Affiliation
Faculty of Medicine, Department of Medicine, Research Laboratory for Magnetic Resonance, Assistant Professor
Title
Assistant Professor
External link
Okihara Kaori
Degree
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農学修士（山口大学）
Education
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山口大学大学院 農学研究科 農芸化学専攻
1996.3
Research History
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Nippon Medical School
2024.4
Professional Memberships
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日本磁気共鳴医学会
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日本核磁気共鳴学会
Papers
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Proton Nuclear Magnetic Resonance With Time-Frequency Analysis: A Potential Diagnostic Approach for Keloids. International journal
Guangpeng Xia, Teruyuki Dohi, Keiko Hirakawa, Kaori Okihara, Ei Hiruma, Shun Minagawa, Mohamed Abdelhakim, Tomoko Konta, Nikki Terashi, Yoshimasa Kanawaku, Rei Ogawa
International wound journal 23 ( 3 ) e70865 2026.3
Research Projects
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最新の核磁気共鳴(ＮＭＲ)分析技術を用いた革新的な溺水吸引診断法への応用の試み
Grant number：24K22213 2024.6 - 2027.3
日本学術振興会 科学研究費助成事業 挑戦的研究(萌芽)
崔 范来, 平川 慶子, 市川 実咲, 金涌 佳雅, 由井 奏子, 沖原 香
Grant amount：\6370000 （ Direct Cost: \4900000 、 Indirect Cost：\1470000 ）
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複数のNMR分析技術による死後髄液からの同時複合的な法医診断法の開発
Grant number：24K13556 2024.4 - 2027.3
日本学術振興会 科学研究費助成事業 基盤研究(C)
金涌 佳雅, 平川 慶子, 市川 実咲, 崔 范来, 沖原 香, 由井 奏子
Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）
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Development of a method for determining the cause of death from postmortem body fluid samples using NMR modal analysis
Grant number：21K19676 2021.7 - 2025.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory)
Ichikawa Misaki
Grant amount：\6370000 （ Direct Cost: \4900000 、 Indirect Cost：\1470000 ）
Postmortem cerebrospinal fluid collected during a forensic autopsy was subjected to nuclear magnetic resonance (NMR) measurement, followed by time-frequency analysis. The resulting spectrogram data were analysed using PLS-DA to verify the ability to identify or detect the presence of cranial trauma, pathological conditions, and postmortem interval. The results indicated the possibility of detecting the presence of cranial trauma and other factors derived from postmortem cerebrospinal fluid.Nevertheless, the spectrogram data obtained from this experiment was deemed to contain various biomedical information present in postmortem cerebrospinal fluid. It was therefore recognised that further research was necessary to develop a testing method that could be immediately utilised in forensic practice, given that the data may be influenced by drugs or other factors.
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Research on the application of qNMR method to forensic toxicological analysis
Grant number：21K10534 2021.4 - 2025.3
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Kanawaku Yoshimasa
Grant amount：\4290000 （ Direct Cost: \3300000 、 Indirect Cost：\990000 ）
A series of experiments were conducted using the qNMR method to ascertain the concentration of ascorbic acid solution. Ascorbic acid is a human endogenous substance and one of the components detected in blood. A comparative analysis was performed using high-performance liquid chromatography (HPLC) on the same sample. Following the optimisation of the measurement conditions for the qNMR method, it was determined that the NMR spectra of the ascorbic acid solution samples were obtained without incident under the prevailing measurement conditions.No impurity peaks that could potentially interfere with quantitative calculations were identified in the spectra. The correlation between the ascorbic acid concentrations quantified by qNMR and HPLC methods was found to be extremely good. In serum samples characterised by elevated levels of mixed components, it was determined that the successful extraction of peaks necessitates the application of expertise.