, 渡邉 朝子, 新村 裕樹, 倉品 隆平, 松島 隆, 鈴木 俊治, 関根 鉄朗, 安井 大祐, 市川 太郎

    関東連合産科婦人科学会誌   60 ( 2 )   264 - 264   2023.5

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  • 外傷性鎖骨下動脈に対して末梢用ステントグラフト内挿術を施行した二症例

    安井 大祐, 安井 一馬, 藤井 佳美

    日本インターベンショナルラジオロジー学会雑誌   38 ( Suppl. )   147 - 147   2023.4

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  • 吐下血により発見された分節性動脈中膜融解(SAM)の1例

    宮里 由規, 城戸 教裕, 大嶽 康介, 平野 瞳子, 吉野 雄大, 渡邊 顕弘, 田上 隆, 望月 徹, 松田 潔, 安井 大祐

    川崎市医師会医学会誌   39   57 - 62   2022.12

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    60歳代男性。上腹部痛、吐血・血便を主訴に救急搬送となった。血液検査では貧血や腎機能の低下がみられ、また造影CT検査では複数の血管にString of beans appearanceが認められ、分節性動脈中膜融解と診断された。治療は内視鏡による機械的刺激で出血の増悪をきたす可能性を考慮し、保存的加療の方針とし、集中治療室にて血圧管理を行った。その結果、循環動態は安定し、貧血の進行もみられず、入院10日後の血管造影検査ではString of beans appearanceの軽快を認めたため、13日目に退院となった。

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  • BCG接種後に生じた皮膚結核様病変のMRI画像所見 3例の自験例の検討

    山根 彩, 安井 大祐, 関根 鉄朗

    日本医学放射線学会秋季臨床大会抄録集   59回   S384 - S384   2022.9

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  • 複雑な血行動態を呈する破裂性胃静脈瘤に対するIVR治療戦略 BRTOと経門脈的あるいは逆行性経静脈的流入路塞栓術併用の有用性について

    安井 大祐, 小谷 映午, 山根 彩, 武田 美那子, 関根 鉄朗, 市川 太郎

    神奈川医学会雑誌   49 ( 1 )   82 - 82   2022.1

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  • 門脈圧亢進症に対するIVR治療~最新の知見と今後の展望~ 機械学習を用いた部分的脾動脈塞栓術の治療効果予測分類器の作成に関する検討

    松本 大河, 安井 大祐, 上田 達夫, 杉原 史恵, 斉藤 英正, 白井 清香, 藤綱 隆太朗, 中込 哲平, 吉岡 正人, 吉田 寛, 林 宏光, 汲田 伸一郎

    日本門脈圧亢進症学会雑誌   27 ( 3 )   74 - 74   2021.8

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  • 【末梢血管用ステントグラフト】下肢動脈に対するステントグラフト治療

    上田 達夫, 杉原 史恵, 斉藤 英正, 白井 清香, 藤綱 隆太朗, 松本 大河, 安井 大祐, 村田 智, 田島 廣之, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( 4 )   335 - 344   2021.5

  • 末梢動脈損傷/出血30例に対するViabahnステントグラフト内挿術 初期および中期成績

    上田 達夫, 齊藤 英正, 杉原 史恵, 白井 清香, 藤綱 隆太朗, 松本 大河, 中込 哲平, 安井 大祐, 水嶋 翔平, 嶺 貴彦, 川俣 博志, 村田 智, 田島 廣之, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   36 ( Suppl. )   165 - 165   2021.4

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  • 全弓部置換術後の左鎖骨下動脈グラフト損傷に対して末梢用ステントグラフトにより止血し得た一例

    松本 大河, 斉藤 英正, 安井 大祐, 上田 達夫, 杉原 史恵, 石井 庸介, 栗田 二郎, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   36 ( Suppl. )   233 - 233   2021.4

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  • 気管支動脈塞栓術が有効であった気管支動脈蔓状血管腫の2例

    橋場 奈月, 中江 竜太, 井上 正章, 前島 璃子, 瀧口 徹, 恩田 秀賢, 金 史英, 増野 智彦, 横堀 將司, 安井 大祐

    日本医科大学医学会雑誌   16 ( 4 )   246 - 246   2020.10

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  • EVAR術前予防的大動脈分枝塞栓術 タイプ2エンドリークと瘤径変化に関する検討

    上田 達夫, 小谷 映午, 斉藤 英正, 杉原 史恵, 安井 大祐, 白井 清香, 藤綱 隆太朗, 松本 大河, 栗田 二郎, 石井 庸介, 師田 哲郎, 林 宏光, 汲田 伸一郎

    脈管学   60 ( Suppl. )   S143 - S143   2020.10

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  • 【MY BOOK MARK 私のお気に入りデバイス】放射線科領域のIVR 血行再建治療におけるFUGA guidewire(Boston Scientific)の汎用性について

    安井 大祐

    Rad Fan   18 ( 11 )   12 - 13   2020.9

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  • 血管型エーラスダンロス症候群に合併した固有肝動脈瘤に対して経皮的動脈塞栓術を施行した一例

    安井 大祐, 杉原 史恵, 斎藤 英正, 田中 泉, 白井 清香, 藤綱 隆太朗, 松本 大河, 圷 宏一, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   263 - 263   2020.8

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  • ステントグラフト術前の腹部大動脈分枝塞栓術 type2 endoleak発生と瘤径変化に与える影響

    上田 達夫, 小谷 映午, 斉藤 英正, 杉原 史恵, 安井 大祐, 田中 泉, 白井 清香, 藤綱 隆太朗, 松本 大河, 栗田 二郎, 師田 哲郎, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   188 - 188   2020.8

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  • 複雑性虫垂炎に対するCTガイド下ドレナージの有用性および再発予測因子の検討

    白井 清香, 杉原 史恵, 安井 大祐, 齊藤 英正, 藤綱 隆太朗, 松本 大河, 上田 達夫, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   206 - 206   2020.8

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  • 膵仮性嚢胞内に生じた仮性動脈瘤に対するNBCAを用いた経皮的動脈塞栓術の安全性と有効性に関する検討

    安井 大祐, 杉原 史恵, 上田 達夫, 斎藤 英正, 田中 泉, 白井 清香, 藤綱 隆太朗, 松本 大河, 金子 恵子, 横堀 將司, 横田 裕行, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   226 - 226   2020.8

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  • 早期機能不全を呈したAVFに対するVascular Access Intervention Therapyの有効性と安全性

    藤綱 隆太朗, 杉原 史恵, 安井 大祐, 齋藤 英正, 白井 清香, 松本 大河, 上田 達夫, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   160 - 160   2020.8

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  • 機械学習を用いた部分的脾動脈塞栓術の治療効果予測に関する検討

    松本 大河, 安井 大祐, 杉原 史恵, 斉藤 英正, 吉田 寛, 吉岡 正人, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   179 - 179   2020.8

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  • 急性大動脈解離発症前後の造影CTを用いた急性大動脈解離発症前の大動脈径の推定

    齊藤 英正, 上田 達夫, 林 宏光, 杉原 史恵, 安井 大祐, 田中 泉, 白井 清香, 藤綱 隆太郎, 松本 大河, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   35 ( Suppl. )   243 - 243   2020.8

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  • 脾機能亢進に伴う血球減少に対する治療戦略~薬物vs IVR vs手術~ 脾機能亢進に伴う血小板低下に対する部分的脾動脈塞栓術の役割について

    安井 大祐

    日本門脈圧亢進症学会雑誌   25 ( 3 )   86 - 86   2019.9

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  • 門亢症に対するIVR治療の進歩~難治例・難渋例に対する工夫~ 腸管壊死を伴う超重症門脈血栓症に対して、腸管切除及び開腹下IVRによるハイブリッド治療により良好な転機を辿った2例

    白井 清香, 上田 達夫, 杉原 史恵, 安井 大祐, 斉藤 英正, 金 史英, 横田 裕行, 吉田 寛, 汲田 伸一郎

    日本門脈圧亢進症学会雑誌   25 ( 3 )   62 - 62   2019.9

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  • 無漿膜野の肝細胞癌に対してマイクロバルーンによる血流改変下に肝動脈化学塞栓術を行った一例

    白井 清香, 安井 大祐, 上田 達夫, 杉原 史恵, 斉藤 英正, 葉山 惟信, 川本 智章, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   352 - 352   2019.5

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  • 動脈損傷に対するVIABAHNステントグラフト治療15例の初期および中期成績

    上田 達夫, 杉原 史恵, 安井 大祐, 齋藤 英正, 田中 泉, 白井 清香, 小谷 映午, 村田 智, 田島 廣之, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   294 - 294   2019.5

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  • Triaxial B-glue Systemを用いた加温Glueによる血管塞栓術

    嶺 貴彦, 水嶋 翔平, 樫村 剛司, 上嶋 聡, 安井 大祐, 上田 達夫

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   309 - 309   2019.5

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  • 動脈瘤ステントグラフト内挿術後のtype 2 endoleakに対するIVR 経動脈的塞栓術と経皮的塞栓術の比較検討

    齊藤 英正, 上田 達夫, 杉原 史恵, 安井 大祐, 田中 泉, 白井 清香, 小谷 映午, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   251 - 251   2019.5

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  • 腹部大動脈瘤に対するステントグラフト術前の予防的大動脈分枝塞栓術の有用性に関する検討

    小谷 映午, 上田 達夫, 杉原 史恵, 安井 大祐, 齋藤 英正, 田中 泉, 白井 清香, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   253 - 253   2019.5

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  • 下部消化管出血に対するN-butyl Cyanoacrylateを用いた塞栓術の有効性と安全性に関する検討

    田中 泉, 上田 達夫, 杉原 史恵, 安井 大祐, 斉藤 英正, 白井 清香, 小谷 映午, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   270 - 270   2019.5

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  • VX2担癌ウサギを用いた単分散系ミリプラチン懸濁液の安全性と有効性に関する検討(Experiment on the safety and efficacy of mono-disperse miriplatin emulsion using VX-2 rabbit model)

    安井 大祐, 村田 智, 上田 達夫, 杉原 史恵, 斎藤 英正, 白井 清香, 伊藤 博, 小林 正行, 汲田 伸一郎

    日本インターベンショナルラジオロジー学会雑誌   34 ( Suppl. )   282 - 282   2019.5

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  • 【救急IVRの最前線】動脈損傷に対するゴアバイアバーンステントグラフトを用いた血管内治療

    上田 達夫, 村田 智, 田島 廣之, 杉原 史恵, 安井 大祐, 斎藤 英正, 汲田 伸一郎

    Rad Fan   17 ( 5 )   44 - 48   2019.4

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    動脈損傷に対するゴアバイアバーンステントグラフトを用いた血管内治療は末梢臓器血流を維持したまま止血を行うことが可能な理想的な治療法である。2016年12月に血管損傷に対する適応が保険認可されて以来、急速に普及してきている。本稿では、本デバイスの特徴・適応などの基本事項および実際に使用する上での注意点や問題点について解説する。(著者抄録)

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  • 経上腸間膜静脈アプローチでのIVRによる血栓除去術が奏功した超重症門脈血栓閉塞症の2例

    白井 清香, 上田 達夫, 杉原 史恵, 安井 大祐, 斉藤 英正, 横田 裕行, 吉田 寛, 汲田 伸一郎

    日本腹部救急医学会雑誌   39 ( 2 )   452 - 452   2019.2

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  • 複数科の連携により救命した腹部大動脈瘤破裂の1例

    原口 尚子, 重田 健太, 遠山 健太郎, 尤 礼佳, 石木 義人, 中江 竜太, 原 義明, 横田 裕行, 中田 淳, 山本 剛, 清水 渉, 宮城 泰雄, 新田 隆, 安井 大祐, 上田 達夫, 汲田 伸一郎

    日本医科大学医学会雑誌   14 ( 4 )   206 - 206   2018.10

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  • 分節性動脈中膜融解(Segmental Arterial Mediolysis:SAM)による腹腔内出血を来たした1例

    遠山 健太郎, 尤 礼佳, 重田 健太, 石木 義人, 中江 竜太, 増野 智彦, 原 義明, 新井 正徳, 辻井 厚子, 横田 裕行, 斉藤 英正, 星野 慎太朗, 安井 大祐, 杉原 史恵

    日本医科大学医学会雑誌   14 ( 4 )   206 - 206   2018.10

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  • 重症門脈血栓症に対する経門脈・経脾静脈的血行再建術の有効性

    齊藤 英正, 村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 横田 裕行, 川本 智章, 金子 恵子, 葉山 惟信, 吉田 寛, 谷合 信彦, 田島 廣之, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   54回   S484 - S484   2018.9

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  • 重症門脈血栓症に対する経門脈・経脾静脈的血行再建術の治療成績

    齊藤 英正, 村田 智, 上田 達夫, 林 宏光, 杉原 史恵, 安井 大祐, 横田 裕行, 川本 智章, 金子 恵子, 葉山 惟信, 吉田 寛, 谷合 信彦, 汲田 伸一郎

    脈管学   58 ( Suppl. )   S163 - S163   2018.9

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  • 急性下肢虚血95例104肢に対するIVR治療成績

    上田 達夫, 杉原 史恵, 安井 大祐, 齋藤 英正, 田中 泉, 栗田 二郎, 師田 哲郎, 清水 渉, 林 宏光, 汲田 伸一郎

    脈管学   58 ( Suppl. )   S195 - S195   2018.9

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  • 腹部血管損傷に対するカバーステント治療の初期経験

    上田 達夫, 村田 智, 齊藤 英正, 安井 大祐, 杉原 史恵, 内田 英二, 汲田 伸一郎

    日本腹部救急医学会雑誌   38 ( 2 )   417 - 417   2018.2

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  • 急速な動脈瘤の発達及び腹腔内出血を生じたSegmental arterial mediolysis(SAM)に対し経皮的動脈塞栓術(TAE)を施行した1例

    齊藤 英正, 村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 田島 廣之, 横田 裕行, 汲田 伸一郎

    日本腹部救急医学会雑誌   38 ( 2 )   456 - 456   2018.2

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  • 血管損傷に対するステントグラフト(VIABAHNR)治療の初期経験

    齊藤 英正, 村田 智, 上田 達夫, 林 宏光, 杉原 史恵, 安井 大祐, 田島 廣之, 内田 英二, 清水 渉, 圷 宏一, 汲田 伸一郎

    脈管学   57 ( Suppl. )   S138 - S138   2017.10

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  • 高度石灰化を伴う長区域の浅大腿動脈慢性完全閉塞に対し、subintimal approachにより血行再建に成功した一例

    田中 泉, 村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 齊藤 英正, 清水 渉, 汲田 伸一郎

    脈管学   57 ( Suppl. )   S255 - S256   2017.10

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  • 【MY BOOK MARK 私のお気に入りデバイス】放射線科領域のIVR マイクロカテーテル GOLD CREST Neoについて

    安井 大祐

    Rad Fan   15 ( 12 )   68 - 69   2017.10

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  • 浅大腿動脈(SFA)・深大腿動脈(DFA)の多発仮性動脈瘤に対してカバードステント(VIABAHNR)留置と経皮的動脈塞栓術(TAE)の併用が有用であった1例

    齊藤 英正, 村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 高木 亮, 田島 廣之, 清水 渉, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   53回   S550 - S550   2017.8

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  • 重症門脈血栓症に対するIVR治療成績と適応の検討

    齊藤 英正, 村田 智, 三樹 いずみ, 安井 大祐, 杉原 史恵, 上田 達夫, 葉山 惟信, 福田 健, 金子 恵子, 川本 智章, 谷合 信彦, 汲田 伸一郎

    IVR: Interventional Radiology   32 ( Suppl. )   234 - 234   2017.4

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  • AMPLATZER VASCULAR Plugの適用とテクニック AVP 4を中心に

    村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 齊藤 英正, 三樹 いずみ, 小野澤 志郎, 汲田 伸一郎

    Rad Fan   15 ( 5 )   2 - 5   2017.4

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  • 肝動脈バルーン閉塞下での肝細胞癌および肝実質の血流動態の変化

    杉原 史恵, 村田 智, 上田 達夫, 安井 大祐, 齋藤 英正, 川本 智章, 内田 英二, 汲田 伸一郎

    IVR: Interventional Radiology   32 ( Suppl. )   175 - 175   2017.4

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  • 産科的処置にて制御困難な産科出血に対する経皮的動脈塞栓術の有用性

    安井 大祐, 村田 智, 上田 達夫, 杉原 史恵, 齋藤 英正, 米澤 美令, 竹下 俊行, 汲田 伸一郎

    IVR: Interventional Radiology   32 ( Suppl. )   178 - 178   2017.4

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  • 治療抵抗性・再発子宮頸癌に対する閉鎖循環下骨盤内非均衡灌流療法(NIPP)

    杉原 史恵, 村田 智, 上田 達夫, 安井 大祐, 齋藤 英正, 鈴木 健一, 坂本 篤裕, 汲田 伸一郎

    IVR: Interventional Radiology   32 ( Suppl. )   182 - 182   2017.4

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  • 急性上肢虚血に対するIVR治療戦略に関する検討

    上田 達夫, 村田 智, 斉藤 英正, 三樹 いずみ, 安井 大祐, 杉原 史恵, 師田 哲郎, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   32 ( Suppl. )   192 - 192   2017.4

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  • 重症急性膵炎に対する膵局所動注療法の治療効果と合併症

    三樹 いずみ, 村田 智, 上田 達夫, 杉原 史恵, 安井 大祐, 齊藤 英正, 横田 裕行, 汲田 伸一郎

    日本腹部救急医学会雑誌   37 ( 2 )   291 - 291   2017.2

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  • 産科出血に対する経皮的動脈塞栓術の有用性に関する検討

    安井 大祐, 村田 智, 上田 達夫, 杉原 史恵, 竹下 俊行, 汲田 伸一郎

    日本腹部救急医学会雑誌   37 ( 2 )   279 - 279   2017.2

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  • 急性上肢虚血に対するIVR治療戦略に関する検討

    上田 達夫, 村田 智, 林 宏光, 斉藤 英正, 三樹 いずみ, 安井 大祐, 杉原 史恵, 村上 隆介, 圷 宏一, 師田 哲郎, 田島 廣之, 汲田 伸一郎

    脈管学   56 ( Suppl. )   S144 - S144   2016.10

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  • Zenith stentgraft 2000の破損・修復後に生じたtype IIIエンドリークによる大動脈瘤破裂に対して再修復を行った1例

    齊藤 英正, 村田 智, 上田 達夫, 林 宏光, 三樹 いずみ, 安井 大祐, 杉原 史恵, 村上 隆介, 圷 宏一, 師田 哲郎, 田島 廣之, 汲田 伸一郎

    脈管学   56 ( Suppl. )   S220 - S220   2016.10

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  • 【若い世代から増えている女性のがん】子宮がん 子宮がんの血管内治療

    村田 智, 杉原 史恵, 上田 達夫, 山口 英紀, 安井 大祐, 三樹 いずみ, 小野澤 志郎, 坂本 篤裕, 鈴木 健, 汲田 伸一郎

    臨牀と研究   93 ( 6 )   831 - 837   2016.6

  • 治療抵抗性および再発子宮頸癌における閉鎖循環下骨盤内灌流化学療法(NIPP)の治療成績

    杉原 史恵, 村田 智, 上田 達夫, 安井 大祐, 三樹 いずみ, 齋藤 英正, 小野澤 志郎, 坂本 篤裕, 汲田 伸一郎

    IVR: Interventional Radiology   31 ( Suppl. )   193 - 193   2016.4

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  • ビーズ導入後のTACEの現状 Lipiodol-TACE不応肝細胞癌に対するDEB-TACEの治療効果に関する検討

    齊藤 英正, 村田 智, 三樹 いずみ, 安井 大祐, 杉原 史恵, 上田 達夫, 山口 英宣, 川本 智章, 谷合 信彦, 汲田 伸一郎

    IVR: Interventional Radiology   31 ( Suppl. )   115 - 115   2016.4

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  • 経皮経肝穿刺が困難な症例に対する経皮経脾静脈アプローチによる門脈系IVR

    安井 大祐, 村田 智, 上田 達夫, 山口 英宣, 杉原 史恵, 三樹 いずみ, 齋藤 英正, 川本 智章, 横田 裕行, 汲田 伸一郎

    IVR: Interventional Radiology   31 ( Suppl. )   142 - 142   2016.4

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  • 穿刺部出血に対してバルーン閉塞下NBCA塞栓術が有用であった2例

    上田 達夫, 村田 智, 杉原 史恵, 安井 大祐, 三樹 いずみ, 齋藤 英正, 汲田 伸一郎

    IVR: Interventional Radiology   31 ( Suppl. )   227 - 227   2016.4

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  • 腹部外傷における腹腔内出血コントロール Interventional Radiology vs Damage 腹腔内出血を伴う重症肝損傷および脾損傷に対するIVR

    杉原 史恵, 村田 智, 上田 達夫, 安井 大祐, 三樹 いずみ, 斉藤 正英, 汲田 伸一郎, 横田 裕行

    日本腹部救急医学会雑誌   36 ( 2 )   337 - 337   2016.2

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  • 術後出血に対するInterventional Radiologyの適応と限界 術後出血に対する固有・総肝動脈のIsolationの有効性と安全性に関する検討

    安井 大祐, 村田 智, 上田 達夫, 杉原 史恵, 汲田 伸一郎, 谷合 信彦, 内田 英二

    日本腹部救急医学会雑誌   36 ( 2 )   347 - 347   2016.2

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  • 外傷性胸部大動脈損傷により動脈管索内に血流を認めた1例

    武田 美那子, 林 宏光, 上田 達夫, 斉藤 英正, 嶺 貴彦, 三樹 いずみ, 安井 大祐, 杉原 史恵, 小野澤 志郎, 高木 亮, 村田 智, 横田 裕行, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   51回   S566 - S566   2015.9

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  • 副腎静脈サンプリング前のthin slice CTの右副腎静脈描出能と有用性に関する検討

    小野澤 志郎, 田島 廣之, 上田 達夫, 杉原 史恵, 安井 大祐, 三樹 いずみ, 杉原 仁, 村田 智

    静脈学   26 ( 2 )   178 - 178   2015.6

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  • 肺動脈血栓塞栓症 急性肺血栓塞栓症におけるハイブリッドIVRの実際とその治療成績

    三樹 いずみ, 田島 廣之, 小野澤 志郎, 金城 忠志, 竹ノ下 尚子, 安井 大祐, 杉原 史恵, 上田 達夫, 村田 智, 中澤 賢

    静脈学   26 ( 2 )   121 - 121   2015.6

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  • 感染性右総腸骨動脈瘤に対してin situ fenestration EVARを施行した1例

    芝田 匡史, 小野澤 志郎, 三樹 いずみ, 安井 大祐, 上田 達夫, 村田 智, 師田 哲郎, 汲田 伸一郎, 新田 隆

    日本外科系連合学会誌   40 ( 3 )   609 - 609   2015.5

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  • 【IVR治療戦略:術前に必要な画像診断はこれだ!】原発性肝細胞癌に対するTACEに必要な画像診断の実際

    村田 智, 田島 廣之, 杉原 史恵, 小野澤 志郎, 上田 達夫, 安井 大祐, 三樹 いずみ, 内山 史生, 山口 英宣, 嶺 貴彦, 汲田 伸一郎

    臨床画像   31 ( 5 )   567 - 576   2015.5

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  • 腹部領域の救急医療におけるIVRの役割 腹部救急医療に対するIVR医の役割

    上田 達夫, 村田 智, 小野澤 志郎, 杉原 史恵, 安井 大祐, 三樹 いずみ, 山口 英宣, 田島 廣之, 増野 智彦, 横田 裕行, 内田 英二, 汲田 伸一郎

    日本外科系連合学会誌   40 ( 3 )   558 - 558   2015.5

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  • 消化管出血に対する動脈塞栓術 術前CTの手技への影響に関する検討

    安井 大祐, 村田 智, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 杉原 史恵, 三樹 いずみ, 坂本 長逸, 内田 英二, 横田 裕行, 汲田 伸一郎

    臨床放射線   60 ( 4 )   564 - 572   2015.4

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    経カテーテル的動脈塞栓術(TAE)を行った62例(男性46例、女性16例、平均64.9歳)を対象に、術前造影CTが消化管出血に対する影響について検討した。TAEは上部消化管出血に48回、下部消化管出血に21回の計69回行い、全例で技術的成功が得られた。TAEでの止血は56例(臨床的成功率90.3%)で得られ、残る6例に追加TAEを行い、うち5例で止血が得られ、1例は止血困難で死亡した。院内死亡は10例(16.1%、出血死1、原病死5、敗血症・多臓器不全死3、コレステリン塞栓1)であった。術前造影CTを行った29例中20例(69.0%、上部消化管60.0%、下部消化管88.9%)で活動性出血を認め、残る5例では血管造影でも活動性出血は認めず、選択的造影で血管外漏出を認めた。血管造影での出血検出率は45例(65.2%)であった。塞栓までの平均時間は上部消化管33.1分、下部消化管45.2分であった。術前CTの有無は、活動性出血検出率および塞栓までの時間に有意な影響を与えなかった。

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  • 【腎泌尿器のインターベンショナル・ラジオロジー】血管性 診断におけるインターベンショナル・ラジオロジー サンプリング

    小野澤 志郎, 村田 智, 嶺 貴彦, 上田 達夫, 杉原 史恵, 安井 大祐, 三樹 いずみ, 金城 忠志, 杉原 仁, 田島 廣之

    腎臓内科・泌尿器科   1 ( 4 )   318 - 322   2015.4

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  • 【腎・泌尿生殖器update 2015】血管造影に基づく副腎静脈吻合の解剖学的特徴

    杉原 史恵, 小野澤 志郎, 村田 智, 田島 廣之, 嶺 貴彦, 山口 英宜, 上田 達夫, 安井 大祐, 木村 隆誉, 三樹 いずみ, 杉原 仁, 汲田 伸一郎

    臨床放射線   60 ( 3 )   420 - 427   2015.3

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    当院で副腎静脈サンプリングを施行した145例を対象に、血管造影画像に基づく副腎静脈の吻合様式について検討した。その結果、副腎静脈において吻合血管が描出されたのは右側で128例(88.3%)、左側で136例(93.8%)であった。右副腎静脈との吻合血管の種類と頻度は、それぞれ腎被膜静脈80.7%、後腹膜静脈33.1%、下横隔静脈11.0%、肝静脈5.5%、門脈5.5%、腎盂尿管静脈1.4%であった。右下肝静脈と右副腎静脈の共通幹形成は4.1%で認められた。左副腎静脈との吻合血管は、腎被膜静脈56.6%、後胃静脈9.7%、後腹膜静脈7.6%、腎盂尿管静脈1.4%、腰静脈0.7%であった。左下横隔静脈との共通幹形成は89.7%と高頻度にみられた。

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  • 腹腔内出血を伴う腹部外傷に対するIVR

    安井 大祐, 村田 智, 小野澤 志郎, 嶺 貴彦, 汲田 伸一郎, 谷合 信彦, 内田 英二, 横田 裕行

    日本腹部救急医学会雑誌   35 ( 2 )   417 - 417   2015.2

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  • EVAR前の内腸骨動脈塞栓におけるAmplatzer Vascular Plug使用の初期経験

    小野澤 志郎, 田島 廣之, 村田 智, 林 宏光, 嶺 貴彦, 安井 大祐, 汲田 伸一郎

    血管外科   33 ( 1 )   164 - 164   2014.11

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  • 【非静脈瘤性消化管出血の治療戦略】出血性上部消化管潰瘍に対するNBCA塞栓術 循環への寄与と粘膜治癒の経過

    嶺 貴彦, 村田 智, 小野澤 志郎, 上田 達夫, 山口 英宣, 杉原 史恵, 安井 大祐, 宮内 雅人, 田島 廣之, 汲田 伸一郎

    日本腹部救急医学会雑誌   34 ( 7 )   1289 - 1293   2014.11

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    内視鏡的止血困難例26例を対象に,出血性上部消化管潰瘍に対するN-butyl-2-cyanoacrylate(NBCA)を用いた動脈塞栓術後の循環動態変化と粘膜治癒過程に関する評価・検討を行った。塞栓術により全例で即時的な止血と有意な循環動態の改善が確認された。塞栓術前の潰瘍病変は全例Forrest I(Ia 20,Ib 6)であり,塞栓術後には明らかな虚血性粘膜障害は認められず,11±7.9日でForrest IIIまでの改善が確認された。NBCAは適正な使用下では潰瘍治癒過程において大きな妨げにはならないものと考えられ,安全かつ有用性の高い塞栓物質であると考えられた。(著者抄録)

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2014&ichushi_jid=J02824&link_issn=&doc_id=20141219440008&doc_link_id=10.11231%2Fjaem.34.1289&url=https%3A%2F%2Fdoi.org%2F10.11231%2Fjaem.34.1289&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_2.gif

  • 小腸の壊死を伴う門脈血栓症に対するインターベンショナルラジオロジーと外科手術の併用療法 1症例報告(Combination therapy of interventional radiology and surgery for portal vein thrombosis with necrosis of small intestine: a case report)

    木村 隆誉, 村田 智, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 安井 大祐, 杉原 史恵, 三樹 いずみ, 池田 慎平, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   50回   S680 - S680   2014.9

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  • 活動性出血を伴う肝内門脈裂傷に対して経皮経肝アプローチでNBCA塞栓術を施行した1例

    嶺 貴彦, 村田 智, 小野澤 志郎, 山口 英宣, 杉原 史恵, 木村 隆誉, 安井 大祐, 三樹 いずみ, 池田 慎平, 新井 正徳, 横田 裕行, 田島 廣之, 汲田 伸一郎

    日本医学放射線学会秋季臨床大会抄録集   50回   S731 - S732   2014.9

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  • 肝内門脈末梢枝の裂傷に対して経皮経肝アプローチで門脈塞栓術を施行した1例

    嶺 貴彦, 村田 智, 小野澤 志郎, 山口 英宣, 杉原 史恵, 安井 大祐, 池田 慎平, 金 史恵, 新井 正徳, 横田 裕行, 汲田 伸一郎, 田島 廣之

    Japanese Journal of Acute Care Surgery   4 ( 2 )   238 - 238   2014.9

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  • 【NBCA塞栓術の現状と病理組織学的影響】消化管出血に対するNBCAを用いた塞栓術

    嶺 貴彦, 安井 大祐, 村田 智, 小野澤 志郎, 上田 達夫, 山口 英宣, 杉原 史恵, 川俣 博志, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( 3 )   243 - 251   2014.8

  • 子宮頸癌における閉鎖循環下骨盤内灌流化学療法(NIPP)治療成績

    杉原 史恵, 村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 上田 達夫, 安井 大祐, 三樹 いずみ, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   162 - 162   2014.5

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  • AMPLATZER Vascular Plugの適応と塞栓時間短縮に向けて

    村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 安井 大祐, 杉原 史恵, 三樹 いずみ, 上田 達夫, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   121 - 121   2014.5

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  • 非外傷性腹腔内出血に対する経皮的動脈塞栓術の有用性に関する検討

    安井 大祐, 村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 杉原 史恵, 秋葉 絢子, 三樹 いずみ, 今井 祥吾, 山多 芙美, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   152 - 152   2014.5

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  • AVP2による末梢側塞栓とUpside-down techniqueを用いたZenith脚留置により内腸骨動脈瘤を閉鎖した一例

    山多 芙美, 村田 智, 小野澤 志郎, 嶺 貴彦, 栗田 二郎, 山口 英宣, 上田 達夫, 杉原 史恵, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 師田 哲郎, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   240 - 240   2014.5

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  • 腹部大動脈の著明な石灰化による全周性高度狭窄病変に対しステント治療により下肢症状の改善を得た1例

    今井 祥吾, 小野澤 志郎, 村田 智, 嶺 貴彦, 山口 英宜, 秋葉 絢子, 杉原 史恵, 安井 大祐, 三樹 いずみ, 山多 芙美, 師田 哲郎, 栗田 二郎, 圷 宏一, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   273 - 273   2014.5

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  • 自作ステントグラフトを用いたEVAR後の遠隔期トラブルを企業製ステントグラフトで修復した2治療経験

    嶺 貴彦, 小野澤 志郎, 村田 智, 市川 和雄, 栗田 二郎, 山口 英宣, 杉原 史恵, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 師田 哲郎, 林 宏光, 吉川 公彦, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   307 - 307   2014.5

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  • 肝硬変を伴わない進行肝がんに対する経皮的逆行性門脈吸引肝灌流療法(Phase 1 study)

    村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 杉原 史恵, 安井 大祐, 三樹 いずみ, 上田 達夫, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   162 - 162   2014.5

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  • AMPLATZER Vascular Plug II(AVP II)の使用経験

    嶺 貴彦, 村田 智, 小野澤 志郎, 山口 英宣, 上田 達夫, 杉原 史恵, 安井 大祐, 三樹 いずみ, 今井 祥吾, 山多 芙美, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   186 - 186   2014.5

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  • 急性四肢動脈閉塞に対するIVR治療成績の検討

    上田 達夫, 村田 智, 三樹 いずみ, 安井 大祐, 杉原 史恵, 山口 英宣, 嶺 貴彦, 小野澤 志郎, 田島 廣之, 落 雅美, 横田 裕行, 汲田 伸一郎

    IVR: Interventional Radiology   29 ( Suppl. )   193 - 193   2014.5

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  • 肝細胞癌に対する肝動脈化学塞栓術における加温ミリプラチンの治療効果及び安全性に関する検討

    安井 大祐, 村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 杉原 史恵, 秋葉 絢子, 三樹 いずみ, 汲田 伸一郎, 川本 智章, 谷合 信彦

    肝臓   55 ( Suppl.1 )   A275 - A275   2014.4

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  • 副腎静脈サンプリングにおける副腎静脈吻合の検討

    杉原 史恵, 小野澤 志郎, 村田 智, 田島 廣之, 山口 英宜, 嶺 貴彦, 安井 大祐, 三樹 いずみ, 杉原 仁, 汲田 伸一郎

    静脈学   25 ( 2 )   159 - 159   2014.3

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  • 副腎静脈サンプリング施行前のthin slice CTの右副腎静脈同定とangioCTにおける一致性について

    三樹 いずみ, 小野澤 志郎, 村田 智, 田島 廣之, 山口 英宜, 嶺 貴彦, 杉原 史恵, 安井 大祐, 杉原 仁, 林 宏光, 汲田 伸一郎

    静脈学   25 ( 2 )   158 - 158   2014.3

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  • 腹腔内出血に対するIVR 非外傷性腹腔内出血に対するIVR治療

    安井 大祐, 村田 智, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 杉原 史恵, 三樹 いずみ, 汲田 伸一郎, 吉岡 正人, 川本 智章

    日本腹部救急医学会雑誌   34 ( 2 )   394 - 394   2014.2

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  • 副腎静脈サンプリング施行前のthin slice CTによる右副腎静脈同定の有用性

    山口 英宣, 小野澤 志郎, 田島 廣之, 嶺 貴彦, 村田 智, 杉原 史恵, 安井 大祐, 杉原 仁, 林 宏光, 汲田 伸一郎

    静脈学   24 ( 2 )   193 - 193   2013.5

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  • Budd-Chiari症候群に対して経皮経肝的アプローチによる肝静脈形成術を施行した1例

    會田 久美子, 村田 智, 中澤 賢, 小野澤 志郎, 山口 英宣, 嶺 貴彦, 杉原 史恵, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   154 - 154   2013.4

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  • 小腸出血におけるIVRの有用性と予後因子に関する検討

    杉原 史恵, 村田 智, 中澤 賢, 小野澤 志郎, 嶺 貴彦, 山口 英宜, 上田 達夫, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 會田 久美子, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   174 - 174   2013.4

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  • 肝細胞癌に対する肝動脈化学塞栓術における加温ミリプラチンの有用性に関する検討

    安井 大祐, 村田 智, 中澤 賢, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 杉原 史恵, 秋葉 絢子, 三樹 いずみ, 會田 久美子, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   137 - 137   2013.4

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  • 安全な肝切除術を得るための門脈塞栓術による代償性肝肥大の検討

    秋葉 絢子, 村田 智, 中澤 賢, 小野澤 志郎, 山口 英宣, 杉原 史恵, 安井 大祐, 三樹 いずみ, 川野 陽一, 吉原 尚志, 山口 敏雄

    IVR: Interventional Radiology   28 ( Suppl. )   135 - 135   2013.4

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  • 新たな塞栓デバイス AMPLATZER Vascular Plug

    村田 智, 嶺 貴彦, 小野澤 志郎, 杉原 史恵, 安井 大祐, 山口 英宣, 秋葉 絢子, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   120 - 120   2013.4

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  • 出血性胃十二指腸潰瘍に対するNBCA塞栓術後の粘膜障害の評価

    嶺 貴彦, 村田 智, 中澤 賢, 小野澤 志郎, 上田 達夫, 山口 英宣, 杉原 史恵, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 會田 久美子, 川俣 博志, 進藤 惠美, 田島 廣之, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   173 - 174   2013.4

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  • 臓器虚血が出現したStanford B型急性大動脈解離に対し経皮的腹部大動脈開窓術を施行した一例

    三樹 いずみ, 村田 智, 小野澤 志郎, 中澤 賢, 嶺 貴彦, 上田 達夫, 山口 英宜, 杉原 史恵, 秋葉 絢子, 安井 大祐, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   169 - 170   2013.4

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  • 孤立性腹腔内臓動脈解離に対するIVR治療の有用性

    山口 英宣, 村田 智, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 杉原 史恵, 安井 大祐, 三樹 いずみ, 林 宏光, 汲田 伸一郎

    IVR: Interventional Radiology   28 ( Suppl. )   168 - 168   2013.4

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  • 肝細胞癌に対する肝動脈化学塞栓術における加温ミリプラチンによる治療効果の向上に関する検討(Improved efficacy of warmed miriplatin compared with non-warmed one in transarterial chemoembolization for hepatocellular carcinoma)

    安井 大祐, 村田 智, 中澤 賢, 小野澤 志郎, 山口 英宣, 杉原 史恵, 秋葉 絢子, 三樹 いずみ, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   72回   S273 - S273   2013.2

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  • NBCAを用いたIVRの実際 私はこうしている NBCAを用いたIVRの実際

    小野澤 志郎, 田島 廣之, 村田 智, 中澤 賢, 山口 英宣, 杉原 史恵, 安井 大祐, 金城 忠志, 竹ノ下 尚子, 上田 達夫, 嶺 貴彦

    臨床画像   29 ( 2 )   256 - 264   2013.2

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  • 小腸出血に対するIVRの有用性

    杉原 史恵, 村田 智, 小野澤 志郎, 中澤 賢, 嶺 貴彦, 上田 達夫, 山口 英宣, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 武田 美那子, 汲田 伸一郎

    日本腹部救急医学会雑誌   33 ( 2 )   453 - 453   2013.2

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  • 孤立性腹腔内臓動脈解離に対するIVR治療の有用性

    山口 英宣, 村田 智, 小野澤 志郎, 中澤 賢, 杉原 史恵, 安井 大祐, 林 宏光, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   72回   S218 - S219   2013.2

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  • 小腸出血におけるIVRの有用性

    杉原 史恵, 村田 智, 中澤 賢, 小野澤 志郎, 山口 英宣, 秋葉 絢子, 安井 大祐, 三樹 いずみ, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   72回   S263 - S264   2013.2

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  • 小腸AVMに対し永久液体塞栓物質による血管塞栓術が有効であった1例

    武田 美那子, 村田 智, 林 宏光, 中澤 賢, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 山口 英宣, 秋葉 絢子, 安井 大祐, 汲田 伸一郎

    血管外科   31 ( 1 )   165 - 165   2012.11

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  • 当院におけるSorafenibの臨床使用経験

    宮元 亮子, 金子 恵子, 清水 秀治, 川本 智章, 水野 杏一, 安井 大祐, 秋葉 絢子, 中澤 賢, 村田 智, 清水 哲也, 川野 陽一, 谷合 信彦, 真々田 裕宏

    日本消化器病学会雑誌   109 ( 臨増大会 )   A718 - A718   2012.9

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  • 繰り返す血管内治療に抵抗したプロテインS欠乏症を伴う深部静脈血栓症

    中澤 賢, 田島 廣之, 村田 智, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 秋葉 綾子, 安井 大祐, 山本 剛, 田中 啓治, 汲田 伸一郎

    静脈学   23 ( 2 )   199 - 199   2012.4

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  • 出血性胃十二指腸潰瘍に対するNBCA-TAEの循環動態への寄与と内視鏡観察による潰瘍治癒の経過

    嶺 貴彦, 村田 智, 中澤 賢, 小野澤 志郎, 上田 達夫, 山口 英宣, 秋葉 絢子, 安井 大祐, 宮内 雅人, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   71回   S327 - S327   2012.2

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  • 【静脈のIVR】下大静脈フィルター留置と回収

    村田 智, 嶺 貴彦, 中澤 賢, 上田 達夫, 秋葉 絢子, 安井 大祐, 汲田 伸一郎

    臨床放射線   57 ( 2 )   235 - 243   2012.2

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  • 腎AVMに対する血管内治療

    秋葉 絢子, 村田 智, 中澤 賢, 小野澤 志郎, 嶺 貴彦, 上田 達夫, 山口 英宣, 安井 大祐, 汲田 伸一郎, 松沢 一郎

    日本医学放射線学会学術集会抄録集   71回   S229 - S229   2012.2

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  • 肝動脈化学塞栓術におけるミリプラチンとシスプラチンの抗腫瘍効果に関する比較検討

    上田 達夫, 村田 智, 安井 大祐, 中澤 賢, 小野澤 志郎, 嶺 貴彦, 山口 英宣, 秋葉 絢子, 楢原 義之, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   71回   S243 - S243   2012.2

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  • ウサギVX2肝腫瘍に対する肝動脈化学塞栓術 シスプラチン-サスペンジョンとエマルジョンの比較

    嶺 貴彦, 村田 智, 中澤 賢, 上田 達夫, 山口 英宣, 渋川 絢子, 安井 大祐, 恩田 宗彦, 内藤 善哉, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   70回   S210 - S211   2011.2

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  • 重症門脈血栓症に対するIVR治療

    渋川 絢子, 村田 智, 中澤 賢, 嶺 貴彦, 上田 達夫, 山口 英宣, 安井 大祐, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   70回   S195 - S196   2011.2

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  • Iliocaval compression syndromeに伴う難治性腸骨静脈狭窄に対するステント留置術

    安井 大祐, 村田 智, 中澤 賢, 嶺 貴彦, 上田 達夫, 山口 英宣, 渋川 絢子, 汲田 伸一郎

    日本医学放射線学会学術集会抄録集   70回   S291 - S291   2011.2

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  • 【2010年版MRAとCTAの使い分け】骨盤・下肢動脈 PADに対するCTAとMRAの役割

    上田 達夫, 林 宏光, 村田 智, 杉崎 健一, 中澤 賢, 嶺 貴彦, 山口 英宣, 渋川 絢子, 安井 大祐, 汲田 伸一郎

    臨床画像   26 ( 10 )   1148 - 1159   2010.10

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  • 急性四肢動脈閉塞症に対する血管内治療

    上田 達夫, 村田 智, 田島 廣之, 中澤 賢, 嶺 貴彦, 山口 英宣, 渋川 絢子, 安井 大祐, 村上 隆介, 林 宏光, 汲田 伸一郎

    脈管学   50 ( Suppl. )   S240 - S240   2010.9

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  • 四肢骨盤部AVMに対する血管内治療のストラテジー

    嶺 貴彦, 村田 智, 林 宏光, 中澤 賢, 上田 達夫, 山口 英宣, 渋川 絢子, 安井 大祐, 村上 隆介, 汲田 伸一郎

    脈管学   50 ( Suppl. )   S241 - S241   2010.9

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  • 腸骨静脈血栓症に対するIVRにおけるステント留置術の有用性の検討

    安井 大祐, 村田 智, 林 宏光, 中澤 賢, 嶺 貴彦, 上田 達夫, 山口 英宣, 渋川 絢子, 村上 隆介, 汲田 伸一郎

    脈管学   50 ( Suppl. )   S173 - S173   2010.9

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