Researcher Profiles - Katsu Akifumi

写真a

Katsu Akifumi

Affiliation

Musashikosugi Hospital, Department of Urology, Assistant Professor

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Papers

Urethral caruncle causes acute urinary retention. International journal

Akifumi Katsu, Masato Yanagi, Norio Motoda, Hiroyoshi Kono, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

IJU case reports 7 ( 5 ) 368 - 370 2024.9

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INTRODUCTION: We encountered a case of urinary retention caused by a urethral caruncle. CASE PRESENTATION: An 86-year-old woman presented to our hospital with urinary retention. When the urinary bladder catheter was placed, a smooth, well-defined mass 20 mm in diameter was detected on the posterior wall of the external urethral meatus. The patient was diagnosed with urinary retention due to a urethral caruncle, and the mass was resected. The mass was pathologically compatible with a urethral caruncle. The patient could urinate postoperatively. Ultrasound test after surgery showed residual urine volume was 100 mL. CONCLUSION: Inspecting the urethral meatus is vital in the clinical examination of older women with voiding symptoms. A urethral caruncle is a rare cause of urinary retention. However, large urethral caruncles are at risk of causing urinary retention suggesting that resecting the urethral caruncles at an appropriate time is desirable.

DOI： 10.1002/iju5.12756

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Difficulty in Removing a Ureteral Stent post Childbirth due to Encrustation: A Case Report.

Masato Yanagi, Hiroyoshi Kono, Hiroyuki Muramatsu, Akifumi Katsu, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

The Kobe journal of medical sciences 70 ( 3 ) E77-E80 2024.7

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BACKGROUND: We present a case involving a pregnant woman who needed transurethral lithotripsy for ureteral stent removal because of the stent encrustation. CLINICAL CASE: A 34-year-old woman was diagnosed with calculous pyelonephritis, and a double-loop ureteral stent was placed in her right ureter, after which the pyelonephritis resolved. One week after her delivery, we attempted to remove the ureteral stent; however, the encrustation of the proximal and distal coils made it impossible. We then crushed the encrustation by transurethral lithotripsy and removed the ureteral stent successfully. The encrustation component was calcium phosphate, and the urinary pH during pregnancy and after delivery was 7.5. CONCLUSION: Even in pregnant patients, patients placed ureteral stents for obstructive pyelonephritis with high urine pH might need to be replaced in the short term due to concerns regarding phosphate encrustation.

DOI： 10.24546/0100490328

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Preoperative oral treatment with cyclooxygenase-2 inhibitor for cystitis glandularis. International journal

Masato Yanagi, Norio Motoda, Akifumi Katsu, Hiroyoshi Kono, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

IJU case reports 7 ( 4 ) 297 - 300 2024.7

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INTRODUCTION: A previous report has shown that cyclooxygenase-2 inhibitors can prevent the recurrence of cystitis glandularis postoperatively. Herein, we present a case of cystitis glandularis in which the tumor volume was markedly reduced by preoperative oral administration of a cyclooxygenase-2 inhibitor. CASE PRESENTATION: A 45-year-old man with voiding difficulty and lower abdominal pain during urination was referred to our hospital. Cystoscopy revealed multiple cystitis glandularis-like edematous masses on the trigone and the neck of the bladder, completely involving the bilateral ureteral orifices. Cyclooxygenase-2 inhibitor was orally administered at the patient's request. Six weeks later, the tumor volume was markedly reduced, bilateral ureteral orifices were identified, and the voiding difficulty and pain on urination disappeared. Complete transurethral resection of the residual tumor was performed, and the pathological diagnosis was intestinal-type cystitis glandularis. CONCLUSION: Cyclooxygenase-2 inhibition can be considered a useful therapeutic strategy for cystitis glandularis.

DOI： 10.1002/iju5.12728

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Preoperative rapid growth of inferior vena cava tumor thrombus in renal cell carcinoma. International journal

Akifumi Katsu, Masato Yanagi, Masato Yoshioka, Norio Motoda, Hideyuki Takata, Hiroyoshi Kono, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

IJU case reports 7 ( 3 ) 230 - 233 2024.5

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INTRODUCTION: We present the case of a rapidly growing inferior vena cava tumor thrombus in renal cell carcinoma. CASE PRESENTATION: We present a case of a 66-year-old woman with right renal cell carcinoma with a tumor thrombus extending 2 cm into the inferior vena cava on an initial Imaging. Radical surgery was performed 6 weeks after the first visit. Intraoperatively, the tumor thrombus was confirmed to have grown near the diaphragm. The tumor was resected using an inferior vena cava clamping just below the diaphragm. The tumor thrombus and renal cell carcinoma were completely removed. There was no recurrence 6 months postoperatively. CONCLUSION: Inferior vena cava tumor thrombus in renal cell carcinoma can grow in a short period, suggesting that preoperative imaging evaluation at the appropriate time is important. Once inferior vena cava tumor thrombus of renal cell carcinoma occurs, surgery should not be delayed unless there is an urgent reason.

DOI： 10.1002/iju5.12709

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Usefulness of hand-assisted retroperitoneal laparoscopic radical nephrectomy for extreme obese patients -a case report.

Masato Yanagi, Tsutomu Hamasaki, Akifumi Katsu, Hiroyoshi Kono, Ryoji Kimata, Taiji Nishimura, Yukihiro Kondo

The journal of medical investigation : JMI 71 ( 1.2 ) 187 - 190 2024

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We report a case of retroperitoneal laparoscopic radical nephrectomy (LRN) in which the addition of a hand port was necessary and effective. A 52-year-old man with obesity (BMI 40.6 kg/m2) was diagnosed with a 52-mm left renal cell carcinoma (cT1bN0M0). To avoid thick subcutaneous and visceral fat in the abdomen, we selected LRN using a retroperitoneal approach with four ports in the kidney position. During surgery, a large amount of flank pad and perirenal fat prevented us from securing a sufficient surgical field through traction of the kidney with a retractor. A pure laparoscopic procedure was not feasible;therefore, we added a hand port. Subsequently, we removed the flank pad from the hand port and secured the surgical field by tracing the kidney manually. Finally, hand-assisted LRN was completed without an open conversion. In retroperitoneal LRN, we rarely encounter patients for whom a pure laparoscopic procedure is not feasible because of the large amount of flank pad or perirenal fat. It is important to preoperatively confirm not only the BMI but also the amount of flank pad and perirenal fat on imaging. Hand-assisted LRN via the retroperitoneal approach can be safely performed even in extremely obese patients. J. Med. Invest. 71 : 187-190, February, 2024.

DOI： 10.2152/jmi.71.187

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Obstructive azoospermia caused by epididymis injury with testicle rupture on the other side. International journal

Takayuki Ueda, Masato Yanagi, Akifumi Katsu, Hiroyoshi Kono, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo

Acute medicine & surgery 11 ( 1 ) e919 2024

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BACKGROUND: Epididymal injuries without ipsilateral injuries of the testicles are rare. We report a case of a solitary right epididymal injury complicated by left testicular rupture. CASE PRESENTATION: A 21-year-old man experienced scrotal trauma caused by a motorcycle accident. Bilateral swelling and tenderness of the scrotum were observed. Ultrasonography and computed tomography revealed a ruptured left testicle; therefore, surgery was performed. During surgery, the left testicle was excised because it was completely ruptured, and the right testicle and epididymis were evaluated to identify the cause of swelling of the right scrotum. The right testis was not injured; however, the right epididymis was lacerated. Subsequently, the lacerated right epididymis was repaired using sutures. A semen analysis performed at 1, 4, and 7 months after surgery revealed the absence of sperm in the semen. CONCLUSION: Epididymal injuries should be considered as differential diagnoses for scrotal trauma.

DOI： 10.1002/ams2.919

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A case of marked rectal stenosis due to Douglas' pouch metastasis of renal pelvic carcinoma successfully treated with salvage enfortumab vedotin: correlation between serum KL-6 levels and tumor response. International journal

Jun Akatsuka, Go Kimura, Akifumi Katsu, Hiroya Hasegawa, Hikaru Mikami, Masato Yanagi, Yuki Endo, Hayato Takeda, Yuka Toyama, Yukihiro Kondo

IJU case reports 6 ( 6 ) 449 - 453 2023.11

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INTRODUCTION: We report a rare case of marked rectal stenosis due to Douglas' pouch metastasis of renal pelvic urothelial carcinoma successfully treated with enfortumab vedotin. CASE PRESENTATION: A 77-year-old female presented with difficulty in defecation and abdominal distension. She had received two courses of cisplatin plus gemcitabine followed by four courses of maintenance avelumab for postoperative lymph node metastasis of renal pelvic urothelial carcinoma. KL-6 levels were elevated, and a computed tomography scan revealed an irregularly shaped large mass occupying Douglas' pouch, with marked rectal stenosis. Metastatic urothelial carcinoma was pathologically diagnosed, and enfortumab vedotin was initiated after colostomy. After 12 courses of enfortumab vedotin, metastatic lesions showed marked shrinkage and KL-6 levels decreased. CONCLUSION: Enfortumab vedotin elicited a remarkable response in treating rectal stenosis due to metastasis of renal pelvic urothelial carcinoma in Douglas' pouch. Furthermore, serum KL-6 levels were correlated with the severity of metastatic urothelial carcinoma.

DOI： 10.1002/iju5.12645

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Differential diagnosis and prognosis of small renal masses: association with collateral vessels detected using contrast-enhanced computed tomography. International journal

Masato Yanagi, Tomonari Kiriyama, Jun Akatsuka, Yuki Endo, Hayato Takeda, Akifumi Katsu, Yuichiro Honda, Kyota Suzuki, Yoshihiro Nishikawa, Shunsuke Ikuma, Hikaru Mikami, Yuka Toyama, Go Kimura, Yukihiro Kondo

BMC cancer 22 ( 1 ) 856 - 856 2022.8

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BACKGROUND: Active surveillance (AS) is one of the treatment methods for patients with small renal masses (SRMs; < 4 cm), including renal cell carcinomas (RCCs). However, some small RCCs may exhibit aggressive neoplastic behaviors and metastasize. Little is known about imaging biomarkers capable of identifying potentially aggressive small RCCs. Contrast-enhanced computed tomography (CECT) often detects collateral vessels arising from neoplastic angiogenesis in RCCs. Therefore, this study aimed to evaluate the association between SRM differential diagnoses and prognoses, and the detection of collateral vessels using CECT. METHODS: A total of 130 consecutive patients with pathologically confirmed non-metastatic SRMs (fat-poor angiomyolipomas [fpAMLs; n = 7] and RCCs [n = 123]) were retrospectively enrolled. Between 2011 and 2019, SRM diagnoses in these patients were confirmed after biopsy or surgical resection. All RCCs were surgically resected. Regardless of diameter, a collateral vessel (CV) was defined as any blood vessel connecting the tumor from around the kidney using CECT. First, we analyzed the role of CV-detection in differentiating between fpAML and RCC. Then, we evaluated the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of RCC diagnosis based on CV-detection using CECT. We also assessed the prognostic value of CV-detection using the Fisher exact test, and Kaplan-Meier method and the log-rank test. RESULTS: The sensitivity, specificity, PPV, NPV, and accuracy of CV-detection for the diagnosis of small RCCs was 48.5, 45.5, 100, 100, and 9.5% respectively. Five of 123 (4.1%) patients with RCC experienced recurrence. CV-detection using CECT was the only significant factor associated with recurrence (p = 0.0177). Recurrence-free survival (RFS) was significantly lower in patients with CV compared with in those without CV (5-year RFS 92.4% versus 100%, respectively; p = 0.005). In addition, critical review of the CT images revealed the CVs to be continuous with the venous vessels around the kidney. CONCLUSIONS: The detection of CVs using CECT is useful for differentiating between small fpAMLs and RCCs. CV-detection may also be applied as a predictive parameter for small RCCs prone to recurrence after surgical resection. Moreover, AS could be suitable for small RCCs without CVs.

DOI： 10.1186/s12885-022-09971-w

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Misc.

高度肥満症例に対するハンドアシスト併用腹腔鏡下腎摘除術の有用性

柳雅人, 濱崎務, 鈴村健太, 勝彬史, 河野弘圭, 木全亮二, 西村泰司, 近藤幸尋

泌尿器外科 37 ( 臨増 ) 723 - 723 2024.6

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尿閉をきたした巨大尿道カルンクルの1例

勝彬史, 柳雅人, 河野弘圭, 木全亮二, 濱崎務, 近藤幸尋

泌尿器外科 37 ( 臨増 ) 774 - 774 2024.6

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膀胱皮膚瘻を形成した膀胱結石の1例

鈴木喬大, 木村剛, 赤塚純, 遠藤勇気, 武田隼人, 戸山友香, 近藤幸尋, 三神晃, 柳雅人, 井熊俊介, 西川佳宏, 勝彬史, 本田悠一郎

泌尿器外科 36 ( 10 ) 1164 - 1164 2023.10

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著明な直腸狭窄を来した腎盂癌術後再発へのエンホルツマブベドチン治療でKL.6が病勢マーカーとなった1例

勝彬史, 木村剛, 赤塚純, 谷内真美, 長谷川裕也, 三神晃, 柳雅人, 遠藤勇気, 武田隼人, 戸山友香, 近藤幸尋

泌尿器外科 36 ( 10 ) 1166 - 1166 2023.10

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Nivolumab+ipilimumab併用療法が奏功した著明な貧血を伴う転移性腎細胞癌の一例

本田悠一朗, 木村剛, 武田隼人, 鈴木喬大, 勝彬史, 西川佳宏, 井熊俊介, 三神晃, 柳雅人, 遠藤勇気, 赤塚純, 戸山友香, 近藤幸尋

泌尿器外科 36 ( 10 ) 1162 - 1162 2023.10

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腎癌に対する後腹膜鏡下根治敵陣摘除術における手術時間の延長因子

柳雅人, 濱崎務, 木全亮二, 赤塚純, 遠藤勇気, 武田隼人, 谷内真美, 勝彬史, 長谷川裕也, 三神晃, 高橋亮, 戸山友香, 木村剛, 西村泰司, 近藤幸尋

泌尿器外科 36 ( 臨増 ) 882 - 882 2023.8

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尿閉を契機として発見された腎細胞癌前立腺転移の1例

井熊俊介, 木村剛, 本田悠一郎, 鈴木喬太, 勝彬史, 西川佳宏, 三神晃, 柳雅人, 赤塚純, 遠藤勇気, 武田隼人, 戸山友香, 近藤幸尋

腎癌研究会会報 ( 53 ) 108 - 108 2023.7

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Nivolumab+Ipilimumab投与後にdelayed cytoreductive nephrectomyやmetastasectomyを施行した症例の臨床病理学的検討

武田隼人, 木村剛, 勝彬史, 三神晃, 柳雅人, 赤塚純, 遠藤勇気, 戸山友香, 近藤幸尋

腎癌研究会会報 ( 53 ) 93 - 93 2023.7

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腫瘍随伴症候群としての著明な貧血を認めた転移性腎細胞癌の1例

勝彬史, 木村剛, 赤塚純, 谷内真美, 長谷川裕也, 三神晃, 柳雅人, 遠藤勇気, 武田隼人, 戸山友香, 近藤幸尋

腎癌研究会会報 ( 53 ) 106 - 106 2023.7

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転移性腎癌におけるLDHアイソザイムの予後との関連(Association of serum lactate dehydrogenase(LDH) isozyme with prognosis of patients with metastatic clear cell renal cell carcinoma(mCRCC))

武田隼人, 木村剛, 谷内真美, 勝彬史, 長谷川裕也, 三神晃, 柳雅人, 赤塚純, 遠藤勇気, 戸山友香, 近藤幸尋

日本泌尿器科学会総会 110回 PP64 - 07 2023.4

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系統的14ヶ所18本生検を受ける初回生検症例におけるcognitive MRI標的生検の領域別診断能(Comparison of diagnostic performance of cognitive MRI targeted biopsy in three anatomical zones of the prostate)

戸山友香, 木村剛, 赤塚純, 香山重軌, 遠藤勇気, 武田隼人, 高橋亮, 柳雅人, 三神晃, 長谷川裕也, 勝彬史, 谷内真美, 近藤幸尋

日本泌尿器科学会総会 110回 OP02 - 02 2023.4

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小径腎癌の造影CTにおける側副血行路の存在と根治術後の予後との関連(Collateral vessel on contrast-enhanced computed tomography is associated with the poor prognosis for small renal cell carcinoma after radical surgery)

柳雅人, 桐山智成, 赤塚純, 遠藤勇気, 武田隼人, 谷内真美, 勝彬史, 長谷川裕也, 三神晃, 戸山友香, 木村剛, 西村泰司, 近藤幸尋

日本泌尿器科学会総会 110回 OP39 - 05 2023.4

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尿細胞診による術前膀胱癌亜型予測に関する検討(Can urine cytology predict variants of bladder cancer?)

三神晃, 木村剛, 谷内真美, 勝彬史, 柳雅人, 武田隼人, 赤塚純, 遠藤勇気, 戸山友香, 近藤幸尋

日本泌尿器科学会総会 110回 PP15 - 04 2023.4

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当院における転移性尿路上皮癌に対するenfortumab-vedotin療法についての初期報告(Efficacy and Safety of enfortumab-vedotin in patient with metastatic urothelial carcinoma: an initial report)

遠藤勇気, 木村剛, 赤塚純, 武田隼人, 長谷川裕也, 三神晃, 柳雅人, 戸山友香, 勝彬史, 舩門良太, 谷内真美, 近藤幸尋

日本泌尿器科学会総会 110回 PP21 - 07 2023.4

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去勢抵抗性前立腺癌患者に対するBRCA遺伝子検査とOlaparib投与症例の検討(Status of genomic profiling test and olaparib treatment for patients with metastatic castration-resistant prostate cancer in our institution)

赤塚純, 木村剛, 谷内真美, 勝彬史, 長谷川裕也, 三神晃, 柳雅人, 遠藤勇気, 武田隼人, 高橋亮, 戸山友香, 近藤幸尋

日本泌尿器科学会総会 110回 PP45 - 07 2023.4

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当院での前立腺神経内分泌癌症例の臨床病理学的特徴と予後(Clinicopathological features and prognosis of neuroendocrine prostate carcinoma in our hospital)

長谷川裕也, 木村剛, 柳雅人, 遠藤勇気, 谷内真美, 勝彬史, 三神晃, 赤塚純, 武田隼人, 戸山友香, 近藤幸尋

日本泌尿器科学会総会 110回 PP59 - 08 2023.4

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尿閉を契機として発見された腎細胞癌前立腺転移の1例(A case of prostate metastasis originating from renal cell carcinoma discovered by urinary retention)

井熊俊介, 木村剛, 勝彬史, 西川佳宏, 三神晃, 柳雅人, 遠藤勇気, 武田隼人, 赤塚純, 戸山友香, 近藤幸尋

日本泌尿器科学会総会 110回 PP63 - 06 2023.4

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転移性膀胱癌に対する1次プラチナ併用化学療法2コース後のアベルマブ療法の初期報告

遠藤勇気, 木村剛, 赤塚純, 武田隼人, 三神晃, 長谷川裕也, 柳雅人, 谷内真美, 勝彬史, 戸山友香, 近藤幸尋

日本癌治療学会学術集会抄録集 60回 P88 - 6 2022.10

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臨床病理学的特徴と予後前立腺神経内分泌癌

長谷川裕也, 木村剛, 柳雅人, 遠藤勇気, 谷内真美, 勝彬史, 三神晃, 赤塚純, 武田隼人, 戸山由香, 近藤幸尋

日本癌治療学会学術集会抄録集 60回 O73 - 7 2022.10

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系統的14ヶ所18本生検を受ける初回生検症例におけるcognitive MRI標的生検の診断能

戸山友香, 木村剛, 赤塚純, 遠藤勇気, 武田隼人, 香山重軌, 井熊俊介, 西川佳宏, 勝彬史, 鈴木喬大, 本田悠一朗, 船戸良太, 柳雅人, 三神晃, 近藤幸尋

日本癌治療学会学術集会抄録集 60回 P49 - 4 2022.10

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Nivolumab+Ipilimumab後delayed CNやmetastasectomyを施行した症例の臨床病理学的検討

武田隼人, 木村剛, 谷内真美, 勝彬史, 長谷川裕也, 三神晃, 柳雅人, 赤塚純, 遠藤勇気, 戸山友香, 近藤幸尋

日本癌治療学会学術集会抄録集 60回 P51 - 6 2022.10

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術前に後腹膜腫瘍との鑑別が困難であった膀胱原発平滑筋腫の一例

谷内真美, 木村剛, 柳雅人, 遠藤勇気, 長谷川裕也, 勝彬史, 三神晃, 赤塚純, 武田隼人, 戸山友香, 近藤幸尋

日本癌治療学会学術集会抄録集 60回 P52 - 4 2022.10

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Nivolumab+Ipilimumab投与後にdelayed cytoreductive nephrectomyやmetastasectomyを施行した症例の臨床病理学的検討

武田隼人, 木村剛, 勝彬史, 三神晃, 柳雅人, 赤塚純, 遠藤勇気, 戸山友香, 近藤幸尋

腎癌研究会会報 ( 52 ) 40 - 40 2022.7

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尿膜管開存症を背景とした間欠的な臍部からの排尿を初発症状とした前立腺癌の1例

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Language：Japanese Publisher：医学図書出版(株)

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Language：Japanese Publisher：(一社)腎癌研究会

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腎癌研究会会報 ( 52 ) 55 - 55 2022.7

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Language：Japanese Publisher：(一社)腎癌研究会

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当科で経験した副腎出血の3例

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日本泌尿器科学会総会 109回 OP60 - 02 2021.12

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Language：Japanese Publisher：(一社)日本泌尿器科学会総会事務局

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日本泌尿器科学会総会 109回 PP53 - 05 2021.12

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日本癌治療学会学術集会抄録集 59回 O17 - 1 2021.10

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Language：English Publisher：(一社)日本癌治療学会

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日本癌治療学会学術集会抄録集 59回 O18 - 6 2021.10

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日本癌治療学会学術集会抄録集 59回 O60 - 2 2021.10

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