Updated on 2026/03/10

写真a

 
AMANO Yasuo
 
Affiliation
Nippon Medical School Hospital, Department of Radiology, Clinical Professor
Title
Clinical Professor
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Degree

  • 博士(医学) ( 日本医科大学 )

Research Interests

  • Cardiovascular MRI

Education

Research History

  • Department of Radiology, Nihon University

    2016.4

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  • Department of Radiology, Nihon University

    2016.4

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Papers

  • Relationship between measurement errors in myocardial T1 mapping and heart rate. Reviewed

    Amano Y, Omori Y, Yanagisawa F, Ando C, Shinoda N, Suzuki Y, Yamamoto H, Matsumoto N

    Magnetic Resonance in Medical Sciences   19   345 - 350   2020

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  • Measurement of Turbulent Kinetic Energy in Hypertrophic Cardiomyopathy Using Triple-velocity Encoding 4D Flow MR Imaging.

    Kotomi Iwata, Tetsuro Sekine, Junya Matsuda, Masaki Tachi, Yoichi Imori, Yasuo Amano, Takahiro Ando, Makoto Obara, Gerard Crelier, Masashi Ogawa, Hitoshi Takano, Shinichiro Kumita

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   2022.12

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    PURPOSE: The turbulent kinetic energy (TKE) estimation based on 4D flow MRI has been currently developed and can be used to estimate the pressure gradient. The objective of this study was to validate the clinical value of 4D flow-based TKE measurement in patients with hypertrophic cardiomyopathy (HCM). METHODS: From April 2018 to March 2019, we recruited 28 patients with HCM. Based on echocardiography, they were divided into obstructed HCM (HOCM) and non-obstructed HCM (HNCM). Triple-velocity encoding 4D flow MRI was performed. The volume-of-interest from the left ventricle to the aortic arch was drawn semi-automatically. We defined peak turbulent kinetic energy (TKEpeak) as the highest TKE phase in all cardiac phases. RESULTS: TKEpeak was significantly higher in HOCM than in HNCM (14.83 ± 3.91 vs. 7.11 ± 3.60 mJ, P < 0.001). TKEpeak was significantly higher in patients with systolic anterior movement (SAM) than in those without SAM (15.60 ± 3.96 vs. 7.44 ± 3.29 mJ, P < 0.001). Left ventricular (LV) mass increased proportionally with TKEpeak (P = 0.012, r = 0.466). When only the asymptomatic patients were extracted, a stronger correlation was observed (P = 0.001, r = 0.842). CONCLUSION: TKE measurement based on 4D flow MRI can detect the flow alteration induced by systolic flow jet and LV outflow tract geometry, such as SAM in patients with HOCM. The elevated TKE is correlated with increasing LV mass. This indicates that increasing cardiac load, by pressure loss due to turbulence, induces progression of LV hypertrophy, which leads to a worse prognosis.

    DOI: 10.2463/mrms.mp.2022-0051

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  • Localization of Late Gadolinium Enhancement and Its Association with Ventricular Tachycardia in Patients with Cardiac Sarcoidosis

    Kenji Yodogawa, Yoshimitsu Fukushima, Masaki Tachi, Yuhi Fujimoto, Kanako Hagiwara, Eiichiro Oka, Hiroshi Hayashi, Hiroshige Murata, Teppei Yamamoto, Yu-Ki Iwasaki, Yasuo Amano, Shin-ichiro Kumita, Wataru Shimizu

    INTERNATIONAL HEART JOURNAL   63 ( 2 )   235 - 240   2022.3

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    DOI: 10.1536/ihj.21-635

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  • Relationship between myocardial T1 and T2 values and cardiac function and 1-year outcome in male patients with chronic kidney disease. Reviewed

    Omori Y, Amano Y, Yanagisawa F, Suzuki Y, Ando C, Yamamoto H, Matsumoto N.

    日本大学医学雑誌   81   29 - 34   2022

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  • Detection of myocardial tissue alterations in hypertrophic cardiomyopathy using texture analysis of T2-weighted STIR MRI. Reviewed International journal

    87.Amano Y, Yanagiswa F, Omori Y, SuzukiY, Ando C, Yamamoto H, Matsumoto N.

    Journal of Computer Assisted Tomography   44   341 - 345   2020

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  • Distribution of medial calcification and luminal stenosis in symptomatic patients with hemodialysis and peripheral artery disease using 3D computed tomography angiography. Iranian Journal of Radiology 2020; 17: e98855 Reviewed International journal

    Amano Y, Yanagisawa F, Takagi R, Harasawa S, Omori Y, Matsumoto N.

    Iranian Journal of Radiology   17   e98855   2020

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  • Four-Dimensional Flow MRI Analysis of Cerebral Blood Flow Before and After High-Flow Extracranial-Intracranial Bypass Surgery With Internal Carotid Artery Ligation. Reviewed

    Orita E, Murai Y, Sekine T, Takagi R, Amano Y, Ando T, Iwata K, Obara M, Kumita S

    Neurosurgery   85 ( 1 )   58 - 64   2019.7

  • Relation of 4D flow MRI of ophthalmic artery to cerebral vascular reactivity estimated with SPECT in patients with internal carotid artery occlusion Reviewed International journal

    Sekine T, Takagi R, Amano Y, Murai Y, Orita E, Fukushima Y, Matsumura Y, Kumita S

    Magnetic Resonance in Medical Sciences   17   13 - 20   2018.1

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  • 4D Flow MR Imaging of Ophthalmic Artery Flow in Patients with Internal Carotid Artery Stenosis. Reviewed

    Sekine T, Takagi R, Amano Y, Murai Y, Orita E, Fukushima Y, Matsumura Y, Kumita SI

    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   17 ( 1 )   13 - 20   2018.1

  • Vaginal tumor-vesical fistula detected by dynamic fluorodeoxyglucose-positron emission tomography/computed tomography: a case report Reviewed International journal

    Ishibashi N, Maebayashi T, Aizawa T, Sakaguchi M, Amano Y.

    Clinical Imaging   46   113 - 115   2017.1

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  • Myocardial T2 mapping in patients with hypertrophic cardiomyopathy Reviewed

    Yasuo Amano, Fumi Yanagisawa, Masaki Tachi, Hidenobu Hashimoto, Shogo Imai, Shinichiro Kumita

    Journal of Computer Assisted Tomography   41 ( 3 )   344 - 348   2017

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Lippincott Williams and Wilkins  

    DOI: 10.1097/RCT.0000000000000521

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  • Superiority of the extracellular volume fraction over the myocardial T1 value for the assessment of myocardial fibrosis in patients with non-ischemic cardiomyopathy Reviewed

    Keisuke Inui, Masaki Tachi, Tsunenori Saito, Yoshiaki Kubota, Koji Murai, Koji Kato, Hitoshi Takano, Yasuo Amano, Kuniya Asai, Wataru Shimizu

    MAGNETIC RESONANCE IMAGING   34 ( 8 )   1141 - 1145   2016.10

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    DOI: 10.1016/j.mri.2016.05.008

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  • 4D Flow MRI assessment of extracranial-intracranial bypass: qualitative and quantitative evaluation of the hemodynamics. Reviewed

    Sekine T, Takagi R, Amano Y, Murai Y, Orita E, Matsumura Y, Kumita S.

    Neuroradiology   58 ( 3 )   237 - 244   2016.3

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    DOI: 10.1007/s00234-015-1626-1

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  • Contrast-enhanced steady-state free precession in the assessment of hypertrophic obstructive cardiomyopathy after alcohol septal ablation.

    Amano Y, Yamada F, Kitamura M, Tachi M, Mine K, Kumita S, Takayama M

    Magnetic Resonance in Medical Sciences   15 ( 1 )   130 - 136   2016.2

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    DOI: 10.2463/mrms.2015-0037

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  • Distribution and clinical significance of high signal intensity of the myocardium on T2-weighted images in 2 phenotypes of hypertrophic cardiomyopathy

    Amano Y, Aita K, Yamada F, Kitamura M, Kumita S

    Journal of Computer Assisted Tomography   39 ( 6 )   951 - 955   2015.11

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    DOI: 10.1097/RCT.0000000000000296

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  • Magnetic resonance imaging of microvascular obstruction in hypertrophic obstructive cardiomyopathy after percutaneous transluminal septal myocardial ablation

    Amano Y, Kitamura M, Yamada F, Aita K, Takayama M, Tachi M, Kumita S

    Acta Radiologica   56 ( 11 )   1323 - 1328   2015.11

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    DOI: 10.1177/0284185114559871

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  • Pseudonormal corticomedullary differentiation of the kidney assessed by T1-weighted MRI in chronic kidney disease patients with cirrhosis

    Yamada F, Amano Y, Hidaka F, Fukushima Y, Kumita S

    Magnetic Resonance in Medical Sciences   14 ( 3 )   165 - 171   2015.6

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    DOI: 10.2463/mrms.2014-0044

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  • Myocardial fibrosis evaluated by Look-Locker and late gadolinium enhancement magnetic resonance imaging in apical hypertrophic cardiomyopathy: association with ventricular tachyarrhythmia and risk factors

    Amano Y, Takeda M, Tachi M, Kitamura M, Kumita S

    Journal of Magnetic Resonance Imaging   40 ( 2 )   407 - 412   2014.8

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    DOI: 10.1002/jmri.24357

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  • Delayed enhancement magnetic resonance imaging in hypertrophic cardiomyopathy with basal septal hypertrophy and preserved ejection fraction: relationship with ventricular tachyarrhythmia

    Amano Y, Kitamura M, Tachi M, Takeda M, Mizuno K, Kumita S

    Journal of Computer Assisted Tomography   38 ( 1 )   67 - 71   2014.1

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    DOI: 10.1097/RCT.0b013e3182a2fb01

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  • Volume Change and Liver Parenchymal Signal Intensity in Gd-EOB-DTPA-Enhanced Magnetic Resonance Imaging after Portal Vein Embolization prior to Hepatectomy Reviewed

    Ayako Akiba, Satoru Murata, Takahiko Mine, Shiro Onozawa, Tetsuro Sekine, Yasuo Amano, Youichi Kawano, Eiji Uchida, Shin-ichiro Kumita

    BIOMED RESEARCH INTERNATIONAL   2014   684754   2014

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    DOI: 10.1155/2014/684754

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  • Evaluation of non-scarred myocardial T1 value using contrast-enhanced Look-Locker cardiac MRI and its relationship to cardiac function in dilated cardiomyopathy: comparison of 1.5T and 3.0T MRI

    Tachi M, Amano Y, Kobayashi Y, Mizuno K, Kumita S

    Journal of Magnetic Resonance Imaging   38 ( 6 )   1395 - 1401   2013.12

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    DOI: 10.1002/jmri.24131

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  • MRI differentiation of cardiomyopathy showing left ventricular hypertrophy and heart failure: differentiation between cardiac amyloidosis, hypertrophic cardiomyopathy, and hypertensive heart disease Reviewed

    Minako Takeda, Yasuo Amano, Masaki Tachi, Hitomi Tani, Kyoichi Mizuno, Shinichiro Kumita

    JAPANESE JOURNAL OF RADIOLOGY   31 ( 10 )   693 - 700   2013.10

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    DOI: 10.1007/s11604-013-0238-0

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  • Underestimation of the ejection fraction using the quantitative gated SPECT for patients with myocardial hypertrophy Reviewed

    Hidenori Yamaguchi, Masahiro Toba, Yasuo Amano, Keiichi Ishihara, Kyoichi Mizuno, Shin-ichiro Kumita

    ANNALS OF NUCLEAR MEDICINE   27 ( 6 )   502 - 507   2013.7

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    DOI: 10.1007/s12149-013-0713-9

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  • Comparison of perfusion-metabolism mismatch in 99mTc-MIBI and 123I-BMIPP scintigraphy with cardiac magnetic resonance in patients with dilated cardiomyopathy. Reviewed

    Yoshida A, Takano H, Asai K, Yasutake M, Amano Y, Kumita S, Shimizu W, Mizuno K

    Journal of cardiac failure   19 ( 7 )   445 - 453   2013.7

  • Analysis of ischemic cerebral lesions using 3.0-T diffusion-weighted imaging and magnetic resonance angiography after revascularization surgery for ischemic disease Reviewed

    Yasuo Murai, Takayuki Mizunari, Ryo Takagi, Yasuo Amano, Sunao Mizumura, Yuichi Komaba, Seiji Okubo, Shiro Kobayashi, Akira Teramoto

    CLINICAL NEUROLOGY AND NEUROSURGERY   115 ( 7 )   1063 - 1070   2013.7

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    DOI: 10.1016/j.clineuro.2012.10.021

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  • Three-dimensional Look-Locker MRI for evaluation of postcontrast myocardial and blood T1-values: comparison with two-dimensional Look-Locker and late gadolinium enhancement MRI Reviewed

    Amano Y, Tachi M, Kumita S

    Acta Radiologica   54 ( 1 )   8 - 13   2013.2

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    DOI: 10.1258/ar.2012.120378

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  • Four-dimensional flow magnetic resonance imaging assessment of hemodynamics in patients after extracranial-intracranial bypass surgery. Reviewed

    Sekine T, Amano Y, Takagi R, Matsumura Y, Suzuki Y, Murai Y, Kumita S

    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   80 ( 1 )   2 - 3   2013

  • MRI classification of asymmetric septal hypertrophic cardiomyopathy and its relation to the presence of risk factors

    Yasuo Amano, Mitsunobu Kitamura, Morimasa Takayama, Masaki Tachi, Shinichiro Kumita

    INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING   28 ( 8 )   2019 - 2025   2012.12

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    DOI: 10.1007/s10554-012-0034-4

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  • T2-weighted and delayed enhancement MRI of eosinophilic myocarditis: relationship with clinical phases and global cardiac function Reviewed

    Hitomi Tani, Yasuo Amano, Masaki Tachi, Tadashi Machida, Kyoichi Mizuno, Shinichiro Kumita

    JAPANESE JOURNAL OF RADIOLOGY   30 ( 10 )   824 - 831   2012.12

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    DOI: 10.1007/s11604-012-0130-3

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  • CT, MRI, and PET findings of gastric schwannoma Reviewed

    Minako Takeda, Yasuo Amano, Tadashi Machida, Shunji Kato, Zenya Naito, Shinichiro Kumita

    JAPANESE JOURNAL OF RADIOLOGY   30 ( 7 )   602 - 605   2012.8

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    DOI: 10.1007/s11604-012-0093-4

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  • Simultaneous assessment of myocardial scar and coronary arteries using navigator-gated three-dimensional fat-suppressed delayed-enhancement MRI at 3.0 T: a technical feasibility study

    Yasuo Amano, Tomonari Kiriyama, Yasuhiro Kobayashi, Masaki Tachi, Yoshio Matsumura, Shinichiro Kumita

    Journal of Computer Assisted Tomography   36 ( 1 )   72 - 76   2012.1

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    DOI: 10.1097/RCT.0b013e3182455cca

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  • Comparison of Epirubicin-Iodized Oil Suspension and Emulsion for Transcatheter Arterial Chemoembolization in VX2 Tumor

    Tatsuo Ueda, Satoru Murata, Takahiko Mine, Shiro Onozawa, Munehiko Onda, Zenya Naito, Yasuo Amano, Shinichiro Kumita

    SCIENTIFIC WORLD JOURNAL   2012

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    DOI: 10.1100/2012/961986

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  • Delayed-enhancement MRI of apical hypertrophic cardiomyopathy: assessment of the intramural distribution and comparison with clinical symptoms, ventricular arrhythmias, and cine MRI. Reviewed

    Amano Y, Takayama M, Fukushima Y, Kitamura M, Kumita S

    Acta radiologica (Stockholm, Sweden : 1987)   52 ( 6 )   613 - 618   2011.7

  • Assessment of renal impairment by non-contrast-enhanced conventional magnetic resonance imaging: comparison with Tc-99m-DTPA renography Reviewed

    Fumitaka Hidaka, Yasuo Amano, Katsuya Takahama, Ryo Takagi, Ryusuke Murakami, Shiro Onozawa, Shinichiro Kumita

    JAPANESE JOURNAL OF RADIOLOGY   29 ( 6 )   378 - 385   2011.7

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    DOI: 10.1007/s11604-011-0567-9

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  • Time-resolved Three-dimensional Magnetic Resonance Velocity Mapping of Chronic Thoracic Aortic Dissection: A Preliminary Investigation Reviewed

    Yasuo Amano, Tetsuro Sekine, Yuriko Suzuki, Keiji Tanaka, Ryo Takagi, Shinichiro Kumita

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   10 ( 2 )   93 - 99   2011

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    DOI: 10.2463/mrms.10.93

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  • Three-Dimensional Velocity Mapping of Thoracic Aorta and Supra-aortic Arteries in Takayasu Arteritis Reviewed

    Yasuo Amano, Ryo Takagi, Yuriko Suzuki, Tetsuro Sekine, Shinichiro Kumita, Marc van Cauteren

    JOURNAL OF MAGNETIC RESONANCE IMAGING   31 ( 6 )   1481 - 1485   2010.6

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    DOI: 10.1002/jmri.22007

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  • Contrast-Enhanced Myocardial T1-Weighted Scout (Look-Locker) Imaging for the Detection of Myocardial Damages in Hypertrophic Cardiomyopathy Reviewed

    Yasuo Amano, Morimasa Takayama, Shinichiro Kumita

    JOURNAL OF MAGNETIC RESONANCE IMAGING   30 ( 4 )   778 - 784   2009.10

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    DOI: 10.1002/jmri.21921

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  • Noncontrast-Enhanced Three-Dimensional Magnetic Resonance Aortography of the Thorax at 3.0 T Using Respiratory-Compensated T1-Weighted k-Space Segmented Gradient-Echo Imaging With Radial Data Sampling Preliminary Study Reviewed

    Yasuo Amano, Katsuya Takahama, Shinichiro Kumita

    INVESTIGATIVE RADIOLOGY   44 ( 9 )   548 - 552   2009.9

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  • Cardiac Magnetic Resonance Imaging Findings Are Useful for Differentiating Between Hypertrophic Obstructive Cardiomyopathy and Aortic Valve Stenosis in Elderly Patients Reviewed

    Yasuo Amano, Morimasa Takayama, Shinichiro Kumita

    JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY   33 ( 3 )   354 - 358   2009.5

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  • Free-Breathing High-Spatial-Resolution Delayed Contrast-Enhanced Three-Dimensional Viability MR Imaging of the Myocardium at 3.0T: A Feasibility Study Reviewed

    Yasuo Amano, Yoshio Matsumura, Shinichiro Kumita

    JOURNAL OF MAGNETIC RESONANCE IMAGING   28 ( 6 )   1361 - 1367   2008.12

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    DOI: 10.1002/jmri.21595

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  • Arterial visualization by contrast-enhanced moving-table MR angiography: crossover comparison of 0.1 and 0.2 mmol/kg doses of meglumine gadopentetate in normal volunteers. Reviewed International journal

    Hiromitsu Hayashi, Yuji Yuasa, Yasuo Amano, Akihiro Tanimoto, Yoko Saito, Kunihiro Yoshioka, Miho Kita, Tatsuo Kumazaki, Kyoichi Hiramatsu

    Journal of magnetic resonance imaging : JMRI   28 ( 3 )   783 - 90   2008.9

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    PURPOSE: To determine the appropriate dose of contrast medium for moving-table MR angiography (MT-MRA) from the abdominal aorta to the ankle by comparing visualization with different doses of meglumine gadopentetate (Gd-DTPA) administered in crossover fashion to normal volunteers. MATERIALS AND METHODS: Twelve healthy adults underwent imaging after crossover administration of 0.1 and 0.2 mmol/kg of Gd-DTPA in random order. Continuous MT-MRA was performed with a fast 3D spoiled gradient echo sequence without parallel imaging technique. Visualization was evaluated in a total of 252 arteries by three blinded readers who independently rated arterial visualization using a 5-grade scale. Signal intensity was determined and the blood concentration of Gd-DTPA was estimated. RESULTS: Arterial visualization in the lower leg region was significantly better with a dose of 0.2 mmol/kg than with 0.1 mmol/kg (P<0.001). For all regions assessed the estimated blood Gd-DTPA level was significantly higher with 0.2 mmol/kg than with 0.1 mmol/kg (abdominal aorta, P=0.030; superficial femoral artery, P<0.001; posterior tibial artery, P=0.039). The vascular signal enhancement ratio and artery-to-muscle signal ratio were significantly higher in the upper leg and lower leg regions at 0.2 mmol/kg. CONCLUSION: With continuous MT-MRA imaging from the abdomen to the ankle in normal volunteers, better arterial visualization and superior contrast were achieved with 0.2 mmol/kg of Gd-DTPA.

    DOI: 10.1002/jmri.21488

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  • Magnetic resonance imaging of apical left ventricular aneurysm and thinning associated with hypertrophic cardiomyopathy Reviewed

    Amano Yasuo, Takayama Morimasa, Kumita Shinichiro

    JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY   32 ( 2 )   259 - 264   2008.3

  • Non-contrast-enhanced MR angiography of the thoracic aorta using cardiac and navigator-gated magnetization-prepared three-dimensional steady-state free precession Reviewed

    Amano Yasuo, Takahama Katsuya, Kumita Shinichiro

    JOURNAL OF MAGNETIC RESONANCE IMAGING   27 ( 3 )   504 - 509   2008.3

  • Evaluation of global cardiac functional parameters using single-breath-hold three-dimensional cine steady-state free precession MR imaging with two types of speed-up techniques: Comparison with two-dimensional cine imaging Reviewed

    Yasuo Amano, Yuriko Suzuki, Marc van Cauteren

    COMPUTERIZED MEDICAL IMAGING AND GRAPHICS   32 ( 1 )   61 - 66   2008.1

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    DOI: 10.1016/j.compmedimag.2007.09.003

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  • Silicone-selective multishot echo-planar imaging for rapid MRI survey of breast implants Reviewed

    Yasuo Amano, Ritsu Aoki, Shinichiro Kumita, Tatsuo Kumazaki

    EUROPEAN RADIOLOGY   17 ( 7 )   1875 - 1878   2007.7

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    DOI: 10.1007/s00330-006-0533-6

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  • MR imaging evaluation of regional, remote, and global effects of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy Reviewed

    Yasuo Amano, Morimasa Takayama, Shinichiro Kumita, Tatsuo Kumazaki

    JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY   31 ( 4 )   600 - 604   2007.7

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    DOI: 10.1097/rct.0b013e31803151fd

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  • 【心不全 心不全診療ガイドラインを実地診療に活かす】 心不全・セミナー 実地医家の診断と評価の進めかた 心不全を画像(RI、MRI、CT)により診断・評価する

    汲田 伸一郎, 林 宏光, 天野 康雄, 福嶋 善光, 清野 精彦

    Medical Practice   24 ( 5 )   847 - 853   2007.5

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Misc.

  • Long-term prognostic value of ultrastructural features in dilated cardiomyopathy: comparison with cardiac magnetic resonance. International journal

    Tsunenori Saito, Kuniya Asai, Masaki Tachi, Shigeru Sato, Kosuke Mozawa, Akiko Adachi, Yoshihiro Sasaki, Yasuo Amano, Kyoichi Mizuno, Shin-Ichiro Kumita, Wataru Shimizu

    ESC heart failure   2020.3

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    AIMS: This study aims to determine the implications associated with long-term prognosis of heart failure (HF) in patients with dilated cardiomyopathy (DCM) presenting initially as decompensated HF. We stratified the phase of DCM patients without late gadolinium enhancement (LGE) based on ultrastructural changes in cardiomyocytes. METHODS AND RESULTS: Left ventricular (LV) endomyocardial biopsy was performed in 55 consecutive DCM patients with initial decompensated HF. Ultrastructural changes in cardiomyocytes detected by electron microscopy were compared with data including LGE with cardiac magnetic resonance and HF recurrence. Of the 55 DCM patients, 24 (44%) showed LGE, and 26 (47%) showed recurrence decompensated HF, while 23 patients (42%) showed autophagic vacuoles in cardiomyocytes by electron microscopy. Multivariate analysis identified atrial fibrillation [hazard ratio (HR), 3.40; 95% confidence interval (CI), 1.45-7.98], haemoglobin level (HR, 0.82; 95% CI, 0.68-0.99), beta-blocker use (HR, 0.18; 95% CI, 0.05-0.74), and autophagic vacuoles (HR, 0.25; 95% CI, 0.09-0.65) as predictors of HF recurrence in the total patient population. In patients without LGE, only autophagic vacuoles were independent predictors of readmission because of HF (HR, 0.29; 95% CI, 0.09-0.90). In patients with LGE, atrial fibrillation (HR, 19.10; 95% CI, 2.97-123.09), and mid-linear LGE (HR, 12.96; 95% CI, 2.02-82.94) were independent predictors of readmission because of HF. CONCLUSIONS: In DCM patients with LGE, characterised by progression of LV remodelling, the LGE pattern was a predictor of HF recurrence, whereas in patients without LGE, absence of autophagic vacuoles was a predictor of HF recurrence.

    DOI: 10.1002/ehf2.12662

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  • 4D Flow MRI assessment of cerebral blood flow before and after high-flow EC-IC bypass surgery for ICA aneurysm Reviewed International journal

    Orita E, Murai Y, Sekine T, Takagi R, Amano Y, Ando T, Iwata K, Obara M, Matsumura Y, Kumita S

    Neurosurgery   85   58 - 64   2019.5

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  • Glomerulocystic kidney identified in older patients by magnetic resonance imaging: relation to renal function and renal corticomedullary differentiation Reviewed International journal

    Amano Y, Omori Y, Yanagisawa F, Takagi R

    Medicine (Baltimore)   98   e15350   2019.5

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  • Hypointense spleen associated with severe acute pancreatitis on MR Imaging Reviewed

    Amano Y, Takagi R, Yanagisawa F, Ando C

    Magnetic Resonance in Medical Sciences   18   115 - 116   2019.1

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  • Non-contrast-enhanced T1 mapping of dilated cardiomyopathy: comparison between native T1 values and late gadolinium enhancement Reviewed

    Yanagisawa F, Amano Y, Tachi M, Inui K, Asai K, Kumita S

    Magnetic Resonance in Medical Sciences   18 ( 1 )   12 - 18   2019.1

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    J-GLOBAL

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  • Extracellular volume fraction assessed using cardiovascular magnetic resonance can predict improvement of left ventricular ejection fraction in patients with dilated cardiomyopathy Reviewed

    Inui K, Asai K, Tachi M, Yoshinaga A, Izuki Y, Kubota Y, Murai K, Tsukada YT, Amano Y, Kumita S, Shimizu W

    Heart and Vessels   33 ( 10 )   1195 - 1203   2018.8

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    J-GLOBAL

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  • Relationship between extension or texture features of late gadolinium enhancement and ventricular tachyarrhythmias in hypertrophic cardiomyopathy Reviewed International journal

    Amano Y, Suzuki Y, Yanagisawa F, Omori Y, Matsumoto N

    BioMed Research International   409246   2018.1

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  • Cardiac MR imaging of hypertrophic cardiomyopathy: Techniques, findings, and clinical relevance Invited Reviewed

    Yasuo Amano, Mitsunobu Kitamura, Hitoshi Takano, Fumi Yanagisawa, Masaki Tachi, Yasuyuki Suzuki, Shinichiro Kumita, Morimasa Takayama

    Magnetic Resonance in Medical Sciences   17 ( 2 )   120 - 131   2018

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    Language:English   Publishing type:Book review, literature introduction, etc.   Publisher:Japanese Society for Magnetic Resonance in Medicine  

    DOI: 10.2463/mrms.rev.2017-0145

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  • 4D flow MRIを用いた閉塞性肥大型心筋症における乱流エネルギーの定量に関する検討

    岩田琴美, 関根鉄朗, 城正樹, 井守洋一, 松田淳也, 武田美那子, 天野康雄, 新田武史, 小原真, 汲田伸一郎

    日本医学放射線学会秋季臨床大会抄録集   54th   2018

  • Relationship of non-septal late gadolinium enhancement to ventricular tachyarrhythmia in hypertrophic cardiomyopathy Reviewed International journal

    Amano Y, Yanagisawa F, Kitamura M, Tachi M, Kumita S

    Journal of Computer Assisted Tomography   41 ( 5 )   768 - 771   2017.8

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    OBJECTIVE: This study aimed to determine the relationship between the extent and the location of late gadolinium enhancement (LGE) and ventricular tachyarrhythmia or implantable cardioverter defibrillator (ICD) in hypertrophic cardiomyopathy (HCM). METHODS: We enrolled 115 patients with HCM and LGE. The location of LGE was divided into septal and nonseptal segments. Clinical backgrounds and LGE were compared in patients between with and without the arrhythmia or consequent ICD installation. RESULTS: There were significant differences in the number of risk markers, left ventricular ejection fraction, extent of global LGE, and extent of nonseptal LGE between the groups (P < 0.01). Multivariate analysis revealed that the number of risk markers and extent of nonseptal LGE contributed to ventricular tachyarrhythmia or ICD installation (P < 0.01). CONCLUSIONS: The nonseptal LGE is related to ventricular tachyarrhythmia or ICD installation. We should be vigilant for nonseptal LGE when applying LGE to risk stratification for HCM.

    DOI: 10.1097/RCT.0000000000000599

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  • Usefulness of Non-Anteroseptal Region Left Ventricular Hypertrophy Using Cardiac Magnetic Resonance to Predict Repeat Alcohol Septal Ablation for Refractory Obstructive Hypertrophic Cardiomyopathy Reviewed

    Mitsunobu Kitamura, Yasuo Amano, Morimasa Takayama, Junsuke Shibuya, Junya Matsuda, Hideto Sangen, Shunichi Nakamura, Hitoshi Takano, Kuniya Asai, Shinichiro Kumita, Wataru Shimizu

    AMERICAN JOURNAL OF CARDIOLOGY   120 ( 1 )   124 - 130   2017.7

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  • Evaluation of myocardial glucose metabolism in hypertrophic cardiomyopathy using 18F-fluorodeoxyglucose positron emission tomography Reviewed International journal

    Aoyama R, Takano H, Kobayashi Y, Kitamura M, Asai K, Amano Y, Kumita S, Shimizu W

    PLoS One   12 ( 11 )   e0188479   2017.1

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    BACKGROUND: The purposes of this study were to assess the usefulness of myocardial 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) for evaluating myocardial metabolic status in hypertrophic cardiomyopathy (HCM) and the therapeutic efficacy of alcohol septal ablation (ASA) in hypertrophic obstructive cardiomyopathy (HOCM). METHODS: Thirty HCM patients (64.4±10.5 years, 14 male, 12 hypertrophic non-obstructive cardiomyopathy [HNCM], 16 HOCM, and 2 dilated phase of HCM) underwent 18F-FDG-PET/CT. 18F-FDG uptake was semi-quantitatively evaluated using an uptake score in each 17 segment and the entire LV or regional standardized uptake value (SUV). RESULTS: 18F-FDG uptake was observed mostly in a hypertrophied myocardium in HNCM patients, whereas 18F-FDG was extensively accumulated beyond the hypertrophied myocardium in HOCM patients. There was a positive correlation between the summed uptake score of 18F-FDG and high-sensitive troponin T level in HNCM patients (r = 0.603, p = 0.049), whereas the score was positively correlated with brain natriuretic peptide level (r = 0.614, p = 0.011) in HOCM patients. In 10 patients who received ASA, the maximum SUV of the entire LV was significantly reduced from 5.6±2.6 to 3.2±2.1 (p = 0.040) after ASA. Reduction of that maximum SUV was particularly significant in the lateral region (from 5.5±2.6 to 2.9 ±2.2, p = 0.024) but not significant in the anteroseptal region (from 4.5±2.6 to 2.9±1.6, p = 0.12). CONCLUSION: Extensive 18F-FDG uptake beyond the hypertrophied myocardium was observed in HOCM. ASA attenuates 18F-FDG uptake in a remote lateral myocardium.

    DOI: 10.1371/journal.pone.0188479

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  • MRI texture analysis of background parenchymal enhancement of the breast Reviewed International journal

    Amano Y, Woo J, Amano M, Yanagisawa F, Yamamoto H, Tani M

    BioMed Research International   4845909   2017.1

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  • Three-dimensional Cardiac MR Imaging: Related Techniques and Clinical Applications Reviewed

    Yasuo Amano, Fumi Yanagisawa, Masaki Tachi, Kuniya Asai, Yasuyuki Suzuki, Hidenobu Hashimoto, Kiyohisa Ishihara, Shinichiro Kumita

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   16 ( 3 )   183 - 189   2017

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    DOI: 10.2463/mrms.rev.2016-0116

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  • 【症例から学ぶMRIの基礎-臨床に直結する知識-】心臓

    天野 康雄, 城 正樹, 柳沢 芙美, 橋本 英伸, 今井 祥吾, 汲田 伸一郎, 石原 聖久

    画像診断   37 ( 1 )   42 - 49   2016.12

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  • Relationship of postcontrast myocardial T1 value and delayed enhancement to reduced cardiac function and serious arrhythmia in dilated cardiomyopathy with left ventricular ejection fraction less than 35%.

    Masaki Tachi, Yasuo Amano, Kensuke Inui, Minako Takeda, Fumi Yamada, Kuniya Asai, Shinichiro Kumita

    Acta Radiologica   57 ( 4 )   430 - 436   2016.4

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  • Fast 3-breath-hold 3-dimensional tagging cardiac magnetic resonance in patients with hypertrophic myocardial diseases: a feasibility study.

    Amano Y, Yamada F, Hashimoto H, Obara M, Asai K, Kumita S

    BioMed Research International   2016.2

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  • 【知っておきたい循環器疾患のCT・MRI(1)-心臓・頸部血管疾患Case Review-】 心臓 心アミロイドーシス

    今井 祥吾, 天野 康雄, 城 正樹, 町田 幹, 汲田 伸一郎

    画像診断   35 ( 8 )   936 - 937   2015.6

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    DOI: 10.15105/J00235.2015304794

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  • Clinical Predictors for Repeat Alcohol Septal Ablation in Refractory Hypertrophic Obstructive Cardiomyopathy

    Mitsunobu Kitamura, Morimasa Takayama, Yasuo Amano, Junsuke Shibuya, Junya Matsuda, Aya Yoshinaga, Syunichi Nakamura, Kuniya Asai, Hitoshi Takano, Wataru Shimizu

    CIRCULATION   130   2014.11

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  • In vivo comparison between myocardial fibrosis and myocardial extracellular volume (ECV) measurement by cardiovascular magnetic resonance (CMR)

    K. Inui, M. Tachi, T. Saito, Y. Kubota, K. Murai, K. Kato, H. Takano, Y. Amano, K. Asai, W. Shimizu

    EUROPEAN HEART JOURNAL   35   176 - 177   2014.9

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  • Clinical characteristics and cardiac magnetic resonance for the patients received repeat percutaneous transluminal septal myocardial ablation in refractory hypertrophic obstructive cardiomyopathy

    M. Kitamura, Y. Amano, J. Shibuya, J. Matsuda, S. Nakamura, H. Takano, K. Asai, M. Takayama, W. Shimizu

    EUROPEAN HEART JOURNAL   35   1084 - 1084   2014.9

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  • MOLLI法を用いた心臓MRIでのextracellular volume(ECV)測定と心筋生検組織における線維化の比較

    乾 恵輔, 城 正樹, 斎藤 恒徳, 吉永 綾, 久保田 芳明, 加藤 浩司, 高野 仁司, 天野 康雄, 浅井 邦也, 清水 渉

    日本心臓病学会学術集会抄録   62回   O - 262   2014.9

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  • Prognostic Utility of Myocardial Autophagy and Ultrastructural Findings in Early Dilated Cardiomyopathy: Comparison With Cardiac Magnetic Resonance

    Tsunenori Saito, Kuniya Asai, Shigeru Sato, Yasuo Amano, Hitoshi Takano, Kyoichi Mizuno, Wataru Shimizu

    CIRCULATION   128 ( 22 )   2013.11

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  • 好酸球性心筋炎のMRI

    谷 瞳, 天野 康雄, 城 正樹, 町田 幹, 汲田 伸一郎, 水野 杏一

    Japanese Journal of Radiology   31 ( Suppl.I )   25 - 25   2013.2

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  • Clinical significance of detecting abnormal fatty acid metabolism with iodine-123 15-(p-iodophenyl)-3-(R, S) methylpentadecanoic acid imaging in patients with dilated cardiomyopathy

    A. Yoshida, H. Takano, T. Saito, S. Nakamura, S. Tara, G. Takagi, K. Asai, S. Kumita, Y. Amano, K. Mizuno

    EUROPEAN HEART JOURNAL   33   246 - 246   2012.8

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  • Hepatosplenic and Muscular Sarcoidosis: Characterization with MR Imaging

    Tetsuro Sekine, Yasuo Amano, Fumitaka Hidaka, Ryo Takagi, Tadashi Machida, Zenya Naito, Shinichiro Kumita

    MAGNETIC RESONANCE IN MEDICAL SCIENCES   11 ( 2 )   83 - 89   2012

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  • T2-Weighted Cardiac Magnetic Resonance Imaging of Edema in Myocardial Diseases

    Yasuo Amano, Masaki Tachi, Hitomi Tani, Kyoichi Mizuno, Yasuhiro Kobayashi, Shinichiro Kumita

    SCIENTIFIC WORLD JOURNAL   2012

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    DOI: 10.1100/2012/194069

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Presentations

  • Myocardial T1 and extracellular volume fraction related to cardiac functional parameters in dilated cardiomyopathy. International conference

    Tachi M, Amano Y, Imai S, Yamada F, Obara M, Inui K, Kumita S

    101st annual meeting of Radiological Society of North America  2015.11  Radiological Society of North America

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    Venue:Chicago  

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  • Clinical significance of the regional and global myocardial T1 value and extracellular volume fraction in hypertensive cardiomyopathy

    Tachi M, Amano Y, Inui K, Asai K, Kumita S

    75th annual meeting of Japan Radiological Society  2016.4  日本医学放射線学会

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    Venue:横浜  

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  • Contrast-enhanced steady-state free precession in the assessment of hypertrophic cardiomyopathy after percutaneous transluminal septal myocardial ablation. International conference

    Yamada F, Amano Y, Tachi M, Imai S, Kumita S

    101st annual meeting of Radiological Society of North America  2015.11  Radiological Society of North America

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    Venue:Chicago  

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  • 4D Flow MRI analysis of cerebral blood flow before and after EC-IC bypass surgery. International conference

    Orita E, Sekine T, Takagi R, Amano Y, Murai Y, Obara M, Ando T, Matsumura Y, Kumita S.

    25th annual meeting of International Society for Magnetic Resonance in Medicine  2017.4  International Society for Magnetic Resonance in Medicine

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    Venue:Honolulu  

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  • T1 mapping of myocardial fibrosis in patients with non-ischemic heart failure: comparison with late gadolinium enhancement. International conference

    Yamada F, Amano Y, Tachi M, Imai S, Kumita S

    102nd annual meeting of Radiological Society of North America  2016.12  Radiological Society of North America

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    Venue:Chicago  

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  • Flow assessment of ophthalmic artery flow in patients with atherosclerotic internal carotid artery stenotic disease. International conference

    Sekine T, Takagi R, Amano Y, Murai Y, Fukushima Y, Orita E, Ando T, Matsumura Y, Kumita S

    25th annual meeting of International Society for Magnetic Resonance in Medicine  2017.4  International Society for Magnetic Resonance in Medicine

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    Venue:Honolulu  

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  • Distribution and significance of myocardial hyperintensity on T2-weighted MRI of hypertrophic cardiomyopathy International conference

    Amano Y, Mine K, Yamada F, Kumita S

    23rd annual meeting of International Society for Magnetic Resonance in Medicine, Toronto  2015.6  International Society for Magnetic Resonance in Medicine, Toronto

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  • Effect of blood T1 value on extracellular volume fraction in dilated cardiomyopathy with septal scarring

    Amano Y, Tachi M, Inui K, Yamada F, Obara M, Imai S, Kumita S

    23rd annual meeting of International Society for Magnetic Resonance in Medicine  2015.6  International Society for Magnetic Resonance in Medicine

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  • Myocardial hyperintensity on T2-weighted MRI of hypertrophic cardiomyopathy: distribution and clinical significance related to phenotypes. International conference

    Imai S, Amano Y, Yamada F, Aita K, Tachi M, Obara M, Kumita S

    101st annual meeting of Radiological Society of North America  2015.11  Radiological Society of North America

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    Venue:Chicago  

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  • Association between late gadolinium enhancement and three types of ventricular tachyarrhythmia in patients with hypertrophic cardiomyopathy International conference

    Amano Y, Yamada F, Kitamura M, Imai S, Tachi M, Takayama M, Kumita S

    101st annual meeting of Radiological Society of North America  2015.11  Radiological Society of North America

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    Venue:Chicago  

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Awards

  • 日本磁気共鳴医学会国際飛躍賞

    2002.9   日本磁気共鳴医学会  

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    Award type:International academic award (Japan or overseas) 

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  • 日本放射線専門医会MR研究者フェローシップ

    1997.5   日本放射線専門医会  

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Research Projects

  • 非虚血性心筋症おけるびまん性線維化の分布様式と致死性不整脈の関連性:心臓MRI(CMR) MOLLI法を用いた検討

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  • MRI T1T2 mappingを用いた腎機能障害関連心筋症の重症度評価

    基盤研究C

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    Authorship:Principal investigator  Grant type:Competitive

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  • 安定型狭心症における適切性使用基準(AUC)の医療経済効果

    基盤研究C

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  • 3次元タギングMRI を用いた心不全の予後予測

    Grant-in-Aid for Scientific Research (C)

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    Authorship:Principal investigator  Grant type:Competitive

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