Language：English   Publishing type：Research paper (scientific journal)  

Although serum markers such as carcinoembryonic antigen (CEA) and carbohydrate antigen (CA19-9) have been widely used in screening for pancreatic cancer (PC), their sensitivity and specificity are unsatisfactory. Recently, a novel tool of analyzing serum using the short-time Fourier transform (STFT) of free induction decays (FIDs) obtained by 1H-NMR has been introduced. We for the first time evaluated the utility of this technology as a diagnostic tool for PC. Serum was obtained from PC patients before starting any treatments. Samples taken from individuals with benign diseases or donors for liver transplantation were obtained as controls. Serum samples from both groups underwent 1H-NMR and STFT of FIDs. STFT data were analyzed by partial least squares discriminant analysis (PLS-DA) to clarify whether differences were apparent between groups. As a result, PLS-DA score plots indicated that STFT of FIDs enabled effective classification of groups with and without PC. Additionally, in a subgroup of PC, long-term survivors (≥ 2 years) could be discriminated from short-term survivors (< 2 years), regardless of pathologic stage or CEA or CA19-9 levels. In conclusion, STFT of FIDs obtained from 1H-NMR have a potential to be a diagnostic and prognostic tool of PC.

DOI： 10.1038/s41598-020-79087-3

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Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：SPRINGER  

Purpose The aim of this study was to develop the method for the qualitative analysis of zolpidem and its metabolites M-1 to M-4 using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in human blood and urine. Methods To obtain analytical standards, a method for synthesizing zolpidem metabolites M-1 to M-4 was developed. A combination of a copper-catalyzed three-component coupling reaction and pyrrolidine-catalyzed imine formation was adopted to synthesize the methyl esters of M-1 (M-1-Me) and M-2 (M-2-Me), which were hydrolyzed to afford M-1 and M-2, respectively. M-3 and M-4 were also synthesized. The LC-MS/MS conditions were optimized using authentic standards. M-1 to M-4 were analyzed in human blood and urine. Results M-1 to M-4 were successfully synthesized. The mass spectra of M-1 and M-2 were almost identical, but their peaks were chromatographically separated using a octadecyl silica column. Likewise, mass spectra of M-3 and M-4 were similar, but their peaks were chromatographically separated. The peak intensities of the metabolites in human blood and urine were M-1 > M-2, and M-4 > M-3; M-3 was detected only in urine. The presence of other hydroxyzolpidems was also revealed. Conclusions Chromatographic separation of M-1 and M-2 and that of M-4 and other hydroxyzolpidems is necessary to analyze zolpidem metabolites in biological matrices because their mass spectra are quite similar. This study is the first to analyze zolpidem and M-1 to M-4 simultaneously using LC-MS/MS, which can provide more compelling evidence of zolpidem intake.

DOI： 10.1007/s11419-020-00551-w

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Language：Japanese   Publisher：(一社)日本神経学会  

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Language：Japanese   Publisher：日本医科大学医学会  

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DOI： 10.5650/jos.ess18212

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DOI： 10.1016/j.legalmed.2018.09.021

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Language：Japanese   Publishing type：Research paper (scientific journal)  

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：ELSEVIER IRELAND LTD  

Cerebrospinal fluid (CSF) is routinely subjected to gross evaluation in postmortem investigations; however, its use in chemical evaluations has not been fully realized. Analysis of nuclear magnetic resonance (NMR) spectra with pattern recognition methods was applied to CSF samples. Rats were treated with pentylenetetrazol (PTZ) to induce seizure or pentobarbital (PB) to induce coma, and postmortem CSF was collected after CO2 gas euthanization. Pattern recognition analysis of the NMR data was performed on individual postmortem CSF samples. The aim of this study was to determine if pattern recognition analysis of NMR data could be used to classify the rats according to their drug treatment. The applicability of NMR data with pattern recognition analysis using postmortem CSF was also assessed. Partial Least Squares-Discriminant Analysis (PLS-DA) score plots indicated that the PTZ, PB, and NS (control) groups were clustered and clearly separated. PLS-DA correlation loading plots showed respective spectral and category variances of 41% and 42% for factor 1, and 17% and 27% for factor 2. Thus, factors 1 and 2 together described 58% (41% + 17%) and 69% (42% + 27%) of the variation, respectively. NMR study of postmortem CSF has the potential to be utilized as both a novel forensic neurochemistry method and in the clinical setting. (C) 2017 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.legalmed.2017.01.004

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Language：Japanese   Publisher：(一財)厚生労働統計協会  

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Language：Japanese   Publisher：(NPO)日本法医学会  

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：LIPPINCOTT WILLIAMS & WILKINS  

We present an autopsy case of a pregnant woman who was a victim of domestic violence. The deceased showed injuries mainly to her head and abdomen. Postmortem examination revealed 1400 mL of abdominal hemorrhage, ablation of the perimetrium, placental avulsion, and intracranial hematoma. The cause of death was diagnosed as hemorrhagic shock. The uterus contained a fetus of 7 months' gestational age. Fetal autopsy revealed laceration of the lungs, laceration and avulsion of the liver, and 15 mL of hemoperitoneum. Both placental and fetal injuries suggested repeated severe attacks to the abdomen, such as those expected to result from kicking or hitting.

DOI： 10.1097/PAF.0b013e318219c8bb

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Purpose: The purpose of this investigation was to compare magnetization-prepared rapid gradient echo (MP-RAGE) images with T1-weighted images (T1WI) and T2-weighted images (T1W2) of postmortem brain tissue fixed by admixtures of formalin and gadoteridol. We additionally sought to explore the feasibility of using fixed brain magnetic resonance imaging (MRIs) in forensic practices.
Methods: Specimens included in the study were eight whole brains that had been removed during forensic autopsy. Brain specimens were randomly divided into three groups and MRIs were performed either (A) the day of autopsy (n = 2) on unfixed tissue, (B) after immersion fixation in 20% formalin (n = 3), or (C) after immersion fixation in 20% formalin mixed with 4 mL/L ProHance (R) (gadoteridol) (n = 3). T1WI, T2WI, and MP-RAGE images of all group samples were acquired with a 3T clinical MR scanner. Gray and white matter contrasts of the cortex and basal nucleus in every fixation group and image sequence were then visually compared.
Results: Gray/white matter contrasts of the cortex were good in all images obtained by MP-RAGE, and T1WI5 of specimens fixed by formalin and gadoteridol-mixed formalin. Additionally, gray/white matter contrast in the basal nucleus was sufficient in the MP-RAGE sequence of specimens fixed by gadoteridol-mixed formalin.
Conclusions: MRI of brains immersion-fixed in formalin and gadolinium could serve as a promising tool for neuropathological assessment in forensic practices. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2014.03.003

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Language：Japanese   Publisher：防衛医科大学校雑誌編集委員会  

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Injuries by handcrafted firearms are uncommon, and those by handcrafted shotguns are very rare. We present an unusual case of suicide using a handcrafted shotgun and slug. A 73-year-old male, who was a glass-grinding artisan, was found dead at a workshop on the premises of his residence. Autopsy showed a contact shotgun wound to the forehead, which perforated the cranium and caused extensive damage to the brain. The handcrafted shotgun was found in the proximity of the body. The shotgun consisted of metal pipes fixed to the vise and did not take the form of a conventional gun. The recovered slug was also found to be manufactured manually. It appeared that the handcrafted shotgun was only intended for committing suicide using his ballistics knowledge, skills, and resources. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2013.12.005

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The deceased was an unidentified young male found unconscious on a walkway. On autopsy, outer and inner fistulae of the left temporal bone, subcutaneous abscess in the left side of the neck and head, and an intracranial abscess were noted. A portion of the left temporal bone was removed and scanned by cone-beam computed tomography (CT) (normally used for dentistry applications) to evaluate the lesion. The cone-beam CT image revealed roughening of the bone wall and hypolucency of the mastoid air cells, consistent with an inflammatory bone lesion. According to autopsy and imaging findings, the cause of death was diagnosed as intracranial abscess with Bezold's abscess secondary to left mastoiditis as a complication of otitis media. Although determining the histopathology of bone specimens is time-consuming and costly work, we believe that use of cone-beam CT for hard tissue specimens can be useful in forensic practice. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2013.09.001

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Language：Japanese   Publisher：(一財)厚生労働統計協会  

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Other Link： http://search.jamas.or.jp/link/ui/2014001878

Language：Japanese   Publisher：(NPO)日本法医学会  

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Language：English   Publisher：防衛医科大学校雑誌編集委員会  

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DOI： 10.2147/oaem.s33063

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Magnetic resonance imaging thermometry has been introduced as a technique for measurement of temperature changes in cooling dead rats. Rat pelvic magnetic resonance images were acquired sequentially more than 2 h after euthanasia by halothane overdose. A series of temperature difference maps in cooling dead rats was obtained with calculating imaging phase changes induced by the water proton frequency shift caused by temperature changes. Different cooling processes were monitored by the temperature difference maps in the rats. Magnetic resonance imaging thermometry applied in the study of laboratory animals could theoretically reproduce a variety of causes of death with different environmental conditions. Outcomes from experimental animal studies could be translated into a temperature-based time of death estimation in forensics. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2011.07.005

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Language：Japanese   Publisher：(一財)厚生労働統計協会  

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Other Link： http://search.jamas.or.jp/link/ui/2009288438

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A man in his thirties was found dead in his room. The autopsy findings were as follows: multiple bruises and subdermal edema, small sized stab wounds, a number of skin scars, new and old rib fractures, mild liver contusion, and marked myositis ossificans traumatica (MOT) at both thighs. In particular, the MOT was closely associated with repetitive physical assault and battery. The deceased did not have any lethal injuries of internal organs or great vessels, and the cause of death was diagnosed as traumatic hypovolemic shock. The deceased seemed to have accepted as fate his "specific situation" in which he would be subjected to continued physical violence from his cohabiter, a woman in her thirties. © 2008 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2008.02.004

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We assessed the gas dispersal potential of bedding articles used by 14 infants diagnosed with sudden unexpected infant death at autopsy. Of these cases, eight exhibited FiCO(2) values greater than 10% within 2.5 min, six of which were found prone and two supine. The results demonstrated that these eight beddings had a high rebreathing potential if they covered the babies' faces. We did not, however, take into account in our model the large tissue stores of CO2. As some bicarbonate pools will delay or suppress the increase of FiCO(2), the time-FiCO(2) graphs of this study are not true for living infants. This model, however, demonstrated the potential gas dispersal ability of bedding. The higher the FiCO(2) values, the more dangerous the situation for rebreathing infants. In addition, FiO(2) in the potential space around the model's face can be estimated mathematically using HCO2 values. The FiO(2) graph pattern for each bedding item corresponded roughly to the inverse of the FiCO(2) time course. The FiO(2) of the above eight cases decreased by 8.5% within 2.5 min. Recent studies using living infants placed prone to sleep reported that some babies exhibited larger decreases in FiO(2) than increases observed in FiCO(2). While the decrease of FiO(2) in our model is still theoretical, CO2 accumulation and O-2 deprivation are closely related. If a striking O-2 deficiency Occurs in a short period, babies can lose consciousness before an arousal response is evoked and all infants could be influenced by the poor gas dispersal of bedding: the main cause of sudden death in infancy would thus be asphyxia. When the bedding is soft, the potential for trapping CO2 seems to be high; however, it is impossible to assess it by appearance alone. We Sought to provide some objective indices for the assessment of respiratory Compromise in relation to bedding using our model. When a baby is found unresponsive with his/her face covered with poor gas dispersal bedding, we should consider the possibility of asphyxia. (C) 2008 Elsevier Ireland Ltd. All Fights reserved.

DOI： 10.1016/j.forsciint.2008.07.006

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An 86-year-old man suffering from right hemiparesis and dementia fell from a stretcher and sustained laceration and bruising to his right eyebrow. He was brought to an emergency room, and his wounds were treated. Shortly after discharge, his respiratory and mental status dramatically declined. Despite supportive care, he died about three hours after re-admission. Autopsy revealed a minor laceration to the eyebrow with minor intracranial injuries, mild cardiomegaly (370 g) with right atrial dilatation, pericardial effusion (170 ml) and marked pulmonary edema. Microscopically, fatty droplets were observed in the lung capillaries, the glomeruli and the intracerebral vessels. Although the extent of the original injuries seemed insufficient to cause systemic fat embolism syndrome (FES), the patient's decreased cardiac reserves and stress associated with this event likely contributed to his death consistent with the physiochemical model of FES pathogenesis. © 2007 Elsevier Ltd and FFLM.

DOI： 10.1016/j.jflm.2007.03.010

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A human male mandible was found under the eaves of a house. There were no associated items that allowed for personal identification. An anthropologist, who voluntarily joined our forensics team to give an expert opinion, found two small linear marks of 0.6 cm on the surface of the right condylar process. He thought these marks had been produced by a sharp object, and at the very least were not the result of bite marks by rodents or other animals. At first, the police did not appreciate the significance of the marks. One month later, however, other remains with similar marks were found near the scene, strongly suggesting that the case was a mutilation murder with a sharp weapon. After a vigorous search, the police obtained information that a young man in his twenties had gone missing in the area one year previously. After checking up on his relationships, a suspect was identified and arrested. The suspect subsequently confessed and was convicted as guilty of the crime. There are only a few forensic anthropologists in Japan. Consequently, almost all cases requiring bone examination have been handled by forensic pathologists, but it is hard for forensic pathologists to cover all fields comprehensively. The present case might have been solved without help from the anthropologist. However, we believe that forensic pathologists, especially less experienced ones, should seek advice from an expert in the field of forensic anthropology in order to carry a multidisciplinary forensic investigation. Given the current situation in, it is difficult in many institutes of forensics to obtain direct help from forensic anthropologists. The authors believe that collaborative networking via the Internet between forensic experts in each field cannot only obtain further information on complicated cases, but would also be helpful in training young forensic pathologists. © 2007 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2007.06.003

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A young man presented to the emergency department with mental status changes, severe metabolic acidosis, and oliguria. Acute ethylene glycol intoxication was diagnosed. The patient suffered clinical brain death three days after admission despite intensive care and continuous hemodiafiltration. The patient died one month after admission. Autopsy revealed acute tubular necrosis of the kidneys with significant calcium oxalate depositions. The brain was markedly softening and with chronic meningoencephalitis and dural sinus thrombosis. We considered that the amount and the persistence of the calcium oxalate deposition in the kidney may afford a best clue to the postmortem diagnosis of ethylene glycol poisoning even in the chronic stage. © 2007 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2007.05.010

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A young man with a prior left temporal craniotomy was brought to the emergency room after being beaten, including a blunt trauma to the head. After receiving a cranial X-ray, the patient was discharged home. He was found in a deep coma eight hours later. Autopsy revealed an approximately 4 × 5 cm bone fragment fixed to the left temporal bone, except at the inferior margin, where it had no osseous connection. There were a 44 g subdural hematoma in the left frontotemporal region, small hematomata within the left temporal lobe, and bilateral subarachnoid hemorrhage. Microscopically, we detected ruptured choroid plexus at the surface of the left temporal lobe. We speculated that the combination of the unfixed bone fragment and hyperplastic choroid plexus after craniotomy increased the decedent's vulnerability to external trauma at that site. © 2007 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2007.04.005

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Language：Japanese   Publisher：法医学談話会  

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：SPRINGER  

Beginning 7 h after death, a datalogger was used to measure the temperature in the external auditory canal of an adult male body placed in a refrigerated room. The sequence of measured values approximated a single exponential function with a correlation coefficient of 0.998475. This suggests that the starting time of body cooling in the refrigerated room under constant temperature can be calculated with less error using any two data points recorded by the datalogger. However, the results of such calculations varied widely and longer postmortem intervals demonstrated greater calculation errors. Periodic errors also appeared. Mathematical simulations showed that this variation was caused by rounding errors, which represent the difference between the thermometer readings and the true temperature. The resolution of the thermometer was 0.1 degrees C, a normal specification; however, even this led to noticeable rounding errors. Therefore, significant errors may influence postmortem interval estimations using other body temperatures. When body temperatures are used to determine the time of death, a method that minimizes rounding errors should be considered.

DOI： 10.1007/s00414-006-0088-8

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Introduction: A simulation using a computer model was undertaken to investigate postmortem cooling patterns in the outer ear. Methods: Cooling patterns were analyzed using a 3-dimensional head model built from brain CT images of a volunteer. The simulation was verified with a case subject under constant environmental conditions to obtain an appropriate heat transmission coefficient. Results: The cooling pattern of the head model agreed with that of the case subject when the heat transmission coefficient was 6 W/m2 °C, and it could be approximated to a single exponential curve. Discussion: This is the first simulative study to show the postmortem cooling pattern of the head of an adult human. Our head model will prove useful to predict the cooling patterns of not only the outer ear but also of the entirety of the head. © 2006 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2006.09.006

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We performed automatic continuous monitoring of rectal and ambient temperatures using button-type thermo data loggers in autopsy cases. The button-type data loggers have a battery-powered memory that can record 2048 temperature readings. The measurement intervals and other initial settings are determined by computer software, and the measurements were taken at 5-min intervals for this study. At autopsy, the data loggers were retrieved and recorded temperature graphs were produced. This study obtained three representative cases. In one case, the button-type data logger was not discharged regardless of how the body was moved after the device was inserted into the rectum. In two other cases, the cooling curves of the rectal temperature readings clearly followed changes in ambient cooling conditions. The advantages of the tested devices are their small size (diameter, 17.4 mm
thickness, 5.9 mm) and ease of insertion into the rectum, requiring no special skills. Many temperature-based algorithms to determine time of death have been developed, and as a matter of course, the temperature values must be accurate and reliable. Ensuring the validity of each temperature reading requires continuous data from an internal data logger. A button-type data logger is ideal for this purpose. © 2006 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2006.04.001

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：ELSEVIER IRELAND LTD  

Haplotypes and allele frequencies of 12 Y-STRs were examined in a population sample of 381 Japanese male volunteers. A total of 315 haplotypes were identified, of which 288 haplotypes were unique, and 18, three, three, two, one and one were found in two, three, four, five, eight and 18 individuals, respectively. Total gene diversity was 0.997. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.forsciint.2005.04.035

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An 8-month-old female baby was found collapsed in the prone position 30 min after being positioned under soft-bedding. She was taken to the emergency room with cardiopulmonary arrest. Her heartbeat was recovered after resuscitation and continued for 20 h under artificial respiration, at which point the child died. At autopsy, the child showed no significant pathological abnormalities apart from a thyroglossal duct cyst of 2.0 cm diameter, therefore, it seemed that the cyst, which was close to the epiglottis, had caused asphyxia through airways occlusion. However, the child had shown no respiratory problems before death, and the risk of airway occlusion as a result of lingual cysts is more likely in a supine rather than a prone position. A small amount of evidence suggested that the child died as a result of suffocation from being covered by soft-bedding, which could have caused fatal asphyxia; it is also possible that a hypoxic state induced by airway obstruction might have been enhanced by being covered with bedding. It seemed reasonable to assume that death was caused by a combination of the lingual thyroglossal duct cysts and asphyxia caused by being covered in bedding, though the main factor appeared to be the large cyst. (C) 2005 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.forsciint.2004.12.032

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Language：Japanese   Publisher：法医学談話会  

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An autopsy was conducted on a male showing leather-like skin damage, revealing the cause of death to be an injury to the head. Thinner was found scattered around the scene of death, and stomach and intestine contents smelled strongly of solvent. Toxicological analysis was conducted to determine whether or not the solvent was of a lethal level. Using gas chromatography, peaks of toluene, xylene, and ethylbenzene were detected in the blood and gastric contents. No toluene was detected in the urine, and therefore it was concluded that the decedent died of a severe head injury shortly after solvent ingestion. In the literature, toluene concentrations in blood and lung samples were determined as both fatal and non-fatal but clear differences in the fatality of toluene in solid organ samples, namely, the brain, liver and kidneys were shown. The brain is especially useful in postmortem analysis. In this case, the concentration of toluene in the brain was 20.0 mul/g, which was considered as a non-lethal level. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.forsciint.2004.03.036

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Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier  

To examine the state of ketoacidosis in relation to the cause of death, three kinds of ketone bodies (acetoacetate, beta-hydroxybutyrate and acetone) were measured in postmortem serum. Of 100 autopsy cases, 22 had ketone body increasing pathophysiological conditions, overlapped in some cases, namely a poorly-nourished state (10 cases), alcoholic fatty liver damage (10), diabetes (5) and infectious disease (5). Of the 3, 11, 7 and 15 cases in which the beta-hydroxybutyrate concentration was greater than 10,000, 1000-10,000, 500-1000 and 200-500 μmol/l, 3 (100%), 8 (73%), 3 (43%) and 5 (33%), respectively, had one or more pathophysiological conditions that usually produce ketone bodies. Of the 64 cases in which the beta-hydroxybutyrate concentrations were less than 200 μmol/l, only 3 (5%) had some of these conditions. Cases showing high levels of ketone bodies tended to have pathophysiological states that can produce them, although the level of beta-hydroxybutyrate and these states did not show parallel relationships. When autopsy findings fail to explain the cause of death, a diagnosis as death caused by ketoacidosis would be reasonable if the serum beta-hydroxybutyrate level is over 1000 μmol/l and the body has pathophysiological conditions that tend to increase ketone bodies. © 2005 Elsevier Ireland Ltd. All rights reserved.

DOI： 10.1016/j.legalmed.2005.01.003

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Presentation type：Poster presentation  

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Presentation type：Public lecture, seminar, tutorial, course, or other speech  

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Language：Japanese   Presentation type：Poster presentation  

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Language：English   Presentation type：Poster presentation  

Venue：Fukuoaka  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

Venue：横浜  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：岐阜  

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Language：English   Presentation type：Oral presentation (invited, special)  

Venue：広州/Guangzhou  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：横須賀  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：高知  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：所沢  

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Language：Japanese   Presentation type：Poster presentation  

Venue：高知  

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Language：Japanese   Presentation type：Poster presentation  

Venue：福岡  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：English   Presentation type：Poster presentation  

Venue：Fukuoaka  

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Language：English   Presentation type：Poster presentation  

Venue：Fukuoaka  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：横浜  

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Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

Venue：津  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：札幌  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：徳島  

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Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：札幌  

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Language：Japanese   Presentation type：Poster presentation  

Venue：高崎市?  

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Language：Japanese   Presentation type：Poster presentation  

Venue：高崎市?  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：浜松  

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Language：Japanese   Presentation type：Poster presentation  

Venue：京都  

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Language：Japanese   Presentation type：Poster presentation  

Venue：浜松  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：浜松  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：福島  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：小倉  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：札幌  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：埼玉  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：札幌  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：仙台  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：福島  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：福島  

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Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

Venue：東京  

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Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：English   Presentation type：Poster presentation  

Venue：Stockholm  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：大阪  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：大阪  

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Language：Japanese   Presentation type：Poster presentation  

Venue：東京  

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Language：Japanese   Presentation type：Poster presentation  

Venue：大阪  

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Language：Japanese   Presentation type：Poster presentation  

Venue：横浜  

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Language：Japanese   Presentation type：Poster presentation  

Venue：長崎  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：仙台  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：仙台  

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Language：Japanese   Presentation type：Oral presentation (general)  

Venue：仙台  

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Language：Japanese   Presentation type：Poster presentation  

Venue：秋田  

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